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  1. Article ; Online: Integrating antimicrobial photodynamic therapy into the adjuvant phototherapeutic approach for orofacial manifestations of toxic epidermal necrolysis and Stevens-Johnson syndrome.

    Raffaele, Regina Maria / Ramires, Marcia Christina Camargo Hernandes / Baldo, Mario Eduardo / Palma, Luiz Felipe / Campos, Luana

    Photodiagnosis and photodynamic therapy

    2024  Volume 46, Page(s) 104011

    Abstract: Characterized by an immune reaction to medications, toxic epidermal necrolysis (TEN) and Steven-Johnson Syndrome (SJS) are potentially fatal mucocutaneous reactions, and their management remains challenging. Considering the promising studies regarding ... ...

    Abstract Characterized by an immune reaction to medications, toxic epidermal necrolysis (TEN) and Steven-Johnson Syndrome (SJS) are potentially fatal mucocutaneous reactions, and their management remains challenging. Considering the promising studies regarding the use of laser in managing orofacial lesions, this study aimed to report two cases in which children presenting with TEN and SJS were treated using a combination of antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) concurrently with conventional supportive care. The treatment proposed herein resulted in significant clinical improvement of the children's oral condition within a few days, enabling the reintroduction of oral feeding. Within the limitations of the study, the cases reported suggest that the adjuvant combination of PBMT and aPDT may be beneficial for improving the oral condition of children afflicted with oral injuries induced by TEN and SJS.
    Language English
    Publishing date 2024-02-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2024.104011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Critically Ill Patients With COVID-19: Are Phototherapies Advantageous for Managing Orofacial Lesions? Our Experience With Brazilian Hospitals.

    Campos, Luana / Teixeira, Inessa Solek / Ramires, Marcia Christina Camargo Hernandes / Raffaele, Regina Maria / Palma, Luiz Felipe

    Journal of lasers in medical sciences

    2023  Volume 14, Page(s) e5

    Language English
    Publishing date 2023-02-25
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2658681-2
    ISSN 2228-6721 ; 2008-9783
    ISSN (online) 2228-6721
    ISSN 2008-9783
    DOI 10.34172/jlms.2023.05
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Photodynamic viral inactivation in COVID-19-related orofacial lesions: myth or fact?

    Campos, Luana / Ramires, Marcia Christina Camargo Hernandes / Oliveira, Maria Teresa Santos / Zerbinati, Rodrigo / Braz-Silva, Paulo / Martins, Fabiana / Palma, Luiz Felipe

    Photodiagnosis and photodynamic therapy

    2023  Volume 42, Page(s) 103553

    MeSH term(s) Humans ; COVID-19 ; Virus Inactivation ; Photochemotherapy/methods ; Photosensitizing Agents/therapeutic use ; SARS-CoV-2
    Chemical Substances Photosensitizing Agents
    Language English
    Publishing date 2023-04-04
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2023.103553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A combination of phototherapy modalities for extensive lip lesions in a patient with SARS-CoV-2 infection.

    Ramires, Marcia Christina Camargo Hernandes / Mattia, Muriele Barbara / Tateno, Ricardo Yudi / Palma, Luiz Felipe / Campos, Luana

    Photodiagnosis and photodynamic therapy

    2021  Volume 33, Page(s) 102196

    Abstract: Many oral signs and symptoms related to the novel coronavirus disease (COVID-19) have been reported; however, both prevalence and etiology are still undetermined. Since the clinical features of the oral lesions seen in COVID-19 are highly heterogeneous ... ...

    Abstract Many oral signs and symptoms related to the novel coronavirus disease (COVID-19) have been reported; however, both prevalence and etiology are still undetermined. Since the clinical features of the oral lesions seen in COVID-19 are highly heterogeneous and the treatments differ considerably in the literature, the present study aimed to report a clinical case in which a combination of antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) was used for extensive lip lesions in a patient suffering from COVID-19. Within 4 days and without any systemic drug administration, after two sessions of aPDT and one session of PBMT, the lip lesions were completely healed, and the patient recovered her orofacial functions satisfactorily. According to the current case report and taking into consideration the evident lack of information about many aspects of COVID-19 infection, this combination of phototherapy modalities seems to be a promising tool for managing COVID-19-related lip lesions; however, more studies are necessary.
    MeSH term(s) COVID-19/pathology ; Female ; Humans ; Lip/drug effects ; Lip/pathology ; Low-Level Light Therapy/methods ; Methylene Blue/therapeutic use ; Middle Aged ; Photochemotherapy/methods ; Photosensitizing Agents/therapeutic use ; SARS-CoV-2
    Chemical Substances Photosensitizing Agents ; Methylene Blue (T42P99266K)
    Language English
    Publishing date 2021-01-28
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2021.102196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Intranasal photobiomodulation therapy for COVID-19-related olfactory dysfunction: A Brazilian multicenter case series.

