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  1. Book ; Online: Peng Cheng Object Detection Benchmark for Smart City

    Wang, Yaowei / Yang, Zhouxin / Liu, Rui / Li, Deng / Lai, Yuandu / Fang, Leyuan / Han, Yahong

    2022  

    Abstract: Object detection is an algorithm that recognizes and locates the objects in the image and has a wide range of applications in the visual understanding of complex urban scenes. Existing object detection benchmarks mainly focus on a single specific ... ...

    Abstract Object detection is an algorithm that recognizes and locates the objects in the image and has a wide range of applications in the visual understanding of complex urban scenes. Existing object detection benchmarks mainly focus on a single specific scenario and their annotation attributes are not rich enough, these make the object detection model is not generalized for the smart city scenes. Considering the diversity and complexity of scenes in intelligent city governance, we build a large-scale object detection benchmark for the smart city. Our benchmark contains about 500K images and includes three scenarios: intelligent transportation, intelligent security, and drones. For the complexity of the real scene in the smart city, the diversity of weather, occlusion, and other complex environment diversity attributes of the images in the three scenes are annotated. The characteristics of the benchmark are analyzed and extensive experiments of the current state-of-the-art target detection algorithm are conducted based on our benchmark to show their performance.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2022-03-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Efficient Expression and Characterization of an Endo-Type Lyase HCLase_M28 and Its Gradual Scale-Up Fermentation for the Preparation of Chondroitin Sulfate Oligosaccharides.

    Ju, Ruibao / Han, Baoqin / Han, Feng / Peng, Yanfei

    Applied biochemistry and biotechnology

    2024  

    Abstract: Glycosaminoglycan (GAG) lyases have been critical in structural and functional studies of GAGs. HCLase_M28, a lyase identified from the genome of Microbacterium sp. M28 was heterologously expressed, enzymatically characterized, and prepared in large- ... ...

    Abstract Glycosaminoglycan (GAG) lyases have been critical in structural and functional studies of GAGs. HCLase_M28, a lyase identified from the genome of Microbacterium sp. M28 was heterologously expressed, enzymatically characterized, and prepared in large-scale fermentation for the production of chondroitin sulfate (CS) oligosaccharides. Results showed that the expression of HCLase_M28 in Escherichia coli BL21 (DE3)-pET24a-HCLase_M28
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392344-7
    ISSN 1559-0291 ; 0273-2289
    ISSN (online) 1559-0291
    ISSN 0273-2289
    DOI 10.1007/s12010-024-04878-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3053: Show issues Location:
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  3. Article ; Online: A novel Peng's test in reducing bile leakage after partial hepatectomy for hepatocellular carcinoma: From an animal study to a clinical cohort Propensity score matching comparative study.

    Mo, Shutian / He, Yongfei / Zhu, Guangzhi / Su, Hao / Han, Chuangye / Ye, Xinping / Liao, Xiwen / Yang, Chengkun / Liang, Tianyi / Chen, Zijun / Wei, Yongguang / Wei, Zhongliu / Luo, Jianzhu / Nong, Jusen / Lau, Wan Yee / Peng, Tao

    International journal of surgery (London, England)

    2022  Volume 104, Page(s) 106748

    Abstract: ... detection approach (Peng's test) was developed in a swine model to determine the pressures generated ... on a prospective cohort of patients using Peng's test versus a retrospective historical cohort patient group using ... in the CBD of 85.3 ± 9.5 cmH: Conclusion: Peng's test for intraoperative BL detection is safe and ...

    Abstract Background: Bile leakage (BL) is a common complication of partial hepatectomy for hepatocellular carcinoma (HCC). However, various intraoperative approaches to detect BL have not been widely accepted owing to uncertainty in their treatment effectiveness and complexity of use.
    Materials and methods: A novel BL-detection approach (Peng's test) was developed in a swine model to determine the pressures generated in the gallbladder and common bile duct (CBD) during the test. A comparative study was then conducted on a prospective cohort of patients using Peng's test versus a retrospective historical cohort patient group using the White Gauze test in partial hepatectomy for HCC. Propensity score matching (PSM) was performed in a 1:1 ratio to balance confounding factors.
    Results: The maximum pressures with methylene blue injection in the gallbladder and CBD without Pringle's maneuver in the four swines were 103.8 ± 11.8 and 42.3 ± 6.1, respectively. After Pringle's maneuver, 32.0 ± 6.8 mL methylene blue injection led to a maximum pressure in the CBD of 85.3 ± 9.5 cmH
    Conclusion: Peng's test for intraoperative BL detection is safe and effective in reducing BL after hepatectomy.
    MeSH term(s) Animals ; Bile ; Biliary Tract Diseases ; Carcinoma, Hepatocellular ; Hepatectomy ; Humans ; Liver Neoplasms ; Methylene Blue ; Propensity Score ; Prospective Studies ; Retrospective Studies ; Swine
    Chemical Substances Methylene Blue (T42P99266K)
    Language English
    Publishing date 2022-07-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2022.106748
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  4. Article ; Online: Correction: The association between ADAM12 gene polymorphisms and osteoarthritis: an updated meta-analysis.

