LIVIVO - Search results -

Search results

Result 1 - 10 of total 27206

Article ; Online: C

Yang, Jeehyun / Smith, Mica C / Prendergast, Matthew B / Chu, Te-Chun / Green, William H

Physical chemistry chemical physics : PCCP

2021 Volume 23, Issue 26, Page(s) 14325–14339

Abstract: The formation of polycyclic aromatic hydrocarbons (PAHs) during combustion has a substantial impact on environmental pollution and public health. The hydrogen-abstraction-acetylene-addition (HACA) mechanism is expected to be a significant source of ... ...

Abstract	The formation of polycyclic aromatic hydrocarbons (PAHs) during combustion has a substantial impact on environmental pollution and public health. The hydrogen-abstraction-acetylene-addition (HACA) mechanism is expected to be a significant source of larger PAHs containing more than two rings. In this study, the reactions of 1-naphthalenyl and 2-naphthalenyl radicals with acetylene (C2H2) are investigated using VUV photoionization time-of-flight mass spectrometry at 500 to 800 K, 15 to 50 torr, and reaction times up to 10 ms. Our experimental conditions allow us to probe the Bittner-Howard and modified Frenklach HACA routes, but not routes that require multiple radicals to drive the chemistry. The kinetic measurements are compared to a temperature-dependent kinetic model constructed using quantum chemistry calculations and accounting for chemical-activation and fall-off effects. We measure significant quantities of C14H10 (likely phenanthrene and anthracene), as well as 2-ethynylnaphthalene (C12H8), from the reaction of the 2-naphthalenyl radical with C2H2; these results are consistent with the predictions of the kinetic model and the HACA mechanism, but contradict a previous experimental study that indicated no C14H10 formation in the 2-naphthalenyl + C2H2 reaction. In the 1-naphthalenyl radical + C2H2 reaction system, the primary product measured is C12H8, consistent with the predicted formation of acenaphthylene via HACA. The present work provides direct experimental evidence that single-radical HACA can be an important mechanism for the formation of PAHs larger than naphthalene, validating a common assumption in combustion models.
Language	English
Publishing date	2021-06-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d1cp01565f
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: A Redox Transmetalation Step in Nickel-Catalyzed C-C Coupling Reactions.

Green, Kerry-Ann / Honeycutt, Aaron P / Ciccone, Sierra R / Grice, Kyle A / Baur, Andreas / Petersen, Jeffrey L / Hoover, Jessica M

ACS catalysis

2023 Volume 13, Issue 9, Page(s) 6375–6381

Abstract: Ni-catalyzed C-H functionalization reactions are becoming efficient routes to access a variety ... of functionalized arenes, yet the mechanisms of these catalytic C-C coupling reactions are not well understood. Here ... step. Additionally, treatment with electrophilic coupling partners generates C-C and C-S bonds ...

Abstract	Ni-catalyzed C-H functionalization reactions are becoming efficient routes to access a variety of functionalized arenes, yet the mechanisms of these catalytic C-C coupling reactions are not well understood. Here, we report the catalytic and stoichiometric arylation reactions of a nickel(II) metallacycle. Treatment of this species with silver(I)-aryl complexes results in facile arylation, consistent with a redox transmetalation step. Additionally, treatment with electrophilic coupling partners generates C-C and C-S bonds. We anticipate that this redox transmetalation step may be relevant to other coupling reactions that employ silver salts as additives.
Language	English
Publishing date	2023-04-24
Publishing country	United States
Document type	Journal Article
ISSN	2155-5435
ISSN	2155-5435
DOI	10.1021/acscatal.2c06015
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning.

Izquierdo, Patricia G / Charvet, Claude L / Neveu, Cedric / Green, A Christopher / Tattersall, John E H / Holden-Dye, Lindy / O'Connor, Vincent

PloS one

2023 Volume 18, Issue 4, Page(s) e0284786

Abstract: ... stimulation of acetylcholine receptors. Here, we use the organophosphate paraoxon-ethyl to treat C. elegans ...

