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Article ; Online: Reply: Descemet-stripping endothelial keratoplasty and flange technique of scleral fixation of intraocular lens: Making it easier and safer.

Cervantes, Lorenzo J

Journal of cataract and refractive surgery

2017 Volume 43, Issue 9, Page(s) 1239

MeSH term(s)	Descemet Stripping Endothelial Keratoplasty ; Lenses, Intraocular ; Sclera
Language	English
Publishing date	2017-10-05
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	632744-8
ISSN	1873-4502 ; 0886-3350
ISSN (online)	1873-4502
ISSN	0886-3350
DOI	10.1016/j.jcrs.2017.08.006
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Article ; Online: Combined double-needle flanged-haptic intrascleral fixation of an intraocular lens and Descemet-stripping endothelial keratoplasty.

Cervantes, Lorenzo J

Journal of cataract and refractive surgery

2017 Volume 43, Issue 5, Page(s) 593–596

Abstract: A slight modification to the Yamane transconjunctival double-needle flanged-haptic technique of intrascleral fixation of an intraocular lens (IOL) shows the technique's usefulness when combined with Descemet-stripping endothelial keratoplasty (DSEK). The ...

Abstract	A slight modification to the Yamane transconjunctival double-needle flanged-haptic technique of intrascleral fixation of an intraocular lens (IOL) shows the technique's usefulness when combined with Descemet-stripping endothelial keratoplasty (DSEK). The modification uses bipolar cautery to create flanges at the tip of the IOL haptics and delays tucking the haptics into the scleral tunnels until DSEK has been completed. Bipolar cautery enables the technique to be used in situations in which disposable low- or high-temperature cautery, as originally described, might not be possible. Delaying the haptic tuck until after the complete air fill of DSEK means the surgeon can be confident of the IOL position at all times. This combined technique can be a viable option for patients with aphakia and endothelial cell dysfunction.
MeSH term(s)	Aphakia/surgery ; Descemet Stripping Endothelial Keratoplasty/methods ; Humans ; Lens Implantation, Intraocular/methods ; Lenses, Intraocular ; Needles ; Sclera/surgery
Language	English
Publishing date	2017-06-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	632744-8
ISSN	1873-4502 ; 0886-3350
ISSN (online)	1873-4502
ISSN	0886-3350
DOI	10.1016/j.jcrs.2017.04.025
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Article ; Online: A Novel Virtual Wet Lab-Using a Smartphone Camera Adapter and a Video Conference Platform to Provide Real-Time Surgical Instruction.

Cervantes, Lorenzo J / Tallo, Christian A / Lopes, Caithlin A / Hellier, Erik A / Chu, David S

Cornea

2021 Volume 40, Issue 12, Page(s) 1639–1643

Abstract: Purpose: Proctored surgical instruction has traditionally been taught through in-person interactions in either the operating room or an improvised wet lab. Because of the COVID-19 pandemic, live in-person instruction was not feasible owing to social ... ...

Abstract	Purpose: Proctored surgical instruction has traditionally been taught through in-person interactions in either the operating room or an improvised wet lab. Because of the COVID-19 pandemic, live in-person instruction was not feasible owing to social distancing protocols, so a virtual wet lab (VWL) was proposed and implemented. The purpose of this article is to describe our experience with a VWL as a Descemet membrane endothelial keratoplasty (DMEK) skills-transfer course. This is the first time that a VWL environment has been described for the instruction of ophthalmic surgery. Methods: Thirteen participant surgeons took part in VWLs designed for DMEK skills transfer in September and October 2020. A smartphone camera adapter and a video conference software platform were the unique media for the VWL. After a didactic session, participants were divided into breakout rooms where their surgical scope view was broadcast live, allowing instructors to virtually proctor their participants in real time. Participants were surveyed to assess their satisfaction with the course. Results: All (100%) participants successfully injected and unfolded their DMEK grafts. Ten of the 13 participants completed the survey. Respondents rated the experience highly favorably. Conclusions: With the use of readily available technology, VWLs can be successfully implemented in lieu of in-person skills-transfer courses. Further development catering to the needs of the participant might allow VWLs to serve as a viable option of surgical education, currently limited by geographical and social distancing boundaries.
MeSH term(s)	COVID-19/epidemiology ; Computer Systems ; Descemet Stripping Endothelial Keratoplasty/education ; Humans ; Ophthalmologists/education ; Photography/instrumentation ; SARS-CoV-2 ; Smartphone/instrumentation ; Software ; Surveys and Questionnaires ; User-Computer Interface ; Video-Assisted Surgery/education ; Videoconferencing/instrumentation
Language	English
Publishing date	2021-06-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	604826-2
ISSN	1536-4798 ; 0277-3740
ISSN (online)	1536-4798
ISSN	0277-3740
DOI	10.1097/ICO.0000000000002763
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Zs.A 1790: Show issues

