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Artikel ; Online: Inverse Saffman-Taylor Experiments with Particles Lead to Capillarity Driven Fingering Instabilities.

Bihi, Ilyesse / Baudoin, Michael / Butler, Jason E / Faille, Christine / Zoueshtiagh, Farzam

2016 Band 117, Heft 3, Seite(n) 34501

Abstract: ... at the interface between the fluids if the capillary number exceeds a critical value. This Saffman-Taylor ...

Abstract	Using air to displace a viscous fluid contained in a Hele-Shaw cell can create a fingering pattern at the interface between the fluids if the capillary number exceeds a critical value. This Saffman-Taylor instability is revisited for the inverse case of a viscous fluid displacing air when partially wettable hydrophilic particles are lying on the walls. Though the inverse case is otherwise stable, the presence of the particles results in a fingering instability at low capillary number. This capillary-driven instability is driven by the integration of particles into the interface which results from the minimization of the interfacial energy. Both axisymmetric and rectangular geometries are considered in order to quantify this phenomenon.
Sprache	Englisch
Erscheinungsdatum	2016-07-15
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.117.034501
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Growing Project BioEYES: A Reflection on 20 Years of Developing and Replicating a K-12 Science Outreach Program.

Shuda, Jamie R / Butler, Valerie G / Nelson, Theresa M / Davidson, Jaqueline M / Taylor, Auset M / Farber, Steven A

Zebrafish

2024 Band 21, Heft 2, Seite(n) 109–118

Abstract: Project BioEYES celebrated 20 years in K12 schools during the 2022-2023 school year. Using live zebrafish ( ...

Abstract	Project BioEYES celebrated 20 years in K12 schools during the 2022-2023 school year. Using live zebrafish (
Mesh-Begriff(e)	Animals ; Humans ; Zebrafish ; Science/education ; Schools ; Students
Sprache	Englisch
Erscheinungsdatum	2024-04-13
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2156020-1
ISSN	1557-8542 ; 1545-8547
ISSN (online)	1557-8542
ISSN	1545-8547
DOI	10.1089/zeb.2023.0059
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Presurgical and Postsurgical MRI Evaluation of Osteochondral Lesions of the Foot and Ankle: A Primer.

Butler, James J / Wingo, Taylor / Kennedy, John G

Foot and ankle clinics

2023 Band 28, Heft 3, Seite(n) 603–617

Abstract: The gold standard diagnostic imaging tool for ankle OCLs is magnetic resonance imaging, which allows precise evaluation of the articular cartilage and assessment of the surrounding soft tissue structures. Post-operative morphologic MRI assessment via ... ...

Abstract	The gold standard diagnostic imaging tool for ankle OCLs is magnetic resonance imaging, which allows precise evaluation of the articular cartilage and assessment of the surrounding soft tissue structures. Post-operative morphologic MRI assessment via MOCART scores provide semi-quantitative analysis of the repair tissue, but mixed evidence exists regarding its association with post-operative outcomes. Post-operative biochemical MRIs allow assessment of the collagen network of the articular cartilage via T2-mapping and T2∗ mapping, and assessment of the articular glycosaminoglycan content via delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), T1rho mapping and sodium imaging.
Mesh-Begriff(e)	Humans ; Ankle/diagnostic imaging ; Ankle/surgery ; Contrast Media ; Cartilage, Articular/diagnostic imaging ; Cartilage, Articular/surgery ; Cartilage, Articular/pathology ; Ankle Joint/diagnostic imaging ; Ankle Joint/surgery ; Magnetic Resonance Imaging/methods
Chemische Substanzen	Contrast Media
Sprache	Englisch
Erscheinungsdatum	2023-06-23
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Review
ZDB-ID	2051688-5
ISSN	1558-1934 ; 1083-7515
ISSN (online)	1558-1934
ISSN	1083-7515
DOI	10.1016/j.fcl.2023.04.010
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The safety and efficacy of methylnaltrexone in pediatric oncology patients: A single center experience.

Koranteng, Lauren / Mauguen, Audrey / Butler, Miriam / Yan, Shirley Qiong / Taylor, Damani

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2023 Band 30, Heft 1, Seite(n) 4–8

Abstract: Introduction: Peripherally acting : Methods: This is a retrospective study of 79 pediatric patients with opioid induced constipation. Patients were administered methylnaltrexone during their inpatient stay. Data on bowel activity after ... ...