    Yang, Su / Wang, Yue-Peng / Li, Xi-Yong / Han, Peng-Yong / Han, Peng-Fei

    Journal of orthopaedic surgery and research

    2023  Volume 18, Issue 1, Page(s) 240

    Language English
    Publishing date 2023-03-25
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2252548-8
    ISSN 1749-799X ; 1749-799X
    ISSN (online) 1749-799X
    ISSN 1749-799X
    DOI 10.1186/s13018-023-03685-w
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  5. Article: Regulated cell death in glioma: promising targets for natural small-molecule compounds.

    Han, Mingyu / Li, Sui / Fan, Huali / An, Junsha / Peng, Cheng / Peng, Fu

    Frontiers in oncology

    2024  Volume 14, Page(s) 1273841

    Abstract: Gliomas are prevalent malignant tumors in adults, which can be categorized as either localized or diffuse gliomas. Glioblastoma is the most aggressive and deadliest form of glioma. Currently, there is no complete cure, and the median survival time is ... ...

    Abstract Gliomas are prevalent malignant tumors in adults, which can be categorized as either localized or diffuse gliomas. Glioblastoma is the most aggressive and deadliest form of glioma. Currently, there is no complete cure, and the median survival time is less than one year. The main mechanism of regulated cell death involves organisms coordinating the elimination of damaged cells at risk of tumor transformation or cells hijacked by microorganisms for pathogen replication. This process includes apoptosis, necroptosis, autophagy, ferroptosis, pyroptosis, necrosis, parthanayosis, entosis, lysosome-dependent death, NETosis, oxiptosis, alkaliptosis, and disulfidaptosis. The main goal of clinical oncology is to develop therapies that promote the effective elimination of cancer cells by regulating cell death are the main goal of clinical oncology. Recently, scientists have utilized pertinent regulatory factors and natural small-molecule compounds to induce regulated cell death for the treatment of gliomas. By analyzing the PubMed and Web of Science databases, this paper reviews the research progress on the regulation of cell death and the role of natural small-molecule compounds in glioma. The aim is to provide help for the treatment of glioblastoma.
    Language English
    Publishing date 2024-01-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1273841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Metabolic, toxicological, chemical, and commercial perspectives on esterification of dietary polyphenols: a review.

    Peng, Han / Shahidi, Fereidoon

    Critical reviews in food science and nutrition

    2023  , Page(s) 1–40

    Abstract: Molecular modifications have been practiced for more than a century and nowadays they are widely applied in food, pharmaceutical, or other industries to manipulate the physicochemical, bioactivity, metabolic/catabolic, and pharmacokinetic properties. ... ...

    Abstract Molecular modifications have been practiced for more than a century and nowadays they are widely applied in food, pharmaceutical, or other industries to manipulate the physicochemical, bioactivity, metabolic/catabolic, and pharmacokinetic properties. Among various structural modifications, the esterification/
    Language English
    Publishing date 2023-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2023.2185589
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1459: Show issues Location:
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  7. Article ; Online: C1QBP is a critical component in the immune response of large yellow croaker (Larimichthys crocea) against visceral white spot disease caused by Pseudomonas plecoglossicida.

    Peng, Jia / Zhang, Sen / Han, Fang / Wang, Zhiyong

    Fish & shellfish immunology

    2024  Volume 146, Page(s) 109372

    Abstract: The large yellow croaker (Larimichthys crocea) stands as a cornerstone of mariculture in China due to its significant value. However, the threat of Pseudomonas plecoglossicida infection looms large, capable of triggering "visceral white spot disease" and ...

