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  1. Article ; Online: Two-dimensional TiCl

    Zhu, Hong-Yao / Ye, Xiao-Juan / Meng, Lan / Zheng, Xiao-Hong / Jia, Ran / Liu, Chun-Sheng

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 16, Page(s) 11513–11521

    Abstract: Na-ion batteries (NIBs) have attracted a great deal of attention for large-scale electric energy storage due to their inherent safety, natural abundant resources, and low cost. The exploration of suitable anode materials is the major challenge in ... ...

    Abstract Na-ion batteries (NIBs) have attracted a great deal of attention for large-scale electric energy storage due to their inherent safety, natural abundant resources, and low cost. The exploration of suitable anode materials is the major challenge in advancing NIB technology. On the basis of first-principles calculations, we systematically explore the potential performance of two-dimensional (2D) TiCl
    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp00172e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Which model is more efficient in carbon emission prediction research? A comparative study of deep learning models, machine learning models, and econometric models.

    Yao, Xiao / Zhang, Hong / Wang, Xiyue / Jiang, Yadong / Zhang, Yuxi / Na, Xiaohong

    Environmental science and pollution research international

    2024  Volume 31, Issue 13, Page(s) 19500–19515

    Abstract: Accurately predicting future carbon emissions is of great significance for the government to scientifically promote carbon emission reduction policies. Among the current technologies for forecasting carbon emissions, the most prominent ones are ... ...

    Abstract Accurately predicting future carbon emissions is of great significance for the government to scientifically promote carbon emission reduction policies. Among the current technologies for forecasting carbon emissions, the most prominent ones are econometric models and deep learning, but few works have systematically compared and analyzed the forecasting performance of the methods. Therefore, the paper makes a comparison for deep learning model, machine learning model, and the econometric model to demonstrate whether deep learning is an efficient method for carbon emission prediction research. In model mechanism, neural network for deep learning refers to an information processing model established by simulating biological neural system, and the model can be further extended through bionic characteristics. So the paper further optimizes the model from the perspective of bionics and proposes an innovative deep learning model based on the memory behavior mechanism of group creatures. Comparison results show that the prediction accuracy of the heuristic neural network is higher than that of the econometric model. Through in-depth analysis, the heuristic neural network is more suitable for predicting future carbon emissions, while the econometric model is more suitable for clarifying the impact of influencing factors on carbon emissions.
    MeSH term(s) Deep Learning ; Models, Econometric ; Carbon ; Machine Learning ; Neural Networks, Computer ; Forecasting ; China
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2024-02-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32083-w
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    Z 5915: Show issues

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  3. Article ; Online: Bioinspired Binickel Catalyst for Carbon Dioxide Reduction: The Importance of Metal-ligand Cooperation.

    Xiao, Yao / Xie, Fei / Zhang, Hong-Tao / Zhang, Ming-Tian

    JACS Au

    2024  Volume 4, Issue 3, Page(s) 1207–1218

    Abstract: Catalyst design for the efficient ... ...

    Abstract Catalyst design for the efficient CO
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3704
    ISSN (online) 2691-3704
    DOI 10.1021/jacsau.4c00047
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  4. Article: Notes on species of

    Li, Cong-Zheng / Yao, Yan-Bin / Xiao, Yong-Hong / Xu, Xiang / Liu, Ke-Ke

    ZooKeys

    2024  Volume 1190, Page(s) 195–212

    Abstract: Taxonomic notes on ... ...

    Abstract Taxonomic notes on the
    Language English
    Publishing date 2024-01-29
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2445640-8
    ISSN 1313-2970 ; 1313-2989
    ISSN (online) 1313-2970
    ISSN 1313-2989
    DOI 10.3897/zookeys.1190.111583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis.

    Hou, Li-Shuang / Zhai, Xiao-Pei / Zhang, Yao-Wen / Xing, Jie-Hua / Li, Chen / Zhou, Si-Yuan / Zhu, Xiao-Hong / Zhang, Bang-Le

    Liver international : official journal of the International Association for the Study of the Liver

    2024  

    Abstract: Background and purpose: Liver fibrosis is a wound-healing reaction which is the main cause of chronic liver diseases worldwide. The activated hepatic stellate cell (aHSC) is the main driving factor in the development of liver fibrosis. Inhibiting ... ...

