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Article ; Online: Long-acting injectable buprenorphine for opioid use disorder: A systematic review of impact of use on social determinants of health.

Martin, Emily / Maher, Hayley / McKeon, Gemma / Patterson, Sue / Blake, Julie / Chen, Kai Yang

2022 Volume 139, Page(s) 108776

Abstract: Objectives: This systematic review synthesizes evidence on both the effects and perspectives of the use of novel long-acting injectable buprenorphine (LAIB) as part of medication-assisted treatment (MAT) and its impact on social determinants of health ( ... ...

Abstract	Objectives: This systematic review synthesizes evidence on both the effects and perspectives of the use of novel long-acting injectable buprenorphine (LAIB) as part of medication-assisted treatment (MAT) and its impact on social determinants of health (SDH), specifically abstinence, accessibility, employment, forensic matters, and gender and social relationships via a framework approach. Methods: The study team searched three databases between January 2010 and June 2020 to identify English-language original research published in peer reviewed journals. This search yielded 9253 papers. A comprehensive search followed by 67 full text publication screenings by two independent reviewers yielded 15 papers meeting inclusion criteria. The study included three randomized control trials, one open label safety study, two case series, and six qualitative papers examining patient perspectives toward the LAIB prior to use. The team assessed the quality of studies via standardized quality assessment tools. Results: The LAIB was positively associated with improvements in abstinence, accessibility, employment, social relationships, and forensic matters. Limited evidence exists on gender equity within the current literature. The qualitative papers highlighted the importance of patients' preferences and individualization of treatment planning to ensure the success of MAT. Conclusion: The quality of evidence was rated as medium or high risk of bias, which does limit interpretation of the results. Overall, the LAIB was positively associated with SDH and should be offered as part of MAT in alignment with the recovery model. Future research should evaluate the implementation and longitudinal impacts of LAI buprenorphine compared to treatment as usual (TAU).
MeSH term(s)	Buprenorphine/therapeutic use ; Humans ; Opioid-Related Disorders/drug therapy ; Social Determinants of Health
Chemical Substances	Buprenorphine (40D3SCR4GZ)
Language	English
Publishing date	2022-03-25
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	605923-5
ISSN	1873-6483 ; 0740-5472
ISSN (online)	1873-6483
ISSN	0740-5472
DOI	10.1016/j.jsat.2022.108776
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Article: Exploring the Opinions of Irish Dairy Farmers Regarding Male Dairy Calves.

Maher, James W / Clarke, AnneMarie / Byrne, Andrew W / Doyle, Rob / Blake, Martin / Barrett, Damien

Frontiers in veterinary science

2021 Volume 8, Page(s) 635565

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-04-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2021.635565
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Reconstruction of a large defect of the glabella and forehead.

Blake, Brett / Maher, Ian

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

2015 Volume 41, Issue 2, Page(s) 280–282

MeSH term(s)	Adult ; Facial Neoplasms/surgery ; Female ; Forehead/surgery ; Histiocytoma, Benign Fibrous/surgery ; Humans ; Mohs Surgery ; Patient Satisfaction ; Reconstructive Surgical Procedures/methods ; Surgical Flaps ; Treatment Outcome
Language	English
Publishing date	2015-02
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1227586-4
ISSN	1524-4725 ; 1076-0512
ISSN (online)	1524-4725
ISSN	1076-0512
DOI	10.1097/DSS.0000000000000205
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Article: Exploring the Opinions of Irish Beef Farmers Regarding Dairy Beef Integration.

Maher, James W / Clarke, AnneMarie / Byrne, Andrew William / Doyle, Rob / Blake, Martin / Cromie, Andrew / Barrett, Damien

Frontiers in veterinary science

2021 Volume 8, Page(s) 660061

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-06-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2021.660061
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Article ; Online: Trilobed flap to close a defect in the soft triangle of the nose.

Blake, Brett / Maher, Ian

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

2013 Volume 39, Issue 12, Page(s) 1927–1930

MeSH term(s)	Carcinoma, Basal Cell/surgery ; Humans ; Male ; Middle Aged ; Mohs Surgery ; Nose Neoplasms/surgery ; Reconstructive Surgical Procedures/methods ; Skin Transplantation ; Surgical Flaps
Language	English
Publishing date	2013-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1227586-4
ISSN	1524-4725 ; 1076-0512
ISSN (online)	1524-4725
ISSN	1076-0512
DOI	10.1111/dsu.12279
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Article ; Online: Improving User Experience of Virtual Health Assistants: Scoping Review.

