LIVIVO - Search results -

Search results

Result 1 - 10 of total 39

Search options

Article: Epidemiological characteristics of

Zhu, Jiaying / Ju, Yanmin / Zhou, Xinyu / Chen, Taoyu / Zhuge, Xiangkai / Dai, Jianjun

2023 Volume 14, Page(s) 1219733

Abstract: Carbapenem- ... ...

Abstract	Carbapenem-resistant
Language	English
Publishing date	2023-07-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1219733
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling.

Wang, Zhongxing / Zhu, Dongyu / Zhang, Yuting / Xia, Fufang / Zhu, Jiaying / Dai, Jianjun / Zhuge, Xiangkai

Microbial cell factories

2023 Volume 22, Issue 1, Page(s) 177

Abstract: Background: Avian pathogenic Escherichia coli (APEC) is the major pathogen causing important avian diseases in poultry. As an important subtype of extraintestinal pathogenic E. coli, APEC has zoonotic potential and is considered a foodborne pathogen. ... ...

Abstract	Background: Avian pathogenic Escherichia coli (APEC) is the major pathogen causing important avian diseases in poultry. As an important subtype of extraintestinal pathogenic E. coli, APEC has zoonotic potential and is considered a foodborne pathogen. APEC extracellular vesicles (EVs) may play vital roles in the interaction of the pathogen with its host cells. However, the precise roles played by APEC EVs are still not completely clear, especially in immune cells. Results: In this study, we investigated the relationships between APEC EVs and immune cells. The production and characteristics of the EVs of APEC isolate CT265 were identified. Toll like receptor 4 (TLR4) triggered the cellular immune responses when it interacted with APEC EVs. APEC EVs induced a significant release of proinflammatory cytokines in THP-1 macrophages. APEC EVs induced the macrophage inflammatory response via the TLR4/MYD88/NF-κB signaling pathway, which participated in the activation of the APEC-EV-induced NLRP3 inflammasome. However, the loss of lipopolysaccharide (LPS) from APEC EVs reduced the activation of the NLRP3 inflammasome mediated by TLR4/MYD88/NF-κB signaling. Because APEC EVs activated the macrophage inflammatory response and cytokines release, we speculated that the interaction between APEC EVs and macrophages activated and promoted neutrophil migration during APEC extraintestinal infection. This study is the first to report that APEC EVs induce the formation of neutrophil extracellular traps (NETs) and chicken heterophil extracellular traps. Treatment with APEC EVs induced SAPK/JNK activation in neutrophils. The inhibition of TLR4 signaling suppressed APEC-EV-induced NET formation. However, although APEC EVs activated the immune response of macrophages and initiated NET formation, they also damaged macrophages, causing their apoptosis. The loss of LPS from APEC EVs did not prevent this process. Conclusion: APEC-derived EVs induced inflammatory responses in macrophages and NETs in neutrophils, and that TLR4 was involved in the APEC-EV-activated inflammatory response. These findings provided a basis for the further study of APEC pathogenesis.
MeSH term(s)	Humans ; Extracellular Traps ; Escherichia coli ; Toll-Like Receptor 4 ; NF-kappa B ; Inflammasomes ; Lipopolysaccharides ; Myeloid Differentiation Factor 88 ; NLR Family, Pyrin Domain-Containing 3 Protein ; Signal Transduction ; Extracellular Vesicles ; Adaptor Proteins, Signal Transducing ; Escherichia coli Infections/veterinary
Chemical Substances	Toll-Like Receptor 4 ; NF-kappa B ; Inflammasomes ; Lipopolysaccharides ; Myeloid Differentiation Factor 88 ; NLR Family, Pyrin Domain-Containing 3 Protein ; Adaptor Proteins, Signal Transducing ; TLR4 protein, human
Language	English
Publishing date	2023-09-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2091377-1
ISSN	1475-2859 ; 1475-2859
ISSN (online)	1475-2859
ISSN	1475-2859
DOI	10.1186/s12934-023-02171-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Genomics Analysis to Identify Multiple Genetic Determinants That Drive the Global Transmission of the Pandemic ST95 Lineage of Extraintestinal Pathogenic

Xia, Fufang / Cheng, Jinlong / Jiang, Min / Wang, Zhongxing / Wen, Zhe / Wang, Min / Ren, Jianluan / Zhuge, Xiangkai

Pathogens (Basel, Switzerland)

2022 Volume 11, Issue 12

Abstract: Extraintestinal ... ...

