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  1. Book ; Online: COVID-19 Outbreak and Beyond : Psychological and Behavioral Responses and Future Perspectives

    Roma, Paolo / Monaro, Merylin / Mazza, Cristina

    2022  

    Keywords Psychology ; risk perception ; confidence ; social support ; coping strategy ; COVID-19 ; SARS-CoV-2 ; older adults ; depression ; precautionary behavior ; socioeconomic status ; online survey ; mental health ; health anxiety ; intrusive thoughts ; contamination ; negative affect ; pandemic ; psychopathology ; psychiatric patients ; mental illness ; cognitive function ; psychiatric symptoms ; lockdown ; Information and Communications Technology (ICT) ; social connectedness ; future anxiety ; social media ; technology and society ; gender differences ; students ; anxiety ; personality ; coronavirus ; lifestyle ; behavioral determinants ; healthcare utilization ; healthcare avoidance ; public health ; self-efficacy ; risk-taking ; young adult ; stress ; coronavirus pandemic ; emotion regulation ; primary emotional systems ; mental and physical health ; COVID-19 pandemic ; quarantine ; isolation ; public health emergency preparedness ; online survey of patients and contacts ; intention-based critical factors ; novel coronavirus ; pandemic prevention ; hybrid theoretical framework ; path modeling ; Pakistan ; service robot ; customer engagement ; protection motivation theory ; social distancing ; COVID-19 preventative behaviors ; perceived susceptibility ; cues to action ; health belief model ; health education ; Okara, Pakistan ; occupational stress ; emotional intelligence ; precaution measures ; Saudi Arabia ; institutional climate ; COVID-19 preventive behaviors ; extended theory of planned behavior ; university students ; pandemics ; psychological distress ; longitudinal studies ; fear ; acute myocardial infarction ; distress questionnaires ; help-seeking behavior ; music listening ; social distance ; worries ; killing time ; obesity ; eating disorder ; obesity surgery ; social dilemma ; fear of infection ; safety measures ; collective behavior ; pathogens ; self-control ; emotions ; optimism ; satisfaction with life ; coping with stress ; behavioral change ; remote work ; exercise ; sustained effects ; government response ; infection rate ; adoption of PARs ; China ; hospital workers ; quality of life ; insomnia ; distance learning ; psycho-emotional impact ; vaccinations ; sentiment analysis ; Twitter ; anti-vax ; vaccine hesitancy ; Python ; VADER ; NLTK ; sleep quality ; mindfulness ; distress ; COVID-19 lockdown ; longitudinal study ; path analysis ; COVID-19 epidemic ; media consumption ; subjective well-being ; safety-seeking behaviors ; information seeking ; television news use ; emotional distress ; social media news use ; health information ; online health information ; information-seeking behavior ; undergraduate students ; psychology ; dentistry ; need for structure ; compensatory control ; social class
    Size 1 electronic resource (490 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021290473
    ISBN 9783036530154 ; 3036530150
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: CD4+ Regulatory T Cells in Human Cancer: Subsets, Origin, and Molecular Regulation.

    Swatler, Julian / De Luca, Marco / Rotella, Ivano / Lise, Veronica / Mazza, Emilia Maria Cristina / Lugli, Enrico

    Cancer immunology research

    2024  Volume 12, Issue 4, Page(s) 393–399

    Abstract: CD4+CD25hiFOXP3+ regulatory T cells (Treg) play major roles in the maintenance of immune tolerance, prevention of inflammation, and tissue homeostasis and repair. In contrast with these beneficial roles, Tregs are abundant in virtually all tumors and ... ...

    Abstract CD4+CD25hiFOXP3+ regulatory T cells (Treg) play major roles in the maintenance of immune tolerance, prevention of inflammation, and tissue homeostasis and repair. In contrast with these beneficial roles, Tregs are abundant in virtually all tumors and have been mechanistically linked to disease progression, metastases development, and therapy resistance. Tregs are thus recognized as a major target for cancer immunotherapy. Compared with other sites in the body, tumors harbor hyperactivated Treg subsets whose molecular characteristics are only beginning to be elucidated. Here, we describe current knowledge of intratumoral Tregs and discuss their potential cellular and tissue origin. Furthermore, we describe currently recognized molecular regulators that drive differentiation and maintenance of Tregs in cancer, with a special focus on those signals regulating their chronic immune activation, with relevant implications for cancer progression and therapy.
    MeSH term(s) Humans ; T-Lymphocytes, Regulatory ; Neoplasms/therapy ; Immune Tolerance ; Immunotherapy ; Inflammation
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2732489-8
    ISSN 2326-6074 ; 2326-6066
    ISSN (online) 2326-6074
    ISSN 2326-6066
    DOI 10.1158/2326-6066.CIR-23-0517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Climate-driven growth dynamics and trend reversal of Fagus sylvatica L. and Quercus cerris L. in a low-elevation beech forest in Central Italy.