Curtis, Rachel G / Bartel, Bethany / Ferguson, Ty / Blake, Henry T / Northcott, Celine / Virgara, Rosa / Maher, Carol A

Journal of medical Internet research

2021 Volume 23, Issue 12, Page(s) e31737

Abstract: Background: Virtual assistants can be used to deliver innovative health programs that provide appealing, personalized, and convenient health advice and support at scale and low cost. Design characteristics that influence the look and feel of the virtual ...

Abstract	Background: Virtual assistants can be used to deliver innovative health programs that provide appealing, personalized, and convenient health advice and support at scale and low cost. Design characteristics that influence the look and feel of the virtual assistant, such as visual appearance or language features, may significantly influence users' experience and engagement with the assistant. Objective: This scoping review aims to provide an overview of the experimental research examining how design characteristics of virtual health assistants affect user experience, summarize research findings of experimental research examining how design characteristics of virtual health assistants affect user experience, and provide recommendations for the design of virtual health assistants if sufficient evidence exists. Methods: We searched 5 electronic databases (Web of Science, MEDLINE, Embase, PsycINFO, and ACM Digital Library) to identify the studies that used an experimental design to compare the effects of design characteristics between 2 or more versions of an interactive virtual health assistant on user experience among adults. Data were synthesized descriptively. Health domains, design characteristics, and outcomes were categorized, and descriptive statistics were used to summarize the body of research. Results for each study were categorized as positive, negative, or no effect, and a matrix of the design characteristics and outcome categories was constructed to summarize the findings. Results: The database searches identified 6879 articles after the removal of duplicates. We included 48 articles representing 45 unique studies in the review. The most common health domains were mental health and physical activity. Studies most commonly examined design characteristics in the categories of visual design or conversational style and relational behavior and assessed outcomes in the categories of personality, satisfaction, relationship, or use intention. Over half of the design characteristics were examined by only 1 study. Results suggest that empathy and relational behavior and self-disclosure are related to more positive user experience. Results also suggest that if a human-like avatar is used, realistic rendering and medical attire may potentially be related to more positive user experience; however, more research is needed to confirm this. Conclusions: There is a growing body of scientific evidence examining the impact of virtual health assistants' design characteristics on user experience. Taken together, data suggest that the look and feel of a virtual health assistant does affect user experience. Virtual health assistants that show empathy, display nonverbal relational behaviors, and disclose personal information about themselves achieve better user experience. At present, the evidence base is broad, and the studies are typically small in scale and highly heterogeneous. Further research, particularly using longitudinal research designs with repeated user interactions, is needed to inform the optimal design of virtual health assistants.
MeSH term(s)	Communication ; Exercise ; Humans ; Personal Satisfaction
Language	English
Publishing date	2021-12-21
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2028830-X
ISSN	1438-8871 ; 1439-4456
ISSN (online)	1438-8871
ISSN	1439-4456
DOI	10.2196/31737
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: General practitioner experiences using a low back pain management booklet aiming to decrease non-indicated imaging for low back pain.

Jenkins, Hazel J / Moloney, Niamh A / French, Simon D / Maher, Chris G / Dear, Blake F / Magnussen, John S / Hancock, Mark J

Implementation science communications

2022 Volume 3, Issue 1, Page(s) 71

Abstract: Background: Imaging is overused in the management of low back pain, resulting in overdiagnosis, increased healthcare utilisation, and increased costs. Few effective interventions to decrease inappropriate use have been developed and have typically not ... ...

