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  1. Article ; Online: Iran's burden of disease and burden of data collection.

    Hashemian, Seyed Mohammadreza / Miller, James

    Lancet (London, England)

    2022  Volume 400, Issue 10351, Page(s) 490

    MeSH term(s) Cost of Illness ; Data Collection ; Humans ; Iran/epidemiology
    Language English
    Publishing date 2022-07-31
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)01336-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Oxygenation Efforts for Iranian COVID-19 ARDS Patients: First 5-Day Crisis Experience Scenario.

    Hashemian, Seyed Mohammadreza / Khoundabi, Batoul / Tabarsi, Payam

    Tanaffos

    2021  Volume 19, Issue 3, Page(s) 173–175

    Language English
    Publishing date 2021-03-19
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mini-surgical Percutaneous Dilatational Tracheostomy (msPDT): Our Experience during the COVID-19 Pandemic.

    Rahmanzade, Ramin / Hashemian, Seyed MohammadReza

    The British journal of surgery

    2020  Volume 107, Issue 10, Page(s) e363

    MeSH term(s) COVID-19/epidemiology ; Contraindications, Procedure ; Dilatation/adverse effects ; Dilatation/methods ; Humans ; Minimally Invasive Surgical Procedures ; Pandemics ; SARS-CoV-2 ; Tracheostomy/adverse effects ; Tracheostomy/methods
    Keywords covid19
    Language English
    Publishing date 2020-08-05
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comment on: Safety and efficacy of Favipiravir in moderate to severe SARS-CoV-2 pneumonia.

    Hashemian, Seyed MohammadReza / Khoundabi, Batoul / Velayati, Ali Akbar

    International immunopharmacology

    2021  Volume 102, Page(s) 107693

    MeSH term(s) Amides/therapeutic use ; COVID-19 ; Humans ; Pyrazines ; SARS-CoV-2
    Chemical Substances Amides ; Pyrazines ; favipiravir (EW5GL2X7E0)
    Language English
    Publishing date 2021-05-28
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2021.107693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A review on modafinil: the characteristics, function, and use in critical care.

    Hashemian, Seyed MohammadReza / Farhadi, Tayebeh

    Journal of drug assessment

    2020  Volume 9, Issue 1, Page(s) 82–86

    Abstract: In critically ill patients, sleep is generally interrupted. Some factors that lead to such sleep interruption include the intensive care unit (ICU) circumstance, primary medical disease itself, mental stress, and impacts of many drugs and other ... ...

    Abstract In critically ill patients, sleep is generally interrupted. Some factors that lead to such sleep interruption include the intensive care unit (ICU) circumstance, primary medical disease itself, mental stress, and impacts of many drugs and other managements utilized to treat ICU patients. Another illness that may cause profound daytime somnolence is narcolepsy. Modafinil, methylphenidate and amphetamines are used as stimulants to treat symptoms, such as extreme daytime sleepiness, cataplexy and nocturnal sleep disruption. Such stimulants can increase awareness, improve perception and thinking, as well as assist in keeping people awake. The exact mechanism of action of modafinil is unclear.
    Language English
    Publishing date 2020-04-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2663094-1
    ISSN 2155-6660
    ISSN 2155-6660
    DOI 10.1080/21556660.2020.1745209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Virtual screening for potential inhibitors of β(1,3)-D-glucan synthase as drug candidates against fungal cell wall.

    Farhadi, Zinat / Farhadi, Tayebeh / Hashemian, Seyed MohammadReza

    Journal of drug assessment

    2020  Volume 9, Issue 1, Page(s) 52–59

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2020-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2663094-1
    ISSN 2155-6660
    ISSN 2155-6660
    DOI 10.1080/21556660.2020.1734010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nintedanib: a review of the properties, function, and usefulness to minimize COVID-19-induced lung injury.

    Hashemian, Seyed MohammadReza / Farhadi, Tayebeh / Varahram, Mohammad / Velayati, Ali Akbar

    Expert review of anti-infective therapy

    2022  Volume 21, Issue 1, Page(s) 7–14

    Abstract: Introduction: In severe COVID-19 patients, acute respiratory distress syndrome (ARDS)-induced lung injury regularly causes a pulmonary fibrotic phase. There is no approved therapy for the COVID-19-induced pulmonary fibrosis. However, administration of ... ...