Abstract	Introduction: Peripherally acting Methods: This is a retrospective study of 79 pediatric patients with opioid induced constipation. Patients were administered methylnaltrexone during their inpatient stay. Data on bowel activity after methylnaltrexone was obtained from the hospital information system. Results: Out of the 79 patients who received methylnaltrexone, there were seven patients from whom data could not be analyzed. Of the 72 patients whose data was available, 38% ( Conclusion: Methylnaltrexone appears safe in the pediatric population and produces bowel movements in more than a third of pediatric patients. It is a feasible and safe option for opioid induced constipation in pediatric patients.
Mesh-Begriff(e)	Adult ; Humans ; Child ; Analgesics, Opioid/adverse effects ; Opioid-Induced Constipation/drug therapy ; Retrospective Studies ; Constipation/chemically induced ; Constipation/drug therapy ; Narcotic Antagonists/adverse effects ; Neoplasms/drug therapy ; Quaternary Ammonium Compounds ; Naltrexone/analogs & derivatives
Chemische Substanzen	methylnaltrexone (0RK7M7IABE) ; Analgesics, Opioid ; Narcotic Antagonists ; Quaternary Ammonium Compounds ; Naltrexone (5S6W795CQM)
Sprache	Englisch
Erscheinungsdatum	2023-03-22
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552231163540
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Removal of beneficial insertion effects prevent the long-term persistence of transposable elements within simulated asexual populations.

Butler, Christopher L / Bell, Ellen A / Taylor, Martin I

BMC genomics

2021 Band 22, Heft 1, Seite(n) 241

Abstract: Background: Transposable elements are significant components of most organism's genomes, yet the reasons why their abundances vary significantly among species is poorly understood. A recent study has suggested that even in the absence of traditional ... ...

Abstract	Background: Transposable elements are significant components of most organism's genomes, yet the reasons why their abundances vary significantly among species is poorly understood. A recent study has suggested that even in the absence of traditional molecular evolutionary explanations, transposon proliferation may occur through a process known as 'transposon engineering'. However, their model used a fixed beneficial transposon insertion frequency of 20%, which we believe to be unrealistically high. Results: Reducing this beneficial insertion frequency, while keeping all other parameters identical, prevented transposon proliferation. Conclusions: We conclude that the author's original findings are better explained through the action of positive selection rather than 'transposon engineering', with beneficial insertion effects remaining important during transposon proliferation events.
Mesh-Begriff(e)	DNA Transposable Elements ; Evolution, Molecular
Chemische Substanzen	DNA Transposable Elements
Sprache	Englisch
Erscheinungsdatum	2021-04-07
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	1471-2164
ISSN (online)	1471-2164
DOI	10.1186/s12864-021-07569-3
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Experiences of US Clinicians Contending With Health Care Resource Scarcity During the COVID-19 Pandemic, December 2020 to December 2021.

Butler, Catherine R / Wightman, Aaron G / Taylor, Janelle S / Hick, John L / O'Hare, Ann M

JAMA network open

2023 Band 6, Heft 6, Seite(n) e2318810

Abstract: Importance: The second year of the COVID-19 pandemic saw periods of dire health care resource limitations in the US, sometimes prompting official declarations of crisis, but little is known about how these conditions were experienced by frontline ... ...

Abstract	Importance: The second year of the COVID-19 pandemic saw periods of dire health care resource limitations in the US, sometimes prompting official declarations of crisis, but little is known about how these conditions were experienced by frontline clinicians. Objective: To describe the experiences of US clinicians practicing under conditions of extreme resource limitation during the second year of the pandemic. Design, setting, and participants: This qualitative inductive thematic analysis was based on interviews with physicians and nurses providing direct patient care at US health care institutions during the COVID-19 pandemic. Interviews were conducted between December 28, 2020, and December 9, 2021. Exposure: Crisis conditions as reflected by official state declarations and/or media reports. Main outcomes and measures: Clinicians' experiences as obtained through interviews. Results: Interviews with 23 clinicians (21 physicians and 2 nurses) who were practicing in California, Idaho, Minnesota, or Texas were included. Of the 23 total participants, 21 responded to a background survey to assess participant demographics; among these individuals, the mean (SD) age was 49 (7.3) years, 12 (57.1%) were men, and 18 (85.7%) self-identified as White. Three themes emerged in qualitative analysis. The first theme describes isolation. Clinicians had a limited view on what was happening outside their immediate practice setting and perceived a disconnect between official messaging about crisis conditions and their own experience. In the absence of overarching system-level support, responsibility for making challenging decisions about how to adapt practices and allocate resources often fell to frontline clinicians. The second theme describes in-the-moment decision-making. Formal crisis declarations did little to guide how resources were allocated in clinical practice. Clinicians adapted practice by drawing on their clinical judgment but described feeling ill equipped to handle some of the operationally and ethically complex situations that fell to them. The third theme describes waning motivation. As the pandemic persisted, the strong sense of mission, duty, and purpose that had fueled extraordinary efforts earlier in the pandemic was eroded by unsatisfying clinical roles, misalignment between clinicians' own values and institutional goals, more distant relationships with patients, and moral distress. Conclusions and relevance: The findings of this qualitative study suggest that institutional plans to protect frontline clinicians from the responsibility for allocating scarce resources may be unworkable, especially in a state of chronic crisis. Efforts are needed to directly integrate frontline clinicians into institutional emergency responses and support them in ways that reflect the complex and dynamic realities of health care resource limitation.
Mesh-Begriff(e)	Male ; Humans ; Middle Aged ; Female ; COVID-19/epidemiology ; Pandemics ; Physicians ; Health Resources ; Delivery of Health Care
Sprache	Englisch
Erscheinungsdatum	2023-06-01
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2023.18810
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Endocrinology/Primary Care Pharmacy Collaboration vs Endocrinology Care Alone in Patients With Type 2 Diabetes and A1c >9.

