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  1. Article ; Online: Ancient Chinese Formula Qiong-Yu-Gao Protects Against Cisplatin-Induced Nephrotoxicity Without Reducing Anti-tumor Activity.

    Teng, Zhi-Ying / Cheng, Xiao-Lan / Cai, Xue-Ting / Yang, Yang / Sun, Xiao-Yan / Xu, Jin-Di / Lu, Wu-Guang / Chen, Jiao / Hu, Chun-Ping / Zhou, Qian / Wang, Xiao-Ning / Li, Song-Lin / Cao, Peng

    Scientific reports

    2015  Volume 5, Page(s) 15592

    Abstract: ... we investigated whether Qiong-Yu-Gao (QYG), a popular traditional Chinese medicinal formula described 840 years ...

    Abstract Cisplatin is a highly effective anti-cancer chemotherapeutic agent; however, its clinical use is severely limited by serious side effects, of which nephrotoxicity is the most important. In this study, we investigated whether Qiong-Yu-Gao (QYG), a popular traditional Chinese medicinal formula described 840 years ago, exhibits protective effects against cisplatin-induced renal toxicity. Using a mouse model of cisplatin-induced renal dysfunction, we observed that pretreatment with QYG attenuated cisplatin-induced elevations in blood urea nitrogen and creatinine levels, ameliorated renal tubular lesions, reduced apoptosis, and accelerated tubular cell regeneration. Cisplatin-mediated elevations in tumor necrosis factor alpha (TNF-α) mRNA, interleukin-1 beta (IL-1β) mRNA, and cyclooxygenase-2 (COX-2) protein in the kidney were also significantly suppressed by QYG treatment. Furthermore, QYG reduced platinum accumulation in the kidney by decreasing the expression of copper transporter 1 and organic cation transporter 2. An in vivo study using implanted Lewis lung cancer cells revealed that concurrent administration of QYG and cisplatin did not alter the anti-tumor activity of cisplatin. Our findings suggest that the traditional Chinese medicinal formula QYG inhibits cisplatin toxicity by several mechanisms that act simultaneously, without compromising its therapeutic efficacy. Therefore, QYG may be useful in the clinic as a protective agent to prevent cisplatin-induced nephrotoxicity.
    MeSH term(s) Animals ; Carcinoma, Lewis Lung/drug therapy ; Carcinoma, Lewis Lung/metabolism ; Carcinoma, Lewis Lung/pathology ; Cell Line, Tumor ; Cisplatin/adverse effects ; Cisplatin/pharmacology ; Cyclooxygenase 2/biosynthesis ; Drugs, Chinese Herbal/pharmacology ; Gene Expression Regulation/drug effects ; Interleukin-1beta/biosynthesis ; Kidney Diseases/chemically induced ; Kidney Diseases/metabolism ; Kidney Diseases/pathology ; Kidney Diseases/prevention & control ; Mice ; Tumor Necrosis Factor-alpha/biosynthesis
    Chemical Substances Drugs, Chinese Herbal ; IL1B protein, mouse ; Interleukin-1beta ; Tumor Necrosis Factor-alpha ; Ptgs2 protein, mouse (EC 1.14.99.-) ; Cyclooxygenase 2 (EC 1.14.99.1) ; Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2015-10-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep15592
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  2. Article ; Online: The Development History, Problems and Suggestions for Marine Scientific and Technological Innovation in Guangdong Province

    Qiong WANG

    Haiyang Kaifa yu guanli, Vol 40, Iss 11, Pp 37-

    2023  Volume 45

    Abstract: Marine science and technology is an important engine and driving force to support the construction of a strong marine country and a strong marine province. This paper focuses on the evolution of marine scientific and technological strategy, marine survey, ...

    Abstract Marine science and technology is an important engine and driving force to support the construction of a strong marine country and a strong marine province. This paper focuses on the evolution of marine scientific and technological strategy, marine survey, to sort out the development history which has milestone significance and played a major role in promoting Guangdong's marine scientific and technological innovation and development since the founding of the People's Republic of China. This paper points out the existing problems in the innovation and development of marine science and technology in Guangdong Province from the perspectives of the management system and mechanism of marine science and technology innovation investment, the introduction of high-level talents in the marine field and the construction of innovation platform. On this basis, considering the needs of building a strong marine province in Guangdong, the corresponding countermeasures and suggestions for the construction of the system and mechanism for the innovation and development of marine science and technology are put forward, creating a highland for marine science and technology talents and innovation platforms, and increasing the channels and efforts of marine scientific and technological innovation.
    Keywords marine science and technology innovation ; development history ; suggestions ; guangdong province ; Oceanography ; GC1-1581
    Subject code 900
    Language Chinese
    Publishing date 2023-11-01T00:00:00Z
    Publisher Editorial Office of Ocean Development and Management
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Bacteremia caused by

    Zhang, Ranran / Wang, Nuan / Li, Qiong / Cao, Jingrun / Shi, Ning / Niu, Qiong / Liu, Chengxia

    Quantitative imaging in medicine and surgery

    2024  Volume 14, Issue 4, Page(s) 3162–3168

    Language English
    Publishing date 2024-03-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-23-1390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Maintenance of adipose progenitors in adipogenesis.

