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Article ; Online: Association between COVID-19 vaccination and relapse of glomerulonephritis.

Ota, Yuki / Kuroki, Ryoma / Iwata, Mayu / Taira, Hiroshi / Matsuo, Sayumi / Kamijo, Masafumi / Muta, Kumiko / Nishino, Tomoya

Clinical and experimental nephrology

2022 Volume 27, Issue 3, Page(s) 236–242

Abstract: Background: Vaccines for coronavirus disease 2019 (COVID-19) have been developed and are recommended for patients with chronic kidney disease; however, it has been reported that glomerulonephritis worsens after vaccination. We aimed to elucidate the ... ...

Abstract	Background: Vaccines for coronavirus disease 2019 (COVID-19) have been developed and are recommended for patients with chronic kidney disease; however, it has been reported that glomerulonephritis worsens after vaccination. We aimed to elucidate the incidence and association between COVID-19 vaccination and glomerulonephritis relapse. Methods: We investigated the onset of renal events and adverse reactions after COVID-19 vaccination in 111 patients diagnosed with glomerulonephritis. Renal events were defined as worsening hematuria, increased proteinuria, and an increased creatine level over 1.5-fold from baseline. Results: Patients were 57 ± 18 years old (55.9% female) and had an estimated glomerular filtration rate of 57.0 ± 25.0 ml/min/1.73 m Conclusions: COVID-19 vaccination and glomerulonephritis relapse may be related, but further research is needed.
MeSH term(s)	Humans ; Female ; Adult ; Middle Aged ; Aged ; Male ; Glomerulonephritis, IGA/pathology ; COVID-19 Vaccines/adverse effects ; Hematuria/epidemiology ; Hematuria/etiology ; Hematuria/pathology ; BNT162 Vaccine ; COVID-19/epidemiology ; COVID-19/prevention & control ; Glomerulonephritis/epidemiology ; Glomerulonephritis/pathology ; Proteinuria/epidemiology ; Proteinuria/etiology ; Proteinuria/pathology ; Chronic Disease ; Vaccination
Chemical Substances	COVID-19 Vaccines ; BNT162 Vaccine
Language	English
Publishing date	2022-11-23
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1338768-6
ISSN	1437-7799 ; 1342-1751
ISSN (online)	1437-7799
ISSN	1342-1751
DOI	10.1007/s10157-022-02299-6
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Zs.A 4922: Show issues

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Article ; Online: Transradial Mechanical Thrombectomy Using a Radial-specific Neurointerventional Guiding Sheath for Anterior Circulation Large-Vessel Occlusions: Preliminary Experience and Literature Review.

Kuroiwa, Masafumi / Hanaoka, Yoshiki / Koyama, Jun-Ichi / Yamazaki, Daisuke / Kubota, Yuki / Kitamura, Satoshi / Ichinose, Shunsuke / Nakamura, Takuya / Kamijo, Takaaki / Fujii, Yu / Ogiwara, Toshihiro / Murata, Takahiro / Horiuchi, Tetsuyoshi

World neurosurgery

2022 Volume 171, Page(s) e581–e589

Abstract: Background: Transradial mechanical thrombectomy (MT) is increasingly used because it is associated with a low incidence of vascular access site complications. However, transradial carotid cannulation can be technically challenging to perform in patients ...

Abstract	Background: Transradial mechanical thrombectomy (MT) is increasingly used because it is associated with a low incidence of vascular access site complications. However, transradial carotid cannulation can be technically challenging to perform in patients with an unfavorable supra-aortic takeoff. In this study, the feasibility and safety of a new transradial MT system with a radial-specific neurointerventional guiding sheath-6F Simmons guiding sheath was evaluated-in patients with anterior circulation large-vessel occlusions. Additionally, a literature review was performed. Methods: We retrospectively analyzed data from our institutional database about consecutive patients who underwent transradial MT for anterior circulation large-vessel occlusion. After the 6F Simmons guiding sheath was engaged into the target common carotid artery, a triaxial system (Simmons guiding sheath/aspiration catheter/microcatheter), was established. MT using the continuous aspiration prior to intracranial vascular embolectomy technique was performed. Then, procedural success rate, successful revascularization, and procedure-related complications were assessed. Results: A total of 13 patients who had transradial MT were included in the analysis. All 13 patients underwent successful thrombectomy without catheter kinking or system instability, and 12 of them achieved successful revascularization (modified Thrombolysis in Cerebral Infarction score of ≥2b). No complications occurred. Conclusions: To the best of our knowledge, this is the first case series on transradial MT using a radial-specific neurointerventional system for anterior circulation large-vessel occlusions. This method may increase the success rate of transradial MT. Based on our initial experience, transradial MT, using this system, was feasible and safe for anterior circulation large-vessel occlusions.
MeSH term(s)	Humans ; Retrospective Studies ; Treatment Outcome ; Thrombectomy/methods ; Carotid Artery, Common ; Radial Artery ; Stroke/etiology
Language	English
Publishing date	2022-12-15
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2022.12.060
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Zs.A 1159: Show issues