Abstract	Extraintestinal pathogenic
Language	English
Publishing date	2022-12-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens11121489
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A Potential Nontraditional Approach To Combat

Wang, Xiaoming / Liu, Ting / Lv, Xi / Sun, Naiyan / Li, Fan / Luo, Lei / Zhuge, Xiangkai / Huang, Jinhu / Wang, Liping

Antimicrobial agents and chemotherapy

2023 Volume 67, Issue 7, Page(s) e0004723

Abstract: The emergence of TMexCD1-TOprJ1, a novel transferable resistance-nodulation-division (RND)-type efflux pump conferring resistance to tigecycline, is now a serious public health issue in the world. Here, we found that melatonin synergistically enhanced ... ...

Abstract	The emergence of TMexCD1-TOprJ1, a novel transferable resistance-nodulation-division (RND)-type efflux pump conferring resistance to tigecycline, is now a serious public health issue in the world. Here, we found that melatonin synergistically enhanced the antibacterial efficacy of tigecycline against
MeSH term(s)	Animals ; Mice ; Tigecycline/pharmacology ; Melatonin/pharmacology ; Melatonin/metabolism ; Minocycline/pharmacology ; Klebsiella Infections/drug therapy ; Klebsiella Infections/microbiology ; Drug Resistance, Bacterial/genetics ; Membrane Transport Proteins/genetics ; Anti-Bacterial Agents/therapeutic use ; Adjuvants, Immunologic ; Adjuvants, Pharmaceutic ; Microbial Sensitivity Tests ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/metabolism
Chemical Substances	Tigecycline (70JE2N95KR) ; Melatonin (JL5DK93RCL) ; Minocycline (FYY3R43WGO) ; Membrane Transport Proteins ; Anti-Bacterial Agents ; Adjuvants, Immunologic ; Adjuvants, Pharmaceutic
Language	English
Publishing date	2023-06-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	217602-6
ISSN	1098-6596 ; 0066-4804
ISSN (online)	1098-6596
ISSN	0066-4804
DOI	10.1128/aac.00047-23
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 809: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Einzelsignatur: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: ProQ binding to small RNA RyfA promotes virulence and biofilm formation in avian pathogenic Escherichia coli.

Wang, Zhongxing / Chen, Rui / Xia, Fufang / Jiang, Min / Zhu, Dongyu / Zhang, Yuting / Dai, Jianjun / Zhuge, Xiangkai

Veterinary research

2023 Volume 54, Issue 1, Page(s) 109

Abstract: Avian pathogenic Escherichia coli (APEC) is a notable subpathotype of the nonhuman extraintestinal pathogenic E. coli (ExPEC). Recognized as an extraintestinal foodborne pathogen, the zoonotic potential of APEC/ExPEC allows for cross-host transmission ... ...

Abstract	Avian pathogenic Escherichia coli (APEC) is a notable subpathotype of the nonhuman extraintestinal pathogenic E. coli (ExPEC). Recognized as an extraintestinal foodborne pathogen, the zoonotic potential of APEC/ExPEC allows for cross-host transmission via APEC-contaminated poultry meat and eggs. ProQ, an RNA binding protein, is evolutionarily conserved in E. coli. However, its regulatory roles in the biofilm formation and virulence of APEC/ExPEC have not been explored. In this study, proQ deletion in the APEC strain FY26 significantly compromised its biofilm-forming ability. Furthermore, animal tests and cellular infection experiments showed that ProQ depletion significantly attenuated APEC virulence, thereby diminishing its capacity for bloodstream infection and effective adherence to and persistence within host cells. Transcriptome analysis revealed a decrease in the transcription level of the small RNA (sRNA) RyfA in the mutant FY26ΔproQ, suggesting a direct interaction between the sRNA RyfA and ProQ. This interaction might indicate that sRNA RyfA is a novel ProQ-associated sRNA. Moreover, the direct binding of ProQ to the sRNA RyfA was crucial for APEC biofilm formation, pathogenicity, adhesion, and intracellular survival. In conclusion, our findings provide detailed insight into the interaction between ProQ and sRNA RyfA and deepen our understanding of the regulatory elements that dictate APEC virulence and biofilm development. Such insights are instrumental in developing strategies to counteract APEC colonization within hosts and impede APEC biofilm establishment on food surfaces.
MeSH term(s)	Animals ; Escherichia coli ; Virulence ; Escherichia coli Infections/veterinary ; Chickens/genetics ; Poultry Diseases/pathology ; Virulence Factors/genetics ; Biofilms ; RNA, Small Untranslated ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; RNA-Binding Proteins
Chemical Substances	Virulence Factors ; RNA, Small Untranslated ; Escherichia coli Proteins ; ProQ protein, E coli ; RNA-Binding Proteins
Language	English
Publishing date	2023-11-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1146298-x
ISSN	1297-9716 ; 0928-4249
ISSN (online)	1297-9716
ISSN	0928-4249
DOI	10.1186/s13567-023-01241-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1313: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Dissemination of virulence and resistance genes among Klebsiella pneumoniae via outer membrane vesicle: An important plasmid transfer mechanism to promote the emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae.

