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  1. Book ; Online ; E-Book: Nanocarrier Vaccines

    Chavda, Vivek P. / Apostolopoulos, Vasso

    Biopharmaceutics-Based Fast Track Development

    2024  

    Language English
    Size 1 online resource (519 pages)
    Edition 1st ed.
    Publisher John Wiley & Sons, Incorporated
    Publishing place Newark
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9781394175468 ; 9781394174683 ; 1394175469 ; 1394174683
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Advanced Vaccination Technologies for Infectious and Chronic Diseases

    Apostolopoulos, Vasso / Vora, Lalitkumar K. / Chavda, Vivek P.

    A Guide to Vaccinology

    (Developments in Immunology Series)

    2024  

    Series title Developments in Immunology Series
    Subject code 615.372
    Language English
    Size 1 online resource (530 pages)
    Edition 1st ed.
    Publisher Elsevier Science & Technology
    Publishing place San Diego
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-443-18565-4 ; 0-443-18564-6 ; 978-0-443-18565-6 ; 978-0-443-18564-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Mosaic receptor binding domain nanoparticles: towards fourth-generation vaccination.

    Chavda, Vivek P / Apostolopoulos, Vasso

    Nanomedicine (London, England)

    2023  Volume 18, Issue 19, Page(s) 1223–1226

    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Editorial
    ZDB-ID 2277839-1
    ISSN 1748-6963 ; 1743-5889
    ISSN (online) 1748-6963
    ISSN 1743-5889
    DOI 10.2217/nnm-2022-0316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A new era of immune therapeutics for pancreatic cancer: Monoclonal antibodies paving the way.

    Balar, Pankti C / Apostolopoulos, Vasso / Chavda, Vivek P

    European journal of pharmacology

    2024  Volume 969, Page(s) 176451

    Abstract: Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, remains a devastating disease with a dismal prognosis and limited survival rates. Despite various drug treatments and regimens showing promise in managing the disease, the clinical ... ...

    Abstract Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, remains a devastating disease with a dismal prognosis and limited survival rates. Despite various drug treatments and regimens showing promise in managing the disease, the clinical outcomes have not significantly improved. Immunotherapy however, has become a forefront area in pancreatic cancer treatment. This approach comprises a range of agents, including small molecule drugs, antibodies, combination therapies, and vaccines. In the last 5-8 years, there has been an upsurge of research into the use of monoclonal antibodies to block receptors on cancer or immune cells, revolutionising cancer treatment and management. Several targets have been identified and studied, with the most encouraging noted in relation to checkpoint markers, namely, antibodies targeting anti-programmed cell death 1 (PD-1) and its receptor PD-L1. Herein, we present the clinical developments in immunotherapy in the last 5 years especially those which have been tested in humans against pancreatic cancer.
    MeSH term(s) Humans ; Antibodies, Monoclonal/therapeutic use ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/metabolism ; Carcinoma, Pancreatic Ductal/drug therapy ; Combined Modality Therapy ; Immunotherapy
    Chemical Substances Antibodies, Monoclonal
    Language English
    Publishing date 2024-02-24
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 80121-5
    ISSN 1879-0712 ; 0014-2999
    ISSN (online) 1879-0712
    ISSN 0014-2999
    DOI 10.1016/j.ejphar.2024.176451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rare monkeypox: Is it really a threat to the elderly?

    Chavda, Vivek P / Apostolopoulos, Vasso

    Maturitas

    2022  Volume 163, Page(s) 90–91

    MeSH term(s) Aged ; Humans ; Mpox (monkeypox)
    Language English
    Publishing date 2022-06-09
    Publishing country Ireland
    Document type Editorial
    ZDB-ID 80460-5
    ISSN 1873-4111 ; 0378-5122
    ISSN (online) 1873-4111
    ISSN 0378-5122
    DOI 10.1016/j.maturitas.2022.05.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: How do we change our approach to COVID with the changing face of disease?

    Apostolopoulos, Vasso / Feehan, Jack / Chavda, Vivek P

    Expert review of anti-infective therapy

    2024  , Page(s) 1–9

    Abstract: Introduction: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, ... ...

    Abstract Introduction: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, lockdowns and social distancing, disrupted economies and strained healthcare. Viral mutations highlighted the need for flexible strategies and strong public health infrastructure, with global collaboration crucial for pandemic control.
    Areas covered: (i) Revisiting diagnostic strategies, (ii) adapting to the evolving challenge of the virus, (iii) vaccines against new variants, (iv) vaccine hesitancy in the light of the evolving disease, (v) treatment strategies, (vi) hospital preparedness for changing clinical needs, (vii) global cooperation and data sharing, (viii) economic implications, and (ix) education and awareness- keeping communities informed.
    Expert opinion: The COVID-19 crisis forced unprecedented adaptation, emphasizing public health readiness, global unity, and scientific advancement. Key lessons highlight the importance of adaptability and resilience against uncertainties. As the pandemic evolves into a 'new normal,' ongoing vigilance, improved understanding, and available vaccines and treatments equip us for future challenges. Priorities now include proactive pandemic strategies, early warnings, supported healthcare, public education, and addressing societal disparities for better health resilience and sustainability.
    Language English
    Publishing date 2024-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2024.2345881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Global impact of delta plus variant and vaccination.

    Chavda, Vivek P / Apostolopoulos, Vasso

    Expert review of vaccines

    2022  Volume 21, Issue 5, Page(s) 597–600

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Vaccination
    Language English
    Publishing date 2022-02-28
    Publishing country England
    Document type Editorial
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2022.2044800
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Omicron variant (B.1.1.529) of SARS-CoV-2: Threat for the elderly?

    Chavda, Vivek P / Apostolopoulos, Vasso

    Maturitas

    2022  Volume 158, Page(s) 78–81

    MeSH term(s) Aged ; COVID-19 ; Humans ; Mutation ; SARS-CoV-2
    Language English
    Publishing date 2022-01-29
    Publishing country Ireland
    Document type Editorial
    ZDB-ID 80460-5
    ISSN 1873-4111 ; 0378-5122
    ISSN (online) 1873-4111
    ISSN 0378-5122
    DOI 10.1016/j.maturitas.2022.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: SARS-CoV-2: Immunopeptidomics and Other Immunological Studies.

    Chavda, Vivek P / Redwan, Elrashdy M

    Vaccines

    2022  Volume 10, Issue 11

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has produced a significant continuing epidemic worldwide [ ... ]. ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has produced a significant continuing epidemic worldwide [...].
    Language English
    Publishing date 2022-11-21
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10111975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 vaccine design and vaccination strategy for emerging variants.

    Chavda, Vivek P / Apostolopoulos, Vasso

    Expert review of vaccines

    2022  Volume 21, Issue 10, Page(s) 1359–1361

    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines ; Humans ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-08-16
    Publishing country England
    Document type Editorial
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2022.2112571
    Database MEDical Literature Analysis and Retrieval System OnLINE

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