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  1. Article: Promoting osteogenesis and bone regeneration employing icariin-loaded nanoplatforms.

    Mohammadzadeh, Mahsa / Zarei, Masoud / Abbasi, Hossein / Webster, Thomas J / Beheshtizadeh, Nima

    Journal of biological engineering

    2024  Volume 18, Issue 1, Page(s) 29

    Abstract: There is an increasing demand for innovative strategies that effectively promote osteogenesis and enhance bone regeneration. The critical process of bone regeneration involves the transformation of mesenchymal stromal cells into osteoblasts and the ... ...

    Abstract There is an increasing demand for innovative strategies that effectively promote osteogenesis and enhance bone regeneration. The critical process of bone regeneration involves the transformation of mesenchymal stromal cells into osteoblasts and the subsequent mineralization of the extracellular matrix, making up the complex mechanism of osteogenesis. Icariin's diverse pharmacological properties, such as anti-inflammatory, anti-oxidant, and osteogenic effects, have attracted considerable attention in biomedical research. Icariin, known for its ability to stimulate bone formation, has been found to encourage the transformation of mesenchymal stromal cells into osteoblasts and improve the subsequent process of mineralization. Several studies have demonstrated the osteogenic effects of icariin, which can be attributed to its hormone-like function. It has been found to induce the expression of BMP-2 and BMP-4 mRNAs in osteoblasts and significantly upregulate Osx at low doses. Additionally, icariin promotes bone formation by stimulating the expression of pre-osteoblastic genes like Osx, RUNX2, and collagen type I. However, icariin needs to be effectively delivered to bone to perform such promising functions.Encapsulating icariin within nanoplatforms holds significant promise for promoting osteogenesis and bone regeneration through a range of intricate biological effects. When encapsulated in nanofibers or nanoparticles, icariin exerts its effects directly at the cellular level. Recalling that inflammation is a critical factor influencing bone regeneration, icariin's anti-inflammatory effects can be harnessed and amplified when encapsulated in nanoplatforms. Also, while cell adhesion and cell migration are pivotal stages of tissue regeneration, icariin-loaded nanoplatforms contribute to these processes by providing a supportive matrix for cellular attachment and movement. This review comprehensively discusses icariin-loaded nanoplatforms used for bone regeneration and osteogenesis, further presenting where the field needs to go before icariin can be used clinically.
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2391582-1
    ISSN 1754-1611
    ISSN 1754-1611
    DOI 10.1186/s13036-024-00425-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Iran's success in controlling the COVID-19 pandemic.

    Mohammadzadeh, Nima / Shahriary, Mahla / Nasri, Erfan

    Infection control and hospital epidemiology

    2020  Volume 41, Issue 11, Page(s) 1359–1360

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Humans ; Incidence ; Iran/epidemiology ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Public Health/methods ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Letter
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article: Current Status and Future Prospects of Renewable and Sustainable Energy in North America: Progress and Challenges

    Azarpour, Abbas / Mohammadzadeh, Omid / Rezaei, Nima / Zendehboudi, Sohrab

    Energy conversion and management. 2022 June 27,

    2022  

    Abstract: Energy is an important drive for the economic development and social growth. The energy demand has remarkably escalated due to technological developments in various governmental, industrial, and municipal activities. In light of such a fast growth, the ... ...