Wang, Zhongxing / Wen, Zhe / Jiang, Min / Xia, Fufang / Wang, Min / Zhuge, Xiangkai / Dai, Jianjun

Transboundary and emerging diseases

2022 Volume 69, Issue 5, Page(s) e2661–e2676

Abstract: Klebsiella pneumoniae is well-known opportunistic enterobacteria involved in complex clinical infections in humans and animals. The domestic animals might be a source of the multidrug-resistant virulent K. pneumoniae to humans. K. pneumoniae infections ... ...

Abstract	Klebsiella pneumoniae is well-known opportunistic enterobacteria involved in complex clinical infections in humans and animals. The domestic animals might be a source of the multidrug-resistant virulent K. pneumoniae to humans. K. pneumoniae infections in domestic animals are considered as an emergent global concern. The horizontal gene transfer plays essential roles in bacterial genome evolution by spread of virulence and resistance determinants. However, the virulence genes can be transferred horizontally via K. pneumoniae-derived outer membrane vesicles (OMVs) remains to be unreported. In this study, we performed complete genome sequencing of two K. pneumoniae HvK2115 and CRK3022 with hypervirulent or carbapenem-resistant traits. OMVs from K. pneumoniae HvK2115 and CRK3022 were purified and observed. The carriage of virulence or resistance genes in K. pneumoniae OMVs was identified. The influence of OMVs on the horizontal transfer of virulence-related or drug-resistant plasmids among K. pneumoniae strains was evaluated thoroughly. The plasmid transfer to recipient bacteria through OMVs was identified by polymerase chain reaction, pulsed field gel electrophoresis and Southern blot. This study revealed that OMVs could mediate the intraspecific and interspecific horizontal transfer of the virulence plasmid phvK2115. OMVs could simultaneously transfer two resistance plasmids into K. pneumoniae and Escherichia coli recipient strains. OMVs-mediated horizontal transfer of virulence plasmid phvK2115 could significantly enhance the pathogenicity of human carbapenem-resistant K. pneumoniae CRK3022. The CRK3022 acquired the virulence plasmid phvK2115 could become a CR-hvKp strain. It was critically important that OMVs-mediated horizontal transfer of phvK2115 lead to the coexistence of virulence and carbapenem-resistance genes in K. pneumoniae, resulting in the emerging of carbapenem-resistant hypervirulent K. pneumoniae.
MeSH term(s)	Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Carbapenem-Resistant Enterobacteriaceae ; Carbapenems/pharmacology ; Escherichia coli/genetics ; Humans ; Klebsiella Infections/microbiology ; Klebsiella Infections/veterinary ; Klebsiella pneumoniae/genetics ; Plasmids/genetics ; Virulence/genetics ; beta-Lactamases
Chemical Substances	Anti-Bacterial Agents ; Carbapenems ; beta-Lactamases (EC 3.5.2.6)
Language	English
Publishing date	2022-06-25
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2414822-2
ISSN	1865-1682 ; 1865-1674
ISSN (online)	1865-1682
ISSN	1865-1674
DOI	10.1111/tbed.14615
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Dissemination of virulence and resistance genes among Klebsiella pneumoniae via outer membrane vesicle: An important plasmid transfer mechanism to promote the emergence of carbapenem‐resistant hypervirulent Klebsiella pneumoniae

Wang, Zhongxing / Wen, Zhe / Jiang, Min / Xia, Fufang / Wang, Min / Zhuge, Xiangkai / Dai, Jianjun

Transboundary and emerging diseases. 2022 Sept., v. 69, no. 5

2022

Abstract: Klebsiella pneumoniae is well‐known opportunistic enterobacteria involved in complex clinical infections in humans and animals. The domestic animals might be a source of the multidrug‐resistant virulent K. pneumoniae to humans. K. pneumoniae infections ... ...

