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  1. Article ; Online: A case of Elschnig's spots observed using optical coherence tomography-angiography after stenting for internal carotid artery dissection.

    Saito, Kazuma / Uchida, Yuto / Tokui, Shunsuke / Akiyama, Hideo

    Retinal cases & brief reports

    2023  

    Abstract: Purpose: We report the case of a 28-year-old man who developed Elschnig's spots after stenting for an internal carotid artery dissection using optical coherence tomography angiography (OCTA).: Methods: A case report.: Results: The patient ... ...

    Abstract Purpose: We report the case of a 28-year-old man who developed Elschnig's spots after stenting for an internal carotid artery dissection using optical coherence tomography angiography (OCTA).
    Methods: A case report.
    Results: The patient developed a visual field defect in the left eye immediately after endovascular stenting for left internal carotid artery dissection. Fundus examination revealed white lesions and numerous mottled orange-red lesions in the posterior pole and mid-periphery of the left eye. Indocyanine green angiography revealed mottled hypofluorescein areas in the early and late stages, coinciding with the orange-red lesions. OCTA showed flow void areas in the choriocapillaris layer, consistent with the orange-red lesions, which were diagnosed as Elschnig's spots associated with choroidal circulatory failure. The spots disappeared approximately 2 months after surgery, and the flow void on OCTA also disappeared.
    Conclusion: We report a case of Elschnig's spots associated with transient choroidal circulatory failure after stenting for internal carotid artery dissection. OCTA detected improved circulation at the level of the choriocapillaris with the disappearance of Elschnig's spots.
    Language English
    Publishing date 2023-09-19
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001496
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sensing Algorithm to Estimate Slight Displacement and Posture Change of Target from Monocular Images.

    Ito, Tadashi / Yoneyama, Hiroo / Akiyama, Yuto / Hagiwara, Tomonori / Ezawa, Shunsuke

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 2

    Abstract: Various types of displacement sensors, which measure position changes of object, have been developed depending on the type and shape of the object under measurement, measurement range of the amount of displacement, required accuracy, and application. We ... ...

    Abstract Various types of displacement sensors, which measure position changes of object, have been developed depending on the type and shape of the object under measurement, measurement range of the amount of displacement, required accuracy, and application. We are developing a new type of displacement sensor that is image-based, capable of measuring changes in 6DOF (3D position and orientation) of an object simultaneously, and is compact and low-cost. This displacement sensor measures the 6DOF of an object using images obtained by a monocular vision system. To confirm the usefulness of the proposed method, experimental measurements were conducted using a simple and inexpensive optical system. In this experiment, we were able to accurately measure changes of about 0.25 mm in displacement and 0.1 deg in inclination of the object at a distance of a few centimeters, and thus confirming the usefulness of the proposed method.
    MeSH term(s) Algorithms ; Optical Devices ; Posture
    Language English
    Publishing date 2023-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23020851
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  3. Article ; Online: Radial Branch Artery Pseudoaneurysm.

    Sawano, Toyoaki / Akiyama, Yuto

    Radiology

    2020  Volume 295, Issue 2, Page(s) 274

    MeSH term(s) Aged ; Aneurysm, False/diagnostic imaging ; Aneurysm, False/surgery ; Animals ; Bites and Stings ; Cats ; Computed Tomography Angiography ; Contrast Media ; Female ; Humans ; Radial Artery/diagnostic imaging ; Radial Artery/injuries ; Radial Artery/surgery
    Chemical Substances Contrast Media
    Language English
    Publishing date 2020-02-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2019191819
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    Ue I Zs.106: Show issues Location:
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  4. Article ; Online: Polyelectrolyte/Gold Nanoparticle Nanotubes Incorporating Doxorubicin-Loaded Liposomes.

    Enomoto, Yuto / Akiyama, Motofusa / Morita, Yoshitsugu / Komatsu, Teruyuki

    Chemistry, an Asian journal

    2021  Volume 16, Issue 24, Page(s) 4057–4061

    Abstract: Anticancer agent doxorubicin-loaded liposomes (DoxLs) were drawn spontaneously into nanotubes comprising multilayers of polyelectrolytes and gold nanoparticles (PAuNTs). We describe a unique structure of PAuNTs incorporating DoxLs (DoxL-PAuNT). The ... ...