    Abstract The large yellow croaker (Larimichthys crocea) stands as a cornerstone of mariculture in China due to its significant value. However, the threat of Pseudomonas plecoglossicida infection looms large, capable of triggering "visceral white spot disease" and subsequently inflicting severe economic ramifications. Through a prior genome-wide association analysis (GWAS) aimed at understanding the resistance of the large yellow croaker to this ailment, a pivotal player emerged: the complement component 1q binding protein, aptly named LcC1qbp. This protein assumes a crucial role in the activation of the complement system. This study delves deeper into the immune response by examining the expression patterns of LcC1QBP when confronted with P. plecoglossicida. The investigation into gene expression patterns reveals LcC1qbp's widespread presence, with its highest transcriptional abundance identified in the kidney tissues. Upon infection by P. plecoglossicida, the up-regulation of LcC1qbp in major immune organs manifests at both the transcriptional and translational levels. In the context of RNA interference, transcriptome analysis of C1qbp in HEK 293T cells uncovers 1327 differentially expressed genes (DEGs), featuring 41 significant immune genes. This includes pivotal components such as C1S and C3 of the complement system, along with IL11, IL12RB2, and Myd88, among others. The outcomes of enrichment analysis spotlight the prevalence of DEGs within key pathways like immune system development, myeloid leukocyte-mediated immunity, MAPK signaling, and other immune-related routes. By unveiling the immune response mechanisms of the large yellow croaker to P. plecoglossicida infection, this study bolsters our understanding. Furthermore, it lays the groundwork for pursuing effective strategies in both preventing and treating "visceral white spot disease" in the large yellow croaker.
    MeSH term(s) Animals ; Genome-Wide Association Study ; Pseudomonas/genetics ; Pseudomonas Infections ; Immunity ; Perciformes/genetics ; Fish Proteins/genetics ; Fish Diseases
    Chemical Substances Fish Proteins
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1067738-0
    ISSN 1095-9947 ; 1050-4648
    ISSN (online) 1095-9947
    ISSN 1050-4648
    DOI 10.1016/j.fsi.2024.109372
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  8. Article ; Online: Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.

    Huang, Yongkai / Wu, Zhihui / Peng, Zewei / Liu, Anmin / Yuan, Wen / Han, Deqing / Peng, Junmin

    BMC cancer

    2024  Volume 24, Issue 1, Page(s) 345

    Abstract: Background: Meningioma, the most prevalent intracranial tumor, possesses a significant propensity for malignant transformation. Circular RNAs (circ-RNAs), a class of non-coding RNAs, have emerged as crucial players in tumorigenesis. This study explores ... ...

    Abstract Background: Meningioma, the most prevalent intracranial tumor, possesses a significant propensity for malignant transformation. Circular RNAs (circ-RNAs), a class of non-coding RNAs, have emerged as crucial players in tumorigenesis. This study explores the functional relevance of hsa_circ_0004872, a specific circ-RNA, in the context of meningioma.
    Methods: Molecular structure and stability of hsa_circ_0004872 were elucidated through PCR identification. Meningioma cell proliferation and apoptosis were assessed using the CCK-8 assay and flow cytometry, respectively. Gene and protein expression were analyzed via qRT-PCR and western blot. Molecular interactions were confirmed through dual-luciferase reporter gene and RIP assays.
    Results: Hsa_circ_0004872, derived from exons 2 to 4 of the host gene MAPK1, demonstrated enhanced stability compared to its host MAPK1. Clinical data described that hsa_circ_0004872 was reduced in meningioma tissues and cell lines, and negatively correlated to poor survival rate of meningioma patients. Overexpression of hsa_circ_0004872 exhibited inhibitory effects on cell proliferation and promotion of apoptosis in vitro. Subsequent investigations unveiled a direct interaction between hsa_circ_0004872 and miR-190a-3p, leading to the activation of the PI3K/AKT signaling pathway through targeting PTEN. Notably, miR-190a-3p silence accelerated the apoptosis and proliferation inhibition of meningioma cells by inactivating PTEN/PI3K/AKT signaling, while miR-190a-3p overexpression showed an opposite effect, which greatly reversed the anti-tumor effects of hsa_circ_0004872 overexpression.
    Conclusion: In summary, our findings highlighted the intricate role of hsa_circ_0004872 in meningioma, shedding light on the regulatory mechanisms involving circ-RNAs in tumor progression. This positions hsa_circ_0004872 as a potential key regulatory factor in meningioma with implications for future therapeutic interventions.
    MeSH term(s) Humans ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation/genetics ; Cell Transformation, Neoplastic ; Gene Expression Regulation, Neoplastic ; Meningeal Neoplasms/genetics ; Meningioma/genetics ; MicroRNAs/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins c-akt/genetics ; PTEN Phosphohydrolase/genetics ; Signal Transduction/genetics
    Chemical Substances MicroRNAs ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; PTEN Phosphohydrolase (EC 3.1.3.67) ; PTEN protein, human (EC 3.1.3.67) ; MIRN190 microRNA, human
    Language English
    Publishing date 2024-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-024-12084-1
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  9. Article ; Online: A commentary on 'ChatGPT in medicine: prospects and challenges: a review article'.

    Han, Yupeng / Wu, Haixing / Ke, Peng / Wu, Xiaodan

    International journal of surgery (London, England)

    2024  

    Language English
    Publishing date 2024-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000001450
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  10. Article: Study on the molecular mechanism of anti-liver cancer effect of Evodiae fructus by network pharmacology and QSAR model.

    Chen, Peng-Yu / Han, Lin-Tao

    Frontiers in chemistry

    2023  Volume 10, Page(s) 1060500

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2022.1060500
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