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  1. Book: Ben cao gang mu xiao fang jin shi

    Li, Yi

    1986  

    Title translation Modern annotation on potent prescriptions listed in Pen ts'ao kang mu.
    Author's details Li I
    MeSH term(s) Drug Compounding ; Drug Prescriptions ; Medicine, Chinese Traditional
    Language Chinese
    Size 2, 2, 13, 506 p.
    Edition Di 1 ban.
    Publisher Shanxi ke xue jiao yu chu ban she
    Publishing place Taiyuan
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article ; Online: Xiao Jin Wan, a traditional Chinese herbal formula, inhibits proliferation via arresting cell cycle progression at the G2/M phase and promoting apoptosis via activating the mitochondrial‑dependent pathway in U-2OS human osteosarcoma cells.

    Wu, Guangwen / Chu, Jianfeng / Huang, Zhengrong / Ye, Jinxia / Chen, Panyu / Zheng, Chunsong / Li, Xihai / Liu, Xianxiang / Wu, Mingxia

    International journal of oncology

    2013  Volume 42, Issue 3, Page(s) 1070–1080

    Abstract: Xiao Jin Wan (XJW) is a well-known traditional Chinese folk-medicine, which is commonly used ... apoptosis, which may partly explain the anticancer activity of Xiao Jin Wan. ...

    Abstract Xiao Jin Wan (XJW) is a well-known traditional Chinese folk-medicine, which is commonly used for the treatment of various types of diseases including cancers. However, the mechanism of the anticancer activity of XJW against U-2OS human osteosarcoma cells, have not yet been reported. In the present study, we investigated the cellular effects of the XJW on the U-2OS human osteosarcoma cell line. Our results showed that XJW induced cell morphological changes, reduced cell viability in a dose- and time-dependent manner and arrested in the G2/M phase of the cell cycle suggesting that XJW inhibited the proliferation of U-2OS cells. Hoechst 33258 staining and Annexin V/propidium iodide double staining exhibited the typical nuclear features of apoptosis and increased the proportion of apoptotic Annexin V-positive cells in a dose-dependent manner, respectively. In addition, XJW treatment caused loss of plasma membrane asymmetry, collapse of mitochondrial membrane potential, activation of caspase-9 and caspase-3, and increase of the ratio of pro-apoptotic Bax to anti-apoptotic Bcl-2. Taken together, the results indicate that the U-2OS cell growth inhibitory activity of XJW was due to cell cycle arrested and mitochondrial-mediated apoptosis, which may partly explain the anticancer activity of Xiao Jin Wan.
    MeSH term(s) Apoptosis/drug effects ; Apoptosis Regulatory Proteins/metabolism ; Bone Neoplasms/drug therapy ; Bone Neoplasms/metabolism ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drugs, Chinese Herbal/pharmacology ; Enzyme Activation ; G2 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Osteosarcoma/drug therapy ; Osteosarcoma/metabolism ; Phytotherapy ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism
    Chemical Substances Apoptosis Regulatory Proteins ; Drugs, Chinese Herbal ; Proto-Oncogene Proteins c-bcl-2 ; bcl-2-Associated X Protein ; Caspase 3 (EC 3.4.22.-) ; Caspase 9 (EC 3.4.22.-)
    Language English
    Publishing date 2013-03
    Publishing country Greece
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1154403-x
    ISSN 1791-2423 ; 1019-6439
    ISSN (online) 1791-2423
    ISSN 1019-6439
    DOI 10.3892/ijo.2013.1795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Gan dan ji bing gu jin xiao fang

    Li, Xiru

    1999  

    Title translation Effective prescribed recipes from ancient to modern for liver and biliary tract diseases.
    Author's details Li Xiru zhu bian
    MeSH term(s) Liver Diseases/drug therapy ; Biliary Tract Diseases/drug therapy ; Drugs, Chinese Herbal/therapeutic use
    Language Chinese
    Size v, 466 p.
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030070012 ; 7030070011
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Book: Fu ke ji bing gu jin xiao fang