    Abstract Energy is an important drive for the economic development and social growth. The energy demand has remarkably escalated due to technological developments in various governmental, industrial, and municipal activities. In light of such a fast growth, the fuel prices and control of greenhouse gas emission are the leading driving forces for more effective enhancement in the utilization of renewable energy sources. This reflects the importance of mitigation of global energy demands and climate change, which are the most significant factors in the modern days. In this review paper, a detailed overview in the development and evolution of renewable and sustainable energy supply is provided in terms of their types, characteristics and applications, production processes, advantages, and disadvantages. Moreover, the impacts of the renewable energies on health and environment, along with the relevant policies and regulations are discussed. Further, there is a detailed focus on the emerging technologies, and theoretical and practical challenges in the development of renewable energies are analyzed. Particularly, this review provides information on renewable and sustainable energy status and prospects in North America. Central large-scale technology and distributed configuration of the renewable energies might be improved in the North American countries to effectively utilize the renewable energies to produce electricity, biomass-based fuels, and heating in both local/rural and industrial divisions. In addition to employment opportunities stemmed from manufacturing of the renewable energies, its significant impact on the economic development can be enhanced in all three nations through development of the sources.
    Keywords administrative management ; climate change ; economic development ; electricity ; employment ; energy conversion ; greenhouse gas emissions ; North America
    Language English
    Dates of publication 2022-0627
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2000891-0
    ISSN 0196-8904
    ISSN 0196-8904
    DOI 10.1016/j.enconman.2022.115945
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: A glance at the prevalence of coronavirus disease 19 (COVID-19) in Iran: Strengths and weaknesses.

    Mohammadzadeh, Nima / Shahriary, Mahla / Shirmohammadlou, Neda / Lohrasbi, Vahid

    Infection control and hospital epidemiology

    2020  Volume 41, Issue 12, Page(s) 1479–1482

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Communicable Disease Control/methods ; Communicable Disease Control/organization & administration ; Contact Tracing/methods ; Disease Transmission, Infectious/prevention & control ; Disease Transmission, Infectious/statistics & numerical data ; Humans ; Iran/epidemiology ; Needs Assessment ; Physical Distancing ; Prevalence ; SARS-CoV-2/isolation & purification
    Keywords covid19
    Language English
    Publishing date 2020-05-04
    Publishing country United States
    Document type Letter
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Brief outcome of five decades of battle with infectious diseases in Iran.

    Lohrasbi, Vahid / Mohammadzadeh, Nima / Shirmohammadlou, Neda

    Virusdisease

    2020  Volume 31, Issue 1, Page(s) 10–12

    Abstract: According to WHO health profile, Iran has better situation in controlling some infection disease like leprosy, dengue fever, tularemia and hepatitis B than United States, even though Iran is in a more dangerous area than the USA. Achieving optimum ... ...

    Abstract According to WHO health profile, Iran has better situation in controlling some infection disease like leprosy, dengue fever, tularemia and hepatitis B than United States, even though Iran is in a more dangerous area than the USA. Achieving optimum control for infectious disease in the Middle East requires huge financial costs, equipment and a great time. Some of Iran's actions to control infectious diseases include: special attention of the Iran government to the health issue, training and developing human resources, membership and close cooperation with international organizations like WHO, detecting and monitoring emerging diseases before their arrival and distribution in Iran, expanding and updating national immunization and vaccination program since 1992, national project implementation titled "Health system development plan", supplying and manufacturing most of drugs required in Iran by the Iranian companies as a strategic planning, great coordination between different departments of the MOHME and other relevant institutions to Iran Army and Ministry of Intelligence to prevent the emergence of bioterrorism, and etc. We believe that Iran has obtained an acceptable score in the control of infectious diseases; but it still has very big challenges to reach the ideal level.
    Language English
    Publishing date 2020-01-23
    Publishing country India
    Document type Journal Article
    ZDB-ID 2846993-8
    ISSN 2347-3517 ; 2347-3584
    ISSN (online) 2347-3517
    ISSN 2347-3584
    DOI 10.1007/s13337-019-00565-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comments on the published systematic review and meta-analysis on the increasing antibiotic resistance in Clostridioides difficile.

    Kouhsari, Ebrahim / Mehr, Sara Hayati / Sholeh, Mohammad / Mohammadzadeh, Nima

    Anaerobe

    2020  Volume 61, Page(s) 102141

    MeSH term(s) Clostridium Infections ; Clostridium difficile ; Drug Resistance, Microbial ; Humans
    Language English
    Publishing date 2020-01-20
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2019.102141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4318: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Determination of the Risk Factors for Breast Cancer Survival using the Bayesian Method, Yazd, Iran.