Abstract	Organophosphate intoxication via acetylcholinesterase inhibition executes neurotoxicity via hyper stimulation of acetylcholine receptors. Here, we use the organophosphate paraoxon-ethyl to treat C. elegans and use its impact on pharyngeal pumping as a bio-assay to model poisoning through these neurotoxins. This assay provides a tractable measure of acetylcholine receptor mediated contraction of body wall muscle. Investigation of the time dependence of organophosphate treatment and the genetic determinants of the drug-induced inhibition of pumping highlight mitigating modulation of the effects of paraoxon-ethyl. We identified mutants that reduce acetylcholine receptor function protect against the consequence of intoxication by organophosphates. Data suggests that reorganization of cholinergic signalling is associated with organophosphate poisoning. This reinforces the under investigated potential of using therapeutic approaches which target a modulation of nicotinic acetylcholine receptor function to treat the poisoning effects of this important class of neurotoxins.
MeSH term(s)	Animals ; Organophosphate Poisoning/drug therapy ; Paraoxon/therapeutic use ; Paraoxon/toxicity ; Cholinesterase Inhibitors/therapeutic use ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Acetylcholinesterase/metabolism ; Receptors, Nicotinic/genetics ; Neurotoxins ; Organophosphates/toxicity ; Organophosphates/therapeutic use
Chemical Substances	ethylparaoxon ; Paraoxon (Q9CX8P80JW) ; Cholinesterase Inhibitors ; Acetylcholinesterase (EC 3.1.1.7) ; Receptors, Nicotinic ; Neurotoxins ; Organophosphates
Language	English
Publishing date	2023-04-21
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0284786
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Iron-Catalyzed Hydrobenzylation: Stereoselective Synthesis of (-)-Eugenial C.

Gan, Xu-Cheng / Kotesova, Simona / Castanedo, Alberto / Green, Samantha A / Møller, Søren Lau Borcher / Shenvi, Ryan A

Journal of the American Chemical Society

2023 Volume 145, Issue 29, Page(s) 15714–15720

Abstract: Metal-hydride hydrogen atom transfer (MHAT) has emerged as a useful tool to form quaternary carbons from alkenes via hydrofunctionalization. Methods to date that cross-couple alkenes with ... ...

Abstract	Metal-hydride hydrogen atom transfer (MHAT) has emerged as a useful tool to form quaternary carbons from alkenes via hydrofunctionalization. Methods to date that cross-couple alkenes with sp
Language	English
Publishing date	2023-07-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c05428
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 55/32: Show issues
Z 7.3: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.

Adhikari, Neill K J / Hashmi, Madiha / Tirupakuzhi Vijayaraghavan, Bharath Kumar / Haniffa, Rashan / Beane, Abi / Webb, Steve A / Angus, Derek C / Gordon, Anthony C / Cook, Deborah J / Guyatt, Gordon H / Berry, Lindsay R / Lorenzi, Elizabeth / Mouncey, Paul R / Au, Carly / Pinto, Ruxandra / Ménard, Julie / Sprague, Sheila / Masse, Marie-Hélène / Huang, David T /

Heyland, Daren K / Nichol, Alistair D / McArthur, Colin J / de Man, Angelique / Al-Beidh, Farah / Annane, Djillali / Anstey, Matthew / Arabi, Yaseen M / Battista, Marie-Claude / Berry, Scott / Bhimani, Zahra / Bonten, Marc J M / Bradbury, Charlotte A / Brant, Emily B / Brunkhorst, Frank M / Burrell, Aidan / Buxton, Meredith / Cecconi, Maurizio / Cheng, Allen C / Cohen, Dian / Cove, Matthew E / Day, Andrew G / Derde, Lennie P G / Detry, Michelle A / Estcourt, Lise J / Fagbodun, Elizabeth O / Fitzgerald, Mark / Goossens, Herman / Green, Cameron / Higgins, Alisa M / Hills, Thomas E / Ichihara, Nao / Jayakumar, Devachandran / Kanji, Salmaan / Khoso, Muhammad Nasir / Lawler, Patrick R / Lewis, Roger J / Litton, Edward / Marshall, John C / McAuley, Daniel F / McGlothlin, Anna / McGuinness, Shay P / McQuilten, Zoe K / McVerry, Bryan J / Murthy, Srinivas / Parke, Rachael L / Parker, Jane C / Reyes, Luis Felipe / Rowan, Kathryn M / Saito, Hiroki / Salahuddin, Nawal / Santos, Marlene S / Saunders, Christina T / Seymour, Christopher W / Shankar-Hari, Manu / Tolppa, Timo / Trapani, Tony / Turgeon, Alexis F / Turner, Anne M / Udy, Andrew A / van de Veerdonk, Frank L / Zarychanski, Ryan / Lamontagne, François