Fornwald, Courtney R / Russo-Alvarez, Giavanna / Pantalone, Kevin M / Zeleznikar, Elizabeth / Parker, Marcie / McCorkindale, Nicole / Butler, Robert / Hermiller, Taylor

The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians

2024 Band 40, Heft 2, Seite(n) 78–84

Abstract: Background: ...

Abstract	Background:
Sprache	Englisch
Erscheinungsdatum	2024-01-19
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	54478-4
ISSN	8755-1225
ISSN	8755-1225
DOI	10.1177/87551225231224251
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Low-frequency monitoring for community clozapine initiations: A comparative study relative to standard frequency assessments.

Mizuno, Yuya / Bridglal, Devi L / Coumbe, Jack / McGrath, Hari / Adhikari, Ayush / Butler, Emma / Bonoldi, Ilaria / Taylor, David / Howes, Oliver D

Journal of psychopharmacology (Oxford, England)

2023 Band 37, Heft 6, Seite(n) 627–629

Mesh-Begriff(e)	Clozapine/adverse effects ; Antipsychotic Agents/adverse effects ; Cognition
Chemische Substanzen	Clozapine (J60AR2IKIC) ; Antipsychotic Agents
Sprache	Englisch
Erscheinungsdatum	2023-05-12
Erscheinungsland	United States
Dokumenttyp	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	639313-5
ISSN	1461-7285 ; 0269-8811
ISSN (online)	1461-7285
ISSN	0269-8811
DOI	10.1177/02698811231171532
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Effects of Parent-Implemented Interventions on Outcomes of Children with Autism: A Meta-Analysis.

Cheng, Wai Man / Smith, Timothy B / Butler, Marshall / Taylor, Tina M / Clayton, Devan

Journal of autism and developmental disorders

2022 Band 53, Heft 11, Seite(n) 4147–4163

Abstract: Children with autism spectrum disorder (ASD) have been shown to benefit from parent-implemented interventions (PIIs). This meta-analysis improved on prior reviews of PIIs by evaluating RCTs and multiple potential moderators, including indicators of ... ...

Abstract	Children with autism spectrum disorder (ASD) have been shown to benefit from parent-implemented interventions (PIIs). This meta-analysis improved on prior reviews of PIIs by evaluating RCTs and multiple potential moderators, including indicators of research quality. Fifty-one effect sizes averaged moderately strong overall benefits of PIIs (g = 0.553), with studies having lower risk of research bias yielding lower estimates (g = 0.47). Parent and observer ratings yielded similar averaged estimates for positive behavior/social skills (g = 0.603), language/communication (g = 0.545), maladaptive behavior (g = 0.519), and to a lesser extent, adaptive behavior/life skills (g = 0.239). No other study, intervention, or participant characteristic moderated outcomes. PIIs with children with ASD tend to be effective across a variety of circumstances.
Mesh-Begriff(e)	Child ; Humans ; Autism Spectrum Disorder/therapy ; Autistic Disorder ; Parents ; Child Development Disorders, Pervasive ; Communication
Sprache	Englisch
Erscheinungsdatum	2022-08-22
Erscheinungsland	United States
Dokumenttyp	Meta-Analysis ; Journal Article
ZDB-ID	391999-7
ISSN	1573-3432 ; 0162-3257
ISSN (online)	1573-3432
ISSN	0162-3257
DOI	10.1007/s10803-022-05688-8
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Outreach to Low-Income Homebound Older Adults to Increase Access to COVID-19 Self-Test Kits, Missouri, 2022.

Skinner, Karen E / Stoever, Anneliese / Zakibe, John R / Butler, Taylor / Kreuter, Matthew W

American journal of public health

2023 Band 114, Heft S1, Seite(n) S65–S68

Abstract: COVID-19 self-test kits were distributed to low-income, older adults (n = 2532) with their home-delivered or congregate meals in May 2022. Later, a convenience sample (n = 1108) were contacted for follow-up, and 606 (55%) were reached. Among 79% who ... ...

Abstract	COVID-19 self-test kits were distributed to low-income, older adults (n = 2532) with their home-delivered or congregate meals in May 2022. Later, a convenience sample (n = 1108) were contacted for follow-up, and 606 (55%) were reached. Among 79% who remembered getting the test, only 34% already had a test kit, but nearly all liked receiving it (91%) and reported they would use or had used it (93%). Partnering with meal-delivery service providers was feasible to increase access to COVID-19 self-tests for low-income older adults. (
Mesh-Begriff(e)	Humans ; Aged ; Missouri ; Self-Testing ; COVID-19/diagnosis ; Homebound Persons ; Poverty
Sprache	Englisch
Erscheinungsdatum	2023-11-09
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	121100-6
ISSN	1541-0048 ; 0090-0036 ; 0002-9572
ISSN (online)	1541-0048
ISSN	0090-0036 ; 0002-9572
DOI	10.2105/AJPH.2023.307485
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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