    Mazza, Gianluigi / Monteverdi, Maria Cristina / Altieri, Simona / Battipaglia, Giovanna

    The Science of the total environment

    2023  Volume 908, Page(s) 168250

    Abstract: In highly climate-change-sensitive regions, such as the Mediterranean, increasing knowledge of climate-driven growth dynamics is required for habitat conservation and forecasting species adaptability under future climate change. In this study, we test a ... ...

    Abstract In highly climate-change-sensitive regions, such as the Mediterranean, increasing knowledge of climate-driven growth dynamics is required for habitat conservation and forecasting species adaptability under future climate change. In this study, we test a high spectrum of climatic signals, not only monthly and seasonal but also on a multi-year scale and include the single tree analysis to answer this issue, focusing on a low-elevation thermophilic old-growth beech forest surrounding the Bracciano Lake in Central Italy. Through a dendroecological and isotope analysis, we evaluate both short- and long-term sensitivity of F. sylvatica and the coexisting better-drought-adapted species Q. cerris to climatic and hydrological variability in terms of growth reduction and δ
    MeSH term(s) Fagus ; Quercus ; Forests ; Ecosystem ; Italy ; Climate Change ; Droughts
    Language English
    Publishing date 2023-11-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.168250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The ecological validity of the IOP-29: A follow-up study using the MMPI-2-RF and the SIMS as criterion variables.

    Roma, Paolo / Giromini, Luciano / Sellbom, Martin / Cardinale, Alessandra / Ferracuti, Stefano / Mazza, Cristina

    Psychological assessment

    2023  Volume 35, Issue 10, Page(s) 868–879

    Abstract: Current guidelines for conducting symptom validity assessments require that professionals administer multiple symptom validity tests (SVTs) and that the SVTs selected for their evaluations provide nonredundant information. However, not many SVTs are ... ...

    Abstract Current guidelines for conducting symptom validity assessments require that professionals administer multiple symptom validity tests (SVTs) and that the SVTs selected for their evaluations provide nonredundant information. However, not many SVTs are currently available, and most of them rely on the same, (in)frequency-based, feigning detection strategy. In this context, the Inventory of Problems (IOP-29) could be a valuable addition to the assessor's toolbox because of its brevity (29 items) and its different approach to assessing the credibility of presented symptoms. As its ecological validity has been poorly investigated, the present study used a criterion groups design to examine the classification accuracy of the IOP-29 in a data set of 174 court-ordered psychological evaluations focused on psychological injury. The validity scales of the Minnesota Multiphasic Personality Inventory-2 Restructured Form and the total score of the Structured Inventory of Malingered Symptoms were used as criterion variables. Overall, the results of this study confirm that the IOP-29 is an effective measure (1.70 ≤
    MeSH term(s) Humans ; Follow-Up Studies ; MMPI ; Databases, Factual ; Malingering ; Psychological Trauma
    Language English
    Publishing date 2023-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1000939-5
    ISSN 1939-134X ; 1040-3590
    ISSN (online) 1939-134X
    ISSN 1040-3590
    DOI 10.1037/pas0001273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Functional Study of SNCA p.V15A Variant: Further Linking α-Synuclein and Glucocerebrosidase.

    Avenali, Micol / Cerri, Silvia / Palmieri, Ilaria / Ongari, Gerardo / Stiuso, Rita / Buongarzone, Gabriele / Tassorelli, Cristina / Biagini, Tommaso / Valente, Marialuisa / Cereda, Cristina / Mazza, Tommaso / Gana, Simone / Pacchetti, Claudio / Valente, Enza Maria

    Movement disorders : official journal of the Movement Disorder Society

    2024  

    Abstract: Background: SNCA p.V15A was reported in five families. In vitro models showed increased aggregation and seeding activity, mitochondrial damage, and apoptosis. Mutant flies had reduced flying ability and survival.: Objectives: To clinically and ... ...

    Abstract Background: SNCA p.V15A was reported in five families. In vitro models showed increased aggregation and seeding activity, mitochondrial damage, and apoptosis. Mutant flies had reduced flying ability and survival.
    Objectives: To clinically and functionally evaluate SNCA p.V15A in a large Italian family with Parkinson's disease (PD).
    Methods: Genetic diagnosis was reached through next-generation sequencing. Pathogenicity was assessed by molecular dynamics simulation and biochemical studies on peripheral blood mononuclear cells (PBMCs).
    Results: Five siblings carried SNCA p.V15A; three developed bradykinetic-rigid PD in their 50s with rapid motor progression and variable cognitive impairment. A fourth sibling had isolated mood disturbance, whereas the fifth was still unaffected at age 47. The mutant protein showed decreased stability and an unstable folded structure. Proband's PBMCs showed elevated total and phosphorylated α-synuclein (α-syn) levels and significantly reduced glucocerebrosidase activity.
    Conclusion: This study demonstrates accumulation of α-syn
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.29736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Machine learning item selection for short scale construction: A proof-of-concept using the SIMS.