Abstract	Background: Imaging is overused in the management of low back pain, resulting in overdiagnosis, increased healthcare utilisation, and increased costs. Few effective interventions to decrease inappropriate use have been developed and have typically not been developed using behaviour change theory. An intervention to reduce non-indicated imaging for low back pain was developed using behavioural change theory, incorporating a novel low back pain management booklet to facilitate patient education and reassurance. The aim of this study was to assess the adoption and feasibility of use of the developed intervention within clinical practice and to determine appropriate implementation strategies to address identified barriers to use. Methods: Fourteen general medical practitioners were recruited and trained to use the booklet with low back pain patients over a minimum 5-month period. Quantitative data on use of the booklet were collected and analysed descriptively. Qualitative data on use of the booklet and training session were collected in general medical practitioner interviews and thematically analysed. Barriers to use were identified and mapped to suitable implementation strategies using the Behaviour Change Wheel. Results: Practitioners used the booklet with 73 patients. The booklet was used with 63% of patients presenting with low back pain. Facilitators for using the booklet included patient's requesting imaging and lower practitioner confidence in managing low back pain. Barriers included accessible storage and remembering to use the booklet. Implementation strategies were identified to increase adoption and feasibility of use, including development of a digital version of the booklet. Conclusions: General medical practitioners reported that the low back pain management booklet and training were useful for clinical practice, particularly with patients requesting imaging. Barriers to use were identified and implementation strategies to address these barriers will be incorporated into future effectiveness studies. This study forms one of a series of studies to thoroughly develop and test an intervention to reduce non-indicated imaging for low back pain; a successful intervention would decrease healthcare costs and improve patient management.
Language	English
Publishing date	2022-06-28
Publishing country	England
Document type	Journal Article
ISSN	2662-2211
ISSN (online)	2662-2211
DOI	10.1186/s43058-022-00317-y
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Article: Feasibility of testing the effectiveness of a theory-informed intervention to reduce imaging for low back pain: a pilot cluster randomised controlled trial.

Jenkins, Hazel J / French, Simon D / Young, Anika / Moloney, Niamh A / Maher, Chris G / Magnussen, John S / Dear, Blake F / Hancock, Mark J

Pilot and feasibility studies

2022 Volume 8, Issue 1, Page(s) 249

Abstract: Background: General medical practitioner (GP) recruitment and subsequent data collection in clinical practice are challenging and may limit successful completion of a large-scale trial. The aim of this study was to assess the feasibility of undertaking ... ...

Abstract	Background: General medical practitioner (GP) recruitment and subsequent data collection in clinical practice are challenging and may limit successful completion of a large-scale trial. The aim of this study was to assess the feasibility of undertaking a cluster randomised controlled trial to test an intervention to reduce non-indicated imaging for low back pain in general medical practice. Methods: A pilot cluster randomised controlled trial was performed, with recruitment of GPs and randomisation of GP clinics. All GPs attended a training session and were asked to record low back pain codes in electronic medical records for any low back pain presentations. Intervention group GPs were trained in the use of a patient education booklet to be used during low back pain patient visits. Control group GPs provided usual care. Outcomes for the proposed trial were collected to determine feasibility. GP recruitment was assessed as the proportion of GPs approached who consented to participate. Low back pain imaging outcomes were collected from electronic medical records (counts of patients presenting with low back pain) and from Australian healthcare administrative (Medicare) data (counts of imaging use). GP compliance with study procedures was assessed and qualitative data reported. Results: Thirty-four GP clinics were approached, with four participating (12%). At these clinics, 13/19 (68%) GPs consented to participate, and 10/19 (53%) started the study. Outcome data were collected from medical records for all GPs. Three GPs (30%) withdrew consent to access Medicare data, limiting reporting of imaging outcome measures. Three GPs (30%) self-reported low compliance entering low back pain codes. Conclusions: This pilot cluster randomised controlled trial demonstrated the feasibility of many aspects of a full-scale effectiveness study, while also identifying a number of challenges that need to be resolved. Recommendations related to GP recruitment, study compliance, data collection, and outcome measures were made to increase the success of a future trial. Trial registration: Australia and New Zealand Clinical Trials Register (ANZCTR), Trial ID: ACTRN12619000991112; Registered 11 July 2019, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=376973.
Language	English
Publishing date	2022-12-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2809935-7
ISSN	2055-5784
ISSN	2055-5784
DOI	10.1186/s40814-022-01216-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effectiveness of wearable activity trackers to increase physical activity and improve health: a systematic review of systematic reviews and meta-analyses.

