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  1. Article: Microbiologic Diagnosis of Pyogenic Spondylitis.

    Kim, Nam Joong

    Infection & chemotherapy

    2021  Volume 53, Issue 2, Page(s) 238–246

    Abstract: Pyogenic spondylitis requires long-term antibiotics treatment and identification of the etiologic microorganism is essential. The first test in the microbiologic diagnosis of pyogenic spondylitis is a blood culture. Any microorganisms that grow in blood ... ...

    Abstract Pyogenic spondylitis requires long-term antibiotics treatment and identification of the etiologic microorganism is essential. The first test in the microbiologic diagnosis of pyogenic spondylitis is a blood culture. Any microorganisms that grow in blood culture are highly likely to be the etiological microorganisms of pyogenic spondylitis. If the microbial etiology cannot be defined by the blood culture, a needle biopsy is performed on the inflamed tissues. Here, it is recommended that paraspinal tissues, rather than spinal tissues, are collected to increase the positive rate in tissue culture. If the microbial etiology cannot be defined by the first needle biopsy, another needle biopsy may be performed. The collected tissue sample is used in culture tests on bacteria and mycobacteria as well as pathological tests. If tuberculous spondylitis is suspected, polymerase chain reaction is carried out to detect
    Language English
    Publishing date 2021-07-02
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2021.0054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6842: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Dualistic Effects of PRKAR1A as a Potential Anticancer Target in Cancer Cells and Cancer-Derived Stem Cells.

    Baek, Joong-Won / Nam, A-Reum / Kim, Kyunggon / Kim, Pyung-Hwan

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: The integration of innovative medical technologies and interdisciplinary collaboration could improve the treatment of cancer, a globally prevalent and often deadly disease. Despite recent advancements, current cancer therapies fail to specifically ... ...

    Abstract The integration of innovative medical technologies and interdisciplinary collaboration could improve the treatment of cancer, a globally prevalent and often deadly disease. Despite recent advancements, current cancer therapies fail to specifically address recurrence and target cancer stem cells (CSCs), which contribute to relapse. In this study, we utilized three types of cancer cells, from which three types of CSCs were further derived, to conduct a proteomic analysis. Additionally, shared cell surface biomarkers were identified as potential targets for a comprehensive treatment strategy. The selected biomarkers were evaluated through short hairpin RNA treatment, which revealed contrasting functions in cancer cells and CSCs. Knockdown of the identified proteins revealed that they regulate the epithelial-mesenchymal transition (EMT) and stemness via the ERK signaling pathway. Resistance to anticancer agents was consequently reduced, ultimately enhancing the overall anticancer effects of the treatment. Additionally, the significance of these biomarkers in clinical patient outcomes was confirmed using bioinformatics. Our study suggests a novel cancer treatment strategy that addresses the limitations of current anticancer therapies.
    MeSH term(s) Humans ; Cell Line, Tumor ; Proteomics ; Antineoplastic Agents/pharmacology ; Biomarkers/metabolism ; Transcription Factors/metabolism ; Neoplastic Stem Cells/metabolism ; Epithelial-Mesenchymal Transition ; Neoplasms/metabolism ; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit/metabolism
    Chemical Substances Antineoplastic Agents ; Biomarkers ; Transcription Factors ; PRKAR1A protein, human ; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
    Language English
    Publishing date 2024-03-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Triphasic Ni

    Malhotra, Deepanshu / Nguyen, Thanh Hai / Tran, Duy Thanh / Dinh, Van An / Kim, Nam Hoon / Lee, Joong Hee

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2309122

    Abstract: This research designs a triphasic ... ...

    Abstract This research designs a triphasic Ni
    Language English
    Publishing date 2024-02-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202309122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Enhanced deep learning model enables accurate alignment measurement across diverse institutional imaging protocols.

    Kim, Sung Eun / Nam, Jun Woo / Kim, Joong Il / Kim, Jong-Keun / Ro, Du Hyun

    Knee surgery & related research

    2024  Volume 36, Issue 1, Page(s) 4

    Abstract: Background: Achieving consistent accuracy in radiographic measurements across different equipment and protocols is challenging. This study evaluates an advanced deep learning (DL) model, building upon a precursor, for its proficiency in generating ... ...

    Abstract Background: Achieving consistent accuracy in radiographic measurements across different equipment and protocols is challenging. This study evaluates an advanced deep learning (DL) model, building upon a precursor, for its proficiency in generating uniform and precise alignment measurements in full-leg radiographs irrespective of institutional imaging differences.
    Methods: The enhanced DL model was trained on over 10,000 radiographs. Utilizing a segmented approach, it separately identified and evaluated regions of interest (ROIs) for the hip, knee, and ankle, subsequently integrating these regions. For external validation, 300 datasets from three distinct institutes with varied imaging protocols and equipment were employed. The study measured seven radiologic parameters: hip-knee-ankle angle, lateral distal femoral angle, medial proximal tibial angle, joint line convergence angle, weight-bearing line ratio, joint line obliquity angle, and lateral distal tibial angle. Measurements by the model were compared with an orthopedic specialist's evaluations using inter-observer and intra-observer intraclass correlation coefficients (ICCs). Additionally, the absolute error percentage in alignment measurements was assessed, and the processing duration for radiograph evaluation was recorded.
    Results: The DL model exhibited excellent performance, achieving an inter-observer ICC between 0.936 and 0.997, on par with an orthopedic specialist, and an intra-observer ICC of 1.000. The model's consistency was robust across different institutional imaging protocols. Its accuracy was particularly notable in measuring the hip-knee-ankle angle, with no instances of absolute error exceeding 1.5 degrees. The enhanced model significantly improved processing speed, reducing the time by 30-fold from an initial 10-11 s to 300 ms.
    Conclusions: The enhanced DL model demonstrated its ability for accurate, rapid alignment measurements in full-leg radiographs, regardless of protocol variations, signifying its potential for broad clinical and research applicability.
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2673841-7
    ISSN 2234-2451 ; 2234-0726
    ISSN (online) 2234-2451
    ISSN 2234-0726
    DOI 10.1186/s43019-023-00209-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Single-step fabrication of surface morphology tuned iron oxide anchored highly porous carbon nanotube hybrid foam for a highly stable supercapacitor electrode.

    Park, Ok-Kyung / Kim, Nam Hoon / Lee, Joong Hee

    Journal of colloid and interface science

    2023  Volume 641, Page(s) 479–491

    Abstract: The pseudocapacitive metal oxide anchored nanocarbon-based three-dimensional (3D) materials are considered attractive electrode materials for high-performance supercapacitor applications. However, the complex multistep synthesis approaches raise ... ...

    Abstract The pseudocapacitive metal oxide anchored nanocarbon-based three-dimensional (3D) materials are considered attractive electrode materials for high-performance supercapacitor applications. However, the complex multistep synthesis approaches raise production costs and act as a major barrier to the practical real-world field. To overcome this limitation, in this study, an easily scalable and effective fabrication approach for the development of iron oxide (Fe
    Language English
    Publishing date 2023-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2023.03.087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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  6. Article: An Integrative Study of

    Seo, Yun-Soo / Song, Jun-Ho / Kim, Hyo Seon / Nam, Hyeon Hwa / Yang, Sungyu / Choi, Goya / Chae, Sung-Wook / Lee, Jeongmin / Jung, Bokyung / Kim, Joong-Sun / Park, Inkyu

    Pharmaceutics

    2024  Volume 16, Issue 4

    Abstract: ... ...

    Abstract Scrophularia
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics16040529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Trend in CD4+ Cell Counts at Diagnosis in Human Immunodeficiency Virus-Infected Persons in Korea.

    Kim, Nam Joong

    Infection & chemotherapy

    2017  Volume 49, Issue 2, Page(s) 155–157

    Language English
    Publishing date 2017-07-05
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2017.49.2.155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6842: Show issues Location:
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  8. Article ; Online: Is fear of disease progression associated with antiretroviral therapy adherence in persons with HIV/AIDS?

    Yeom, Chan-Woo / Ha, Hyeju / Hahm, Bong-Jin / Hee Lee, Sun / Joong Kim, Nam / Shim, Eun-Jung

    Journal of health psychology

    2024  , Page(s) 13591053231224177

    Abstract: We examined the mediating role of depression and anxiety on the relationship between fear of disease progression (FoP) and antiretroviral therapy (ART) adherence and the moderating role of social support in the FoP-depression/anxiety-ART adherence ... ...

    Abstract We examined the mediating role of depression and anxiety on the relationship between fear of disease progression (FoP) and antiretroviral therapy (ART) adherence and the moderating role of social support in the FoP-depression/anxiety-ART adherence relationship in persons with HIV/AIDS (PWHA). 202 PWHA completed self-report measures. Simple mediation and moderated mediation analyses were performed. FoP was directly and negatively associated with ART adherence, and the mediating role of depression in this relationship was significant. Indirect effect of FoP mediated by anxiety on ART adherence was not significant. The moderating effect of social support was significant in the FoP-depression pathway, while the indirect effect of FoP on ART adherence mediated by depression was greatest at a higher level of social support and lower level of FoP. The results suggest the relevance of high FoP and depression-mediated FoP in ART adherence and social support may attenuate the negative impact of FoP.
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2021897-7
    ISSN 1461-7277 ; 1359-1053
    ISSN (online) 1461-7277
    ISSN 1359-1053
    DOI 10.1177/13591053231224177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ethanol purification enables high-quality α-phase FAPbI

    Kim, Hyun Seo / Yun, Hyun-Sung / Seo, Chae-Eun / Bin Yoo, Soo / Kang, Bong Joo / Jung, Eui Hyuk / Jeon, Nam Joong

    Nanoscale horizons

    2024  

    Abstract: Reliable quality and sustainable processes must be developed for commodities to enter the commercial stage. For next-generation photovoltaic applications such as perovskite solar cells, it is essential to manufacture high-quality photoactive ... ...

    Abstract Reliable quality and sustainable processes must be developed for commodities to enter the commercial stage. For next-generation photovoltaic applications such as perovskite solar cells, it is essential to manufacture high-quality photoactive perovskites
    Language English
    Publishing date 2024-05-02
    Publishing country England
    Document type Journal Article
    ISSN 2055-6764
    ISSN (online) 2055-6764
    DOI 10.1039/d4nh00061g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Anti-Atopic Effect of

    Lee, Jeongmin / Seo, Yun-Soo / Lee, A Yeong / Nam, Hyeon-Hwa / Ji, Kon-Young / Kim, Taesoo / Lee, Sanghyun / Hyun, Jin Won / Moon, Changjong / Cho, Yongho / Jung, Bokyung / Kim, Joong Sun / Chae, Sungwook

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 3

    Abstract: Scutellaria ... ...

    Abstract Scutellaria baicalensis
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17030269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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