    Soares, Luís Eduardo Silva / Guirado, Milena Miranda Goulart / Berlingieri, Giuseppina / Ramires, Marcia Christina Camargo Hernandes / Lyra, Luciana Aparecida de Oliveira P / Teixeira, Inessa Solek / Oliveira, Patrícia Costa / Tateno, Ricardo Yudi / Palma, Luiz Felipe / Campos, Luana

    Photodiagnosis and photodynamic therapy

    2021  Volume 36, Page(s) 102574

    Abstract: Olfactory dysfunction is commonly seen in COVID-19 patients; however, little is known about the pathophysiology and management. The present study aimed to report a series of cases in which three protocols of intranasal photobiomodulation therapy (PBMT) ... ...

    Abstract Olfactory dysfunction is commonly seen in COVID-19 patients; however, little is known about the pathophysiology and management. The present study aimed to report a series of cases in which three protocols of intranasal photobiomodulation therapy (PBMT) were used for COVID-19-related olfactory dysfunction. Irrespective of the PBMT protocol, olfaction recovery was noted in all cases but with varying degrees of improvement. Although intranasal PBMT seems to be a promising therapeutic modality, more research is needed to better define effectiveness.
    MeSH term(s) COVID-19 ; Humans ; Low-Level Light Therapy ; Olfaction Disorders/drug therapy ; Olfaction Disorders/therapy ; Photochemotherapy/methods ; Photosensitizing Agents/therapeutic use ; SARS-CoV-2 ; Smell
    Chemical Substances Photosensitizing Agents
    Language English
    Publishing date 2021-10-07
    Publishing country Netherlands
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2021.102574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Brazilian multicenter pilot case series on the efficacy of photobiomodulation therapy for COVID-19-related taste dysfunction.

    Campos, Luana / Soares, Luís Eduardo Silva / Berlingieri, Giuseppina / Ramires, Marcia Christina Camargo Hernandes / Guirado, Milena Miranda Goulart / Lyra, Luciana Aparecida de Oliveira P / Teixeira, Inessa Solek / Oliveira, Patrícia Costa / Alvares, Cristina Maria Arvate / Palma, Luiz Felipe

    Photodiagnosis and photodynamic therapy

    2021  Volume 37, Page(s) 102643

    Abstract: Background and aim: Among the most common symptoms of COVID-19 is taste dysfunction, which has a ranging clinical presentation. As well as its pathophysiology remains to be unclear, there is not enough information about the efficacy and safety of the ... ...

    Abstract Background and aim: Among the most common symptoms of COVID-19 is taste dysfunction, which has a ranging clinical presentation. As well as its pathophysiology remains to be unclear, there is not enough information about the efficacy and safety of the available treatments. This study aims to report a series of cases using PBMT for the management of COVID-19-related taste impairment.
    Case series: 8 female and 2 male patients sought medical help for taste impairment (either partially or completely) after COVID-19 infection. Photobiomodulation therapy (PBMT) on the tongue mucosa was then proposed but with 3 different protocols. Taste perception at baseline and before every laser session was evaluated using a visual analog scale. Irrespective of the PBMT protocol, taste recovery was noted in all cases but with varying degrees of improvement.
    Conclusion: given the high prevalence rates of taste dysfunction in COVID-19 patients and the lack of information about the available treatments, PBMT seems to be a promising therapeutic modality but not dependent on the total number of laser sessions and the interval between them. The choice of the most suitable laser protocol as well as the knowledge of the exact photonic mechanisms, however, need to be better studied.
    MeSH term(s) COVID-19 ; Female ; Humans ; Low-Level Light Therapy/methods ; Male ; Photochemotherapy/methods ; SARS-CoV-2 ; Taste Disorders/etiology
    Language English
    Publishing date 2021-11-24
    Publishing country Netherlands
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2021.102643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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