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  1. Article: New indexes for myofibril linearity in muscle image analysis.

    Rocchi, Ettore / Peluso, Sara / Amatori, Stefano / Sisti, Davide

    European journal of translational myology

    2022  

    Abstract: The endeavor to evaluate the linearity of myofibrillar structures and their potential deviation from a straight line is a fascinating problem in muscle tissue image analysis. In this Letter, we suggest two different strategies for solving the same ... ...

    Abstract The endeavor to evaluate the linearity of myofibrillar structures and their potential deviation from a straight line is a fascinating problem in muscle tissue image analysis. In this Letter, we suggest two different strategies for solving the same challenge. The first strategy is based on an alignment index, which could be derived by comparing the sum of the lengths of the individual sarcomeres with the distance between the "head" of the first and the "tail" of the last sarcomere. The second strategy relies on circular statistics, which takes a cue from an already suggested method. Our proposed methods are alternatives: the former has the advantage of simplicity; the latter is certainly more elegant and gives greater substance to statistical analysis, but in contrast, it also has greater computational complexity.
    Language English
    Publishing date 2022-10-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2545577-1
    ISSN 2037-7460 ; 2037-7452
    ISSN (online) 2037-7460
    ISSN 2037-7452
    DOI 10.4081/ejtm.2022.10736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Using Pre- and Posttest Predictive Probabilities to Evaluate Diagnostic Test Is a Confusing Habit.

    Rocchi, Ettore / Peluso, Sara / Sisti, Davide

    Critical care medicine

    2020  Volume 48, Issue 12, Page(s) e1374–e1375

    MeSH term(s) Diagnostic Tests, Routine ; Emergency Service, Hospital ; Habits ; Humans ; Monocytes ; Probability ; Sensitivity and Specificity ; Sepsis
    Language English
    Publishing date 2020-11-27
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004606
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
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  3. Article ; Online: Letter to the Editor Regarding "The Effect of Hippocampal Avoidance Whole Brain Radiotherapy on the Preservation of Long-Term Neurocognitive Function in Non-Small Cell Lung Cancer Patients with Brain Metastasis".

    Pezzulla, Donato / Maurizi, Francesca / Rocchi, Ettore / Peluso, Sara / De Cicco, Luigi / Chiesa, Silvia / di Franco, Rossella

    Technology in cancer research & treatment

    2023  Volume 22, Page(s) 15330338231169599

    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung ; Lung Neoplasms ; Brain Neoplasms/radiotherapy ; Cranial Irradiation ; Hippocampus ; Brain
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Letter
    ZDB-ID 2146365-7
    ISSN 1533-0338 ; 1533-0346
    ISSN (online) 1533-0338
    ISSN 1533-0346
    DOI 10.1177/15330338231169599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5871: Show issues Location:
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  4. Article ; Online: A Possible Scenario for the Covid-19 Epidemic, Based on the SI(R) Model.

    Rocchi, Ettore / Peluso, Sara / Sisti, Davide / Carletti, Margherita

    SN comprehensive clinical medicine

    2020  Volume 2, Issue 5, Page(s) 501–503

    Abstract: Many attempts to build epidemic models of the current Covid-19 epidemic have been made in the recent past. However, only models postulating permanent immunity have been proposed. In this paper, we propose a SI(R) model in order to forecast the evolution ... ...

    Abstract Many attempts to build epidemic models of the current Covid-19 epidemic have been made in the recent past. However, only models postulating permanent immunity have been proposed. In this paper, we propose a SI(R) model in order to forecast the evolution of the epidemic under the hypothesis of not permanent immunity. This model offers an analytical solution to the problem of finding possible steady states, providing the following equilibrium values: Susceptible about 17%, Recovered (including deceased and healed) ranging from 79 to 81%, and Infected ranging from 2 to 4%. However, it is crucial to consider that the results concerning the recovered, which at first glance are particularly impressive, include the huge proportion of asymptomatic subjects. On the basis of these considerations, we analyse the situation in the province of Pesaro-Urbino, one of the main outbreaks of the epidemic in Italy.
    Keywords covid19
    Language English
    Publishing date 2020-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2947211-8
    ISSN 2523-8973 ; 2523-8973
    ISSN (online) 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00306-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Possible Scenario for the Covid-19 Epidemic, Based on the SI(R) Model

    Rocchi, Ettore / Peluso, Sara / Sisti, Davide / Carletti, Margherita

    SN Comprehensive Clinical Medicine

    2020  Volume 2, Issue 5, Page(s) 501–503

    Keywords covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2947211-8
    ISSN 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00306-z
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article ; Online: A Possible Scenario for the Covid-19 Epidemic, Based on the SI(R) Model

    Rocchi, Ettore / Peluso, Sara / Sisti, Davide / Carletti, Margherita

    2020  

    Keywords Covid-19 ; Epidemic model ; SI(R)model ; SIRS model ; covid19
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article ; Online: Comparing Heterologous and Homologous COVID-19 Vaccination: A Longitudinal Study of Antibody Decay.

    Orlandi, Chiara / Stefanetti, Giuseppe / Barocci, Simone / Buffi, Gloria / Diotallevi, Aurora / Rocchi, Ettore / Ceccarelli, Marcello / Peluso, Sara / Vandini, Daniela / Carlotti, Eugenio / Magnani, Mauro / Galluzzi, Luca / Casabianca, Anna

    Viruses

    2023  Volume 15, Issue 5

    Abstract: The humoral response after vaccination was evaluated in 1248 individuals who received different COVID-19 vaccine schedules. The study compared subjects primed with adenoviral ChAdOx1-S (ChAd) and boosted with BNT162b2 (BNT) mRNA vaccines (ChAd/BNT) to ... ...

