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  1. Article ; Online: Letter to the Editor re: Genetic Testing of Pilot Applicants: Response.

    Hwan Shin, Seung

    Aerospace medicine and human performance

    2020  Volume 91, Issue 6, Page(s) 536

    MeSH term(s) Genetic Testing
    Language English
    Publishing date 2020-05-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2809085-8
    ISSN 2375-6322 ; 2375-6314
    ISSN (online) 2375-6322
    ISSN 2375-6314
    DOI 10.3357/AMHP.5596.2020
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  2. Article ; Online: Letter to the Editor re: Genetic Testing of Pilot Applicants: Letters.

    Hwan Shin, Seung

    Aerospace medicine and human performance

    2020  Volume 91, Issue 6, Page(s) 536

    MeSH term(s) Body Composition ; Genetic Testing ; Genotype ; Personnel Selection
    Language English
    Publishing date 2020-05-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2809085-8
    ISSN 2375-6322 ; 2375-6314
    ISSN (online) 2375-6322
    ISSN 2375-6314
    DOI 10.3357/AMHP.5596.2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tailored Band Alignment for Improved Carrier Transport in Composition-Controlled Sb

    Lim, Geumha / Park, Ha Kyung / Wang, Yazi / Ji, Seung Hwan / Shin, Byungha / Jo, William

    The journal of physical chemistry letters

    2024  Volume 15, Issue 10, Page(s) 2825–2833

    Abstract: ... ...

    Abstract Sb
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.4c00257
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  4. Article ; Online: Congruent Concavity Restoration of the Reconstructed Glenoid After the Latarjet Procedure: Compensation for the Position of the Graft.

    Do, Woo-Sung / Shin, Seung-Hwan / Lim, Joon-Ryul / Yoon, Tae-Hwan / Chun, Yong-Min

    The Journal of bone and joint surgery. American volume

    2024  Volume 106, Issue 5, Page(s) 407–413

    Abstract: Background: Few clinical studies have addressed concavity restoration by natural remodeling after a Latarjet procedure. This study investigated the fibrous tissue and osseous remodeling of the reconstructed glenoid and concavity restoration after a ... ...

    Abstract Background: Few clinical studies have addressed concavity restoration by natural remodeling after a Latarjet procedure. This study investigated the fibrous tissue and osseous remodeling of the reconstructed glenoid and concavity restoration after a Latarjet procedure using postoperative computed tomographic arthrography (CTA).
    Methods: This retrospective study included 31 patients who underwent immediate postoperative computed tomographic (CT) scanning followed by CTA at 6 months postoperatively. We investigated whether fibrous tissue was newly created over the graft, whether the created fibrous tissue restored the congruity of the articular surface and the osseous remodeling of the graft to the glenoid level (whether the osseous portion of the graft was remodeled flush to the glenoid level) and the concavity of the glenoid using the radius of a best-fit circle on the articular surface, and the relationship between the amount of created fibrous tissue and the position of the graft.
    Results: In all patients, the fibrous tissue on the graft yielded a smooth articular surface, as revealed by the CTA. The mean radius of the entire glenoid, including the transferred graft, was significantly smaller (p = 0.010) at 33.2 ± 8.5 mm than that of the glenoid posterior to the osseous step-off at 37.6 ± 9.4 mm, which is presumed to be the glenoid before the surgical procedure. Despite the congruity of the articular surfaces due to fibrous tissue seen in the CTA, 14 (45%) of 31 patients showed a subchondral osseous step-off on either the medial side or the lateral side in the immediate postoperative CT scans. However, through osseous remodeling, 8 of the 10 grafts with a lateral step-off and 2 of the 4 grafts with a medial step-off converted to a flush position. The position of the step-off was correlated with the thickness of the fibrous tissue, with a tendency for thicker tissue in cases of a step-off on the medial side (p = 0.014).
    Conclusions: Fibrous tissue formation plus remodeling of the transferred graft resulted in the restoration of a congruent concavity after a Latarjet procedure by compensating for initially non-flush positioning of the graft. However, due to the small sample size in our study, clinical outcomes could not be correlated with radiographic findings, and our recommendation is to continue placing the graft as anatomically as possible.
    Level of evidence: Therapeutic Level IV . See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Humans ; Shoulder Joint/diagnostic imaging ; Shoulder Joint/surgery ; Retrospective Studies ; Joint Instability/surgery ; Scapula/surgery ; Arthroplasty/methods ; Bone Transplantation/methods
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.23.00510
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    Zs.MO 464: Show issues

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  5. Article: Appreciation and recognition of the contributions of authors and peer reviewers in 2023.

