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Book ; Online: COVID-19. Normas de Orientação Clínica - Medicina Dentária

2020

Size	1 electronic resource (180 pages)
Publisher	Coimbra University Press
Document type	Book ; Online
Note	Dental Medicine, Dentistry Guidelines, Evidence based Medicine, SARS CoV 2 , Covid 19 ; Open Access
HBZ-ID	HT020589140
ISBN	9789892619859 ; 9892619854
DOI	10.14195/978-989-26-1986-6
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: A Working Definition of Fake News

João Pedro Baptista / Anabela Gradim

Encyclopedia, Vol 2, Iss 43, Pp 632-

2022 Volume 645

Abstract: Current literature on fake news is rather abundant and mainly focused on history, variety, and types, rather than processes. This review draws on current literature to build a working definition of fake news focused on its present relevance to journalism ...

Abstract	Current literature on fake news is rather abundant and mainly focused on history, variety, and types, rather than processes. This review draws on current literature to build a working definition of fake news focused on its present relevance to journalism and political communication contemporary debate, distinguishing it from non-pertinent conceptual varieties and contributing to a much-needed clarification on the subject. We performed a qualitative analysis of the literature published between 2016 and 2020. Data were extracted from Web of Science and Scopus. We define fake news as a type of online disinformation with misleading and/or false statements that may or may not be associated with real events, intentionally designed to mislead and/or manipulate a specific or imagined public through the appearance of a news format with an opportunistic structure (title, image, content) to attract the reader’s attention in order to obtain more clicks and shares and, therefore, greater advertising revenue and/or ideological gain.
Keywords	fake news ; disinformation ; post-truth ; Science ; Q
Subject code	070
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hemoglobin in large vessel occlusion: Look further than collaterals.

Ramos, João Nuno / Calvão-Pires, Pedro / Gil, Inês / Baptista, Tiago / Branco, Cristina / Branco, Gabriel / Marto, João Pedro

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2024 Volume 121, Page(s) 100–104

Abstract: Background: Abnormal hemoglobin (Hb) levels lead to poorer outcomes in ischemic stroke, though the mechanisms remain elusive. We aimed to study the role of Hb on imaging and clinical outcomes, namely on collaterals as it is a known mediator of infarct ... ...

Abstract	Background: Abnormal hemoglobin (Hb) levels lead to poorer outcomes in ischemic stroke, though the mechanisms remain elusive. We aimed to study the role of Hb on imaging and clinical outcomes, namely on collaterals as it is a known mediator of infarct growth. Methods: Retrospective cohort study of patients with large vessel occlusion ischemic stroke admitted to our center. Demographics, clinical and imaging variables were collected, particularly baseline hemoglobin, presence of anemia and collateral score. Collaterals were scored from 0 to 3 and defined as poor if 0-1. Multivariable analyses were performed for collateral score and clinical outcomes (3-month mortality and good prognosis). Results: We included 811 patients, 215 (26.5 %) with anemia. Patients with anemia were older, had more comorbidities and more severe strokes. Hemoglobin levels and anemia were not associated with collateral score (OR 0.97, 95 % CI 0.89-1.05, p = 0.414 and OR 0.89, 95 % CI 0.64-1.24, p = 0.487, respectively) nor with poor collaterals (OR 0.96, 95 % CI 0.88-1.05, p = 0.398 and OR 0.86, 95 % CI 0.60-1.23, p = 0.406, respectively). Hb levels were associated with 3-month mortality (OR 0.85, 95 % CI 0.76-0.96, p = 0.008). Conclusion: Hemoglobin or anemia were not found to be associated with collateral status. Our results raise further questions regarding the pathophysiology of anemia and outcomes in ischemic stroke, highlighting the need for future research.
MeSH term(s)	Humans ; Brain Ischemia/complications ; Brain Ischemia/diagnostic imaging ; Retrospective Studies ; Stroke/diagnostic imaging ; Arterial Occlusive Diseases ; Ischemic Stroke ; Hemoglobins ; Anemia/complications ; Collateral Circulation/physiology ; Cerebral Angiography/methods ; Treatment Outcome
Chemical Substances	Hemoglobins
Language	English
Publishing date	2024-02-20
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2024.02.010
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Zs.A 3999: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Intraocular lens power calculation: angle κ and ocular biomechanics.

Marques, João Heitor / Baptista, Pedro Manuel / Ribeiro, Bruno / Menéres, Pedro / Beirão, João Melo

Journal of cataract and refractive surgery

2023 Volume 50, Issue 4, Page(s) 345–351

Abstract: Purpose: To study the effect of ocular biomechanics on the prediction error of intraocular lens (IOL) power calculation.: Setting: Centro Hospitalar Universitário do Porto, Porto, Portugal.: Design: Prospective longitudinal study.: Methods: ... ...

