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  1. Article ; Online: Should We or Should We Not Include Confidence Intervals in COVID-19 Death Forecasting? Evidence from a Survey Experiment

    Daoust, Jean-François / Bastien, Frédérick

    SSRN Electronic Journal ; ISSN 1556-5068

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3703966
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: “Until I Know It’s Safe for Me”

    Eric B. Kennedy / Jean-François Daoust / Jenna Vikse / Vivian Nelson

    Vaccines, Vol 9, Iss 1417, p

    The Role of Timing in COVID-19 Vaccine Decision-Making and Vaccine Hesitancy

    2021  Volume 1417

    Abstract: Managing the COVID-19 pandemic—and other communicable diseases—involves broad societal uptake of vaccines. As has been demonstrated, however, vaccine uptake is often uneven and incomplete across populations. This is a substantial challenge that must be ... ...

    Abstract Managing the COVID-19 pandemic—and other communicable diseases—involves broad societal uptake of vaccines. As has been demonstrated, however, vaccine uptake is often uneven and incomplete across populations. This is a substantial challenge that must be addressed by public health efforts. To this point, significant research has focused on demographic and attitudinal correlates with vaccine hesitancy to understand uptake patterns. In this study, however, we advance understandings of individual decision-making processes involved in vaccine uptake through a mixed-methods investigation of the role of timing in COVID-19 vaccine choices. In the first step, a survey experiment, we find the timing of vaccine rollout (i.e., when a vaccine becomes available to the respondent) has a significant impact on public decision-making. Not only is there a higher level of acceptance when the vaccine becomes available at a later time, but delayed availability is correlated with both lower levels of ‘desire to wait’ and ‘total rejection’ of the vaccine. In a second step, we explore associated qualitative data, finding that temporal expressions (i.e., professing a desire to wait) can serve as a proxy for underlying non-temporal rationales, like concerns around safety, efficacy, personal situations, or altruism. By identifying these patterns, as well as the complexities of underlying factors, through a mixed-methods investigation, we can inform better vaccine-related policy and public messaging, as well as enhance our understanding of how individuals make decisions about vaccines in the context of COVID-19.
    Keywords vaccine ; COVID-19 ; vaccine hesitancy ; risk aversion ; timing ; public health ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: "Until I Know It's Safe for Me": The Role of Timing in COVID-19 Vaccine Decision-Making and Vaccine Hesitancy.

    Kennedy, Eric B / Daoust, Jean-François / Vikse, Jenna / Nelson, Vivian

    Vaccines

    2021  Volume 9, Issue 12

    Abstract: Managing the COVID-19 pandemic-and other communicable diseases-involves broad societal uptake of vaccines. As has been demonstrated, however, vaccine uptake is often uneven and incomplete across populations. This is a substantial challenge that must be ... ...

    Abstract Managing the COVID-19 pandemic-and other communicable diseases-involves broad societal uptake of vaccines. As has been demonstrated, however, vaccine uptake is often uneven and incomplete across populations. This is a substantial challenge that must be addressed by public health efforts. To this point, significant research has focused on demographic and attitudinal correlates with vaccine hesitancy to understand uptake patterns. In this study, however, we advance understandings of individual decision-making processes involved in vaccine uptake through a mixed-methods investigation of the role of
    Language English
    Publishing date 2021-11-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines9121417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Is the Unequal COVID-19 Burden in Canada Due to Unequal Levels of Citizen Discipline across Provinces?

    Daoust, Jean-François / Bélanger, Éric / Dassonneville, Ruth / Lachapelle, Erick / Nadeau, Richard

    Canadian public policy. Analyse de politiques

    2022  Volume 48, Issue 1, Page(s) 124–143

    Abstract: The unequal burden of the coronavirus disease 2019 (COVID-19) crisis (e.g., in terms of infection and death rates) across Canadian provinces is important and puzzling. Some have speculated that differences in levels of citizen compliance with public ... ...

    Abstract The unequal burden of the coronavirus disease 2019 (COVID-19) crisis (e.g., in terms of infection and death rates) across Canadian provinces is important and puzzling. Some have speculated that differences in levels of citizen compliance with public health preventive measures are central to understanding cross-provincial differences in pandemic-related health outcomes. However, no systematic empirical test of this hypothesis has been conducted. In this research, we make use of an exceptionally large dataset that includes 23 survey waves (
    Language English
    Publishing date 2022-08-29
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 196490-2
    ISSN 0317-0861
    ISSN 0317-0861
    DOI 10.3138/cpp.2021-060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Citizens' Willingness to Support New Taxes for COVID-19 Measures and the Role of Trust.

    Lachapelle, Erick / Bergeron, Thomas / Nadeau, Richard / Daoust, Jean-François / Dassonneville, Ruth / Bélanger, Éric

    Politics & policy (Statesboro, Ga.)

    2021  Volume 49, Issue 3, Page(s) 534–565

    Abstract: The COVID-19 public health pandemic has seen governments spend trillions of dollars to limit the spread of the COVID-19 virus as well as to soften the economic blow from the shutting down of national economies. Subsequent budget shortfalls raise the ... ...

