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Book ; Conference proceedings: Multifunctional food and traditional ingredients

Gregori, Dario

a competitive marriage ; [the second European-Hong Kong Food & Nutrition Symposium, hosted by the Hong Kong Polytechnic on 9 March 2011 ...]

(International journal of food sciences and nutrition ; 63, S 1)

2012

Event/congress	European Hong Kong Food & Nutrition Symposium (2, 2011, Hongkong)
Author's details	guest ed.: Dario Gregori
Series title	International journal of food sciences and nutrition ; 63, S 1
Collection
Language	English
Size	97 S. : Ill., graph. Darst.
Publisher	Informa UK
Publishing place	London
Publishing country	Great Britain
Document type	Book ; Conference proceedings
HBZ-ID	HT017198647
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
Z 3276 (63,Suppl1)	available for loan (reading room)	Freihandmagazin (U1)

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Book: Foreign bodies injuries in children

Passàli, Desiderio / Gregori, Dario

an update

(International journal of pediatric otorhinolaryngology ; 76, Suppl. 1)

2012

Author's details	guest ed.: Desiderio Passali & Dario Gregori
Series title	International journal of pediatric otorhinolaryngology ; 76, Suppl. 1
Collection
Language	English
Size	S91 S. : Ill., graph. Darst.
Publisher	Elsevier
Publishing place	Amsterdam u.a.
Publishing country	Netherlands
Document type	Book
HBZ-ID	HT017244537
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

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Zs A 1507 -76,Suppl.1-	not available for loan	Zeitschriften-Lesesaal

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Article: Non-inferiority designs in clinical trials for antithrombotic therapy in TAVR patients: did we go too far away by cutting corners?

Lorenzoni, Giulia / Gregori, Dario / Tarantini, Giuseppe

Frontiers in cardiovascular medicine

2024 Volume 11, Page(s) 1327904

Language	English
Publishing date	2024-01-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2024.1327904
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: The ESFBI study final report

Gregori, Dario

(Collana Fondazione "Franca e Diego de Castro" : Statistica Medica)

2005

Institution	European Federation of Societies for ORL, Head and Neck Surgery
Author's details	EUFOS, European Federation of Oto-Rhino-Laryngological Societies ... Ed. by Dario Gregori
Series title	Collana Fondazione "Franca e Diego de Castro" : Statistica Medica
Subject code	616
Language	English
Size	510 S. : Ill.
Publisher	FrancoAngeli
Publishing place	Milano
Publishing country	Italy
Document type	Book
HBZ-ID	HT014566832
ISBN	88-464-6739-6 ; 978-88-464-6739-3
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2006 A 637	order for loan	Magazin

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Article: Minimally invasive left atrial appendage occlusion plus reduced dose direct oral anticoagulant to prevent stroke in patients with atrial fibrillation-the LAAO-PlusRE.

Besola, Laura / Gregori, Dario / Fiocco, Alessandro / Colli, Andrea

Annals of cardiothoracic surgery

2024 Volume 13, Issue 2, Page(s) 146–154

Abstract: The onset of atrial fibrillation (AF) has a direct association with left atrial appendage (LAA) function, as demonstrated by recent studies demonstrating the link between left atrial (LA) wall fibrosis, impaired contractility, and the development of AF. ... ...