JAMA

2023 Volume 330, Issue 18, Page(s) 1745–1759

Abstract: Importance: The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain ... Objective: To determine whether vitamin C improves outcomes for patients with COVID-19.: Design, setting ... were randomized to receive vitamin C administered intravenously or control (placebo or no vitamin C ...

Abstract	Importance: The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain. Objective: To determine whether vitamin C improves outcomes for patients with COVID-19. Design, setting, and participants: Two prospectively harmonized randomized clinical trials enrolled critically ill patients receiving organ support in intensive care units (90 sites) and patients who were not critically ill (40 sites) between July 23, 2020, and July 15, 2022, on 4 continents. Interventions: Patients were randomized to receive vitamin C administered intravenously or control (placebo or no vitamin C) every 6 hours for 96 hours (maximum of 16 doses). Main outcomes and measures: The primary outcome was a composite of organ support-free days defined as days alive and free of respiratory and cardiovascular organ support in the intensive care unit up to day 21 and survival to hospital discharge. Values ranged from -1 organ support-free days for patients experiencing in-hospital death to 22 organ support-free days for those who survived without needing organ support. The primary analysis used a bayesian cumulative logistic model. An odds ratio (OR) greater than 1 represented efficacy (improved survival, more organ support-free days, or both), an OR less than 1 represented harm, and an OR less than 1.2 represented futility. Results: Enrollment was terminated after statistical triggers for harm and futility were met. The trials had primary outcome data for 1568 critically ill patients (1037 in the vitamin C group and 531 in the control group; median age, 60 years [IQR, 50-70 years]; 35.9% were female) and 1022 patients who were not critically ill (456 in the vitamin C group and 566 in the control group; median age, 62 years [IQR, 51-72 years]; 39.6% were female). Among critically ill patients, the median number of organ support-free days was 7 (IQR, -1 to 17 days) for the vitamin C group vs 10 (IQR, -1 to 17 days) for the control group (adjusted proportional OR, 0.88 [95% credible interval {CrI}, 0.73 to 1.06]) and the posterior probabilities were 8.6% (efficacy), 91.4% (harm), and 99.9% (futility). Among patients who were not critically ill, the median number of organ support-free days was 22 (IQR, 18 to 22 days) for the vitamin C group vs 22 (IQR, 21 to 22 days) for the control group (adjusted proportional OR, 0.80 [95% CrI, 0.60 to 1.01]) and the posterior probabilities were 2.9% (efficacy), 97.1% (harm), and greater than 99.9% (futility). Among critically ill patients, survival to hospital discharge was 61.9% (642/1037) for the vitamin C group vs 64.6% (343/531) for the control group (adjusted OR, 0.92 [95% CrI, 0.73 to 1.17]) and the posterior probability was 24.0% for efficacy. Among patients who were not critically ill, survival to hospital discharge was 85.1% (388/456) for the vitamin C group vs 86.6% (490/566) for the control group (adjusted OR, 0.86 [95% CrI, 0.61 to 1.17]) and the posterior probability was 17.8% for efficacy. Conclusions and relevance: In hospitalized patients with COVID-19, vitamin C had low probability of improving the primary composite outcome of organ support-free days and hospital survival. Trial registration: ClinicalTrials.gov Identifiers: NCT04401150 (LOVIT-COVID) and NCT02735707 (REMAP-CAP).
MeSH term(s)	Humans ; Female ; Middle Aged ; Male ; COVID-19 ; Ascorbic Acid/therapeutic use ; Critical Illness/therapy ; Critical Illness/mortality ; Hospital Mortality ; Bayes Theorem ; Randomized Controlled Trials as Topic ; Vitamins/therapeutic use ; Sepsis/drug therapy
Chemical Substances	Ascorbic Acid (PQ6CK8PD0R) ; Vitamins
Language	English
Publishing date	2023-12-11
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2958-0
ISSN	1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
ISSN (online)	1538-3598
ISSN	0254-9077 ; 0002-9955 ; 0098-7484
DOI	10.1001/jama.2023.21407
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.88: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.