Abstract	Klebsiella pneumoniae is well‐known opportunistic enterobacteria involved in complex clinical infections in humans and animals. The domestic animals might be a source of the multidrug‐resistant virulent K. pneumoniae to humans. K. pneumoniae infections in domestic animals are considered as an emergent global concern. The horizontal gene transfer plays essential roles in bacterial genome evolution by spread of virulence and resistance determinants. However, the virulence genes can be transferred horizontally via K. pneumoniae‐derived outer membrane vesicles (OMVs) remains to be unreported. In this study, we performed complete genome sequencing of two K. pneumoniae HvK2115 and CRK3022 with hypervirulent or carbapenem‐resistant traits. OMVs from K. pneumoniae HvK2115 and CRK3022 were purified and observed. The carriage of virulence or resistance genes in K. pneumoniae OMVs was identified. The influence of OMVs on the horizontal transfer of virulence‐related or drug‐resistant plasmids among K. pneumoniae strains was evaluated thoroughly. The plasmid transfer to recipient bacteria through OMVs was identified by polymerase chain reaction, pulsed field gel electrophoresis and Southern blot. This study revealed that OMVs could mediate the intraspecific and interspecific horizontal transfer of the virulence plasmid phvK2115. OMVs could simultaneously transfer two resistance plasmids into K. pneumoniae and Escherichia coli recipient strains. OMVs‐mediated horizontal transfer of virulence plasmid phvK2115 could significantly enhance the pathogenicity of human carbapenem‐resistant K. pneumoniae CRK3022. The CRK3022 acquired the virulence plasmid phvK2115 could become a CR‐hvKp strain. It was critically important that OMVs‐mediated horizontal transfer of phvK2115 lead to the coexistence of virulence and carbapenem‐resistance genes in K. pneumoniae, resulting in the emerging of carbapenem‐resistant hypervirulent K. pneumoniae.
Keywords	Escherichia coli ; Klebsiella pneumoniae ; Southern blotting ; evolution ; genome ; horizontal gene transfer ; humans ; multiple drug resistance ; plasmids ; polymerase chain reaction ; virulence
Language	English
Dates of publication	2022-09
Size	p. e2661-e2676.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	2414822-2
ISSN	1865-1682 ; 1865-1674
ISSN (online)	1865-1682
ISSN	1865-1674
DOI	10.1111/tbed.14615
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Characterization of antimicrobial resistance in chicken-source phylogroup F Escherichia coli: similar populations and resistance spectrums between E. coli recovered from chicken colibacillosis tissues and retail raw meats in Eastern China.

Wang, Min / Jiang, Min / Wang, Zhongxing / Chen, Rui / Zhuge, Xiangkai / Dai, Jianjun

Poultry science

2021 Volume 100, Issue 9, Page(s) 101370

Abstract: The extended-spectrum cephalosporin resistant E. coli from food animals transferring to community settings of humans causes a serious threat to public health. Unlike phylogroup B2 E. coli strains, the clinical significance of isolates in phylogroup F is ... ...

Abstract	The extended-spectrum cephalosporin resistant E. coli from food animals transferring to community settings of humans causes a serious threat to public health. Unlike phylogroup B2 E. coli strains, the clinical significance of isolates in phylogroup F is not well revealed. Here, we report on a collection (n = 563) of phylogroup F E. coli isolates recovered from chicken colibacillosis tissues and retail raw chicken meat samples in Eastern China. There was an overlapped distribution of MLST types between chicken colibacillosis-origin and meat-source phylogroup F E. coli, including dominant STs (ST648, ST405, ST457, ST393, ST1158, etc). This study further investigated the presence of extended-spectrum β-lactamase (ESBL/pAmpC) producers in these chicken-source phylogroup F E. coli strains. The prevalence of extended-spectrum cephalosporin resistant strains in phylogroup F E. coli from chicken colibacillosis and raw meat separately accounted for 66.1 and 71.2%. The resistance genotypes and plasmid replicon types of chicken-source phylogroup F E. coli isolates were characterized by multiplex PCR. Our results revealed β-lactamase CTX-M, OXA, CMY and TEM genes were widespread in chicken-source phylogroup F E. coli, and blaCTX-M was the most predominant ESBL gene. Moreover, there was a high prevalence of non-lactamase resistance genes in these β-lactam-resistant isolates. The replicons IncB/O/K/Z, IncI1, IncN, IncFIC, IncQ1, IncX4, IncY, and p0111, associated with antibiotic-resistant large plasmids, were widespread in chicken-source phylogroup F E. coli. There was no obvious difference for the populations, resistance spectrums, and resistance genotypes between phylogroup F E. coli from chicken colibacillosis tissues and retail meats. This detail assessment of the population and resistance genotype showed chicken-source phylogroup F E. coli might hold zoonotic risk and contribute the spread of multidrug-resistant E. coli to humans.
MeSH term(s)	Animals ; Anti-Bacterial Agents/pharmacology ; Chickens ; Drug Resistance, Bacterial/genetics ; Escherichia coli/genetics ; Escherichia coli Infections/epidemiology ; Escherichia coli Infections/veterinary ; Meat ; Multilocus Sequence Typing/veterinary
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-06-30
Publishing country	England
Document type	Journal Article
ZDB-ID	242586-5
ISSN	1525-3171 ; 0032-5791
ISSN (online)	1525-3171
ISSN	0032-5791
DOI	10.1016/j.psj.2021.101370
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 853: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Protective Effects of N-Acetylcysteine on Lipopolysaccharide-Induced Respiratory Inflammation and Oxidative Stress.