    Abstract Background and purpose: Liver fibrosis is a wound-healing reaction which is the main cause of chronic liver diseases worldwide. The activated hepatic stellate cell (aHSC) is the main driving factor in the development of liver fibrosis. Inhibiting autophagy of aHSC can prevent the progression of liver fibrosis, but inhibiting autophagy of other liver cells has opposite effects. Hence, targeted inhibition of autophagy in aHSC is quite necessary for the treatment of liver fibrosis, which prompts us to explore the targeted delivery system of small molecule autophagy inhibitor hydroxychloroquine (HCQ) that can target aHSC and alleviate the liver fibrosis.
    Methods: The delivery system of HCQ@retinol-liposome nanoparticles (HCQ@ROL-LNPs) targeting aHSC was constructed by the film dispersion and pH-gradient method. TGF-β-induced HSC activation and thioacetamide (TAA)-induced liver fibrosis mice model were established, and the targeting ability and therapeutic effect of HCQ@ROL-LNPs in liver fibrosis were studied subsequently in vitro and in vivo.
    Results: HCQ@ROL-LNPs have good homogeneity and stability. They inhibited the autophagy of aHSC selectively by HCQ and reduced the deposition of extracellular matrix (ECM) and the damage to other liver cells. Compared with the free HCQ and HCQ@LNPs, HCQ@ROL-LNPs had good targeting ability, showing enhanced therapeutic effect and low toxicity to other organs.
    Conclusion: Construction of HCQ@ROL-LNPs delivery system lays a theoretical and experimental foundation for the treatment of liver fibrosis and promotes the development of clinical therapeutic drugs for liver diseases.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.15915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Endogenous Nb

    Xiao, Junpeng / Yu, Peng / Gao, Hong / Yao, Jing

    Journal of colloid and interface science

    2023  Volume 652, Issue Pt A, Page(s) 113–121

    Abstract: Schottky heterostructures have significant advantages for exciting charge transfer kinetics at material interfaces. In this work, endogenous ... ...

    Abstract Schottky heterostructures have significant advantages for exciting charge transfer kinetics at material interfaces. In this work, endogenous Nb
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2023.08.036
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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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  7. Article ; Online: Codelivery of anti-CD47 antibody and chlorin e6 using a dual pH-sensitive nanodrug for photodynamic immunotherapy of osteosarcoma.

    Xiao, Jijie / Xiao, Hong / Cai, Yujun / Liao, Jianwei / Liu, Jue / Yao, Lin / Li, Shaolin

    Oncology research

    2024  Volume 32, Issue 4, Page(s) 691–702

    Abstract: Osteosarcoma is a malignant tumor originating from bone tissue that progresses rapidly and has a poor patient prognosis. Immunotherapy has shown great potential in the treatment of osteosarcoma. However, the immunosuppressive microenvironment severely ... ...

    Abstract Osteosarcoma is a malignant tumor originating from bone tissue that progresses rapidly and has a poor patient prognosis. Immunotherapy has shown great potential in the treatment of osteosarcoma. However, the immunosuppressive microenvironment severely limits the efficacy of osteosarcoma treatment. The dual pH-sensitive nanocarrier has emerged as an effective antitumor drug delivery system that can selectively release drugs into the acidic tumor microenvironment. Here, we prepared a dual pH-sensitive nanocarrier, loaded with the photosensitizer Chlorin e6 (Ce6) and CD47 monoclonal antibodies (aCD47), to deliver synergistic photodynamic and immunotherapy of osteosarcoma. On laser irradiation, Ce6 can generate reactive oxygen species (ROS) to kill cancer cells directly and induces immunogenic tumor cell death (ICD), which further facilitates the dendritic cell maturation induced by blockade of CD47 by aCD47. Moreover, both calreticulin released during ICD and CD47 blockade can accelerate phagocytosis of tumor cells by macrophages, promote antigen presentation, and eventually induce T lymphocyte-mediated antitumor immunity. Overall, the dual pH-sensitive nanodrug loaded with Ce6 and aCD47 showed excellent immune-activating and anti-tumor effects in osteosarcoma, which may lay the theoretical foundation for a novel combination model of osteosarcoma treatment.
    MeSH term(s) Humans ; Photochemotherapy ; CD47 Antigen ; Cell Line, Tumor ; Osteosarcoma/drug therapy ; Neoplasms ; Immunotherapy ; Bone Neoplasms/drug therapy ; Nanoparticles ; Hydrogen-Ion Concentration ; Tumor Microenvironment ; Chlorophyllides
    Chemical Substances phytochlorin (5S2CCF3T1Z) ; CD47 Antigen ; CD47 protein, human ; Chlorophyllides
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1114699-0
    ISSN 1555-3906 ; 0965-0407
    ISSN (online) 1555-3906
    ISSN 0965-0407
    DOI 10.32604/or.2023.030767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3087: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Disorganized adrenocortical zonational structure in COVID-19 patients: Implications of critical illness duration.

    Wen, Tian-Zi / Fu, Wen-Juan / Xiao, Shi-Qi / Wang, Shuai / Li, Tian-Ran / Chen, Xin-Yu / Chen, He-Yuan / Luo, Jie / Bian, Xiu-Wu / Yao, Xiao-Hong

    Pathology, research and practice

    2024  Volume 256, Page(s) 155251

    Abstract: Aberrant adrenal function has been frequently reported in COVID-19 patients, but histopathological evidence remains limited. This retrospective autopsy study aims to scrutinize the impact of COVID-19 duration on adrenocortical zonational architecture and ...

