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  1. Article: The medical and social aspect of lung diseases.

    D'ARCY HART, P M

    Proteccion social

    2010  Volume 9, Issue 99, Page(s) 42–52

    Title translation El aspecto médico y social de las enfermedades pulmonares.
    MeSH term(s) Lung Diseases
    Language Spanish
    Publishing date 2010-08-27
    Publishing country Bolivia
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Impact of Modifying Food Service Practices in Secondary Schools Providing a Routine Meal Service on Student's Food Behaviours, Health and Dining Experience: A Systematic Review and Meta-Analysis.

    Mingay, Edwina / Hart, Melissa / Yoong, Serene / Palazzi, Kerrin / D'Arcy, Ellie / Pursey, Kirrilly M / Hure, Alexis

    Nutrients

    2022  Volume 14, Issue 17

    Abstract: ... 1.12 to 1.23; p = 0.002), fruit serves selected (mean difference (MD): 0.09; 0.09 to 0.09; p < 0.001 ... and consumed (MD: 0.10; 0.04 to 0.15; p < 0.001), and vegetable serves consumed (MD: 0.06; 0.01 to 0 ... 10; p = 0.024). Vote-counting showed a positive impact for most interventions that measured selection ...

    Abstract The education sector is recognised as an ideal platform to promote good nutrition and decision making around food and eating. Examining adolescents in this setting is important because of the unique features of adolescence compared to younger childhood. This systematic review and meta-analysis examine interventions in secondary schools that provide a routine meal service and the impact on adolescents’ food behaviours, health and dining experience in this setting. The review was guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Checklist and Cochrane Handbook recommendations. Studies published in English searched in four databases and a hand search yielded 42 interventions in 35 studies. Risk of bias was assessed independently by two reviewers. Interventions were classified using the NOURISHING framework, and their impact analysed using meta-analysis, vote-counting synthesis or narrative summary. The meta-analysis showed an improvement in students selecting vegetables (odds ratio (OR): 1.39; 1.12 to 1.23; p = 0.002), fruit serves selected (mean difference (MD): 0.09; 0.09 to 0.09; p < 0.001) and consumed (MD: 0.10; 0.04 to 0.15; p < 0.001), and vegetable serves consumed (MD: 0.06; 0.01 to 0.10; p = 0.024). Vote-counting showed a positive impact for most interventions that measured selection (15 of 25; 41% to 77%; p = 0.002) and consumption (14 of 24; 39% to 76%; p = 0.013) of a meal component. Interventions that integrate improving menu quality, assess palatability, accessibility of healthier options, and student engagement can enhance success. These results should be interpreted with caution as most studies were not methodologically strong and at higher risk of bias. There is a need for higher quality pragmatic trials, strategies to build and measure sustained change, and evaluation of end-user attitudes and perceptions towards intervention components and implementation for greater insight into intervention success and future directions (PROSPERO registration: CRD42020167133).
    MeSH term(s) Adolescent ; Child ; Food Services ; Health Behavior ; Humans ; Schools ; Students ; Vegetables
    Language English
    Publishing date 2022-09-02
    Publishing country Switzerland
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14173640
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  3. Article: Historical declines in tuberculosis: nature, nurture and the biosocial model.

    D'Arcy Hart, P

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2001  Volume 5, Issue 9, Page(s) 879

    MeSH term(s) England/epidemiology ; Humans ; Income/statistics & numerical data ; Social Change ; Socioeconomic Factors ; Tuberculosis, Pulmonary/epidemiology ; Tuberculosis, Pulmonary/mortality ; Wales/epidemiology
    Language English
    Publishing date 2001-09
    Publishing country France
    Document type Comment ; Letter
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
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  4. Article: A change in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s.

    D'Arcy Hart, P

    BMJ (Clinical research ed.)

    1999  Volume 319, Issue 7209, Page(s) 572–573

    MeSH term(s) Antibiotics, Antitubercular/history ; Antibiotics, Antitubercular/therapeutic use ; Common Cold/drug therapy ; Common Cold/history ; Controlled Clinical Trials as Topic/history ; History, 20th Century ; Humans ; Patulin/history ; Patulin/therapeutic use ; Randomized Controlled Trials as Topic/history ; Streptomycin/history ; Streptomycin/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis/history
    Chemical Substances Antibiotics, Antitubercular ; Patulin (95X2BV4W8R) ; Streptomycin (Y45QSO73OB)
    Language English
    Publishing date 1999-08-28
    Publishing country England
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8138 ; 0959-8154 ; 0959-8146 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8138 ; 0959-8154 ; 0959-8146 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.319.7209.572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Enhancing effect of cortisone on tuberculosis in the mouse.