Chen, Hongbai / Ma, Nana / Song, Xiaokun / Wei, Guozhen / Zhang, Hongzhu / Liu, Jing / Shen, Xiangzhen / Zhuge, Xiangkai / Chang, Guangjun

Antioxidants (Basel, Switzerland)

2022 Volume 11, Issue 5

Abstract: As the leading cause of bovine respiratory disease (BRD), bacterial pneumonia can result in tremendous losses in the herd farming industry worldwide. N-acetylcysteine (NAC), an acetylated precursor of the amino acid L-cysteine, has been reported to have ... ...

Abstract	As the leading cause of bovine respiratory disease (BRD), bacterial pneumonia can result in tremendous losses in the herd farming industry worldwide. N-acetylcysteine (NAC), an acetylated precursor of the amino acid L-cysteine, has been reported to have anti-inflammatory and antioxidant properties. To explore the protective effect and underlying mechanisms of NAC in ALI, we investigated its role in lipopolysaccharide (LPS)-induced bovine embryo tracheal cells (EBTr) and mouse lung injury models. We found that NAC pretreatment attenuated LPS-induced inflammation in EBTr and mouse models. Moreover, LPS suppressed the expression of oxidative-related factors in EBTr and promoted gene expression and the secretion of inflammatory cytokines. Conversely, the pretreatment of NAC alleviated the secretion of inflammatory cytokines and decreased their mRNA levels, maintaining stable levels of antioxidative gene expression. In vivo, NAC helped LPS-induced inflammatory responses and lung injury in ALI mice. The relative protein concentration, total cells, and percentage of neutrophils in BALF; the level of secretion of IL-6, IL-8, TNF-α, and IL-1β; MPO activity; lung injury score; and the expression level of inflammatory-related genes were decreased significantly in the NAC group compared with the LPS group. NAC also ameliorated LPS-induced mRNA level changes in antioxidative genes. In conclusion, our findings suggest that NAC affects the inflammatory and oxidative response, alleviating LPS-induced EBTr inflammation and mouse lung injury, which offers a natural therapeutic strategy for BRD.
Language	English
Publishing date	2022-04-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704216-9
ISSN	2076-3921
ISSN	2076-3921
DOI	10.3390/antiox11050879
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Factor H Is Bound by Outer Membrane-Displayed Carbohydrate Metabolism Enzymes of Extraintestinal Pathogenic

Sun, Yu / Xu, Bin / Zhuge, Xiangkai / Tang, Fang / Wang, Xuhang / Gong, Qianwen / Chen, Rui / Xue, Feng / Dai, Jianjun

Frontiers in cellular and infection microbiology

2021 Volume 10, Page(s) 592906

Abstract: Extraintestinal ... ...

Abstract	Extraintestinal pathogenic
MeSH term(s)	Animals ; Carbohydrate Metabolism ; Complement Factor H ; Escherichia coli Infections ; Escherichia coli Proteins/metabolism ; Extraintestinal Pathogenic Escherichia coli ; Humans ; Virulence
Chemical Substances	Escherichia coli Proteins ; Complement Factor H (80295-65-4)
Language	English
Publishing date	2021-01-25
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2619676-1
ISSN	2235-2988 ; 2235-2988
ISSN (online)	2235-2988
ISSN	2235-2988
DOI	10.3389/fcimb.2020.592906
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito