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  1. Article ; Online: Colloidal pathways of amorphous calcium carbonate formation lead to distinct water environments and conductivity.

    Gindele, Maxim B / Vinod-Kumar, Sanjay / Rochau, Johannes / Boemke, Daniel / Groß, Eduard / Redrouthu, Venkata SubbaRao / Gebauer, Denis / Mathies, Guinevere

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 80

    Abstract: ... ...

    Abstract CaCO
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-44381-x
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  2. Article ; Online: Topical oro-dispersible budesonide tablets for stricture prevention after near circumferential ESD for esophageal squamous cell cancer - a case report.

    Mathies, Daniel / Oyama, Tsuneo / Steinbrück, Ingo / Dumoulin, Franz Ludwig

    Zeitschrift fur Gastroenterologie

    2021  Volume 59, Issue 5, Page(s) 454–456

    Abstract: Background:  Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70-80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local ... ...

    Title translation Topische orodispersible Budesonid-Tablette zur Strikturprävention nach subtotal zirkumferentieller ESD eines Plattenepithelfrühkarzinoms im Ösophagus – Ein Fallbericht.
    Abstract Background:  Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70-80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local injections and/or systemic steroids are given for prevention.
    Case report:  We present here the case of a 78-year-old male patient who had a near circumferential endoscopic submucosal dissection for a pT1a mm, L0, V0, R0, G2 esophageal squamous cell cancer. At the end of endoscopic resection, 80 mg of triamcinolone was injected locally. The patient was then treated with oro-dispersible budesonide tablets (2 × 1 mg/day) and nystatin (4 × 100 000 I.E.) for 8 weeks. This treatment resulted in complete healing without any stricture formation and did not result in any complications.
    Discussion:  Treatment with orodispersible budesonide tablets could help prevent strictures after large endoscopic resections in the esophagus.
    MeSH term(s) Aged ; Budesonide/adverse effects ; Carcinoma, Squamous Cell/surgery ; Constriction, Pathologic ; Esophageal Neoplasms/surgery ; Esophageal Stenosis/chemically induced ; Esophageal Stenosis/prevention & control ; Esophagoscopy ; Humans ; Male ; Postoperative Complications ; Tablets
    Chemical Substances Tablets ; Budesonide (51333-22-3)
    Language English
    Publishing date 2021-03-18
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0172-8504 ; 0044-2771
    ISSN (online) 1439-7803
    ISSN 0172-8504 ; 0044-2771
    DOI 10.1055/a-1409-1076
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  3. Article ; Online: Colloidal pathways of amorphous calcium carbonate formation lead to distinct water environments and conductivity

    Maxim B. Gindele / Sanjay Vinod-Kumar / Johannes Rochau / Daniel Boemke / Eduard Groß / Venkata SubbaRao Redrouthu / Denis Gebauer / Guinevere Mathies

    Nature Communications, Vol 15, Iss 1, Pp 1-

    2024  Volume 14

    Abstract: Abstract CaCO3 is the most abundant biomineral and a major constituent of incrustations arising from water hardness. Polycarboxylates play key roles in controlling mineralization. Herein, we present an analytical and spectroscopic study of ... ...

    Abstract Abstract CaCO3 is the most abundant biomineral and a major constituent of incrustations arising from water hardness. Polycarboxylates play key roles in controlling mineralization. Herein, we present an analytical and spectroscopic study of polycarboxylate-stabilized amorphous CaCO3 (ACC) and its formation via a dense liquid precursor phase (DLP). Polycarboxylates facilitate pronounced, kinetic bicarbonate entrapment in the DLP. Since bicarbonate is destabilized in the solid state, DLP dehydration towards solid ACC necessitates the formation of locally calcium deficient sites, thereby inhibiting nucleation. Magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy of poly-aspartate-stabilized ACC reveals the presence of two distinct environments. The first contains immobile calcium and carbonate ions and structural water molecules, undergoing restricted, anisotropic motion. In the second environment, water molecules undergo slow, but isotropic motion. Indeed, conductive atomic force microscopy (C-AFM) reveals that ACC conducts electrical current, strongly suggesting that the mobile environment pervades the bulk of ACC, with dissolved hydroxide ions constituting the charge carriers. We propose that the distinct environments arise from colloidally stabilized interfaces of DLP nanodroplets, consistent with the pre-nucleation cluster (PNC) pathway.
    Keywords Science ; Q
    Subject code 541
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Femtosecond Stimulated Raman Spectroscopy.

    Dietze, Daniel R / Mathies, Richard A

    Chemphyschem : a European journal of chemical physics and physical chemistry

    2016  Volume 17, Issue 9, Page(s) 1224–1251

    Abstract: Femtosecond stimulated Raman spectroscopy (FSRS) is an ultrafast nonlinear optical technique that provides vibrational structural information with high temporal (sub-50 fs) precision and high spectral (10 cm(-1) ) resolution. Since the first full ... ...

    Abstract Femtosecond stimulated Raman spectroscopy (FSRS) is an ultrafast nonlinear optical technique that provides vibrational structural information with high temporal (sub-50 fs) precision and high spectral (10 cm(-1) ) resolution. Since the first full demonstration of its capabilities ≈15 years ago, FSRS has evolved into a mature technique, giving deep insights into chemical and biochemical reaction dynamics that would be inaccessible with any other technique. It is now being routinely applied to virtually all possible photochemical reactions and systems spanning from single molecules in solution to thin films, bulk crystals and macromolecular proteins. This review starts with an historic overview and discusses the theoretical and experimental concepts behind this technology. Emphasis is put on the current state-of-the-art experimental realization and several variations of FSRS that have been developed. The unique capabilities of FSRS are illustrated through a comprehensive presentation of experiments to date followed by prospects.
    MeSH term(s) Spectrum Analysis, Raman/methods ; Time Factors
    Language English
    Publishing date 2016--04
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1439-7641
    ISSN (online) 1439-7641
    DOI 10.1002/cphc.201600104
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  5. Article: A case of myocarditis after COVID-19 vaccination: incidental or consequential?

    Alizadeh, Leona S / Koch, Vitali / Yel, Ibrahim / Grünewald, Leon D / Mathies, Daniel / Martin, Simon / Vogl, Thomas J / Rauschning, Dominic / Booz, Christian

    Heliyon

    2022  Volume 8, Issue 6, Page(s) e09537

    Abstract: Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart ... ...

    Abstract Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart failure. We report a case of a 29-year-old man who presented with fever and retrosternal pain after receiving SARS-CoV-2 vaccine. Cardiac magnetic resonance imaging and laboratory data revealed typical findings of acute myocarditis.
    Language English
    Publishing date 2022-05-28
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e09537
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  6. Article: Case report of rare congenital cardiovascular anomalies associated with truncus arteriosus type 2.

    Alizadeh, Leona S / Koch, Vitali / Grünewald, Leon D / Yel, Ibrahim / Mathies, Daniel / Rauschning, Dominic / Vogl, Thomas J / Booz, Christian

    Heliyon

    2022  Volume 8, Issue 10, Page(s) e11033

    Abstract: Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to ...

    Abstract Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to be surgically treated. Thus, it is of high importance to understand this congenital cardiovascular disease and associated complications, to improve life expectancy and outcome of these patients. We recently came across a newborn female patient with a rare complex case of persistent TA type 2 associated with further complex cardiovascular anomalies, who received a contrast enhanced CT scan on the 3 rd day post-partum, showing complex cardiovascular abnormalities that were ultimately incompatible with life.
    Language English
    Publishing date 2022-10-12
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e11033
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  7. Article: Topical oro-dispersible budesonide tablets for stricture prevention after near circumferential ESD for esophageal squamous cell cancer – a case report

    Mathies, Daniel / Oyama, Tsuneo / Steinbrück, Ingo / Dumoulin, Franz Ludwig

    Zeitschrift für Gastroenterologie

    2021  Volume 59, Issue 05, Page(s) 454–456

    Abstract: Background: Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70–80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local ... ...