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Article ; Online: Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis.

Cervantes, Lorenzo J / Mah, Francis S

Clinical ophthalmology (Auckland, N.Z.)

2011 Volume 5, Page(s) 495–502

Abstract: Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the ...

Abstract	Bacterial conjunctivitis is a common infectious disease of the eye, characterized by conjunctival hyperemia, eyelid edema, and purulent discharge. Although the prevalence and incidence are not well reported, bacterial conjunctivitis represents one of the most frequent causes of patient visits to both primary care physicians and ophthalmologists. Most cases of nongonococcal and nonchlamydial bacterial conjunctivitis are self-limiting and may resolve without intervention. There is a place for treatment, however, which allows for a shorter time to clinical and microbiological resolution which may decrease the mild morbidity, decrease health care costs of visits and potential complications, return patients back to school or the work force, and limit the potential spread of this communicable infection. Gatifloxacin ophthalmic solution is a broad spectrum 8-methoxyfluroroquinolone bactericidal antibiotic, with good activity against Staphylococcus aureus, Streptococcus species, and Gram-negative pathogens. It also has a relatively good resistance profile, making it a more than adequate choice in the treatment of bacterial conjunctivitis when therapy is warranted.
Language	English
Publishing date	2011-04-18
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2415713-2
ISSN	1177-5483 ; 1177-5483
ISSN (online)	1177-5483
ISSN	1177-5483
DOI	10.2147/OPTH.S13778
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Article ; Online: The dietary protein content slightly affects the body temperature of growing pigs exposed to heat stress.

Morales, Adriana / Valle, J Alan / Castillo, Gilberto / Antoine, Duckens / Avelar, Ernesto / Camacho, Reyna L / Buenabad, Lorenzo / Cervantes, Miguel

Translational animal science

2019 Volume 3, Issue 4, Page(s) 1326–1334

Abstract: Heat stress (HS) increases body temperature (BT) and reduces feed intake in pigs. Increasing the dietary protein content may correct the reduced amino acid intake provoked by HS, but it may further increase BT. The effect of dietary protein level on BT ... ...

Abstract	Heat stress (HS) increases body temperature (BT) and reduces feed intake in pigs. Increasing the dietary protein content may correct the reduced amino acid intake provoked by HS, but it may further increase BT. The effect of dietary protein level on BT of HS pigs was analyzed with nine ileal cannulated pigs (61.7 ± 2.5 kg body weight). A thermometer set to register BT at 5-min intervals was implanted into the ileum. There were two treatments: low-protein (10.8%) wheat-free-amino acid diet (LP); high-protein (21.6%), wheat-soybean-meal diet (HP). The study was conducted in two 10-d periods; in each period, d1 to d6 was for diet adaptation, d7 to d9 was for data analysis, and d10 for ileal sample collection. Pigs were fed at 0600 h (morning), 1400 h (midday), and 2200 h (evening), same amount each time. Following, the separate contribution of ambient temperature and thermal effect of feeding on the postprandial BT increment was analyzed in fed and fasted pigs. Ambient temperature ranged from 30.1 to 35.4 °C and relative humidity from 50% to 84%. Both ambient temperature and BT followed similar patterns. The BT of HP pigs after the morning and midday meals was higher (
Language	English
Publishing date	2019-08-27
Publishing country	England
Document type	Journal Article
ISSN	2573-2102
ISSN (online)	2573-2102
DOI	10.1093/tas/txz143
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Article: A rapid spread of the stony coral tissue loss disease outbreak in the Mexican Caribbean.

