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Book: Essentials of OCT in ocular disease

Agarwal, Amar / Kumar, Dhivya Ashok

2015

Author's details	Amar Agarwal ; Dhivya Ashok Kumar
Keywords	Eye Diseases / diagnosis ; Eye Diseases / surgery ; Tomography, Optical Coherence / methods
Language	English
Size	XVIII, 245 S. : zahlr. Ill., graph. Darst.
Publisher	Thieme
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
Note	Includes bibliographical references and index
HBZ-ID	HT018731555
ISBN	978-1-62623-098-9 ; 9781626230996 ; 1-62623-098-6 ; 1626230994
Database	Catalogue ZB MED Medicine, Health

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2015 A 2949	available for loan (reading room)	Lesesaal EG

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Article ; Online: A kinesin mimics DNA.

Kumar, Dhivya / Reiter, Jeremy F

Nature cell biology

2022 Volume 24, Issue 7, Page(s) 1015–1016

MeSH term(s)	DNA/genetics ; Kinesins/genetics ; Microtubules
Chemical Substances	DNA (9007-49-2) ; Kinesins (EC 3.6.4.4)
Language	English
Publishing date	2022-07-07
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	1474722-4
ISSN	1476-4679 ; 1465-7392
ISSN (online)	1476-4679
ISSN	1465-7392
DOI	10.1038/s41556-022-00958-0
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Article ; Online: Pre-Descemet's endothelial keratoplasty with glued intraocular lens implantation with pinhole pupilloplasty in a case of ocular comorbidity in achromatopsia.

Kumar, Dhivya Ashok / Agarwal, Amar / Ravichandran, Swetha

Taiwan journal of ophthalmology

2024 Volume 14, Issue 1, Page(s) 112–116

Abstract: Ocular comorbidities can happen as congenital defective gene associations. We present a 37-year-old female patient who was mentally challenged and had coexisting achromatopsia gene abnormality on genetic analysis. She was operated in childhood for ... ...

Abstract	Ocular comorbidities can happen as congenital defective gene associations. We present a 37-year-old female patient who was mentally challenged and had coexisting achromatopsia gene abnormality on genetic analysis. She was operated in childhood for congenital cataract, and posterior chamber intraocular lens (IOL) was implanted at 10 years of age elsewhere. The patient presented 27 years later with luxated IOL with endothelial decompensation. There was a coexisting steep and thin cornea noted on corneal topography. She was managed with pre-Descemet's endothelial keratoplasty with transpositioning of posterior chamber IOL to glued IOL with single-pass four-throw pupilloplasty. Postoperatively, the cornea was clear with centered glued IOL. The lesser postanesthetic challenges and faster rehabilitation are obtained in combination procedures with reduced complications in such rare scenarios.
Language	English
Publishing date	2024-03-15
Publishing country	India
Document type	Case Reports
ZDB-ID	2652841-1
ISSN	2211-5072 ; 2211-5072
ISSN (online)	2211-5072
ISSN	2211-5072
DOI	10.4103/tjo.TJO-D-23-00172
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Article ; Online: Diagnostic Accuracy of Endotoxin and Endotoxin Binding Protein in Late-Onset Neonatal Sepsis.

Katta, Divya / Sridharan, Kopula Satyamoorthy / Balakrishnan, UmaMaheswari / Amboiram, Prakash / Dhivya, Gopi / Palraj, Kennedy Kumar

Indian journal of pediatrics

2024

Abstract: Objectives: To evaluate the diagnostic utility of endotoxin and endotoxin binding protein (EBP) for the diagnosis of late-onset neonatal sepsis (LOS) and compare it with the diagnostic utility of C-reactive protein (CRP).: Methods: This diagnostic ... ...