Abstract	The onset of atrial fibrillation (AF) has a direct association with left atrial appendage (LAA) function, as demonstrated by recent studies demonstrating the link between left atrial (LA) wall fibrosis, impaired contractility, and the development of AF. Non-valvular AF (NVAF) affects almost 30 million people worldwide, with this number expected to increase in the next 20 years. It is the main cause of ischemic stroke, with significant subsequent economic and social impact. Currently, the mainstay of stroke prevention in patients with NVAF is oral anticoagulation (OAC), which reduces the incidence of ischemic events at the stake of increased hemorrhagic events. Despite the introduction and widespread use of direct oral anticoagulants (DOACs), which almost completely replaced vitamin K antagonists (VKAs), the adherence to OAC is still low, hindering the efficacy of stroke prevention. Percutaneous LAA occlusion (LAAO) is now indicated (class IIB) in patients with NVAF at increased ischemic risk who cannot undergo OAC. Recently published data demonstrated that a reduced dose of DOAC after percutaneous LAAO is superior to long-term dual antiplatelet therapy (DAPT) for stroke prevention in the mid-term. One of the possible pitfalls of percutaneous LAAO is postprocedural peri-device leaks (PDLs) that have been associated with increased thromboembolic events. According to LAAOS III results, surgical LAAO during cardiac surgery brings a 33% reduction in risk of stroke at five years, independently from the OAC regimen with a high rate of complete appendage occlusion. The combination of surgical LAAO and reduced dose DOAC might ensure adequate embolic prevention, lowering the hemorrhagic risk. The present manuscript aims to describe the rationale and design of the Minimally Invasive Left Atrial Appendage Occlusion Plus REduced Dose DOAC To Prevent Stroke In Patients With Atrial Fibrillation Randomized Clinical Trial (LAAO-PlusRE).
Language	English
Publishing date	2024-03-18
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2713627-9
ISSN	2304-1021 ; 2225-319X
ISSN (online)	2304-1021
ISSN	2225-319X
DOI	10.21037/acs-2023-afm-18
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The prophylactic use of negative pressure wound therapy after cardiac surgery: a meta-analysis.

Fiocco, Alessandro / Dini, Martina / Lorenzoni, Giulia / Gregori, Dario / Colli, Andrea / Besola, Laura

The Journal of hospital infection

2024

Abstract: Background: Surgical site infections (SSi) pose a frequent complication in cardiac surgery patients and lead to increased patient discomfort and extended hospitalization.: Aim: This meta-analysis evaluates the protective role of single-use-negative- ... ...

Abstract	Background: Surgical site infections (SSi) pose a frequent complication in cardiac surgery patients and lead to increased patient discomfort and extended hospitalization. Aim: This meta-analysis evaluates the protective role of single-use-negative-pressure-wound-therapy (sNPWT) devices on closed surgical wounds after cardiac surgery, and explores their potential preventive application across all cardiac surgery patients. Methods: A comprehensive literature search was conducted on PubMed and Elsevier, focusing on studies related to "negative pressure wound therapy" or "PICO negative pressure wound therapy" combined with "cardiac surgery" or "sternotomy," published between 2000 and 2022. Inclusion criteria encompassed case-control studies comparing sNPWT with traditional dressing on closed cardiac surgical incisions in adult patients undergoing median sternotomy without immediate postoperative infective complications, with available details on SSIs. A retrospective analysis of cases treated with sNPWT in our Center was also performed. Findings: The meta-analysis revealed a protective role of sNPWT, indicating a 44% risk reduction in overall SSIs (OR 0.56) and a 40% risk reduction in deep wound infections (OR 0.60). Superficial wound infections, however, showed non-significant protective effects. A single-center study aligned with the meta-analysis findings, confirming the efficacy of sNPWT and was included in the meta-analysis. Conclusion: The meta-analysis and the single-centre study collectively support the protective role of negative pressure wound therapy against overall and deep surgical site infections, suggesting its potential prophylactic use on all cardiac surgery population.
Language	English
Publishing date	2024-04-25
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	779366-2
ISSN	1532-2939 ; 0195-6701
ISSN (online)	1532-2939
ISSN	0195-6701
DOI	10.1016/j.jhin.2024.04.003
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Zs.A 1586: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Early coronavirus disease 2019 impact on cardiac surgical emergencies in northeast Italy: hidden collateral damage?

Pradegan, Nicola / Lorenzoni, Giulia / Gregori, Dario / Gerosa, Gino

Journal of cardiovascular medicine (Hagerstown, Md.)

2022 Volume 24, Issue 2, Page(s) 141–142

MeSH term(s)	Humans ; COVID-19/epidemiology ; Emergencies ; SARS-CoV-2 ; Cardiac Surgical Procedures/adverse effects ; Italy/epidemiology
Language	English
Publishing date	2022-11-14
Publishing country	United States
Document type	Letter
ZDB-ID	2223461-5
ISSN	1558-2035 ; 1558-2027
ISSN (online)	1558-2035
ISSN	1558-2027
DOI	10.2459/JCM.0000000000001402
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Zs.A 5210: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 559: Show issues

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Article: Effetti del genere e dell’età sugli eccessi di mortalità durante l’epidemia di COVID-19 in Italia.