Alvarez-Filip, Lorenzo / Estrada-Saldívar, Nuria / Pérez-Cervantes, Esmeralda / Molina-Hernández, Ana / González-Barrios, Francisco J

PeerJ

2019 Volume 7, Page(s) e8069

Abstract: Caribbean reef corals have experienced unprecedented declines from climate change, anthropogenic stressors and infectious diseases in recent decades. Since 2014, a highly lethal, new disease, called stony coral tissue loss disease, has impacted many reef- ...

Abstract	Caribbean reef corals have experienced unprecedented declines from climate change, anthropogenic stressors and infectious diseases in recent decades. Since 2014, a highly lethal, new disease, called stony coral tissue loss disease, has impacted many reef-coral species in Florida. During the summer of 2018, we noticed an anomalously high disease prevalence affecting different coral species in the northern portion of the Mexican Caribbean. We assessed the severity of this outbreak in 2018/2019 using the AGRRA coral protocol to survey 82 reef sites across the Mexican Caribbean. Then, using a subset of 14 sites, we detailed information from before the outbreak (2016/2017) to explore the consequences of the disease on the condition and composition of coral communities. Our findings show that the disease outbreak has already spread across the entire region by affecting similar species (with similar disease patterns) to those previously described for Florida. However, we observed a great variability in prevalence and tissue mortality that was not attributable to any geographical gradient. Using long-term data, we determined that there is no evidence of such high coral disease prevalence anywhere in the region before 2018, which suggests that the entire Mexican Caribbean was afflicted by the disease within a few months. The analysis of sites that contained pre-outbreak information showed that this event considerably increased coral mortality and severely changed the structure of coral communities in the region. Given the high prevalence and lethality of this disease, and the high number of susceptible species, we encourage reef researchers, managers and stakeholders across the Western Atlantic to accord it the highest priority for the near future.
Language	English
Publishing date	2019-11-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2703241-3
ISSN	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.8069
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Article ; Online: Reposicionamiento del anticuerpo monoclonal humanizado anti-CD6 itolizumab en el tratamiento de pacientes con COVID-19

Tania Crombet Ramos / Mayra Ramos Suzarte / Danay Saavedra Hernández / Kalet León Monzón / Julio Betancourt Cervantes / Lázaro Filgueira Morilla / Carlos J. Hidalgo Mesa / Yayquier Díaz Morales / Zaima Mazorra Herrera / Patricia Lorenzo Luaces / Carmen Valenzuela Silva / Geydi Lorenzo Monteagudo / Meyán Cepeda Portales / Armando Caballero López

Anales de la Academia de Ciencias de Cuba, Vol 11, Iss

2021 Volume 3

Abstract: Introducción: La neumonía COVID-19 puede conducir a un estado hiperinflamatorio. El CD6 es una glicoproteína expresada en linfocitos T maduros que constituye un regulador crucial de la activación de las células T. El itolizumab es un anticuerpo ... ...

Abstract	Introducción: La neumonía COVID-19 puede conducir a un estado hiperinflamatorio. El CD6 es una glicoproteína expresada en linfocitos T maduros que constituye un regulador crucial de la activación de las células T. El itolizumab es un anticuerpo monoclonal que reconoce el CD6. Los datos clínicos en enfermedades autoinmunes indican que reduce múltiples citocinas proinflamatorias. Objetivo: evaluar la seguridad y el impacto de itolizumab sobre la interleucina-6, la función pulmonar y la mortalidad de los pacientes con COVID-19. Métodos: Se incluyeron 68 pacientes moderados, severos y críticos en un ensayo de acceso expandido en Cuba. El itolizumab se administró junto con otras terapias incluidas en el protocolo nacional para el SARS-CoV-2. Resultados: Todos los pacientes completaron la primera infusión y 41, recibieron 2 dosis. La mediana de edad fue de 68 años y el 94 % era portador de comorbilidades. El itolizumab mejoró la función pulmonar y fue bien tolerado; 3 sujetos tuvieron eventos adversos graves relacionados. La interleucina-6 disminuyó en individuos con niveles altos y no se incrementó en aquellos pacientes con concentraciones más bajas. La tasa de letalidad a los 14 días fue del 4 % y del 18 % para los pacientes moderados y graves. Aunque este estudio no fue aleatorizado, los datos preliminares sugieren que itolizumab redujo la probabilidad de muerte en comparación con los controles. El tiempo de tratamiento, las manifestaciones neurológicas y los biomarcadores como la razón entre neutrófilos y linfocitos, recuento de neutrófilos y la interleucina-6 se asociaron significativamente con mayor letalidad. Conclusiones. El itolizumab puede interrumpir la cascada inflamatoria y prevenir la morbilidad y mortalidad asociada al COVID-19.
Keywords	itolizumab ; covid-19 ; sars-cov-2 ; síndrome de liberación de citocinas ; cd6 ; anticuerpo monoclonal ; Science ; Q ; Science (General) ; Q1-390
Language	Spanish
Publishing date	2021-09-01T00:00:00Z
Publisher	Academia de Ciencias de Cuba
Document type	Article ; Online
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Article ; Online: A rapid spread of the stony coral tissue loss disease outbreak in the Mexican Caribbean