    Orrù, Graziella / De Marchi, Barbara / Sartori, Giuseppe / Gemignani, Angelo / Scarpazza, Cristina / Monaro, Merylin / Mazza, Cristina / Roma, Paolo

    The Clinical neuropsychologist

    2022  Volume 37, Issue 7, Page(s) 1371–1388

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Humans ; Neuropsychological Tests ; Malingering/diagnosis ; Psychometrics ; Surveys and Questionnaires ; Self Report ; Reproducibility of Results
    Language English
    Publishing date 2022-08-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 639080-8
    ISSN 1744-4144 ; 0920-1637 ; 1385-4046
    ISSN (online) 1744-4144
    ISSN 0920-1637 ; 1385-4046
    DOI 10.1080/13854046.2022.2114548
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Urgent Need for More Cardiac Rehabilitation in the Aim to "Preserve" Patients With Heart Failure.

    Leggio, Massimo / Tiberti, Cristina / Villano, Angelo / Fusco, Augusto / Mazza, Andrea

    JACC. Heart failure

    2021  Volume 9, Issue 8, Page(s) 610

    MeSH term(s) Cardiac Rehabilitation ; Exercise Therapy ; Exercise Tolerance ; Heart Failure ; Humans
    Language English
    Publishing date 2021-07-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2021.05.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Higher Seasonal Variation of Systemic Inflammation in Bipolar Disorder.

    Dallaspezia, Sara / Cardaci, Vincenzo / Mazza, Mario Gennaro / De Lorenzo, Rebecca / Rovere Querini, Patrizia / Colombo, Cristina / Benedetti, Francesco

    International journal of molecular sciences

    2024  Volume 25, Issue 8

    Abstract: Seasonal rhythms affect the immune system. Evidence supports the involvement of immuno-inflammatory mechanisms in bipolar disorder (BD), with the neutrophil to lymphocyte ratio (NLR), and the systemic immune-inflammatory index (SII; platelets × ... ...

    Abstract Seasonal rhythms affect the immune system. Evidence supports the involvement of immuno-inflammatory mechanisms in bipolar disorder (BD), with the neutrophil to lymphocyte ratio (NLR), and the systemic immune-inflammatory index (SII; platelets × neutrophils/lymphocytes) consistently reported to be higher in patients with BD than in HC, but seasonal rhythms of innate and adaptive immunity have never been studied. We retrospectively studied NLR and SII in 824 participants divided into three groups: 321 consecutively admitted inpatients affected by a major depressive episode in course of BD, and 255 consecutively admitted inpatients affected by obsessive-compulsive disorder (OCD; positive psychiatric control), and 248 healthy controls (HC). Patients with BD showed markedly higher markers of systemic inflammation in autumn and winter, but not in spring and summer, in respect to both HC and patients with OCD, thus suggesting a specific effect of season on inflammatory markers in BD, independent of a shared hospital setting and drug treatment. Given that systemic inflammation is emerging as a new marker and as target for treatment in depressive disorders, we suggest that seasonal rhythms should be considered for tailoring antidepressant immuno-modulatory treatments in a precision medicine approach.
    MeSH term(s) Humans ; Bipolar Disorder/blood ; Bipolar Disorder/immunology ; Seasons ; Female ; Male ; Inflammation/blood ; Adult ; Middle Aged ; Neutrophils/immunology ; Lymphocytes/immunology ; Lymphocytes/metabolism ; Retrospective Studies ; Biomarkers/blood ; Obsessive-Compulsive Disorder/immunology ; Depressive Disorder, Major/blood ; Depressive Disorder, Major/immunology
    Chemical Substances Biomarkers
    Language English
    Publishing date 2024-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25084310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A precision medicine approach for the primary prevention of cardiovascular events in diabetic patients.

    Leggio, Massimo / Tiberti, Cristina / Mazza, Andrea

    European journal of preventive cardiology

    2019  Volume 26, Issue 16, Page(s) 1781–1782

    MeSH term(s) Aspirin ; Cardiovascular Diseases ; Cardiovascular System ; Diabetes Mellitus ; Humans ; Precision Medicine ; Primary Prevention
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2019-04-11
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1177/2047487319843058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cardiorespiratory Fitness in Healthy People: A Step Forward to Primary Cardiovascular Health Promotion.

    Leggio, Massimo / Tiberti, Cristina / Limongelli, Giorgio / Mazza, Andrea

    The American journal of medicine

    2019  Volume 132, Issue 5, Page(s) e564

    MeSH term(s) Blood Pressure ; Blood Pressure Determination ; Cardiorespiratory Fitness ; Health Promotion ; Physical Fitness ; Risk Factors
    Language English
    Publishing date 2019-01-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2018.12.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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