    Park, Jun-Beom / Park, Shin-Young / Park, Jung-Chul / Kim, Yong-Gun / Ahn, Hwan Tae / Shin, Seung-Yun

    Journal of periodontal & implant science

    2024  Volume 54, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2024-02-25
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2557339-1
    ISSN 2093-2286 ; 2093-2278
    ISSN (online) 2093-2286
    ISSN 2093-2278
    DOI 10.5051/jpis.245401edi01
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  6. Article: Revolutionizing scholarly publishing by integrating artificial intelligence into editorial and peer review processes.

    Park, Jun-Beom / Park, Shin-Young / Park, Jung-Chul / Kim, Yong-Gun / Ahn, Hwan Tae / Shin, Seung-Yun

    Journal of periodontal & implant science

    2024  Volume 54, Issue 2, Page(s) 63–64

    Language English
    Publishing date 2024-04-24
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2557339-1
    ISSN 2093-2286 ; 2093-2278
    ISSN (online) 2093-2286
    ISSN 2093-2278
    DOI 10.5051/jpis.245402edi01
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  7. Article ; Online: [Viral Hepatitis in Patients with Inflammatory Bowel Disease].

    Shin, Seung Hwan / Park, Sang Hyoung

    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

    2022  Volume 80, Issue 2, Page(s) 51–59

    Abstract: There has been a rise in the incidence of inflammatory bowel disease (IBD) in developing countries, including South Korea. Consequently, the use of immunosuppressive agents such as immunomodulators or biologics has also increased. Due to ... ...

    Abstract There has been a rise in the incidence of inflammatory bowel disease (IBD) in developing countries, including South Korea. Consequently, the use of immunosuppressive agents such as immunomodulators or biologics has also increased. Due to immunosuppression, patients on these agents are at increased risk of various opportunistic infections during treatment, which may sometimes lead to serious adverse outcomes. Viral hepatitis, especially hepatitis B, is one of the infectious conditions that can be reactivated during immunosuppressive therapy, and adequate strategies for monitoring and prophylaxis are needed to prevent it. South Korea is one of the countries with intermediate endemicity for hepatitis A and B. Thus, taking adequate precautions against viral hepatitis could prevent new infections or reactivation of these conditions in patients with IBD on immunosuppressive therapy. In this review article, we have summarized the latest evidence on viral hepatitis in patients with IBD that would be of assistance in clinical practice.
    MeSH term(s) Hepatitis B/complications ; Hepatitis, Viral, Human/complications ; Hepatitis, Viral, Human/diagnosis ; Humans ; Immunosuppressive Agents/adverse effects ; Inflammatory Bowel Diseases/chemically induced ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/drug therapy ; Republic of Korea
    Chemical Substances Immunosuppressive Agents
    Language Korean
    Publishing date 2022-08-25
    Publishing country Korea (South)
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2611091-X
    ISSN 2233-6869 ; 1598-9992
    ISSN (online) 2233-6869
    ISSN 1598-9992
    DOI 10.4166/kjg.2022.096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Toxoplasma gondii IST suppresses inflammatory and apoptotic responses by inhibiting STAT1-mediated signaling in IFN-γ/TNF-α-stimulated hepatocytes.

    Seo, Seung-Hwan / Lee, Ji-Eun / Ham, Do-Won / Shin, Eun-Hee

    Parasites, hosts and diseases

    2024  Volume 62, Issue 1, Page(s) 30–41

    Abstract: The dense granule protein of Toxoplasma gondii, inhibitor of signal transducer and activator of transcription 1 (IST) is an inhibitor of signal transducer and activator of transcription 1 (STAT1) transcriptional activity that binds to STAT1 and regulates ...