    Abstract The humoral response after vaccination was evaluated in 1248 individuals who received different COVID-19 vaccine schedules. The study compared subjects primed with adenoviral ChAdOx1-S (ChAd) and boosted with BNT162b2 (BNT) mRNA vaccines (ChAd/BNT) to homologous dosing with BNT/BNT or ChAd/ChAd vaccines. Serum samples were collected at two, four and six months after vaccination, and anti-Spike IgG responses were determined. The heterologous vaccination induced a more robust immune response than the two homologous vaccinations. ChAd/BNT induced a stronger immune response than ChAd/ChAd at all time points, whereas the differences between ChAd/BNT and BNT/BNT decreased over time and were not significant at six months. Furthermore, the kinetic parameters associated with IgG decay were estimated by applying a first-order kinetics equation. ChAd/BNT vaccination was associated with the longest time of anti-S IgG negativization and with a slow decay of the titer over time. Finally, analyzing factors influencing the immune response by ANCOVA analysis, it was found that the vaccine schedule had a significant impact on both the IgG titer and kinetic parameters, and having a Body Mass Index (BMI) above the overweight threshold was associated with an impaired immune response. Overall, the heterologous ChAd/BNT vaccination may offer longer-lasting protection against SARS-CoV-2 than homologous vaccination strategies.
    MeSH term(s) Humans ; COVID-19 Vaccines ; Longitudinal Studies ; BNT162 Vaccine ; COVID-19/prevention & control ; SARS-CoV-2 ; Vaccination ; ChAdOx1 nCoV-19 ; Immunoglobulin G ; Antibodies, Viral ; Antibodies, Neutralizing
    Chemical Substances COVID-19 Vaccines ; BNT162 Vaccine ; ChAdOx1 nCoV-19 (B5S3K2V0G8) ; Immunoglobulin G ; Antibodies, Viral ; Antibodies, Neutralizing
    Language English
    Publishing date 2023-05-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15051162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A Possible Scenario for the Covid-19 Epidemic, Based on the SI(R) Model

    Rocchi, Ettore / Peluso, Sara / Sisti, Davide / Carletti, Margherita

    SN Compr Clin Med

    Abstract: Many attempts to build epidemic models of the current Covid-19 epidemic have been made in the recent past. However, only models postulating permanent immunity have been proposed. In this paper, we propose a SI(R) model in order to forecast the evolution ... ...

    Abstract Many attempts to build epidemic models of the current Covid-19 epidemic have been made in the recent past. However, only models postulating permanent immunity have been proposed. In this paper, we propose a SI(R) model in order to forecast the evolution of the epidemic under the hypothesis of not permanent immunity. This model offers an analytical solution to the problem of finding possible steady states, providing the following equilibrium values: Susceptible about 17%, Recovered (including deceased and healed) ranging from 79 to 81%, and Infected ranging from 2 to 4%. However, it is crucial to consider that the results concerning the recovered, which at first glance are particularly impressive, include the huge proportion of asymptomatic subjects. On the basis of these considerations, we analyse the situation in the province of Pesaro-Urbino, one of the main outbreaks of the epidemic in Italy.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #244928
    Database COVID19

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  9. Article: Molecular cytogenetic characterization of deletions on der(9) in chronic myelocytic leukemia.

    Zagaria, Antonella / Anelli, Luisa / Albano, Francesco / Vicari, Laura / Schiavone, Ettore Mariano / Annunziata, Mario / Pane, Fabrizio / Liso, Vincenzo / Rocchi, Mariano / Specchia, Giorgina

    Cancer genetics and cytogenetics

    2006  Volume 167, Issue 2, Page(s) 97–102

    Abstract: The t(9;22)(q34;q11), generating the Philadelphia chromosome, is found in more than 90% of patients with chronic myelocytic leukemia (CML). Deletions adjacent to the translocation breakpoint on the derivative chromosome 9 have been described by several ... ...

    Abstract The t(9;22)(q34;q11), generating the Philadelphia chromosome, is found in more than 90% of patients with chronic myelocytic leukemia (CML). Deletions adjacent to the translocation breakpoint on the derivative chromosome 9 have been described by several groups. These studies revealed two primary points: (1) genomic microdeletions were concomitant with the t(9;22) rearrangement; and (2) the location of the deleted sequence was centromeric to ABL and telomeric to BCR genes. We report on a detailed molecular cytogenetic characterization of chromosomal rearrangements in two CML patients bearing a complex variant t(9;22) and insertions of chromosome 22 sequences in 9q34. Our study shows that the location of the deleted sequences was downstream of the ABL gene and that genomic microdeletions were concomitant with the ins(9;22)(q34;q11q11) rearrangement.
    MeSH term(s) Adult ; Chromosome Aberrations ; Chromosome Deletion ; Chromosomes, Human, Pair 22/ultrastructure ; Chromosomes, Human, Pair 9/ultrastructure ; Female ; Fusion Proteins, bcr-abl/genetics ; Genes, abl ; Humans ; In Situ Hybridization, Fluorescence ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Male ; Middle Aged ; Philadelphia Chromosome ; Proto-Oncogene Proteins c-bcr/genetics
    Chemical Substances Fusion Proteins, bcr-abl (EC 2.7.10.2) ; Proto-Oncogene Proteins c-bcr (EC 2.7.11.1)
    Language English
    Publishing date 2006-06
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 800806-1
    ISSN 1873-4456 ; 0165-4608
    ISSN (online) 1873-4456
    ISSN 0165-4608
    DOI 10.1016/j.cancergencyto.2006.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1521: Show issues Location:
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