    Pahlevani, Vida / Mohammadzadeh, Morteza / Pahlevani, Nima / Nayeb Zadeh, Vajiheh

    Advanced biomedical research

    2021  Volume 10, Page(s) 35

    Abstract: Background: There are numerous sophisticated studies which have investigated risk factors of breast cancer (BC). The purpose of this paper is to use benefits of Bayesian modeling to involve such prior information in determining factors affecting the ... ...

    Abstract Background: There are numerous sophisticated studies which have investigated risk factors of breast cancer (BC). The purpose of this paper is to use benefits of Bayesian modeling to involve such prior information in determining factors affecting the survival of women with BC in Yazd city.
    Materials and methods: The checklist included the characteristics of the patients and the factors studied. Then, from the records of patients referred to Radiotherapy Center of Shahid Ramezanzadeh, who had BC, from April 2005 to March 2012, the survival of 538 persons was recorded in the census. Data were analyzed by R software version 3.4.2, and 0.05 was considered the significance level.
    Results: The mean age of BC diagnosis was 48.03 ± 11016 years. The Bayesian Cox regression showed that surgery (hazard ratio [HR] =1.631 95% PI; 1.102-2.422), ki67 (HR = 3.260. 95% PI; 1.6308-6.372), stage (HR = 5.620, 95% PI; 4.079-7.731), lymph node (HR = 1.765, 95% PI; 1.127-2.790), and ER (HR = 2. 600 95% PI; 2.023-3.354) were significantly related to survival time.
    Conclusion: The parametric and cox models were compared with standard error, and Cox model was selected as an optimal model. Accordingly, stage, ki67, lymph node, ER, and surgery variables had a positive effect on death hazard.
    Language English
    Publishing date 2021-11-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 2672524-1
    ISSN 2277-9175
    ISSN 2277-9175
    DOI 10.4103/abr.abr_152_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Determination of the risk factors for breast cancer survival using the Bayesian method, Yazd, Iran

    Vida Pahlevani / Morteza Mohammadzadeh / Nima Pahlevani / Vajiheh Nayeb Zadeh

    Advanced Biomedical Research, Vol 10, Iss 1, Pp 35-

    2021  Volume 35

    Abstract: Background: There are numerous sophisticated studies which have investigated risk factors of breast cancer (BC). The purpose of this paper is to use benefits of Bayesian modeling to involve such prior information in determining factors affecting the ... ...

    Abstract Background: There are numerous sophisticated studies which have investigated risk factors of breast cancer (BC). The purpose of this paper is to use benefits of Bayesian modeling to involve such prior information in determining factors affecting the survival of women with BC in Yazd city. Materials and Methods: The checklist included the characteristics of the patients and the factors studied. Then, from the records of patients referred to Radiotherapy Center of Shahid Ramezanzadeh, who had BC, from April 2005 to March 2012, the survival of 538 persons was recorded in the census. Data were analyzed by R software version 3.4.2, and 0.05 was considered the significance level. Results: The mean age of BC diagnosis was 48.03 ± 11016 years. The Bayesian Cox regression showed that surgery (hazard ratio [HR] =1.631 95% PI; 1.102–2.422), ki67 (HR = 3.260. 95% PI; 1.6308–6.372), stage (HR = 5.620, 95% PI; 4.079–7.731), lymph node (HR = 1.765, 95% PI; 1.127–2.790), and ER (HR = 2. 600 95% PI; 2.023–3.354) were significantly related to survival time. Conclusion: The parametric and cox models were compared with standard error, and Cox model was selected as an optimal model. Accordingly, stage, ki67, lymph node, ER, and surgery variables had a positive effect on death hazard.
    Keywords bayesian method ; breast cancer ; regression analysis ; risk factors ; survival analysis ; Medicine ; R ; Biology (General) ; QH301-705.5
    Subject code 616
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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