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  1. Article: [Existence forms of Tiantian Capsules and its raw material Aloe in rats].

    Zhang, Jing / Hao, Bei-Quan / Li, Yin-Qing / Wang, Guang-Lu / Xu, Feng / Liu, Guang-Xue / Shang, Ming-Ying / Cai, Shao-Qing

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2024  Volume 49, Issue 6, Page(s) 1641–1660

    Abstract: This study explored the existence forms(original constituents and metabolites) of Tiantian Capsules ... Aloe, and Tiantian Capsules without Aloe in rats for the first time, aiming to clarify the contribution ... of Aloe to the existence form of Tiantian Capsules. Rats were administrated with corresponding drugs ...

    Abstract This study explored the existence forms(original constituents and metabolites) of Tiantian Capsules, Aloe, and Tiantian Capsules without Aloe in rats for the first time, aiming to clarify the contribution of Aloe to the existence form of Tiantian Capsules. Rats were administrated with corresponding drugs by gavage once a day for seven consecutive days. All urine and feces samples were collected during the seven days of administration, and blood samples were collected 0.5, 1, and 1.5 h after the last administration. UHPLC-Q-TOF-MS was employed to detect and identify the original constituents and metabolites in the samples. A total of 34, 28, and 2 original constituents and 64, 94, and 0 metabolites were identified in the samples of rats administrated with Aloe, Tiantian Capsules, and Tiantian Capsules without Aloe, respectively. The main metabolic reactions were methylation, hydrogenation, hydroxylation, dehydroxylation, glucuronidation, and sulfation. This study clarified for the first time the existence forms and partial metabolic pathways of Aloe, Tiantian Capsules, and Tiantian Capsules without Aloe in rats, laying a foundation for revealing their effective forms. The findings are of great significance to the research on the functioning mechanism and quality control of Aloe and Tiantian Capsules.
    MeSH term(s) Rats ; Animals ; Chromatography, High Pressure Liquid ; Aloe ; Drugs, Chinese Herbal/metabolism ; Administration, Oral ; Feces ; Capsules
    Chemical Substances Drugs, Chinese Herbal ; Capsules
    Language Chinese
    Publishing date 2024-03-11
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20231215.201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ‘Enclosure with Chinese characteristics’: a Polanyian approach to the origins and limits of land commodification in China

    Liu, Tiantian

    The Journal of Peasant Studies. 2023 June 07, v. 50, no. 4 p.1347-1375

    2023  

    Abstract: Based on archival research and interviews with state officials and state-affiliated academics, this article argues that the Chinese state's decision to slow down rural land transfer since 2017 is a Polanyian countermovement against the adverse ... ...

    Abstract Based on archival research and interviews with state officials and state-affiliated academics, this article argues that the Chinese state's decision to slow down rural land transfer since 2017 is a Polanyian countermovement against the adverse consequences of earlier, excessive labor and land commodification. The central government's drive for land consolidation is contingent upon and structurally constrained by the process of rural labor commodification. By focusing on connections between land and labor and situating agrarian transformation under the context of national capital accumulation, this study examines land beyond agriculture and argues for the continued importance of the classical Agrarian Questions.
    Keywords capital ; labor ; peasantry ; rural areas ; China ; Land transfer/concentration ; land commodification ; labor commodification ; Polanyian double movement ; embeddedness ; national capital accumulation ; the Chinese state ; global crisis
    Language English
    Dates of publication 2023-0607
    Size p. 1347-1375.
    Publishing place Routledge
    Document type Article ; Online
    ISSN 1743-9361
    DOI 10.1080/03066150.2021.1979967
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Editorial: Nutritional interventions on age-related neurodegenerative diseases.

    Zhang, Tiantian / Liu, Zhigang / Mi, Yashi

    Frontiers in aging neuroscience

    2023  Volume 15, Page(s) 1215586

    Language English
    Publishing date 2023-06-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2023.1215586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Electrohydrogenation of Nitriles with Amines by Cobalt Catalysis.

    Wang, Tiantian / He, Fangfang / Jiang, Wei / Liu, Jie

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 7, Page(s) e202316140

    Abstract: Catalytic hydrogenation of nitriles represents an efficient and sustainable one-step synthesis of valuable bulk and fine chemicals. We report herein a molecular cobalt electrocatalyst for selective hydrogenative coupling of nitriles with amines using ... ...

    Abstract Catalytic hydrogenation of nitriles represents an efficient and sustainable one-step synthesis of valuable bulk and fine chemicals. We report herein a molecular cobalt electrocatalyst for selective hydrogenative coupling of nitriles with amines using protons as the hydrogen source. The key to success for this reductive reaction is the use of an electrocatalytic approach for efficient cobalt-hydride generation through a sequence of cathodic reduction and protonation. As only electrons (e
    Language English
    Publishing date 2024-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202316140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: scCGImpute

    Tiantian Liu / Yuanyuan Li

    Applied Sciences, Vol 13, Iss 7936, p

    An Imputation Method for Single-Cell RNA Sequencing Data Based on Similarities between Cells and Relationships among Genes

    2023  Volume 7936

    Abstract: Single-cell RNA sequencing (scRNA-seq) has become a powerful technique to investigate cellular heterogeneity and complexity in various fields by revealing the gene expression status of individual cells. Despite the undeniable benefits of scRNA-seq, it is ...