    Wang, Guan / Wang, Qiong A

    Nature metabolism

    2023  Volume 5, Issue 6, Page(s) 917–919

    MeSH term(s) Humans ; Adipogenesis ; Obesity ; Adipocytes ; Adiposity
    Language English
    Publishing date 2023-06-19
    Publishing country Germany
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2522-5812
    ISSN (online) 2522-5812
    DOI 10.1038/s42255-023-00810-1
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  5. Article ; Online: Updated RDP taxonomy and RDP Classifier for more accurate taxonomic classification.

    Wang, Qiong / Cole, James R

    Microbiology resource announcements

    2024  Volume 13, Issue 4, Page(s) e0106323

    Abstract: The RDP Classifier is one of the most popular machine learning approaches for taxonomic classification due to its robustness and relatively high accuracy. Both the RDP taxonomy and RDP Classifier have been updated to incorporate newly described taxa and ... ...

    Abstract The RDP Classifier is one of the most popular machine learning approaches for taxonomic classification due to its robustness and relatively high accuracy. Both the RDP taxonomy and RDP Classifier have been updated to incorporate newly described taxa and recent changes to prokaryotic nomenclature.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.01063-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Characteristics, hotspots, and prospects of short video research: A review of papers published in China from 2012 to 2022.

    Yuan, Yaozong / Wang, Qiong

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e24885

    Abstract: In recent years, due to the increase in their global popularity, short video applications have become an important topic of research. The number of users has now exceeded one billion in China; accordingly, Chinese researchers have conducted many studies ... ...

    Abstract In recent years, due to the increase in their global popularity, short video applications have become an important topic of research. The number of users has now exceeded one billion in China; accordingly, Chinese researchers have conducted many studies on short videos. Their findings can serve as important references for both theoretical research on and the practical development of short videos worldwide. In this study, we used bibliometrics method and the CiteSpace application to analyze the content of 2163 representative research papers on short videos published in China from 2012 to 2022. The number of such papers is increasing annually in China; moreover, several core groups of authors and research institutions focusing on short video research have already been formed. Some popular topics of research on these videos include the main characteristics of short videos, phenomenon of media convergence based on short videos, and application scenarios of short videos. Over the years, research on the popular short video application Douyin has been increasing, as well. The research results indicate that issues such as the marketing of short knowledge videos, standardized management of short video platforms, and impact of these videos on the education of college students are expected to become popular subjects of scholarly research in the near future.
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24885
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  7. Article: Data independent acquisition reveals in-depth serum proteome changes in uremic pruritus.

    Wen-Jing, Zhao / Rui-Zhi, Tan / Si-Yuan, He / Xiao-Mei, Du / Qiong-Dan, Hu / Xiao-Qian, Zhang / Wen-Hua, Huang / Hong-Wei, Su / Jian, Liu / Qiong, Zhang / Li, Wang

    Frontiers in physiology

    2024  Volume 15, Page(s) 1287072

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2024.1287072
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  8. Article ; Online: Becoming less beige with age

    Anying Song / Qiong A Wang

    eLife, Vol

    2023  Volume 12

    Abstract: The production of beige adipocytes following cold exposure is blocked as mice get older and leads to changes in the expression of metabolic genes. ...

    Abstract The production of beige adipocytes following cold exposure is blocked as mice get older and leads to changes in the expression of metabolic genes.
    Keywords adipocytes ; metabolism ; ageing ; cold exposure ; Medicine ; R ; Science ; Q ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher eLife Sciences Publications Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: How digital finance impacts listed companies' green innovation in China: a product market perspective.

    Wang, Qiong / Wang, Shangyi / Wang, Chengyuan / Hu, Dan

    Environmental science and pollution research international

    2024  Volume 31, Issue 13, Page(s) 19856–19870

    Abstract: We empirically test whether and how digital finance impact green innovation utilizing data from Chinese listed companies and the Digital Inclusive Finance Index at the city level over the period from 2011 to 2020. The results show the following: (a) ... ...

    Abstract We empirically test whether and how digital finance impact green innovation utilizing data from Chinese listed companies and the Digital Inclusive Finance Index at the city level over the period from 2011 to 2020. The results show the following: (a) digital finance has a positive impact on green innovation, (b) improving consumer demand and strengthening market competition are two important influence channels, (c) customer concentration and corporate social responsibility are two important moderating variables that affect the aforementioned product market mechanisms, and (d) the positive impact of digital finance is more prominent within state-owned enterprises, companies with high financial risks, economically underdeveloped regions, and low-polluting industries. This research provides insights for China and similar economies on how to leverage the significant role of digital finance in achieving their net-zero-carbon targets.
    MeSH term(s) Humans ; China ; Asian People ; Carbon ; Industry ; Economic Development
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2024-02-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32442-7
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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  10. Article ; Online: A migrating fishbone.

    Shi, Lei / Wei, SaiLing / Yan, Qiong / Xie, Jia Xun / Wu, JinYu / Wang, Lisheng

    Endoscopy

    2024  Volume 56, Issue S 01, Page(s) E116–E117

    Language English
    Publishing date 2024-02-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2233-2968
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 162: Show issues

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