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Article ; Online: Executive summary: Japanese guidelines for allergic rhinitis 2020.

Okano, Mitsuhiro / Fujieda, Shigeharu / Gotoh, Minoru / Kurono, Yuichi / Matsubara, Atsushi / Ohta, Nobuo / Kamijo, Atsushi / Yamada, Takechiyo / Nakamaru, Yuji / Asako, Mikiya / Sakurai, Daiju / Terada, Tetsuya / Yonekura, Shuji / Sakashita, Masafumi / Okubo, Kimihiro

Allergology international : official journal of the Japanese Society of Allergology

2022 Volume 72, Issue 1, Page(s) 41–53

Abstract: The Practical Guideline for the Management of Allergic Rhinitis, the fist guideline for allergic rhinitis in Japan, was prepared after a symposium held by the Japanese Society of Allergology in 1993. The current 9th edition was published in 2020 and is ... ...

Abstract	The Practical Guideline for the Management of Allergic Rhinitis, the fist guideline for allergic rhinitis in Japan, was prepared after a symposium held by the Japanese Society of Allergology in 1993. The current 9th edition was published in 2020 and is widely used today. The most recent collection of evidence from the literature was supplemented to the revised guideline to incorporate evidence-based medicine. The revised guideline includes updated epidemiology of allergic rhinitis in Japan, a figure representing the mechanisms of allergic rhinitis in both the onset and sensitization phases with the introduction of regulatory T cells and type 2 innate lymphoid cells, practical assessment for diagnosis, new pharmacotherapy agents such as anti-IgE mAb and a new drug delivery system for antihistamines, sublingual immunotherapy for children, dual sublingual immunotherapy for house dust mites and Japanese cedar pollen extract, new classification for surgery for allergic rhinitis, and treatment and prescriptions for older adults. An evidence-based step-by-step strategy for treatment is also described.
MeSH term(s)	Child ; Animals ; Humans ; Aged ; Immunity, Innate ; Lymphocytes ; Rhinitis, Allergic/diagnosis ; Rhinitis, Allergic/epidemiology ; Rhinitis, Allergic/therapy ; Allergens ; Pyroglyphidae
Chemical Substances	Allergens
Language	English
Publishing date	2022-12-09
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1336498-4
ISSN	1440-1592 ; 1323-8930
ISSN (online)	1440-1592
ISSN	1323-8930
DOI	10.1016/j.alit.2022.11.003
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Zs.A 5248: Show issues

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Article ; Online: Endovascular therapy for hemodialysis patients with atrial fibrillation and cerebral thromboembolism: A case series.

Kamijo, Masafumi / Hayashi, Waka / Otsuka, Emiko / Obata, Yoko / Sahara, Noriyuki / Takemoto, Koichiro / Sakamoto, Seisaburo / Ueki, Yukitaka / Nishino, Tomoya

The International journal of artificial organs

2019 Volume 43, Issue 3, Page(s) 150–156

Abstract: Introduction: Hemodialysis patients with atrial fibrillation are at high risk for stroke. Intravenous recombinant tissue plasminogen activator is considered for acute ischemic stroke. However, recombinant tissue plasminogen activator therapy is ... ...