Azzolina, Daniela / Magnani, Corrado / Gallo, Elisa / Ferrante, Daniela / Gregori, Dario

Epidemiologia e prevenzione

2021 Volume 44, Issue 5-6 Suppl 2, Page(s) 252–259

Abstract: Background: the COVID-19 epidemic severely affected Italy among European countries causing a considerable number of deaths across the country, especially in Northern Italy, leading also to serious problems to the Italian healthcare system, in particular ...

Title translation	Gender and age factors affecting the mortality during the COVID-19 epidemic in Italy.
Abstract	Background: the COVID-19 epidemic severely affected Italy among European countries causing a considerable number of deaths across the country, especially in Northern Italy, leading also to serious problems to the Italian healthcare system, in particular the overcrowding of Intensive Care Units (ICU). In literature, the debate on the overall mortality during the COVID-19 epidemic, directly and indirectly, associated with the disease, is still open. Objectives: to describe the time trend of the mortality in Italy during the COVID-19 pandemic accounting for age, gender, and geographical areas. Design: analysis of mortality trend, by region, age, and gender. Setting and participants: the Italian mortality data, released by the Italian National Institute of Statistics (Istat), have been considered for the analyses. The data refer to the first four months of 2015-2019 and 2020, involving 7,270 municipalities, corresponding to 93% of the Italian population. Main outcome measures: the mortality rates in the first four months of 2015-2019 and 2020, age-adjusted, have been calculated together with the percent variation. The data were analysed by gender, age class (<65; >=65 years), Region, and geographical areas (Northern versus Central-Southern Italy). The overall daily mortality series have been represented as rates over 100,000 resident population. Results: in addition to the geographical location, the age component was a major determinant of the mortality pattern. The greater increase in the overall mortality was evidenced among elderly subjects in the Northern Italian Regions most affected by the epidemic. In these areas, also gender component played an important role in determining the mortality excess: higher mortality rates in the first four months of 2020 are observed for males in comparison to female populations. Conclusions: this research reveals that the population components are an important issue in determining the COVID-19 mortality excess. For this reason, it is of primary importance to monitor mortality (overall and by COVID-19) by age and gender and to consider these components and the related factors (comorbidity, exposures affecting the lung) in the public prevention policies towards the protection of the most fragile population groups.
MeSH term(s)	Adult ; Age Factors ; Aged ; COVID-19/epidemiology ; COVID-19/mortality ; Cause of Death ; Comorbidity ; Female ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Mortality ; Pandemics ; SARS-CoV-2 ; Sex Factors ; Time Factors
Language	Italian
Publishing date	2021-01-04
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1038112-0
ISSN	1120-9763
ISSN	1120-9763
DOI	10.19191/EP20.5-6.S2.125
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Zs.A 2748: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 265: Show issues

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Article ; Online: Prognostic role of platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte, and lymphocyte-to-monocyte ratio in operated rectal cancer patients: systematic review and meta-analysis.

Portale, Giuseppe / Bartolotta, Patrizia / Azzolina, Danila / Gregori, Dario / Fiscon, Valentino

Langenbeck's archives of surgery

2023 Volume 408, Issue 1, Page(s) 85

Abstract: Background: Inflammation plays an important role in tumor growth. Novel serum blood biomarkers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), have been proposed as useful ... ...