    D'ARCY HART, P / REES, R J W

    Lancet (London, England)

    2003  Volume 2, Issue 6630, Page(s) 391–395

    MeSH term(s) Animals ; Anti-Bacterial Agents ; Cortisone ; Mice ; Tuberculosis ; Tuberculosis, Pulmonary/therapy
    Chemical Substances Anti-Bacterial Agents ; Cortisone (V27W9254FZ)
    Language English
    Publishing date 2003-03-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0140-6736 ; 0023-7507
    ISSN (online) 1474-547X
    ISSN 0140-6736 ; 0023-7507
    DOI 10.1016/s0140-6736(50)91344-4
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  6. Article ; Online: Basal ganglia dysplasia and mTORopathy: A potential cause of postoperative seizures in focal cortical dysplasia.

    Lee, Wei Shern / Macdonald-Laurs, Emma / Stephenson, Sarah E M / D'Arcy, Colleen / MacGregor, Duncan / Leventer, Richard J / Maixner, Wirginia / Harvey, A Simon / Lockhart, Paul J

    Epilepsia open

    2022  Volume 8, Issue 1, Page(s) 205–210

    Abstract: ... a pathogenic somatic MTOR variant [NM_004958.4:c.4375G > C (p.Ala1459Pro)] that was not present in blood ...

    Abstract Pathogenic somatic MTOR variants in the cerebral cortex are a frequent cause of focal cortical dysplasia (FCD). We describe a child with drug and surgery-resistant focal epilepsy due to FCD type II who developed progressive enlargement and T2 signal hyperintensity in the ipsilateral caudate and lentiform nuclei. Histopathology of caudate nucleus biopsies showed dysmorphic neurons, similar to those in resected cortex. Genetic analysis of frontal and temporal cortex and caudate nucleus identified a pathogenic somatic MTOR variant [NM_004958.4:c.4375G > C (p.Ala1459Pro)] that was not present in blood-derived gDNA. The mean variant allele frequency ranged from 0.4% to 3.2% in cerebral cortex and up to 5.4% in the caudate nucleus. The basal ganglia abnormalities suggest more widespread, potentially hemispheric dysplasia in this patient, consistent with the pathogenic variant occurring in early cerebral development. This finding provides a potential explanation for persistent seizures in some patients with seemingly complete resection of FCD or disconnection of a dysplastic hemisphere.
    MeSH term(s) Child ; Humans ; Brain/metabolism ; Brain/pathology ; Brain/surgery ; Focal Cortical Dysplasia ; Seizures/pathology ; Basal Ganglia/metabolism ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
    Chemical Substances TOR Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2022-12-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2470-9239
    ISSN (online) 2470-9239
    DOI 10.1002/epi4.12678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The Impact of Modifying Food Service Practices in Secondary Schools Providing a Routine Meal Service on Student’s Food Behaviours, Health and Dining Experience: A Systematic Review and Meta-Analysis

    Mingay, Edwina / Hart, Melissa / Yoong, Serene / Palazzi, Kerrin / D’Arcy, Ellie / Pursey, Kirrilly M. / Hure, Alexis

    Nutrients. 2022 Sept. 02, v. 14, no. 17

    2022  

    Abstract: ... 1.12 to 1.23; p = 0.002), fruit serves selected (mean difference (MD): 0.09; 0.09 to 0.09; p < 0.001 ... and consumed (MD: 0.10; 0.04 to 0.15; p < 0.001), and vegetable serves consumed (MD: 0.06; 0.01 to 0 ... 10; p = 0.024). Vote-counting showed a positive impact for most interventions that measured selection ...

