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  1. Article: Rare Presentation of Pseudotumor Cerebri in a Pediatric Patient With Granulomatosis With Polyangiitis.

    Sioufi, Henry J / Makvandi, Shayan / Masoud, Rana / Wu, Xiaoyan / Abdul-Aziz, Rabheh

    Cureus

    2020  Volume 12, Issue 11, Page(s) e11567

    Abstract: We present a case of an 11-year-old female with granulomatosis with polyangiitis (GPA) diagnosed one year prior to presentation, stage III chronic kidney disease (CKD), hypertension (HTN), obstructive sleep apnea (OSA), and chronic anemia who presented ... ...

    Abstract We present a case of an 11-year-old female with granulomatosis with polyangiitis (GPA) diagnosed one year prior to presentation, stage III chronic kidney disease (CKD), hypertension (HTN), obstructive sleep apnea (OSA), and chronic anemia who presented with headache, nausea, vomiting, and diplopia and was found to have idiopathic intracranial hypertension (IIH). IIH was reported in adults with GPA and for our knowledge has not been yet reported in pediatric cases of GPA.
    Language English
    Publishing date 2020-11-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.11567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Rare Presentation of Multi-System Inflammatory Disease in Children Associate With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

    Makvandi, Shayan Alibrahim Omar Abdul-Aziz Rabheh Sallam Mohammad Abdul-Fattah McGreevy Megan

    Cureus

    Abstract: Management of multi-system inflammatory disease in children (MIS-C) remains a challenge due to the evolving nature of the coronavirus disease 2019 (COVID-19) pandemic This article reports a rare presentation of multi-system inflammatory disease in a ... ...

    Abstract Management of multi-system inflammatory disease in children (MIS-C) remains a challenge due to the evolving nature of the coronavirus disease 2019 (COVID-19) pandemic This article reports a rare presentation of multi-system inflammatory disease in a previously healthy 16-month-old male who fully recovered with minimal residual cardiac insufficiency upon discharge Our case is unique due to patient's young age, cardiac findings, and his response to our treatment protocol A multi-disciplinary team in a tertiary center was involved with care
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #895704
    Database COVID19

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  3. Article: A Rare Presentation of Multi-System Inflammatory Disease in Children Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).

    Makvandi, Shayan / Alibrahim, Omar / Abdul-Aziz, Rabheh / Abdul-Fattah Sallam, Mohammad / McGreevy, Megan

    Cureus

    2020  Volume 12, Issue 10, Page(s) e10892

    Abstract: Management of multi-system inflammatory disease in children (MIS-C) remains a challenge due to the evolving nature of the coronavirus disease 2019 (COVID-19) pandemic. This article reports a rare presentation of multi-system inflammatory disease in a ... ...

    Abstract Management of multi-system inflammatory disease in children (MIS-C) remains a challenge due to the evolving nature of the coronavirus disease 2019 (COVID-19) pandemic. This article reports a rare presentation of multi-system inflammatory disease in a previously healthy 16-month-old male who fully recovered with minimal residual cardiac insufficiency upon discharge. Our case is unique due to patient's young age, cardiac findings, and his response to our treatment protocol. A multi-disciplinary team in a tertiary center was involved with care.
    Keywords covid19
    Language English
    Publishing date 2020-10-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.10892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Follow-up and management of serologically active clinically quiescent cases in pediatric systemic lupus erythematosus

    Gabrielle Capone / Caroline Lojacono / Fatma Al-Bayitee / Shayan Makvandi / Teresa Hennon / Brian Wrotniak / Rabheh Abdul-Aziz

    Rheumatology, Vol 59, Iss 4, Pp 244-

    2021  Volume 251

    Keywords systemic lupus erythematosus ; serologically active clinically quiescent ; systemic lupus erythematosus disease activity index 2000 ; Medicine ; R
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Article: Follow-up and management of serologically active clinically quiescent cases in pediatric systemic lupus erythematosus.

    Capone, Gabrielle / Lojacono, Caroline / Al-Bayitee, Fatma / Makvandi, Shayan / Hennon, Teresa / Wrotniak, Brian / Abdul-Aziz, Rabheh

    Reumatologia

    2021  Volume 59, Issue 4, Page(s) 244–251

    Abstract: Objectives: Our aim is to identify the presence of serologically active clinically quiescent (SACQ) episodes in pediatric systemic lupus erythematosus (SLE) patients. We aim to identify serologic biomarkers associated with SACQ episodes and discuss ... ...

    Abstract Objectives: Our aim is to identify the presence of serologically active clinically quiescent (SACQ) episodes in pediatric systemic lupus erythematosus (SLE) patients. We aim to identify serologic biomarkers associated with SACQ episodes and discuss risks and benefits of escalating treatments.
    Material and methods: We evaluated 25 pediatric SLE patients, 13 of whom experienced SACQ episodes. Serologically active clinically quiescent was defined as two consecutive clinic visits without any clinical symptoms or clinical examination findings of a lupus flare with a clinical Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) score of zero, but either elevated anti-ds-DNA antibodies or low complement (C3 and/or C4) levels.
    Results: Among the 13 patients who experienced a SACQ episode, there were a total of 24 episodes, with each patient experiencing 1-4 SACQ episodes. Erythrocyte sedimentation rate (ESR) was the most commonly elevated laboratory marker in a SACQ episode, followed by low hemoglobin levels, and then elevated anti-dsDNA antibodies. Of the 17 episodes treated during a SACQ episode, 15 (88%) did not progress to a clinical flare within six months, while two did. Furthermore, of the 7 patients who were not treated during their SACQ episode, 2 (29%) continued to be SACQ without flare, whereas 5 led to a clinical flare within six months.
    Conclusions: Serologically active clinically quiescent episodes were identified in pediatric SLE patients, suggesting that the presence of SACQ is not limited to adults with SLE. Serologic markers such as increased ESR, hemoglobin, and elevated anti-dsDNA antibodies are preliminarily associated with pediatric SACQ episodes. Treating these SACQ episodes in pediatric SLE patients was less likely to lead to a clinical flare within six months when compared to not treating (
    Language English
    Publishing date 2021-08-13
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 604151-6
    ISSN 0034-6233
    ISSN 0034-6233
    DOI 10.5114/reum.2021.108353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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