Abstract	Introduction: Hemodialysis patients with atrial fibrillation are at high risk for stroke. Intravenous recombinant tissue plasminogen activator is considered for acute ischemic stroke. However, recombinant tissue plasminogen activator therapy is contraindicated for some hemodialysis patients with atrial fibrillation. These patients and those who have received recombinant tissue plasminogen activator therapy without blood flow recovery are candidates for endovascular therapy. Methods and results: Three hemodialysis patients with atrial fibrillation received endovascular therapy for acute cerebral infarction. Cerebrovascular incident occurred during or after hemodialysis in two of these patients. All three patients achieved successful recanalization after endovascular therapy. Conclusion: In this series, endovascular therapy showed good results without complications. More cases should be investigated to obtain more evidence of successful endovascular therapy for hemodialysis patients.
MeSH term(s)	Administration, Intravenous ; Aged ; Atrial Fibrillation/complications ; Endovascular Procedures/methods ; Female ; Fibrinolytic Agents/administration & dosage ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Male ; Renal Dialysis/adverse effects ; Renal Dialysis/methods ; Stroke/diagnosis ; Stroke/etiology ; Stroke/surgery ; Thrombolytic Therapy/methods ; Tissue Plasminogen Activator/administration & dosage ; Treatment Outcome
Chemical Substances	Fibrinolytic Agents ; Tissue Plasminogen Activator (EC 3.4.21.68)
Language	English
Publishing date	2019-10-17
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80456-3
ISSN	1724-6040 ; 0391-3988
ISSN (online)	1724-6040
ISSN	0391-3988
DOI	10.1177/0391398819882018
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Zs.A 1439: Show issues

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Article ; Online: Hyperleukocytosis Complicated by Intracerebral Hemorrhage and Spurious Hypoxemia: A Case Report and Literature Review.

Katakura, Yumi / Yamaguchi, Yoshikazu / Miyashita, Tetsuya / Idei, Masafumi / Yoshida, Tasuku / Matsuda, Yuko / Takaki, Shunsuke / Kamijo, Aki / Yamaguchi, Osamu / Goto, Takahisa

A & A case reports

2017 Volume 9, Issue 6, Page(s) 159–161

Abstract: We present the management of a 15-year-old girl with acute myeloid leukemia who presented with massive hyperleukocytosis and neurological deficit due to intracerebral hemorrhage. Surgical intervention was considered but ultimately not undertaken because ... ...

Abstract	We present the management of a 15-year-old girl with acute myeloid leukemia who presented with massive hyperleukocytosis and neurological deficit due to intracerebral hemorrhage. Surgical intervention was considered but ultimately not undertaken because of the presence of massive hyperleukocytosis, thrombocytopenia, hypokalemia, and considerable discrepancy between the oxygen saturation values determined mechanically and by peripheral oximetry. Aggressive treatment of the hyperleukocytosis was immediately started, which improved the patient's overall condition and rendered surgical intervention unnecessary. This report shows that immediate treatment of massive hyperleukocytosis and critical interpretation of laboratory results in patients with hyperleukocytosis are warranted.
Language	English
Publishing date	2017-09-15
Publishing country	United States
Document type	Journal Article
ISSN	2325-7237
ISSN (online)	2325-7237
DOI	10.1213/XAA.0000000000000553
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Article: A case of mild phenotype Alport syndrome caused by COL4A3 mutations.

Kamijo, Masafumi / Kitamura, Mineaki / Muta, Kumiko / Uramatsu, Tadashi / Obata, Yoko / Nozu, Kandai / Kaito, Hiroshi / Iijima, Kazumoto / Mukae, Hiroshi / Nishino, Tomoya

CEN case reports

2017 Volume 6, Issue 2, Page(s) 189–193

Abstract: In a case of 41-year-old man with mild nephropathy, Alport syndrome (AS) was diagnosed from the renal biopsy. However, the α5 chain of type IV collagen expressed in the glomerular basement membrane, which was the atypical staining pattern of AS. Genetic ... ...

Abstract	In a case of 41-year-old man with mild nephropathy, Alport syndrome (AS) was diagnosed from the renal biopsy. However, the α5 chain of type IV collagen expressed in the glomerular basement membrane, which was the atypical staining pattern of AS. Genetic testing suggested autosomal recessive AS from heterozygous mutations at two positions in the type IV collagen α3 chain. These two gene mutations represented a new pattern of mutation and was suggested the association with an atypical α5 chain expression and mild phenotype.
Language	English
Publishing date	2017-08-30
Publishing country	Japan
Document type	Journal Article
ISSN	2192-4449
ISSN	2192-4449
DOI	10.1007/s13730-017-0273-2
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Article: Oxygen-radical pretreatment promotes cellulose degradation by cellulolytic enzymes.