    Abstract Anticancer agent doxorubicin-loaded liposomes (DoxLs) were drawn spontaneously into nanotubes comprising multilayers of polyelectrolytes and gold nanoparticles (PAuNTs). We describe a unique structure of PAuNTs incorporating DoxLs (DoxL-PAuNT). The number of DoxLs adsorbed on the tube interior surface was ascertained as 2.4×10
    MeSH term(s) Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cell Survival/drug effects ; Doxorubicin/chemistry ; Doxorubicin/pharmacology ; Drug Carriers/chemistry ; Drug Liberation ; Gold/chemistry ; HeLa Cells ; Humans ; Liposomes/chemistry ; Metal Nanoparticles/chemistry ; Nanotubes/chemistry ; Polyelectrolytes/chemistry ; Temperature
    Chemical Substances Antineoplastic Agents ; Drug Carriers ; Liposomes ; Polyelectrolytes ; Gold (7440-57-5) ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2021-10-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202101109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Native Myocardial T1 Value in Predicting 1-Year Outcomes in Patients with Nonischemic Dilated Cardiomyopathy Experiencing Recent Heart Failure.

    Kitagawa, Toshiro / Tatsugami, Fuminari / Yokomachi, Kazushi / Akiyama, Yuji / Fujii, Yuto / Awai, Kazuo / Nakano, Yukiko

    International heart journal

    2022  Volume 63, Issue 3, Page(s) 531–540

    Abstract: The evidence for the clinical implications, especially the short-term utility, of native myocardial T1 value ( ... ...

    Abstract The evidence for the clinical implications, especially the short-term utility, of native myocardial T1 value (T1
    MeSH term(s) Arrhythmias, Cardiac ; Cardiomyopathy, Dilated/complications ; Contrast Media ; Gadolinium ; Heart Failure/diagnosis ; Humans ; Magnetic Resonance Imaging, Cine/methods ; Myocardium ; Ventricular Remodeling
    Chemical Substances Contrast Media ; Gadolinium (AU0V1LM3JT)
    Language English
    Publishing date 2022-06-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2187806-7
    ISSN 1349-3299 ; 1349-2365
    ISSN (online) 1349-3299
    ISSN 1349-2365
    DOI 10.1536/ihj.21-801
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 211: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article ; Online: Cardiac reprogramming reduces inflammatory macrophages and improves cardiac function in chronic myocardial infarction.

    Abe, Yuto / Tani, Hidenori / Sadahiro, Taketaro / Yamada, Yu / Akiyama, Tatsuya / Nakano, Koji / Honda, Seiichiro / Ko, Seien / Anzai, Atsushi / Ieda, Masaki

    Biochemical and biophysical research communications

    2023  Volume 690, Page(s) 149272

    Abstract: Cardiomyocytes (CMs) have little regenerative capacity. After myocardial infarction (MI), scar formation and myocardial remodeling proceed in the infarct and non-infarct areas, respectively, leading to heart failure (HF). Prolonged activation of cardiac ... ...

    Abstract Cardiomyocytes (CMs) have little regenerative capacity. After myocardial infarction (MI), scar formation and myocardial remodeling proceed in the infarct and non-infarct areas, respectively, leading to heart failure (HF). Prolonged activation of cardiac fibroblasts (CFs) and inflammatory cells may contribute to this process; however, therapies targeting these cell types remain lacking. Cardiac reprogramming converts CFs into induced CMs, reduces fibrosis, and improves cardiac function in chronic MI through the overexpression of Mef2c/Gata4/Tbx5/Hand2 (MGTH). However, whether cardiac reprogramming reduces inflammation in infarcted hearts remains unclear. Moreover, the mechanism through which MGTH overexpression in CFs affects inflammatory cells remains unknown. Here, we showed that inflammation persists in the myocardium until three months after MI, which can be reversed with cardiac reprogramming. Single-cell RNA sequencing demonstrated that CFs expressed pro-inflammatory genes and exhibited strong intercellular communication with inflammatory cells, including macrophages, in chronic MI. Cardiac reprogramming suppressed the inflammatory profiles of CFs and reduced the relative ratios and pro-inflammatory signatures of cardiac macrophages. Moreover, fluorescence-activated cell sorting analysis (FACS) revealed that cardiac reprogramming reduced the number of chemokine receptor type 2 (CCR2)-positive inflammatory macrophages in the non-infarct areas in chronic MI, thereby restoring myocardial remodeling. Thus, cardiac reprogramming reduced the number of inflammatory macrophages to exacerbate cardiac function after MI.
    MeSH term(s) Humans ; Myocardial Infarction/metabolism ; Myocardium/metabolism ; Myocytes, Cardiac/metabolism ; Macrophages/metabolism ; Inflammation/metabolism ; Fibroblasts/metabolism
    Language English
    Publishing date 2023-11-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.149272
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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  7. Article: Significant Enhancement of Piezoelectric Response in AlN by Yb Addition.

    Hirata, Kenji / Mori, Yuto / Yamada, Hiroshi / Uehara, Masato / Anggraini, Sri Ayu / Akiyama, Morito

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 2

    Abstract: This study employs first-principles calculations to investigate how introducing Yb into aluminum nitride (AlN) leads to a large enhancement in the material's piezoelectric response ( ...