    Abstract The education sector is recognised as an ideal platform to promote good nutrition and decision making around food and eating. Examining adolescents in this setting is important because of the unique features of adolescence compared to younger childhood. This systematic review and meta-analysis examine interventions in secondary schools that provide a routine meal service and the impact on adolescents’ food behaviours, health and dining experience in this setting. The review was guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Checklist and Cochrane Handbook recommendations. Studies published in English searched in four databases and a hand search yielded 42 interventions in 35 studies. Risk of bias was assessed independently by two reviewers. Interventions were classified using the NOURISHING framework, and their impact analysed using meta-analysis, vote-counting synthesis or narrative summary. The meta-analysis showed an improvement in students selecting vegetables (odds ratio (OR): 1.39; 1.12 to 1.23; p = 0.002), fruit serves selected (mean difference (MD): 0.09; 0.09 to 0.09; p < 0.001) and consumed (MD: 0.10; 0.04 to 0.15; p < 0.001), and vegetable serves consumed (MD: 0.06; 0.01 to 0.10; p = 0.024). Vote-counting showed a positive impact for most interventions that measured selection (15 of 25; 41% to 77%; p = 0.002) and consumption (14 of 24; 39% to 76%; p = 0.013) of a meal component. Interventions that integrate improving menu quality, assess palatability, accessibility of healthier options, and student engagement can enhance success. These results should be interpreted with caution as most studies were not methodologically strong and at higher risk of bias. There is a need for higher quality pragmatic trials, strategies to build and measure sustained change, and evaluation of end-user attitudes and perceptions towards intervention components and implementation for greater insight into intervention success and future directions (PROSPERO registration: CRD42020167133).
    Keywords adolescence ; childhood ; education ; food service ; fruits ; meta-analysis ; nutrition ; odds ratio ; palatability ; risk ; systematic review ; vegetables
    Language English
    Dates of publication 2022-0902
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14173640
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Re-emergence of tuberculosis.

    D'arcy Hart, P

    BMJ (Clinical research ed.)

    1993  Volume 306, Issue 6876, Page(s) 515

    MeSH term(s) BCG Vaccine ; HIV Infections/complications ; Humans ; Tuberculosis/prevention & control
    Chemical Substances BCG Vaccine
    Language English
    Publishing date 1993-02-20
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8138 ; 0959-8154 ; 0959-8146 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8138 ; 0959-8154 ; 0959-8146 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.306.6876.515
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  9. Article: Derivative of p-aminosalicylic acid with enhanced antituberculous activity.

    HARINGTON, C R / D'ARCY HART, P / REES, R J W

    Lancet (London, England)

    2003  Volume 1, Issue 6767, Page(s) 929–930

    MeSH term(s) Aminosalicylic Acids ; Thiosemicarbazones ; Tuberculosis
    Chemical Substances Aminosalicylic Acids ; Thiosemicarbazones
    Language English
    Publishing date 2003-03-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0140-6736 ; 0023-7507
    ISSN (online) 1474-547X
    ISSN 0140-6736 ; 0023-7507
    DOI 10.1016/s0140-6736(53)92066-2
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  10. Article: PRiME: integrating professional responsibility into the engineering curriculum.

    Moore, Christy / Hart, Hillary / Randall, D'Arcy / Nichols, Steven P

    Science and engineering ethics

    2006  Volume 12, Issue 2, Page(s) 273–289

    Abstract: Engineering educators have long discussed the need to teach professional responsibility and the social context of engineering without adding to overcrowded curricula. One difficulty we face is the lack of appropriate teaching materials that can fit into ... ...

    Abstract Engineering educators have long discussed the need to teach professional responsibility and the social context of engineering without adding to overcrowded curricula. One difficulty we face is the lack of appropriate teaching materials that can fit into existing courses. The PRiME (Professional Responsibility Modules for Engineering) Project (http://www.engr.utexas.edu/ethics/primeModules.cfm) described in this paper was initiated at the University of Texas, Austin to provide web-based modules that could be integrated into any undergraduate engineering class. Using HPL (How People Learn) theory, PRiME developed and piloted four modules during the academic year 2004-2005. This article introduces the modules and the pilot, outlines the assessment process, analyzes the results, and describes how the modules are being revised in light of the initial assessment. In its first year of development and testing, PRiME made significant progress towards meeting its objectives. The PRiME Project can strengthen engineering education by providing faculty with an effective system for engaging students in learning about professional responsibility.
    MeSH term(s) Computer-Assisted Instruction ; Curriculum ; Engineering/education ; Engineering/ethics ; Ethics, Professional/education ; Humans ; Internet ; Social Responsibility ; Teaching/methods ; United States
    Language English
    Publishing date 2006-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2136491-6
    ISSN 1471-5546 ; 1353-3452
    ISSN (online) 1471-5546
    ISSN 1353-3452
    DOI 10.1007/s11948-006-0027-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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