Sakai, Kiyota / Kojiya, Saki / Kamijo, Junya / Tanaka, Yuta / Tanaka, Kenta / Maebayashi, Masahiro / Oh, Jun-Seok / Ito, Masafumi / Hori, Masaru / Shimizu, Motoyuki / Kato, Masashi

Biotechnology for biofuels

2017 Volume 10, Page(s) 290

Abstract: Background: The efficiency of cellulolytic enzymes is important in industrial biorefinery processes, including biofuel production. Chemical methods, such as alkali pretreatment, have been extensively studied and demonstrated as effective for breaking ... ...

Abstract	Background: The efficiency of cellulolytic enzymes is important in industrial biorefinery processes, including biofuel production. Chemical methods, such as alkali pretreatment, have been extensively studied and demonstrated as effective for breaking recalcitrant lignocellulose structures. However, these methods have a detrimental effect on the environment. In addition, utilization of these chemicals requires alkali- or acid-resistant equipment and a neutralization step. Results: Here, a radical generator based on non-thermal atmospheric pressure plasma technology was developed and tested to determine whether oxygen-radical pretreatment enhances cellulolytic activity. Our results showed that the viscosity of carboxymethyl cellulose (CMC) solutions was reduced in a time-dependent manner by oxygen-radical pretreatment using the radical generator. Compared with non-pretreated CMC, oxygen-radical pretreatment of CMC significantly increased the production of reducing sugars in culture supernatant containing various cellulases from Conclusions: Oxygen-radical pretreatment of CMC and wheat straw enhanced the degradation of cellulose by reducing- and non-reducing-end cellulases in the supernatant of a culture of the white-rot fungus
Language	English
Publishing date	2017-12-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2421351-2
ISSN	1754-6834
ISSN	1754-6834
DOI	10.1186/s13068-017-0979-6
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Article ; Online: CFC1 is a cancer stemness-regulating factor in neuroblastoma.

Chikaraishi, Koji / Takenobu, Hisanori / Sugino, Ryuichi P / Mukae, Kyosuke / Akter, Jesmin / Haruta, Masayuki / Kurosumi, Masafumi / Endo, Takaho A / Koseki, Haruhiko / Shimojo, Naoki / Ohira, Miki / Kamijo, Takehiko

Oncotarget

2017 Volume 8, Issue 28, Page(s) 45046–45059

Abstract: Background: Despite the use of aggressive therapy, survival rates among high-risk neuroblastoma (NB) patients remain poor. Cancer stem cells (CSCs) are considered to be critically involved in the recurrence and metastasis of NB and are isolated as NB ... ...

Abstract	Background: Despite the use of aggressive therapy, survival rates among high-risk neuroblastoma (NB) patients remain poor. Cancer stem cells (CSCs) are considered to be critically involved in the recurrence and metastasis of NB and are isolated as NB spheres. Methods: The gene expression profiling of adherent (control) and sphere-forming primary NB cells was conducted using a gene expression microarray. CFC1, which functions in the development of embryos and decides the left-right axis, was strongly expressed in sphere-forming cells only and was related to the unfavorable prognosis of NB patients. The knockdown and overexpression of CFC1 were performed using a lentiviral system in NB cell lines. Sphere formation, cell proliferation, colony formation in soft agar, and xenograft tumor formation were analyzed. Results: The overexpression of CFC1 increased sphere formation, cell growth, and colony formation. These phenotypes, particularly sphere formation, and xenograft tumor formation were significantly suppressed by the knockdown of CFC1. CFC1 inhibited Activin A-induced NB cell differentiation and Smad2 phosphorylation in NB cell lines, indicating its involvement in tumorigenesis related to EGF-CFC co-receptor family molecule pathways. Collectively, these results indicate that CFC1 is a candidate molecule for the development of CSC-targeted therapy for NB.
Language	English
Publishing date	2017-07-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2560162-3
ISSN	1949-2553 ; 1949-2553
ISSN (online)	1949-2553
ISSN	1949-2553
DOI	10.18632/oncotarget.18464
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Article: [Sharing information of urological cancer patient in terminal stage using Cybozulive® for home medical care].

Yumura, Yasushi / Hattori, Yusuke / Gobara, Ayako / Takamoto, Daiji / Yasuda, Kengo / Nakamura, Masafumi / Noguchi, Kazumi / Asahina, Kan / Kamijo, Takeo

Hinyokika kiyo. Acta urologica Japonica

2014 Volume 60, Issue 9, Page(s) 421–426

Abstract: It is very important to share patient information because home patient care involves several different specialties of care. We introduced Cybozulive ® , a cloud-based free groupware, for 14 terminal-stage patients with urological cancer to share ... ...