    Abstract Single-cell RNA sequencing (scRNA-seq) has become a powerful technique to investigate cellular heterogeneity and complexity in various fields by revealing the gene expression status of individual cells. Despite the undeniable benefits of scRNA-seq, it is not immune to its inherent limitations, such as sparsity and noise, which would hinder downstream analysis. In this paper, we introduce scCGImpute, a model-based approach for addressing the challenges of sparsity in scRNA-seq data through imputation. After identifying possible dropouts using mixed models, scCGImpute takes advantage of the cellular similarity in the same subpopulation to impute and then uses random forest regression to obtain the final imputation. scCGImpute only imputes the likely dropouts without changing the non-dropout data and can use information from the similarity of cells and genetic correlation simultaneously. Experiments on simulation data and real data were made, respectively, to evaluate the performance of scCGImpute in terms of gene expression recovery and clustering analysis. The results demonstrated that scCGImpute can effectively restore gene expression and improve the identification of cell types.
    Keywords scRNA-seq ; sparsity ; imputation ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 612
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Enantiomerization and enantioselective bioaccumulation of diclofop-methyl in tubifex worms.

    Liu, Tiantian / Duan, Xinhong

    Chirality

    2023  Volume 36, Issue 1, Page(s) e23618

    Abstract: In this study, the hydrolysis of diclofop-methyl (DM) in aqueous system and the bioaccumulation of its main metabolite, Diclofop (DA), in the tubifex worms were investigated using enantioselective high-performance liquid chromatography. With the addition ...

    Abstract In this study, the hydrolysis of diclofop-methyl (DM) in aqueous system and the bioaccumulation of its main metabolite, Diclofop (DA), in the tubifex worms were investigated using enantioselective high-performance liquid chromatography. With the addition of tubifex, rapid hydrolysis was observed for DM. It is revealed that the hydrolysis of DM in the water and the accumulation of DA in the worms were both enantioselective. Meanwhile, either the hydrolysis amount or the levels of enantioselectivity were influenced by the tubifex. After incubated for 24 h, about 94.6% of the DM was hydrolyzed and the enantiomer fraction of metabolite (DA) deviated from 0.5 with R-DA significantly higher than S-DA. The enantiopure S-DM and R-DM and S-DA and R-DA were incubated, and enantiomerizations were detected between the two DM enantiomers with S-form inversing into R-form and vice versa. It was found that the S-DM exhibited a higher tendency to invert than the R-DM.
    MeSH term(s) Animals ; Stereoisomerism ; Bioaccumulation ; Halogenated Diphenyl Ethers/chemistry ; Oligochaeta/chemistry ; Oligochaeta/metabolism ; Water/chemistry
    Chemical Substances dichlorfop-methyl (9T8QCB25UO) ; Halogenated Diphenyl Ethers ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1011639-4
    ISSN 1520-636X ; 0899-0042
    ISSN (online) 1520-636X
    ISSN 0899-0042
    DOI 10.1002/chir.23618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Adaptive Event-Triggered Output-Feedback Control Against Unknown Control Directions and Unknown Intrinsic Growth.

    Guo, Tiantian / Liu, Yungang

    IEEE transactions on cybernetics

    2023  Volume 53, Issue 12, Page(s) 7609–7621

    Abstract: This article addresses global stabilization via disparate event-triggered output feedback for a class of uncertain nonlinear systems. Typically, the systems allow unknown control directions and unmeasurable-state dependent growth simultaneously. Actually, ...

    Abstract This article addresses global stabilization via disparate event-triggered output feedback for a class of uncertain nonlinear systems. Typically, the systems allow unknown control directions and unmeasurable-state dependent growth simultaneously. Actually, in the context of the latter ingredient, there has been no any continuous control strategy that has allowed the former ingredient so far. Hence, one cannot solve the event-triggered control problem based on corresponding continuous feedback as done in the emulation-based method. In view of the unsolvability, we pursue a nonemulation-based strategy, directly conducting event-triggered control design. First, a parameterized output feedback controller incorporating a dynamic high gain is designed, which would globally stabilize the system once the adjustable parameter therein is suitable. Then, an event-triggering mechanism is developed to not only decide when the controller is sampled/executed but also determine which constant value the adjustable parameter takes. Just due to the instantly varying (discontinuous) adjustable parameter, the feedback ability of the controller is large enough, making it possible to solve the control design problem in the event-triggered framework. A simulation example is provided to verify the effectiveness and advantage of the proposed approach.
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article
    ISSN 2168-2275
    ISSN (online) 2168-2275
    DOI 10.1109/TCYB.2022.3182137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Aquatic plant allelochemicals inhibit the growth of microalgae and cyanobacteria in aquatic environments.