Lorenzo Alvarez-Filip / Nuria Estrada-Saldívar / Esmeralda Pérez-Cervantes / Ana Molina-Hernández / Francisco J. González-Barrios

PeerJ, Vol 7, p e

2019 Volume 8069

Abstract	Caribbean reef corals have experienced unprecedented declines from climate change, anthropogenic stressors and infectious diseases in recent decades. Since 2014, a highly lethal, new disease, called stony coral tissue loss disease, has impacted many reef-coral species in Florida. During the summer of 2018, we noticed an anomalously high disease prevalence affecting different coral species in the northern portion of the Mexican Caribbean. We assessed the severity of this outbreak in 2018/2019 using the AGRRA coral protocol to survey 82 reef sites across the Mexican Caribbean. Then, using a subset of 14 sites, we detailed information from before the outbreak (2016/2017) to explore the consequences of the disease on the condition and composition of coral communities. Our findings show that the disease outbreak has already spread across the entire region by affecting similar species (with similar disease patterns) to those previously described for Florida. However, we observed a great variability in prevalence and tissue mortality that was not attributable to any geographical gradient. Using long-term data, we determined that there is no evidence of such high coral disease prevalence anywhere in the region before 2018, which suggests that the entire Mexican Caribbean was afflicted by the disease within a few months. The analysis of sites that contained pre-outbreak information showed that this event considerably increased coral mortality and severely changed the structure of coral communities in the region. Given the high prevalence and lethality of this disease, and the high number of susceptible species, we encourage reef researchers, managers and stakeholders across the Western Atlantic to accord it the highest priority for the near future.
Keywords	White plague ; Coral mortality ; Disease prevalence ; Reef monitoring ; Long-term data ; Reef functioning ; White syndrome ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	590 ; 610
Language	English
Publishing date	2019-11-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Pediatric Porcelain Aorta Secondary to Gaucher Disease Type 3C With Successful Aortic Replacement Surgery.

Silva-Estrada, Jorge / Cervantes-Barragán, David E / Reyes-de la Cruz, Lorenzo / Meléndez-Ramírez, Gabriela / Meave, Aloha / Alaez-Verson, Carmen

JACC. Case reports

2022 Volume 4, Issue 22, Page(s) 1504–1508

Abstract: Gaucher type 3C disease with porcelain aorta can cause severe hemodynamic impairment. We report the first case, to our knowledge, of a 13-year-old Mexican girl with ... ...

Abstract	Gaucher type 3C disease with porcelain aorta can cause severe hemodynamic impairment. We report the first case, to our knowledge, of a 13-year-old Mexican girl with a
Language	English
Publishing date	2022-11-16
Publishing country	Netherlands
Document type	Case Reports
ISSN	2666-0849
ISSN (online)	2666-0849
DOI	10.1016/j.jaccas.2022.08.020
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Article ; Online: Taming the terminological tempest in invasion science.