    Abstract The COVID-19 public health pandemic has seen governments spend trillions of dollars to limit the spread of the COVID-19 virus as well as to soften the economic blow from the shutting down of national economies. Subsequent budget shortfalls raise the question of how governments will pay for the direct and indirect costs associated with the COVID-19 pandemic. In this article, we study the public's willingness to contribute through paying a new tax, with a focus on Canada. We find that both generalized social and political trust are associated with a greater willingness to support a COVID-related tax and that generalized social trust, in particular, attenuates the negative effect of an experimentally manipulated, specified level of tax burden on policy support. These findings entail important implications for the public opinion and tax policies literature, as well as for policy makers.
    Related articles: Gainous, Jason, Stephen C. Craig, and Michael D. Martinez. 2008. "Social Welfare Attitudes and Ambivalence about the Role of Government."
    Language English
    Publishing date 2021-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2227369-4
    ISSN 1747-1346 ; 1555-5623 ; 0730-2177
    ISSN (online) 1747-1346
    ISSN 1555-5623 ; 0730-2177
    DOI 10.1111/polp.12404
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Molecular responses of agroinfiltrated Nicotiana benthamiana leaves expressing suppressor of silencing P19 and influenza virus-like particles.

    Hamel, Louis-Philippe / Tardif, Rachel / Poirier-Gravel, Francis / Rasoolizadeh, Asieh / Brosseau, Chantal / Giroux, Geneviève / Lucier, Jean-François / Goulet, Marie-Claire / Barrada, Adam / Paré, Marie-Ève / Roussel, Élise / Comeau, Marc-André / Lavoie, Pierre-Olivier / Moffett, Peter / Michaud, Dominique / D'Aoust, Marc-André

    Plant biotechnology journal

    2023  Volume 22, Issue 5, Page(s) 1078–1100

    Abstract: The production of influenza vaccines in plants is achieved through transient expression of viral hemagglutinins (HAs), a process mediated by the bacterial vector Agrobacterium tumefaciens. HA proteins are then produced and matured through the secretory ... ...

    Abstract The production of influenza vaccines in plants is achieved through transient expression of viral hemagglutinins (HAs), a process mediated by the bacterial vector Agrobacterium tumefaciens. HA proteins are then produced and matured through the secretory pathway of plant cells, before being trafficked to the plasma membrane where they induce formation of virus-like particles (VLPs). Production of VLPs unavoidably impacts plant cells, as do viral suppressors of RNA silencing (VSRs) that are co-expressed to increase recombinant protein yields. However, little information is available on host molecular responses to foreign protein expression. This work provides a comprehensive overview of molecular changes occurring in Nicotiana benthamiana leaf cells transiently expressing the VSR P19, or co-expressing P19 and an influenza HA. Our data identifies general responses to Agrobacterium-mediated expression of foreign proteins, including shutdown of chloroplast gene expression, activation of oxidative stress responses and reinforcement of the plant cell wall through lignification. Our results also indicate that P19 expression promotes salicylic acid (SA) signalling, a process dampened by co-expression of the HA protein. While reducing P19 level, HA expression also induces specific signatures, with effects on lipid metabolism, lipid distribution within membranes and oxylipin-related signalling. When producing VLPs, dampening of P19 responses thus likely results from lower expression of the VSR, crosstalk between SA and oxylipin pathways, or a combination of both outcomes. Consistent with the upregulation of oxidative stress responses, we finally show that reduction of oxidative stress damage through exogenous application of ascorbic acid improves plant biomass quality during production of VLPs.
    MeSH term(s) Humans ; Influenza, Human ; Influenza Vaccines ; Nicotiana/genetics ; Plants, Genetically Modified/genetics ; Oxylipins/metabolism ; Agrobacterium tumefaciens/genetics ; Orthomyxoviridae/genetics ; Plant Leaves/genetics
    Chemical Substances Influenza Vaccines ; Oxylipins
    Language English
    Publishing date 2023-12-02
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2136367-5
    ISSN 1467-7652 ; 1467-7652
    ISSN (online) 1467-7652
    ISSN 1467-7652
    DOI 10.1111/pbi.14247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: How to survey citizens’ compliance with COVID-19 public health measures. Evidence from three survey experiments

    Daoust, Jean-François Nadeau / Richard, Dassonneville / Ruth, Lachapelle / Erick, Bélanger Éric Savoie / Justin, van der Linden / Clifton,

    Journal of Experimental Political Science

    Abstract: The extent to which citizens comply with newly-enacted public health measures such as social distancing or lockdowns strongly affects the propagation of the virus and the number of deaths from COVID-19 It is however very difficult to identify non- ... ...