Abstract	Purpose: To study the effect of ocular biomechanics on the prediction error of intraocular lens (IOL) power calculation. Setting: Centro Hospitalar Universitário do Porto, Porto, Portugal. Design: Prospective longitudinal study. Methods: This study included 67 subjects. Before cataract surgery subjects underwent biometry with IOLMaster 700 and biomechanical analysis with Corvis Scheimpflug technology. The targeted spherical equivalent was calculated with SRK-T and Barrett Universal II. Associations between prediction error (PE), absolute prediction error (AE), and biometric and biomechanical parameters were performed with stepwise multivariate linear correlation analysis. Results: Using the SRKT formula, there was association between PE and Corvis Biomechanical Index (CBI, B = -0.531, P = .011) and between AE and the horizontal offset between the center of the pupil and the visual axis (angle κ, B = -0.274, P = .007). Considering the Barret Universal II formula, PE was independently associated with anterior chamber depth ( B = -0.279, P = .021) and CBI ( B = -0.520, P = .013) and AE was associated with angle κ ( B = -0.370, P = .007). Conclusions: A large angle κ may reduce the predictability of IOL power calculation. Ocular biomechanics likely influence the refractive outcomes after IOL implantation. This study showed that eyes with softer corneal biomechanics had more myopic PE. This may relate to anteriorization of the effective lens position. Dynamic measurements may be the way to progress into future formulas.
MeSH term(s)	Humans ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Visual Acuity ; Prospective Studies ; Biomechanical Phenomena ; Longitudinal Studies ; Refraction, Ocular ; Biometry ; Retrospective Studies ; Optics and Photonics ; Phacoemulsification
Language	English
Publishing date	2023-11-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	632744-8
ISSN	1873-4502 ; 0886-3350
ISSN (online)	1873-4502
ISSN	0886-3350
DOI	10.1097/j.jcrs.0000000000001362
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1806: Show issues

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Book ; Online: Cancer Nanotheranostics: What Have We Learned So Far?

Tian, Furong / Fuente, Jesus M. De La / Baptista, Pedro Viana / Conde, Joao

2016

Abstract: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease ... ...

Abstract	After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer.- Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action.- These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments.-
Keywords	Chemistry ; Science (General)
Size	1 electronic resource (128 p.)
Publisher	Frontiers Media SA
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT020091202
ISBN	9782889197767 ; 288919776X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Renal function in the ICU: always look both ways before initiating venous thromboprophylaxis.

Baptista, João Pedro / Silva, Catarina Mendes / Baptista, Laura / Nogueira, Joana / Martins, Paulo

Intensive care medicine

2023 Volume 49, Issue 7, Page(s) 896–897

MeSH term(s)	Humans ; Anticoagulants/therapeutic use ; Venous Thromboembolism/prevention & control ; Venous Thromboembolism/drug therapy ; Heparin, Low-Molecular-Weight/therapeutic use ; Intensive Care Units ; Kidney/physiology
Chemical Substances	Anticoagulants ; Heparin, Low-Molecular-Weight
Language	English
Publishing date	2023-04-27
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	80387-x
ISSN	1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
ISSN (online)	1432-1238
ISSN	0340-0964 ; 0342-4642 ; 0935-1701
DOI	10.1007/s00134-023-07069-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1089: Show issues

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Article: Corticosteroid Therapy in Severe Cases of Pneumonia Caused by SARS-CoV-2.

Alves, João / Salgueiro, Andrea / Baptista, João Pedro / Martins, Paulo

Cureus

2022 Volume 14, Issue 12, Page(s) e33076

Abstract: We present a case of severe pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 63-year-old woman needing venous oxygenation by an extracorporeal membrane. Given the difficult clinical resolution with persistent ... ...

Abstract	We present a case of severe pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 63-year-old woman needing venous oxygenation by an extracorporeal membrane. Given the difficult clinical resolution with persistent inflammatory parameters, treatment with corticosteroids (methylprednisolone) was prescribed. The clinical evolution observed, namely the improvement of respiratory and imaging parameters, reiterates the recommendations of corticosteroids for moderate to severe disease.
Language	English
Publishing date	2022-12-29
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.33076
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Phlegmasia cerulea dolens: a swelling, cyanosis and discolouration of the extremity in the ICU.

Alves, João / Salgueiro, Andrea / Baptista, João Pedro / Coimbra, Paulo

BMJ case reports

2022 Volume 15, Issue 11

Abstract: Phlegmasia cerulea dolens is a rare entity that causes critical limb ischaemia, which may lead to amputation of the limb and may be life-threatening. Here, we describe a case of a healthy man in his 50s with multiple trauma who was transferred to the ... ...

Abstract	Phlegmasia cerulea dolens is a rare entity that causes critical limb ischaemia, which may lead to amputation of the limb and may be life-threatening. Here, we describe a case of a healthy man in his 50s with multiple trauma who was transferred to the intensive care unit (ICU) of a central hospital for neuromonitoring following splenectomy for the stabilisation of a hypovolaemic shock. On admission to the ICU, the patient developed a swollen and white leg. The condition was caused by early compromised arterial flow secondary to extensive deep vein thrombosis.
MeSH term(s)	Male ; Humans ; Cyanosis/etiology ; Edema ; Extremities ; Intensive Care Units ; Venous Thrombosis/complications ; Venous Thrombosis/surgery
Language	English
Publishing date	2022-11-29
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2022-251973
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Are we missing an opportunity? Prehospital delay in patients with acute ischemic stroke and known atrial fibrillation.