    Li, Xiru

    1998  

    Title translation Effective prescribed recipes from ancient to modern for gynecological diseases.
    Author's details Li Xiru zhu bian
    MeSH term(s) Genital Diseases, Female/drug therapy ; Drugs, Chinese Herbal/therapeutic use ; Medicine, Chinese Traditional
    Language Chinese
    Size vi, 404 p.
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030068569 ; 7030068564
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Book: Wei chang ji bing gu jin xiao fang

    Li, Xiru

    1998  

    Title translation Effective prescribed recipes from ancient to modern for gastrointestinal diseases.
    Author's details Li Xiru zhu bian
    MeSH term(s) Gastrointestinal Diseases/drug therapy ; Drugs, Chinese Herbal/therapeutic use ; Medicine, Chinese Traditional
    Language Chinese
    Size vi, 452 p.
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030064141 ; 7030064143
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Book: Shen jing jing shen ji bing gu jin xiao fang

    Li, Xiru

    1998  

    Title translation Effective prescribed recipes from ancient to modern for nervous diseases and mental disorders.
    Author's details zhu bian Li Xiru
    MeSH term(s) Nervous System Diseases/drug therapy ; Mental Disorders/drug therapy ; Drugs, chinese herbal/therapeutic use
    Language Chinese
    Size vii, 807 p.
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030065193 ; 7030065190
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Book: Tou mian ji bing gu jin xiao fang

    Li, Xiru

    1998  

    Title translation Effective prescribed recipes from ancient to modern for brain diseases and diseases of the sense organs.
    Author's details Li Xiru zhu bian
    MeSH term(s) Brain Diseases/drug therapy ; Drugs, Chinese Herbal/therapeutic use ; Sense Organs/physiology
    Language Chinese
    Size vii, 798 p.
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030066008 ; 7030066006
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Book: Pi fu ke ji bing gu jin xiao fang

    Li, Xiru

    1998  

    Title translation Ancient and modern effective therapeutic recipes for skin diseases.
    Author's details Li Xiru zhu bian
    MeSH term(s) Skin Diseases/drug therapy ; Materia Medica ; Medicine, Chinese Traditional
    Language Chinese
    Size ii, 481 p.
    Edition Di 1 ban.
    Publisher Kexue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030063793 ; 7030063791
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article ; Online: A New HPLC-UV Method Using Hydrolyzation with Sodium Hydroxide for Quantitation of

    Lu, Shi-Hui / Liang, Xiao-Na / Nong, Xiao-Jin / Chen, Ran / Li, Xiu-Xia

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 14

    Abstract: ... ...

    Abstract Trans
    MeSH term(s) Ligustrum ; Sodium Hydroxide ; Chromatography, High Pressure Liquid/methods ; Esters ; Plant Extracts ; Plant Leaves
    Chemical Substances p-coumaric acid (IBS9D1EU3J) ; Sodium Hydroxide (55X04QC32I) ; Esters ; Plant Extracts
    Language English
    Publishing date 2023-07-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28145309
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acetylenic spiroketal enol ethers from

    Xiao, Chuan-Yun / Lan, Jiang-Er / Liu, Xiao / Sun, Zhong-Lin / Li, Xiao-Jin / Yin, Yi-Han / Gibbons, Simon / Mu, Qing

    Natural product research

    2023  Volume 38, Issue 4, Page(s) 589–593

    Abstract: Synergistic bioassay-guided isolation of the extracts ... ...

    Abstract Synergistic bioassay-guided isolation of the extracts of
    MeSH term(s) Methicillin-Resistant Staphylococcus aureus ; Molecular Docking Simulation ; Acetylene/metabolism ; Acetylene/pharmacology ; Alkynes/pharmacology ; Ethers/metabolism ; Ethers/pharmacology ; Artemisia ; Plant Extracts/chemistry ; Anti-Bacterial Agents ; Oxacillin/pharmacology ; Oxacillin/metabolism ; Microbial Sensitivity Tests ; Drug Synergism ; Furans ; Spiro Compounds
    Chemical Substances spiroketal ; Acetylene (OC7TV75O83) ; Alkynes ; Ethers ; Plant Extracts ; Anti-Bacterial Agents ; Oxacillin (UH95VD7V76) ; Furans ; Spiro Compounds
    Language English
    Publishing date 2023-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2183952
    Database MEDical Literature Analysis and Retrieval System OnLINE

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