Abstract	Objectives: To evaluate the diagnostic utility of endotoxin and endotoxin binding protein (EBP) for the diagnosis of late-onset neonatal sepsis (LOS) and compare it with the diagnostic utility of C-reactive protein (CRP). Methods: This diagnostic study of neonates, both term and preterm, with clinical suspicion of LOS was conducted in a tertiary care institute in India between January 2021 and March 2023. Blood samples were collected for evaluating endotoxin and EBP along with culture. Endotoxin and EBP were measured with enzyme linked immunosorbent assay, CRP was measured by nephelometry method, and the results were compared with blood culture done with BACTEC (gold standard). Results: Out of 160 samples, 73 showed culture positivity. Endotoxin was positive in 81 samples and showed sensitivity of 84%, specificity of 78% and diagnostic accuracy of 81% (AUC 0.837, P value <0.001). EBP was positive in 82 samples and showed sensitivity of 80.8%, specificity of 73% and diagnostic accuracy of 76% (AUC 0.824, P value <0.001). CRP was positive in 105 samples and had sensitivity of 86%, specificity of 51% and diagnostic accuracy of 67% (AUC 0.827, P value <0.001). Conclusions: The present study showed endotoxin and EBP have higher specificity for diagnosing neonatal sepsis. As culture takes minimum 48 h, endotoxin and EBP can be utilized as biomarkers for diagnosis of sepsis.
Language	English
Publishing date	2024-03-15
Publishing country	India
Document type	Journal Article
ZDB-ID	218231-2
ISSN	0973-7693 ; 0019-5456
ISSN (online)	0973-7693
ISSN	0019-5456
DOI	10.1007/s12098-024-05078-1
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Article: To Study the Role of Perfusion Index as a Predictor of Hypotension during Spinal Anesthesia in Lower Segment Cesarean Section - A Prospective Observational Study.

Jabarulla, Reehana / Dhivya, D / Kumar, M S Prasanth

Anesthesia, essays and researches

2022 Volume 15, Issue 3, Page(s) 263–267

Abstract: Background and aims: Spinal anesthesia has become the choice of neuraxial anesthesia for cesarean delivery. Hypotension, the most common side effect of spinal anesthesia is more in parturients. Perfusion index (PI) is one of the newest methods, used ... ...

Abstract	Background and aims: Spinal anesthesia has become the choice of neuraxial anesthesia for cesarean delivery. Hypotension, the most common side effect of spinal anesthesia is more in parturients. Perfusion index (PI) is one of the newest methods, used noninvasively for the prediction of hypotension postspinal anesthesia, evaluation of regional block success, and a tool for pain assessment. In our study, we have used PI for predicting the occurrence of hypotension postsubarachnoid block in elective lower segment cesarean section (LSCS). Methods: In this prospective observational study, parturients posted for elective LSCS under spinal anesthesia were included. Spinal anesthesia was performed at L Statistical analysis used: Statistical analysis was performed using the paired sample Results: From our study, we had found that a positive correlation exists between the baseline PI of the patient and the occurrence of hypotension intraoperatively. A cutoff value of 1.75 (with Conclusion: Baseline perfusion of >1.75 can predict hypotension postspinal anesthesia in LSCS. The incidence of hypotension was about 93% in parturients whose baseline was above the cutoff value.
Language	English
Publishing date	2022-02-14
Publishing country	India
Document type	Journal Article
ZDB-ID	2626233-2
ISSN	2229-7685 ; 0259-1162
ISSN (online)	2229-7685
ISSN	0259-1162
DOI	10.4103/aer.aer_50_21
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Article ; Online: Prognostic values of SYNTAX score II in patients with coronary artery disease undergoing percutaneous coronary intervention - Cohort study.

Satheesh, Santhosh / Kumar, Ritesh / Pillai, Ajith Ananthakrishna / Selvaraj, Raja / Nair, Sreekumaran / Priya, Dhivya

Indian heart journal

2024

Abstract: Background: The data on prognostic values of SYNTAX score II in patients undergoing percutaneous coronary intervention is limited. We report predictive utility of SYNTAX score II in relation to in hospital and 1 year mortality of the patients undergoing ...