    Abstract Introduction: In severe COVID-19 patients, acute respiratory distress syndrome (ARDS)-induced lung injury regularly causes a pulmonary fibrotic phase. There is no approved therapy for the COVID-19-induced pulmonary fibrosis. However, administration of an anti-fibrotic agent, in the early acute phase of the severe COVID-19 with ARDS, may improve the infection outcomes.
    Areas covered: In this review, the main characteristics of nintedanib and its usefulness to treat COVID-19-induced fibrosis were studied. In July 2022, a literature search was performed from PubMed, Google Scholar, and the WHO databases for studies focusing on the properties, function, efficacy, and safety of nintedanib against different lung injuries.
    Expert opinion: Nintedanib interferes with lung fibrosis and tumor angiogenesis by targeting multiple receptor tyrosine kinases (RTKs). Loss of RTKs activity leads to blocking downstream signaling cascades and inhibiting the proliferation and migration of lung fibroblasts. Targeting RTKs may be useful in the treatment of COVID-19 lung fibrosis. Nintedanib may be a superior agent compared to pirfenidone for the treatment of COVID-19 ARDS-related pulmonary fibrosis. Investigation of the efficacy and safety of nintedanib in the early stages of COVID-19-induced ARDS is critical since it may decrease the oxygen dependency and degree of lung fibrosis after the hospital discharge.
    MeSH term(s) Humans ; Lung Injury/drug therapy ; Lung Injury/etiology ; Idiopathic Pulmonary Fibrosis/pathology ; COVID-19/complications ; Respiratory Distress Syndrome/drug therapy ; Respiratory Distress Syndrome/etiology
    Chemical Substances nintedanib (G6HRD2P839)
    Language English
    Publishing date 2022-12-08
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2023.2153116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Prognostic Value of Platelet to Lymphocyte Ratio (PLR) and Neutrophil to Lymphocyte Ratio (NLR) in Patients with Pulmonary Hypertension.

    Shahmoradi, Zahra / Malekmohammad, Majid / Najafi, Ghazal / Heshmatnia, Jalal / Emami, Habib / Ardehali, Seyed Hossein / Shojaei, Seyedpouzhia / Hashemian, Seyed MohammadReza

    Tanaffos

    2023  Volume 21, Issue 4, Page(s) 480–486

    Abstract: Background: Pulmonary hypertension (PH) is a hemodynamic and pathophysiological disease defined by a mean pulmonary artery pressure of ≥20 mm Hg. Pulmonary hypertension severity and prognosis play an essential role in the management of these patients. ... ...

    Abstract Background: Pulmonary hypertension (PH) is a hemodynamic and pathophysiological disease defined by a mean pulmonary artery pressure of ≥20 mm Hg. Pulmonary hypertension severity and prognosis play an essential role in the management of these patients. The aim of this study was to evaluate the prognostic value of platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) in patients with PH referred to Masih Daneshvari Hospital, Tehran, Iran.
    Materials and methods: A total of 61 patients with PH referred to Masih Daneshvari Hospital in Tehran were enrolled. Patients' information such as age, sex, type of PH, echocardiographic data, and blood cell count, including platelet, lymphocyte, and neutrophil count, hemoglobin, and RDW, were collected in each follow-up.
    Results: Out of 61 patients with PH, 27 (44.3%) were male, and 34 (55.7%) were female. The mean age of the patients was 43.19 ± 2.25 years. Our results showed that during hospitalization, PLR decreased from 13.2 to 9.7, and NLR also decreased from 4.49 to 3.08. Neither PLR nor NLR was associated with gender. However, both PLR and NLR showed a significant difference between deceased vs. discharged patients and were significantly lower in the patients who died.
    Conclusion: Both PLR and NLR decreased during hospitalization in patients with PH, and this decrease was greater in the patients who died, suggesting these indicators as potential prognostic markers for the disease.
    Language English
    Publishing date 2023-08-03
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Efficacy of Early Prone Positioning Combined with Noninvasive Ventilation in COVID-19.

    Hashemian, Seyed Mohammadreza / Jamaati, Hamidreza / Malekmohammad, Majid / Tabarsi, Payam / Khoundabi, Batoul / Shafigh, Navid

    Tanaffos

    2021  Volume 20, Issue 2, Page(s) 82–85

    Language English
    Publishing date 2021-12-04
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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