Ferguson, Ty / Olds, Timothy / Curtis, Rachel / Blake, Henry / Crozier, Alyson J / Dankiw, Kylie / Dumuid, Dorothea / Kasai, Daiki / O'Connor, Edward / Virgara, Rosa / Maher, Carol

The Lancet. Digital health

2022 Volume 4, Issue 8, Page(s) e615–e626

Abstract: Wearable activity trackers offer an appealing, low-cost tool to address physical inactivity. This systematic review of systematic reviews and meta-analyses (umbrella review) aimed to examine the effectiveness of activity trackers for improving physical ... ...

Abstract	Wearable activity trackers offer an appealing, low-cost tool to address physical inactivity. This systematic review of systematic reviews and meta-analyses (umbrella review) aimed to examine the effectiveness of activity trackers for improving physical activity and related physiological and psychosocial outcomes in clinical and non-clinical populations. Seven databases (Embase, MEDLINE, Ovid Emcare, Scopus, SPORTDiscus, the Cochrane Library, and Web of Science) were searched from database inception to April 8, 2021. Systematic reviews of primary studies using activity trackers as interventions and reporting physical activity, physiological, or psychosocial outcomes were eligible for inclusion. In total, 39 systematic reviews and meta-analyses were identified, reporting results from 163 992 participants spanning all age groups, from both healthy and clinical populations. Taken together, the meta-analyses suggested activity trackers improved physical activity (standardised mean difference [SMD] 0·3-0·6), body composition (SMD 0·7-2·0), and fitness (SMD 0·3), equating to approximately 1800 extra steps per day, 40 min per day more walking, and reductions of approximately 1 kg in bodyweight. Effects for other physiological (blood pressure, cholesterol, and glycosylated haemoglobin) and psychosocial (quality of life and pain) outcomes were typically small and often non-significant. Activity trackers appear to be effective at increasing physical activity in a variety of age groups and clinical and non-clinical populations. The benefit is clinically important and is sustained over time. Based on the studies evaluated, there is sufficient evidence to recommend the use of activity trackers.
MeSH term(s)	Exercise ; Fitness Trackers ; Humans ; Quality of Life ; Systematic Reviews as Topic
Language	English
Publishing date	2022-06-20
Publishing country	England
Document type	Journal Article ; Review ; Systematic Review
ISSN	2589-7500
ISSN (online)	2589-7500
DOI	10.1016/S2589-7500(22)00111-X
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Article ; Online: Transposition Flaps: Principles and Locations.

Blake, Brett P / Simonetta, Cassandra J / Maher, Ian A

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

2015 Volume 41 Suppl 10, Page(s) S255–64

Abstract: Background: Transposition flaps are frequently used to repair defects of the head and neck after tumor extirpation with Mohs micrographic surgery.: Objective: To review the basic principles underlying single-stage transposition flaps and also their ... ...

Abstract	Background: Transposition flaps are frequently used to repair defects of the head and neck after tumor extirpation with Mohs micrographic surgery. Objective: To review the basic principles underlying single-stage transposition flaps and also their utility relative to location on the head and neck. Materials and methods: A review of the literature on transposition flaps was performed with specific reference to the principles of single-stage transposition flaps, including rhomboid flaps and their variations, multilobed flaps, and the locations where transposition flaps are frequently executed on the head and neck. Results: Numerous articles have been written with regard to the techniques for designing and executing transposition flaps. The primary advantages of transposition flaps include less undermining as compared to large sliding flaps and the superior ability to displace tension away from the defect and from free margins. Optimal cosmesis with these flaps can be achieved with appropriate sizing of flaps (or lobes), appropriate undermining, and meticulous suturing. Conclusion: The versatility of transposition flaps makes them optimal for repair of defects on the head and neck and utilization of the outlined key principles and techniques aid in achieving an aesthetic result.
MeSH term(s)	Dermatologic Surgical Procedures/methods ; Evidence-Based Medicine ; Head and Neck Neoplasms/pathology ; Head and Neck Neoplasms/surgery ; Humans ; Mohs Surgery/methods ; Patient Satisfaction ; Practice Guidelines as Topic ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery ; Surgical Flaps ; Suture Techniques ; Treatment Outcome
Language	English
Publishing date	2015-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1227586-4
ISSN	1524-4725 ; 1076-0512
ISSN (online)	1524-4725
ISSN	1076-0512
DOI	10.1097/DSS.0000000000000479
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