Abstract	Background: The data on prognostic values of SYNTAX score II in patients undergoing percutaneous coronary intervention is limited. We report predictive utility of SYNTAX score II in relation to in hospital and 1 year mortality of the patients undergoing percutaneous coronary intervention. Methods: This was a cohort study of patients who underwent percutaneous coronary intervention (PCI) at a single centre from January 2018 to December 2019. In hospital and 12-month events and mortality was analysed among 1000 patients. The patients were divided into 3 groups based on tertiles of Syntax II score (<22, 22-27.7 and >27.7). Result: The total mortality at 12 months was 60 (6%). Major adverse cardiac events (MACE) occurred in 87 (9%). The patients who died had higher SYNTAX score II score compared to those alive at 12 months 34 (38, 24) vs 24 (28.1, 20.9) P < 0.01. The same trend was seen in patients who had major adverse cardiac events (MACE) 28 (34, 24) vs 24 (28.6, 21) P < 0.01 Among the 3 groups of SYNTAX score II, in hospital mortality, all-cause mortality, cardiovascular death, myocardial infarction, unstable angina, revascularization and major adverse cardiac events (MACE) were higher in the third tertile (>27.7) compared the lower tertiles. Conclusion: The patients who had higher SYNTAX score II had more in hospital and 12 month mortality and major adverse cardiac events (MACE). SYNTAX II score is a better predictor of in-hospital, and 12 month cardiovascular and all cause mortality.
Language	English
Publishing date	2024-03-05
Publishing country	India
Document type	Journal Article
ZDB-ID	604366-5
ISSN	2213-3763 ; 0019-4832
ISSN (online)	2213-3763
ISSN	0019-4832
DOI	10.1016/j.ihj.2024.02.005
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Article ; Online: Hypersonic vitrectomy in intraoperative posterior capsular rupture with retained nuclear fragments.

Kumar, Dhivya Ashok / Agarwal, Amar / Agarwal, Ashvin / Papour, Asael

Indian journal of ophthalmology

2023 Volume 71, Issue 2, Page(s) 643–647

Abstract: In our report, we present the hypersonic vitrectomy (Vitesse, Bausch and Lomb) being employed for anterior vitreous liquefaction and removal in posterior capsular rupture. The capsular tear with nucleus drop during conventional phacoemulsification was ... ...

Abstract	In our report, we present the hypersonic vitrectomy (Vitesse, Bausch and Lomb) being employed for anterior vitreous liquefaction and removal in posterior capsular rupture. The capsular tear with nucleus drop during conventional phacoemulsification was managed by vitrectomy using the hypersonic vitrector after posterior-assisted levitation followed by intraocular lens (IOL) implantation. The minimal cortical and epinuclear lens particles in the anterior chamber and vitreous were also liquefied with a stoke length of 30 to 40 μm and aspirated via the Vitesse vitrectomy system. The same probe performs the vitrectomy and the nucleus removal. The postoperative period was uneventful with clear cornea, normal fundus, and 20/20 best-corrected visual acuity (BCVA). The hypersonic vitrectomy utilizes the ultrasound power of 29.5 kHz and a stoke length of 0 to 60 μm for liquefaction of the vitreous. It can be a safe alternative for vitrectomy and lens removal in a single setting.
MeSH term(s)	Humans ; Vitrectomy/adverse effects ; Cataract Extraction ; Lens, Crystalline ; Phacoemulsification/adverse effects ; Lens Implantation, Intraocular ; Rupture/surgery ; Intraoperative Complications ; Postoperative Complications ; Retrospective Studies
Language	English
Publishing date	2023-02-01
Publishing country	India
Document type	Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_1199_22
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Article ; Online: Intraocular lens power calculation changes before and after isotonic collagen cross-linking in keratoconus patients.

Namitha, V G / Kumar, Dhivya Ashok

Indian journal of ophthalmology

2021 Volume 70, Issue 1, Page(s) 114–117

Abstract: Purpose: To find the intraocular lens (IOL) power calculation changes before and after isotonic collagen cross-linking (CXL) in keratoconus patients.: Methods: : Thirty-five eyes of 25 patients who underwent isotonic CXL were included. The cases ... ...