Soto, Ismael / Balzani, Paride / Carneiro, Laís / Cuthbert, Ross N / Macêdo, Rafael / Serhan Tarkan, Ali / Ahmed, Danish A / Bang, Alok / Bacela-Spychalska, Karolina / Bailey, Sarah A / Baudry, Thomas / Ballesteros-Mejia, Liliana / Bortolus, Alejandro / Briski, Elizabeta / Britton, J Robert / Buřič, Miloš / Camacho-Cervantes, Morelia / Cano-Barbacil, Carlos / Copilaș-Ciocianu, Denis /

Coughlan, Neil E / Courtois, Pierre / Csabai, Zoltán / Dalu, Tatenda / De Santis, Vanessa / Dickey, James W E / Dimarco, Romina D / Falk-Andersson, Jannike / Fernandez, Romina D / Florencio, Margarita / Franco, Ana Clara S / García-Berthou, Emili / Giannetto, Daniela / Glavendekic, Milka M / Grabowski, Michał / Heringer, Gustavo / Herrera, Ileana / Huang, Wei / Kamelamela, Katie L / Kirichenko, Natalia I / Kouba, Antonín / Kourantidou, Melina / Kurtul, Irmak / Laufer, Gabriel / Lipták, Boris / Liu, Chunlong / López-López, Eugenia / Lozano, Vanessa / Mammola, Stefano / Marchini, Agnese / Meshkova, Valentyna / Milardi, Marco / Musolin, Dmitrii L / Nuñez, Martin A / Oficialdegui, Francisco J / Patoka, Jiří / Pattison, Zarah / Pincheira-Donoso, Daniel / Piria, Marina / Probert, Anna F / Rasmussen, Jes Jessen / Renault, David / Ribeiro, Filipe / Rilov, Gil / Robinson, Tamara B / Sanchez, Axel E / Schwindt, Evangelina / South, Josie / Stoett, Peter / Verreycken, Hugo / Vilizzi, Lorenzo / Wang, Yong-Jian / Watari, Yuya / Wehi, Priscilla M / Weiperth, András / Wiberg-Larsen, Peter / Yapıcı, Sercan / Yoğurtçuoğlu, Baran / Zenni, Rafael D / Galil, Bella S / Dick, Jaimie T A / Russell, James C / Ricciardi, Anthony / Simberloff, Daniel / Bradshaw, Corey J A / Haubrock, Phillip J

Biological reviews of the Cambridge Philosophical Society

2024

Abstract: Standardised terminology in science is important for clarity of interpretation and communication. In invasion science - a dynamic and rapidly evolving discipline - the proliferation of technical terminology has lacked a standardised framework for its ... ...

Abstract	Standardised terminology in science is important for clarity of interpretation and communication. In invasion science - a dynamic and rapidly evolving discipline - the proliferation of technical terminology has lacked a standardised framework for its development. The result is a convoluted and inconsistent usage of terminology, with various discrepancies in descriptions of damage and interventions. A standardised framework is therefore needed for a clear, universally applicable, and consistent terminology to promote more effective communication across researchers, stakeholders, and policymakers. Inconsistencies in terminology stem from the exponential increase in scientific publications on the patterns and processes of biological invasions authored by experts from various disciplines and countries since the 1990s, as well as publications by legislators and policymakers focusing on practical applications, regulations, and management of resources. Aligning and standardising terminology across stakeholders remains a challenge in invasion science. Here, we review and evaluate the multiple terms used in invasion science (e.g. 'non-native', 'alien', 'invasive' or 'invader', 'exotic', 'non-indigenous', 'naturalised', 'pest') to propose a more simplified and standardised terminology. The streamlined framework we propose and translate into 28 other languages is based on the terms (i) 'non-native', denoting species transported beyond their natural biogeographic range, (ii) 'established non-native', i.e. those non-native species that have established self-sustaining populations in their new location(s) in the wild, and (iii) 'invasive non-native' - populations of established non-native species that have recently spread or are spreading rapidly in their invaded range actively or passively with or without human mediation. We also highlight the importance of conceptualising 'spread' for classifying invasiveness and 'impact' for management. Finally, we propose a protocol for classifying populations based on (i) dispersal mechanism, (ii) species origin, (iii) population status, and (iv) impact. Collectively and without introducing new terminology, the framework that we present aims to facilitate effective communication and collaboration in invasion science and management of non-native species.
Language	English
Publishing date	2024-03-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1423558-4
ISSN	1469-185X ; 0006-3231 ; 1464-7931
ISSN (online)	1469-185X
ISSN	0006-3231 ; 1464-7931
DOI	10.1111/brv.13071
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