    Abstract The dense granule protein of Toxoplasma gondii, inhibitor of signal transducer and activator of transcription 1 (IST) is an inhibitor of signal transducer and activator of transcription 1 (STAT1) transcriptional activity that binds to STAT1 and regulates the expression of inflammatory molecules in host cells. A sterile inflammatory liver injury in pathological acute liver failures occurs when excessive innate immune function, such as the massive release of IFN-γ and TNF-α, is activated without infection. In relation to inflammatory liver injury, we hypothesized that Toxoplasma gondii inhibitor of STAT1 transcription (TgIST) can inhibit the inflammatory response induced by activating the STAT1/IRF-1 mechanism in liver inflammation. This study used IFN-γ and TNF-α as inflammatory inducers at the cellular level of murine hepatocytes (Hepa-1c1c7) to determine whether TgIST inhibits the STAT1/IRF-1 axis. In stable cells transfected with TgIST, STAT1 expression decreased with a decrease in interferon regulatory factor (IRF)-1 levels. Furthermore, STAT1 inhibition of TgIST resulted in lower levels of NF-κB and COX2, as well as significantly lower levels of class II transactivator (CIITA), iNOS, and chemokines (CLXCL9/10/11). TgIST also significantly reduced the expression of hepatocyte proapoptotic markers (Caspase3/8/9, P53, and BAX), which are linked to sterile inflammatory liver injury. TgIST also reduced the expression of adhesion (ICAM-1 and VCAM-1) and infiltration markers of programmed death-ligand 1 (PD-L1) induced by hepatocyte and tissue damage. TgIST restored the cell apoptosis induced by IFN-γ/TNF-α stimulation. These results suggest that TgIST can inhibit STAT1-mediated inflammatory and apoptotic responses in hepatocytes stimulated with proinflammatory cytokines.
    MeSH term(s) Animals ; Mice ; Tumor Necrosis Factor-alpha ; Toxoplasma ; STAT1 Transcription Factor/genetics ; Hepatocytes ; Signal Transduction
    Chemical Substances Tumor Necrosis Factor-alpha ; STAT1 Transcription Factor
    Language English
    Publishing date 2024-02-23
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2982-6799
    ISSN (online) 2982-6799
    DOI 10.3347/PHD.23129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Investigation of the Long-Term Effects of Amantadine Use in Parkinson's Disease.

    Park, Sangmin / Shin, Jung Hwan / Jeon, Seung Ho / Lee, Chan Young / Kim, Han-Joon / Jeon, Beomseok

    Journal of movement disorders

    2023  Volume 16, Issue 2, Page(s) 224–226

    Language English
    Publishing date 2023-05-24
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3021788-X
    ISSN 2093-4939 ; 2005-940X
    ISSN (online) 2093-4939
    ISSN 2005-940X
    DOI 10.14802/jmd.23037
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  10. Article ; Online: Impact of National Public-Private Mix and Medical Expense Support Program for Control Tuberculosis in South Korea: An Interrupted Time Series Analysis.

    Oh, In-Sun / Kim, Ju Hwan / Huh, Kyungmin / Jang, Seung Hun / Shin, Ju-Young

    The Journal of infectious diseases

    2024  

    Abstract: Tuberculosis (TB) remains a major threat to global public health, various measures at national level have been implemented to control TB and no evidence with long-term effectiveness has yet been evaluated on TB control programs. We confirmed the long- ... ...

    Abstract Tuberculosis (TB) remains a major threat to global public health, various measures at national level have been implemented to control TB and no evidence with long-term effectiveness has yet been evaluated on TB control programs. We confirmed the long-term effectiveness of the TB control programs in reducing overall burden in South Korea using interrupted time series analysis. Along with the Public-Private Mix, our finding suggests that relieving the economic burden of people with TB may further complement in achieving the End TB strategy. For countries currently developing strategies for TB control, results may provide important insights in effective TB control.
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiae059
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    Zs.MO 445: Show issues

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