Abstract	Background: Inflammation plays an important role in tumor growth. Novel serum blood biomarkers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), have been proposed as useful prognostic indexes in cancer patients. However, their role in rectal cancer is controversial. Methods: A comprehensive literature review was conducted including MEDLINE/Pubmed, EMBASE, SCOPUS, and the Cochrane Database of Systematic Reviews through May 2022. The systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Quality was appraised with the Methodological Index for Non-Randomized Studies (MINORS) tool. Aim of the study was to summarize available literature on PLR, NLR, and LMR in patients with rectal cancer undergoing resection. Results: Forty-seven observational studies (14,205 patients) were included; there were 42 retrospective and 5 prospective cohort studies with an average MINORS score of 14.6 (range: 12-18). Worse overall survival was associated with high NLR (HR 1.81; 95%CI 1.52-2.15; p < 0.001), high PLR (HR 1.24; 95%CI 1.06-1.46; p = 0.009), and low LMR (HR 0.67; 95%CI 0.49-0.91; p = 0.01). High NLR and low LMR were also associated with disease-free-survival (HR 1.68; 95%CI 1.35-2.08; p < 0.001 and HR 0.71; 95%CI 0.58-0.87; p < 0.001, respectively). Conclusions: NLR, PLR, and LMR are independent clinical predictors for overall survival in patients with rectal cancer treated with curative surgery. NLR and LMR are also good predictors for disease free survival. These biomarkers, which are readily available, appear optimal prognostic indexes and may help clinicians predict the prognosis of rectal cancer and develop individualized treatment strategies.
MeSH term(s)	Humans ; Prognosis ; Neutrophils ; Monocytes ; Retrospective Studies ; Prospective Studies ; Lymphocytes ; Biomarkers ; Rectal Neoplasms/surgery ; Rectal Neoplasms/pathology
Chemical Substances	Biomarkers
Language	English
Publishing date	2023-02-13
Publishing country	Germany
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	1423681-3
ISSN	1435-2451 ; 1435-2443
ISSN (online)	1435-2451
ISSN	1435-2443
DOI	10.1007/s00423-023-02786-8
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Article ; Online: Laparoscopic right hemicolectomy with 2D or 3D video system technology: systematic review and meta-analysis.

Portale, Giuseppe / Bartolotta, Patrizia / Azzolina, Danila / Gregori, Dario / Fiscon, Valentino

International journal of colorectal disease

2023 Volume 38, Issue 1, Page(s) 34

Abstract: Background: Standard laparoscopic colorectal surgery relies on 2D image systems in most centers. However, 3D vision has gained popularity and is used nowadays in a constantly rising number of units. Right hemicolectomy with intracorporeal anastomosis ... ...

Abstract	Background: Standard laparoscopic colorectal surgery relies on 2D image systems in most centers. However, 3D vision has gained popularity and is used nowadays in a constantly rising number of units. Right hemicolectomy with intracorporeal anastomosis and lymph node dissection represents a surgical procedure that may benefit the most from 3D vision. The aim of the study was to summarize the available literature on the use of 2D vs. 3D video imaging in patients undergoing laparoscopic right hemicolectomy. Methods: A comprehensive literature review was conducted including Medline/PubMed, Embase, and Scopus (PROSPERO registration number CRD 42022344764) through October 2022. The systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The risk of bias was evaluated using the ROBINS-I tool. Certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) guidelines and GRADEpro to develop a summary of evidence tables. Random-effects meta-analyses were conducted. Results: Five observational retrospective studies (496 patients, 275 2D and 216 3D) were included. One study was rated as having a critical risk of bias; the remaining had low to moderate risk. 2D laparoscopic right hemicolectomy patients showed longer anastomotic time in 3/3 studies (MD = 3.32; 95%CI, 1.58-5.05; p = 0.002) and an upward trend in operative time in 4/5 studies (MD = 9.98; 95%CI, -1.42, 21.37; p = 0.086) compared to 3D. The two image video systems had similar short-term outcomes, including the number of lymph nodes harvested (MD = -0.67; 95%CI, -2.47, 1.13; p = 0.47), morbidity (OR post-operative complications = 1.12; 95%CI, 0.71-1.77; p = 0.62), and length of stay (MD = 0.27; 95%CI, -0.59, 1.13; p = 0.9). Conclusions: 2D and 2D laparoscopic right hemicolectomy had similar complications rate, with a shorter anastomotic time along with a downward trend in overall operative time for 3D. Larger prospective randomized trials are awaited before definitive conclusions can be drawn.
MeSH term(s)	Humans ; Retrospective Studies ; Prospective Studies ; Colectomy/adverse effects ; Colectomy/methods ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Anastomosis, Surgical/methods ; Treatment Outcome ; Colonic Neoplasms/surgery
Language	English
Publishing date	2023-02-11
Publishing country	Germany
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	84975-3
ISSN	1432-1262 ; 0179-1958
ISSN (online)	1432-1262
ISSN	0179-1958
DOI	10.1007/s00384-023-04342-8
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