Magriço, Marta / Serôdio, Miguel / Ramos, João Nuno / Ventura, Rita / Sobral-Pinho, André / Marto, João Pedro / Viana-Baptista, Miguel

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

2024

Abstract: Introduction and objectives: The follow-up of patients with atrial fibrillation (AF) presents an opportunity to alert patients and their families on how to recognize and act in the event of stroke. Our aim was to compare stroke recognition-to-door time ... ...

Abstract	Introduction and objectives: The follow-up of patients with atrial fibrillation (AF) presents an opportunity to alert patients and their families on how to recognize and act in the event of stroke. Our aim was to compare stroke recognition-to-door time and prehospital stroke code activation in patients with known AF (KAF) and AF detected after stroke (AFDAS). Methods: We performed a retrospective cohort study of consecutive patients receiving acute recanalization treatment for acute ischemic stroke between January 2016 and August 2022, with AF as a potential stroke cause. Patients were divided into KAF and AFDAS, and stroke recognition-to-door time and prehospital stroke code activation were compared. In the KAF subgroup, we assessed whether the use of preadmission anticoagulation was associated with the studied prehospital parameters. Results: We included 438 patients, 290 female (66.2%), mean age 79.3±9.4 years. In total, 238 patients had KAF (54.3%) and 200 (45.7%) had AFDAS. Of those with KAF, 114 (48.1%) were pretreated with anticoagulation. Patients with KAF and AFDAS had no differences in stroke recognition-to-door time (74.0 [55.0-101.0] vs. 78.0 [60.0-112.0] min; p=0.097) or prehospital stroke code activation [148 (64.6%) vs. 128 (65.3%); p=0.965]. In the KAF subgroup, preadmission anticoagulation did not influence stroke recognition-to-door time or mode of hospital admission. Conclusion: Stroke recognition-to-door time and prehospital stroke code activation were similar between patients with known or newly diagnosed AF. Preadmission anticoagulation treatment also did not affect the studied parameters. Our findings highlight a missed opportunity to promote stroke knowledge in patients followed due to AF.
Language	Portuguese
Publishing date	2024-02-21
Publishing country	Portugal
Document type	Journal Article
ZDB-ID	632718-7
ISSN	2174-2030 ; 0870-2551 ; 0304-4750
ISSN (online)	2174-2030
ISSN	0870-2551 ; 0304-4750
DOI	10.1016/j.repc.2023.11.005
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Zs.B 2865: Show issues

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Article ; Online: Fact-checking

João Pedro Baptista / Anabela Gradim / Marlene Loureiro / Fábio Ribeiro

Disertaciones, Vol 16, Iss

uma prática recente em Portugal? Análise da perceção da audiência

2023 Volume 1

Abstract: O fact-checking é uma prática jornalística muito recente em Portugal. Nenhum estudo até agora procurou entender a atitude do público em relação a este novo fenómeno. Metodologia: este estudo exploratório, com base em um questionário online (N = 618), ... ...

Abstract	O fact-checking é uma prática jornalística muito recente em Portugal. Nenhum estudo até agora procurou entender a atitude do público em relação a este novo fenómeno. Metodologia: este estudo exploratório, com base em um questionário online (N = 618), teve como objetivo investigar a atitude e a perceção dos portugueses em relação ao fact-checking, analisando o efeito das práticas de consumo de informação, os aspetos sociodemográficos e a orientação política dos indivíduos. Os nossos resultados mostram que a maioria é favorável ao fact-checking e está familiarizada com a prática. No entanto, os níveis de familiaridade são reduzidos e estão abaixo do esperado, uma vez que 40 % dos entrevistados não conhecem este género jornalístico. Além disso, encontramos um ceticismo significativo, por parte dos participantes, em relação à ética dos fact-checkers. Corroborando com outros estudos, os jovens e os mais instruídos são mais favoráveis e mais familiarizados com o fact-checking. Ao contrário de outros estudos, os nossos resultados não mostram qualquer efeito da orientação política e ideológica sobre os níveis de aceitação e familiaridade. Este estudo levanta vários desafios relevantes, demonstrando que as pessoas podem não estar tão familiarizadas com o fact-checking como seria de esperar e que existe uma grande desconfiança no rigor e imparcialidade dos fact-checkers, o que pode ser um obst áculo à correção da desinformação.
Keywords	desinformação ; fact-checking ; notícias falsas ; jornalismo ; Communication. Mass media ; P87-96 ; Social Sciences ; H
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Universidad del Rosario; Universidad de los Andes de Venezuela; Universidad Complutense de Madrid
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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