    Abstract Aberrant adrenal function has been frequently reported in COVID-19 patients, but histopathological evidence remains limited. This retrospective autopsy study aims to scrutinize the impact of COVID-19 duration on adrenocortical zonational architecture and peripheral corticosteroid reactivity. The adrenal glands procured from 15 long intensive care unit (ICU)-stay COVID-19 patients, 9 short ICU-stay COVID-19 patients, and 20 matched controls. Subjects who had received glucocorticoid treatment prior to sampling were excluded. Applying hematoxylin and eosin (H&E) and immunohistochemical (IHC) staining, we disclosed that the adrenocortical zonational structure was substantially disorganized in COVID-19 patients, which long ICU-stay patients manifested a higher prevalence of severe disorganization (67%) than short ICU-stay patients (11%; P = 0.0058). The adrenal cortex of COVID-19 patients exhibited a 40% decrease in the zona glomerulosa (ZG) area and a 74% increase in the zona fasciculata (ZF) area (both P < 0.0001) relative to controls. Furthermore, among long ICU-stay COVID-19 patients, the ZG area diminished by 31% (P = 0.0004), and the ZF area expanded by 27% (P = 0.0004) in comparison to short ICU-stay patients. The zona reticularis (ZR) area remained unaltered. Nuclear translocation of corticosteroid receptors in the liver and kidney of long ICU-stay COVID-19 patients was at least 43% lower than in short ICU-stay patients (both P < 0.05). These findings underscore the necessity for clinicians to monitor adrenal function in long-stay COVID-19 patients.
    MeSH term(s) Humans ; Critical Illness ; Retrospective Studies ; COVID-19 ; Adrenal Cortex ; Adrenal Glands ; Adrenal Cortex Hormones
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2024-03-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2024.155251
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    Ud III Zs.20: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Exposure to acute waterborne cadmium caused severe damage on lipid metabolism of freshwater fish, revealed by nuclear lipid droplet deposition in hepatocytes of rare minnow.

    Liu, Xiao-Hong / Pang, Xu / Jin, Li / Pu, De-Yong / Wang, Zhi-Jian / Zhang, Yao-Guang

    Aquatic toxicology (Amsterdam, Netherlands)

    2023  Volume 257, Page(s) 106433

    Abstract: Cadmium (Cd) is a widely distributed aquatic toxic heavy metal with the potential to disrupt fish metabolism; however, more research is needed to clarify the underlying mechanisms. In the present study, rare minnows (Gobiocypris rarus) were used to ... ...

    Abstract Cadmium (Cd) is a widely distributed aquatic toxic heavy metal with the potential to disrupt fish metabolism; however, more research is needed to clarify the underlying mechanisms. In the present study, rare minnows (Gobiocypris rarus) were used to detect the effects of cadmium on freshwater fish lipid metabolism and its underlying mechanism by histopathological observation, measurement of serum and liver biochemical indexes, and analysis of gene expression in terms of lipid oxidation, synthesis and transport. Here, severe damage, such as cytoplasmic lipid droplet (LD) accumulation, ectopic deposition of LDs, and the appearance of nuclear LDs (nLDs), was detected after exposure to 2.0 mg/L or higher concentrations (2.5 and 2.8 mg/L CdCl
    MeSH term(s) Animals ; Cadmium/toxicity ; Cadmium/metabolism ; Lipid Metabolism ; Lipid Droplets ; Water Pollutants, Chemical/toxicity ; Hepatocytes/metabolism ; Cyprinidae/metabolism ; Liver ; Triglycerides/metabolism ; Lipase/metabolism ; Lipase/pharmacology ; RNA, Messenger/metabolism ; Cholesterol/metabolism
    Chemical Substances Cadmium (00BH33GNGH) ; Water Pollutants, Chemical ; Triglycerides ; Lipase (EC 3.1.1.3) ; RNA, Messenger ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2023-02-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782699-0
    ISSN 1879-1514 ; 0166-445X
    ISSN (online) 1879-1514
    ISSN 0166-445X
    DOI 10.1016/j.aquatox.2023.106433
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    Zs.A 4376: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article: [Characteristics of Bacterial Community Structure in Wuliangsu Lake During an Irrigation Interval in Hetao Plain].

    Shi, Yu-Jiao / Li, Wen-Bao / Zhang, Bo-Yao / Yao, Guo-Wang / Shi, Xiao-Hong

    Huan jing ke xue= Huanjing kexue

    2022  Volume 43, Issue 3, Page(s) 1424–1433

    Abstract: In order to study the bacterial community composition and corresponding function in Wuliangsu Lake at the end of the Hetao Plain during the irrigation gap period, lake samples were collected in September 2020, and the pH, TN, TP, DIP, DTP, ... ...

    Abstract In order to study the bacterial community composition and corresponding function in Wuliangsu Lake at the end of the Hetao Plain during the irrigation gap period, lake samples were collected in September 2020, and the pH, TN, TP, DIP, DTP, NH
    MeSH term(s) Actinobacteria ; China ; Cyanobacteria ; Lakes/microbiology ; Plankton ; RNA, Ribosomal, 16S/genetics
    Chemical Substances RNA, Ribosomal, 16S
    Language Chinese
    Publishing date 2022-03-07
    Publishing country China
    Document type Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
    DOI 10.13227/j.hjkx.202107108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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