    Wang, Tiantian / Liu, Haicheng

    Environmental science and pollution research international

    2023  Volume 30, Issue 48, Page(s) 105084–105098

    Abstract: Excess nitrogen and phosphorus nutrients in the aquatic environment result in the growth of algal cells and water eutrophication, which adversely affect the aquatic environment and human health. Therefore, discovering a safe and efficient algae ... ...

    Abstract Excess nitrogen and phosphorus nutrients in the aquatic environment result in the growth of algal cells and water eutrophication, which adversely affect the aquatic environment and human health. Therefore, discovering a safe and efficient algae suppression method is necessary to ensure the ecological safety of water. Recently, the allelopathic effects of aquatic plants on algae have attracted extensive attention from researchers. This review demonstrates the current research hotspot of allelopathic algal inhibition in aquatic plants and lists the common aquatic plant species and allelochemicals. In addition, the inhibition mechanism of allelochemicals from aquatic plants on algae is systematically discussed. Moreover, the key factors affecting the inhibition of allelopathy in algae, such as pH, temperature, algal cell density, and concentration of allelochemicals, are summarized. The present utilization modes of allelochemicals on algae are also presented. Finally, the problems existing in the study of allelopathic algal inhibition of aquatic plants are highlighted, and suggestions for further research are proposed.
    MeSH term(s) Humans ; Microalgae ; Pheromones/pharmacology ; Plants ; Allelopathy ; Cyanobacteria ; Water
    Chemical Substances Pheromones ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-09-23
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-29994-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: IremulbNet: Rethinking the inverted residual architecture for image recognition.

    Su, Tiantian / Liu, Anan / Shi, Yongran / Zhang, Xiaofeng

    Neural networks : the official journal of the International Neural Network Society

    2024  Volume 172, Page(s) 106140

    Abstract: An increasing need of running Convolutional Neural Network (CNN) models on mobile devices encourages the studies on efficient and lightweight neural network model. In this paper, an Inverse Residual Multi-Branch Network named IremulbNet is proposed to ... ...

    Abstract An increasing need of running Convolutional Neural Network (CNN) models on mobile devices encourages the studies on efficient and lightweight neural network model. In this paper, an Inverse Residual Multi-Branch Network named IremulbNet is proposed to solve the problem of insufficient classification accuracy in existing lightweight network models. The core module of this model is to reconstruct an inverse residual structure, in which a special feature fusion method, multi-branch feature extraction, and depthwise separable convolution techniques are used to improve the classification accuracy. The performance of model is tested using image databases. Experimental results show that for the fine-grained image dataset Imagenet-woof, IremulbNet achieved 10.9%, 12.2%, and 15.3% higher accuracy than that of MobileNet V3, ShuffleNet V2, and PeleeNet, respectively. Moreover, it can reduce inference time (GPU) about 42.09% and 75.56% compared to classic ResNet50 and DenseNet121.
    MeSH term(s) Databases, Factual ; Neural Networks, Computer ; Recognition, Psychology
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 740542-x
    ISSN 1879-2782 ; 0893-6080
    ISSN (online) 1879-2782
    ISSN 0893-6080
    DOI 10.1016/j.neunet.2024.106140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Research advances in exosomes involved in the occurrence, development and clinical diagnosis and treatment of sepsis].

    Zhao, Yilin / Liu, Tiantian / Wang, Chunxia

    Zhonghua wei zhong bing ji jiu yi xue

    2024  Volume 36, Issue 2, Page(s) 221–224

    Abstract: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host immune response to infection. The development of sepsis is accompanied by the secretion of exosomes by a variety of cells, including non-coding RNA, metabolic small molecules ... ...

    Abstract Sepsis is a life-threatening organ dysfunction caused by a dysregulated host immune response to infection. The development of sepsis is accompanied by the secretion of exosomes by a variety of cells, including non-coding RNA, metabolic small molecules and proteins, which play an important role in immune inflammatory response, oxidative stress, and coagulation dysfunction. The rapid development of new detection technologies has promoted the application of exosomes in the early warning, severity stratification, treatment effect and prognosis evaluation of sepsis. This article reviews the new detection technology of exosomes, the involvement of exosomes in the pathological progress of sepsis, and the latest progress in the early diagnosis, disease assessment and treatment of sepsis, in order to provide new ideas for the diagnosis and treatment of sepsis.
    MeSH term(s) Humans ; Exosomes ; Sepsis/diagnosis ; Sepsis/therapy ; Blood Coagulation ; Oxidative Stress
    Language Chinese
    Publishing date 2024-03-05
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ISSN 2095-4352
    ISSN 2095-4352
    DOI 10.3760/cma.j.cn121430-20230809-00601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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