Abstract	Purpose: To find the intraocular lens (IOL) power calculation changes before and after isotonic collagen cross-linking (CXL) in keratoconus patients. Methods: : Thirty-five eyes of 25 patients who underwent isotonic CXL were included. The cases included conventional CXL (n = 16), accelerated CXL (n = 7), contact lens-assisted CXL (CACXL) (n = 9), accelerated CACXL (n = 3). All underwent ocular biometry (IOL master), corneal topography (Orbscan II), and simulated keratometry (Orbscan II) preoperatively and 1-year post CXL. Change in best-corrected visual acuity (BCVA), axial length (AL), simulated keratometry (Sim K), anterior chamber depth (ACD), and IOL power were analyzed in the overall data and then grouped based on flattening (Group A) and no flattening (Group B) of Sim K value post CXL procedure. Results: For the overall data, there was no significant change in IOL power (P = 0.05) at the end of 1 year, BCVA showed a significant increase (P < 0.01), and Sim K reading showed a statistically significant flattening (P = 0.001); ACD and AL showed insignificant change. In intergroup comparison, there was no statistically significant change in IOL power. However, in Group A, a significant change in BCVA and Sim K values was observed. In both groups (Group A and Group B), IOL power was found to be negatively correlated with AL and Sim K values. Conclusion: Isotonic CXL did not affect IOL power calculation at the end of 1 year. However, significant change in BCVA and sim K reading was noted.
MeSH term(s)	Collagen/therapeutic use ; Corneal Topography ; Cross-Linking Reagents/therapeutic use ; Follow-Up Studies ; Humans ; Keratoconus/diagnosis ; Keratoconus/drug therapy ; Lenses, Intraocular ; Photochemotherapy ; Photosensitizing Agents/therapeutic use ; Riboflavin/therapeutic use ; Ultraviolet Rays ; Visual Acuity
Chemical Substances	Cross-Linking Reagents ; Photosensitizing Agents ; Collagen (9007-34-5) ; Riboflavin (TLM2976OFR)
Language	English
Publishing date	2021-12-24
Publishing country	India
Document type	Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_395_21
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Article ; Online: Outcomes of Pre-Descemet Endothelial Keratoplasty for Failed Therapeutic Penetrating Keratoplasty.

Narang, Priya / Ashok Kumar, Dhivya / Narang, Rhea / Agarwal, Amar

Cornea

2023

Abstract: Purpose: The aim of this study was to analyze the outcomes of pre-Descemet endothelial keratoplasty (PDEK) for failed therapeutic penetrating keratoplasty.: Methods: This was a retrospective, interventional study that involved 12 eyes of 12 patients ... ...

Abstract	Purpose: The aim of this study was to analyze the outcomes of pre-Descemet endothelial keratoplasty (PDEK) for failed therapeutic penetrating keratoplasty. Methods: This was a retrospective, interventional study that involved 12 eyes of 12 patients with failed therapeutic penetrating keratoplasty that underwent PDEK. All cases had a minimum follow-up of 12 months. The main outcome measures were best-corrected visual acuity, graft clarity, endothelial cell density loss, and graft survival. Corneal clarity was graded on a scale from 0 to 4, where grade 4 denoted an absolutely clear cornea and grade 0 denoted a totally opaque cornea. Three cases underwent PDEK, 6 cases PDEK with phacoemulsification, and 3 cases underwent PDEK with pupilloplasty. Results: The mean follow-up period for all cases was 18.5 ± 4.9 months. The mean preoperative and postoperative best-corrected visual acuity (in Snellen decimal equivalent) was 0.02 ± 0.01 and 0.54 ± 0.17, respectively, at the last follow-up. Postoperatively, corneal clarity grade 4 was present in 9 eyes, grade 3 in 2 eyes, and grade 2 in 1 eye. Mild subepithelial haze was noted in 2 eyes. The percentage of endothelial cell density loss was 28.2% ± 10.6%. No correlation was observed between the postoperative graft clarity and preoperative specular count (r = -0.021, P = 0.512). Rebubbling was performed for 1 eye that developed partial graft detachment in the first postoperative week. One patient had an episode of rejection that was managed with systemic and topical steroids. Conclusions: In patients with failed therapeutic penetrating keratoplasty, PDEK can be a useful alternative for visual rehabilitation as it demonstrates favorable visual outcomes with a good graft survival rate.
Language	English
Publishing date	2023-09-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	604826-2
ISSN	1536-4798 ; 0277-3740
ISSN (online)	1536-4798
ISSN	0277-3740
DOI	10.1097/ICO.0000000000003383
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Article ; Online: Reply.

Ashok Kumar, Dhivya / Agarwal, Amar

Eye & contact lens

2018 Volume 44 Suppl 1, Page(s) S375

Language	English
Publishing date	2018-09-12
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2103049-2
ISSN	1542-233X ; 1542-2321
ISSN (online)	1542-233X
ISSN	1542-2321
DOI	10.1097/ICL.0000000000000474
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