    Abstract Background: Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70–80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local injections and/or systemic steroids are given for prevention.
    Case report: We present here the case of a 78-year-old male patient who had a near circumferential endoscopic submucosal dissection for a pT1a mm, L0, V0, R0, G2 esophageal squamous cell cancer. At the end of endoscopic resection, 80 mg of triamcinolone was injected locally. The patient was then treated with oro-dispersible budesonide tablets (2 × 1 mg/day) and nystatin (4 × 100 000 I.E.) for 8 weeks. This treatment resulted in complete healing without any stricture formation and did not result in any complications.
    Discussion: Treatment with orodispersible budesonide tablets could help prevent strictures after large endoscopic resections in the esophagus.
    Keywords early esophageal cancer ; endoscopic submucosal dissection ; stricture prevention ; topical steroids budesonide ; Ösophagusfrühkarzinom ; endoskopische Submukosadissektion ; Prävention von Strikturen ; topische Steroide ; Budesonid
    Language English
    Publishing date 2021-03-18
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0044-2771 ; 0172-8504
    ISSN (online) 1439-7803
    ISSN 0044-2771 ; 0172-8504
    DOI 10.1055/a-1409-1076
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 111: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
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  8. Article ; Online: Case report of rare congenital cardiovascular anomalies associated with truncus arteriosus type 2

    Leona S. Alizadeh / Vitali Koch / Leon D. Grünewald / Ibrahim Yel / Daniel Mathies / Dominic Rauschning / Thomas J. Vogl / Christian Booz

    Heliyon, Vol 8, Iss 10, Pp e11033- (2022)

    2022  

    Abstract: Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to ...

    Abstract Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to be surgically treated. Thus, it is of high importance to understand this congenital cardiovascular disease and associated complications, to improve life expectancy and outcome of these patients. We recently came across a newborn female patient with a rare complex case of persistent TA type 2 associated with further complex cardiovascular anomalies, who received a contrast enhanced CT scan on the 3 rd day post-partum, showing complex cardiovascular abnormalities that were ultimately incompatible with life.
    Keywords Truncus arteriosus ; Fetal heart ; Cardiovascular diseases ; Heart defects ; Congenital ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 616
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: A case of Myocarditis after COVID-19 vaccination: Incidental or Consequential?

    Alizadeh, Leona S. / Koch, Vitali / Yel, Ibrahim / Grünewald, Leon D. / Mathies, Daniel / Martin, Simon / Vogl, Thomas J. / Rauschning, Dominic / Booz, Christian

    Heliyon. 2022 May 19,

    2022  

    Abstract: Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart ... ...

    Abstract Vaccination represents one of the fundamentals in the fight against SARS-CoV-2. Myocarditis has been reported as a rare but possible adverse consequence of different vaccines, and its clinical presentation can range from mild symptoms to acute heart failure. We report a case of a 29-year-old man who presented with fever and retrosternal pain after receiving SARS-CoV-2 vaccine. Cardiac magnetic resonance imaging and laboratory data revealed typical findings of acute myocarditis.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; fever ; heart failure ; magnetism ; myocarditis ; pain ; vaccination ; vaccines
    Language English
    Dates of publication 2022-0519
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e09537
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Case report of rare congenital cardiovascular anomalies associated with truncus arteriosus type 2

    Alizadeh, Leona S. / Koch, Vitali / Grünewald, Leon D. / Yel, Ibrahim / Mathies, Daniel / Rauschning, Dominic / Vogl, Thomas J. / Booz, Christian

    Heliyon. 2022 Oct., v. 8, no. 10 p.e11033-

    2022  

    Abstract: Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to ...

    Abstract Truncus arteriosus (TA) is a very rare congenital anomaly with complex cardiovascular anatomy and high lethality also due to severe associated anatomical variants and pathologies. As TA has a massive impact on the survival of a newborn and usually has to be surgically treated. Thus, it is of high importance to understand this congenital cardiovascular disease and associated complications, to improve life expectancy and outcome of these patients. We recently came across a newborn female patient with a rare complex case of persistent TA type 2 associated with further complex cardiovascular anomalies, who received a contrast enhanced CT scan on the 3 rd day post-partum, showing complex cardiovascular abnormalities that were ultimately incompatible with life.
    Keywords cardiovascular diseases ; case studies ; computed tomography ; congenital abnormalities ; death ; females ; longevity ; neonates ; patients ; Truncus arteriosus ; Fetal heart ; Heart defects ; Congenital
    Language English
    Dates of publication 2022-10
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e11033
    Database NAL-Catalogue (AGRICOLA)

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