    Abstract The extent to which citizens comply with newly-enacted public health measures such as social distancing or lockdowns strongly affects the propagation of the virus and the number of deaths from COVID-19 It is however very difficult to identify non-compliance through survey research because claiming to follow the rules is socially desirable Using three survey experiments, we examine the efficacy of different “face-saving” questions that aim to reduce social desirability in the measurement of compliance with public health measures Our treatments soften the social norm of compliance by way of a short preamble in combination with a guilty-free answer choice making it easier for respondents to admit non-compliance We find that self-reported non-compliance increases by up to +11 percentage points when making use of a face-saving question Considering the current context and the importance of measuring non-compliance, we argue that researchers around the world should adopt our most efficient face-saving question
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #678453
    Database COVID19

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  8. Article ; Online: A guilt-free strategy increases self-reported non-compliance with COVID-19 preventive measures: Experimental evidence from 12 countries.

    Daoust, Jean-François / Bélanger, Éric / Dassonneville, Ruth / Lachapelle, Erick / Nadeau, Richard / Becher, Michael / Brouard, Sylvain / Foucault, Martial / Hönnige, Christoph / Stegmueller, Daniel

    PloS one

    2021  Volume 16, Issue 4, Page(s) e0249914

    Abstract: Studies of citizens' compliance with COVID-19 preventive measures routinely rely on survey data. While such data are essential, public health restrictions provide clear signals of what is socially desirable in this context, creating a potential source of ...

    Abstract Studies of citizens' compliance with COVID-19 preventive measures routinely rely on survey data. While such data are essential, public health restrictions provide clear signals of what is socially desirable in this context, creating a potential source of response bias in self-reported measures of compliance. In this research, we examine whether the results of a guilt-free strategy recently proposed to lessen this constraint are generalizable across twelve countries, and whether the treatment effect varies across subgroups. Our findings show that the guilt-free strategy is a useful tool in every country included, increasing respondents' proclivity to report non-compliance by 9 to 16 percentage points. This effect holds for different subgroups based on gender, age and education. We conclude that the inclusion of this strategy should be the new standard for survey research that aims to provide crucial data on the current pandemic.
    MeSH term(s) Adult ; COVID-19/prevention & control ; COVID-19/psychology ; Disease Transmission, Infectious/prevention & control ; Female ; Guilt ; Humans ; Male ; Middle Aged ; Pandemics ; Patient Compliance/psychology ; SARS-CoV-2/isolation & purification ; Self Report/statistics & numerical data ; Surveys and Questionnaires
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0249914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: How to survey citizens’ compliance with COVID-19 public health measures? Evidence from three survey experiments

    Daoust, Jean-François / Nadeau, Richard / Dassonneville, Ruth / Lachapelle, Erick / Bélanger, Éric / Savoie, Justin / van der Linden, Clifton

    2020  

    Abstract: The extent to which citizens comply with newly-enacted public health measures such as social distancing or lockdowns strongly affects the propagation of the virus and the number of deaths from COVID-19. It is however very difficult to identify non- ... ...

    Abstract The extent to which citizens comply with newly-enacted public health measures such as social distancing or lockdowns strongly affects the propagation of the virus and the number of deaths from COVID-19. It is however very difficult to identify non-compliance through survey research because claiming to follow the rules is socially desirable. Using three survey experiments, we examine the efficacy of different “face-saving” questions that aim to reduce social desirability in the measurement of compliance with public health measures. Our treatments soften the social norm of compliance by way of a short preamble in combination with a guilty-free answer choice making it easier for respondents to admit non-compliance. We find that self-reported non-compliance increases by up to 11 percentage points when making use of a face-saving question. Considering the current context and the importance of measuring non-compliance, we argue that researchers around the world should adopt our most efficient face-saving question.
    Keywords covid19
    Publisher Center for Open Science
    Publishing country us
    Document type Book ; Online
    DOI 10.31235/osf.io/gursd
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: How to Survey Citizens’ Compliance with COVID-19 Public Health Measures

    Daoust, Jean-François / Nadeau, Richard / Dassonneville, Ruth / Lachapelle, Erick / Bélanger, Éric / Savoie, Justin / van der Linden, Clifton

    Journal of Experimental Political Science

    Evidence from Three Survey Experiments

    2020  , Page(s) 1–8

    Abstract: Abstract The extent to which citizens comply with newly enacted public health measures such as social distancing or lockdowns strongly affects the propagation of the virus and the number of deaths from COVID-19. It is however very difficult to identify ... ...

    Abstract Abstract The extent to which citizens comply with newly enacted public health measures such as social distancing or lockdowns strongly affects the propagation of the virus and the number of deaths from COVID-19. It is however very difficult to identify non-compliance through survey research because claiming to follow the rules is socially desirable. Using three survey experiments, we examine the efficacy of different ‘face-saving’ questions that aim to reduce social desirability in the measurement of compliance with public health measures. Our treatments soften the social norm of compliance by way of a short preamble in combination with a guilty-free answer choice making it easier for respondents to admit non-compliance. We find that self-reported non-compliance increases by up to +11 percentage points when making use of a face-saving question. Considering the current context and the importance of measuring non-compliance, we argue that researchers around the world should adopt our most efficient face-saving question.
    Keywords covid19
    Language English
    Publisher Cambridge University Press (CUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2765224-5
    ISSN 2052-2649 ; 2052-2630
    ISSN (online) 2052-2649
    ISSN 2052-2630
    DOI 10.1017/xps.2020.25
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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