Abstract	It is very important to share patient information because home patient care involves several different specialties of care. We introduced Cybozulive ® , a cloud-based free groupware, for 14 terminal-stage patients with urological cancer to share information among doctors and co-medical staff. This system enables access to patient information regardless of time and place. Of the 14 patients (mean age 74.4 years), 11 died of cancer. The average period in which Cybozulive® was used for the patients was 210 days. The average number of entries to the electronic bulletin board in this period was 88.4. We were able to obtain more information about the patients from the website. There was no difference in the average number of times that the patient consulted the out patient clinic before and after the introduction of Cybozulive® (before 7.0 after 6.3). After introduction of this system, eleven patients were hospitalized in our department 21 times. Eighteen of these 21 times, since we had acquired patient information from the website beforehand, there was a quick response for management of the emergency admission. This system could be used to construct a network for home care and may be helpful for sharing patient information in homecare.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Home Care Services ; Humans ; Internet ; Middle Aged ; Patient Care Team ; Terminal Care ; Urologic Neoplasms/therapy
Language	Japanese
Publishing date	2014-09
Publishing country	Japan
Document type	English Abstract ; Journal Article
ZDB-ID	604331-8
ISSN	0018-1994
ISSN	0018-1994
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Zs.A 411: Show issues

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Article: Oxygen-radical pretreatment promotes cellulose degradation by cellulolytic enzymes

Sakai, Kiyota / Kojiya, Saki / Kamijo, Junya / Tanaka, Yuta / Tanaka, Kenta / Maebayashi, Masahiro / Oh, Jun-Seok / Ito, Masafumi / Hori, Masaru / Shimizu, Motoyuki / Kato, Masashi

Biotechnology for biofuels. 2017 Dec., v. 10, no. 1

2017

Abstract: BACKGROUND: The efficiency of cellulolytic enzymes is important in industrial biorefinery processes, including biofuel production. Chemical methods, such as alkali pretreatment, have been extensively studied and demonstrated as effective for breaking ... ...

Abstract	BACKGROUND: The efficiency of cellulolytic enzymes is important in industrial biorefinery processes, including biofuel production. Chemical methods, such as alkali pretreatment, have been extensively studied and demonstrated as effective for breaking recalcitrant lignocellulose structures. However, these methods have a detrimental effect on the environment. In addition, utilization of these chemicals requires alkali- or acid-resistant equipment and a neutralization step. RESULTS: Here, a radical generator based on non-thermal atmospheric pressure plasma technology was developed and tested to determine whether oxygen-radical pretreatment enhances cellulolytic activity. Our results showed that the viscosity of carboxymethyl cellulose (CMC) solutions was reduced in a time-dependent manner by oxygen-radical pretreatment using the radical generator. Compared with non-pretreated CMC, oxygen-radical pretreatment of CMC significantly increased the production of reducing sugars in culture supernatant containing various cellulases from Phanerochaete chrysosporium. The production of reducing sugar from oxygen-radical-pretreated CMC by commercially available cellobiohydrolases I and II was 1.7- and 1.6-fold higher, respectively, than those from non-pretreated and oxygen-gas-pretreated CMC. Moreover, the amount of reducing sugar from oxygen-radical-pretreated wheat straw was 1.8-fold larger than those from non-pretreated and oxygen-gas-pretreated wheat straw. CONCLUSIONS: Oxygen-radical pretreatment of CMC and wheat straw enhanced the degradation of cellulose by reducing- and non-reducing-end cellulases in the supernatant of a culture of the white-rot fungus P. chrysosporium. These findings indicated that oxygen-radical pretreatment of plant biomass offers great promise for improvements in lignocellulose-deconstruction processes.
Keywords	Phanerochaete chrysosporium ; acid tolerance ; alkali treatment ; atmospheric pressure ; biorefining ; carboxymethylcellulose ; cellulases ; equipment ; fuel production ; lignocellulose ; neutralization ; phytomass ; reactive oxygen species ; reducing sugars ; viscosity ; wheat straw ; white-rot fungi
Language	English
Dates of publication	2017-12
Size	p. 290.
Publishing place	BioMed Central
Document type	Article
ZDB-ID	2421351-2
ISSN	1754-6834
ISSN	1754-6834
DOI	10.1186/s13068-017-0979-6
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