    Abstract This study employs first-principles calculations to investigate how introducing Yb into aluminum nitride (AlN) leads to a large enhancement in the material's piezoelectric response (
    Language English
    Publishing date 2021-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14020309
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  8. Article ; Online: Chronic spinal epidural abscess in a cat: a case report with an unusual imaging finding.

    Miki, Shingo / Akiyama Yamashita, Kyoko / Kanzaki Okamoto, Mei / Iwanaga, Yuto / Fukuda, Shoko / Mashita, Tadahisa

    The Journal of veterinary medical science

    2021  Volume 84, Issue 1, Page(s) 69–73

    Abstract: A 1-year-old domestic shorthair cat was evaluated for a chronic history of back pain, dysuria, and paraplegia. Radiographic and computed tomographic examinations showed circumferential widening of the vertebral canal at T13 and T14. A spinal epidural ... ...

    Abstract A 1-year-old domestic shorthair cat was evaluated for a chronic history of back pain, dysuria, and paraplegia. Radiographic and computed tomographic examinations showed circumferential widening of the vertebral canal at T13 and T14. A spinal epidural abscess (SEA) compressing the spinal cord from the level of T11 to L1 was suspected following intravenous contrast administration, and was confirmed by surgical exploration and histopathological analysis. The cat recovered its motor and bladder functions following surgical decompression and antibiotic therapy. SEA is a neurological emergency requiring prompt treatment. However, the present case had a prolonged disease course and pressure atrophy of the vertebrae was strongly suspected. To our knowledge, this imaging finding has not been reported in dogs or cats with SEA.
    MeSH term(s) Animals ; Cat Diseases/diagnostic imaging ; Cats ; Epidural Abscess/diagnostic imaging ; Epidural Abscess/veterinary ; Paraplegia/veterinary ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-11-29
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 1071753-5
    ISSN 1347-7439 ; 0916-7250
    ISSN (online) 1347-7439
    ISSN 0916-7250
    DOI 10.1292/jvms.21-0462
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    Zs.B 579: Show issues Location:
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  9. Article ; Online: Ultraflexible Wireless Imager Integrated with Organic Circuits for Broadband Infrared Thermal Analysis.

    Kawabata, Rei / Li, Kou / Araki, Teppei / Akiyama, Mihoko / Sugimachi, Kaho / Matsuoka, Nozomi / Takahashi, Norika / Sakai, Daiki / Matsuzaki, Yuto / Koshimizu, Ryo / Yamamoto, Minami / Takai, Leo / Odawara, Ryoga / Abe, Takaaki / Izumi, Shintaro / Kurihira, Naoko / Uemura, Takafumi / Kawano, Yukio / Sekitani, Tsuyoshi

    Advanced materials (Deerfield Beach, Fla.)

    2024  Volume 36, Issue 15, Page(s) e2309864

    Abstract: Flexible imagers are currently under intensive development as versatile optical sensor arrays, designed to capture images of surfaces and internals, irrespective of their shape. A significant challenge in developing flexible imagers is extending their ... ...

    Abstract Flexible imagers are currently under intensive development as versatile optical sensor arrays, designed to capture images of surfaces and internals, irrespective of their shape. A significant challenge in developing flexible imagers is extending their detection capabilities to encompass a broad spectrum of infrared light, particularly terahertz (THz) light at room temperature. This advancement is crucial for thermal and biochemical applications. In this study, a flexible infrared imager is designed using uncooled carbon nanotube (CNT) sensors and organic circuits. The CNT sensors, fabricated on ultrathin 2.4 µm substrates, demonstrate enhanced sensitivity across a wide infrared range, spanning from near-infrared to THz wavelengths. Moreover, they retain their characteristics under bending and crumpling. The design incorporates light-shielded organic transistors and circuits, functioning reliably under light irradiation, and amplifies THz detection signals by a factor of 10. The integration of both CNT sensors and shielded organic transistors into an 8 × 8 active-sensor matrix within the imager enables sequential infrared imaging and nondestructive assessment for heat sources and in-liquid chemicals through wireless communication systems. The proposed imager, offering unique functionality, shows promise for applications in biochemical analysis and soft robotics.
    Language English
    Publishing date 2024-01-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202309864
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  10. Article ; Online: Chiral Magnesium Bisphosphate-Catalyzed Asymmetric Double C(sp

    Mori, Keiji / Isogai, Ryo / Kamei, Yuto / Yamanaka, Masahiro / Akiyama, Takahiko

    Journal of the American Chemical Society

    2018  Volume 140, Issue 20, Page(s) 6203–6207

    Abstract: Described herein is a chiral magnesium bisphosphate-catalyzed asymmetric double C( ... ...

    Abstract Described herein is a chiral magnesium bisphosphate-catalyzed asymmetric double C(sp
    Language English
    Publishing date 2018--23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.8b02761
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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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