Martinez, Alexis / Lamaizon, Cristian M / Valls, Cristian / Llambi, Fabien / Leal, Nancy / Fitzgerald, Patrick / Guy, Cliff / Kamiński, Marcin M / Inestrosa, Nibaldo C / van Zundert, Brigitte / Cancino, Gonzalo I / Dulcey, Andrés E / Zanlungo, Silvana / Marugan, Juan J / Hetz, Claudio / Green, Douglas R / Alvarez, Alejandra R

Antioxidants (Basel, Switzerland)

2023 Volume 12, Issue 11

Abstract: ... to oxidative stress and mitochondrial fragmentation. Here, we report that endoplasmic reticulum stress activates c-Abl ... c-Abl interacts with and phosphorylates the mitochondrial fusion protein MFN2, resulting ... in mitochondrial fragmentation and apoptosis. Moreover, the pharmacological or genetic inhibition of c-Abl prevents ...

Abstract	The endoplasmic reticulum is a subcellular organelle key in the control of synthesis, folding, and sorting of proteins. Under endoplasmic reticulum stress, an adaptative unfolded protein response is activated; however, if this activation is prolonged, cells can undergo cell death, in part due to oxidative stress and mitochondrial fragmentation. Here, we report that endoplasmic reticulum stress activates c-Abl tyrosine kinase, inducing its translocation to mitochondria. We found that endoplasmic reticulum stress-activated c-Abl interacts with and phosphorylates the mitochondrial fusion protein MFN2, resulting in mitochondrial fragmentation and apoptosis. Moreover, the pharmacological or genetic inhibition of c-Abl prevents MFN2 phosphorylation, mitochondrial fragmentation, and apoptosis in cells under endoplasmic reticulum stress. Finally, in the amyotrophic lateral sclerosis mouse model, where endoplasmic reticulum and oxidative stress has been linked to neuronal cell death, we demonstrated that the administration of c-Abl inhibitor neurotinib delays the onset of symptoms. Our results uncovered a function of c-Abl in the crosstalk between endoplasmic reticulum stress and mitochondrial dynamics via MFN2 phosphorylation.
Language	English
Publishing date	2023-11-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704216-9
ISSN	2076-3921
ISSN	2076-3921
DOI	10.3390/antiox12112007
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus.

Perl, Abbey L / Koetsier, Jennifer L / Green, Kathleen J

Scientific reports

2023 Volume 13, Issue 1, Page(s) 12720

Abstract: ... regulatory motif within the DP C-terminus controlling keratinocyte intercellular adhesion. Here we identify ... the protein phosphatase 2A (PP2A)-B55α holoenzyme as the major serine/threonine phosphatase regulating DP's C ...

Abstract	Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes. The desmosomal cytoplasmic plaque protein desmoplakin (DP) is essential for anchoring IF to the junction. DP-IF interactions are regulated by a phospho-regulatory motif within the DP C-terminus controlling keratinocyte intercellular adhesion. Here we identify the protein phosphatase 2A (PP2A)-B55α holoenzyme as the major serine/threonine phosphatase regulating DP's C-terminus and consequent intercellular adhesion. Using a combination of chemical and genetic approaches, we show that the PP2A-B55α holoenzyme interacts with DP at intercellular membranes in 2D- and 3D- epidermal models and human skin samples. Our experiments demonstrate that PP2A-B55α regulates the phosphorylation status of junctional DP and is required for maintaining strong desmosome-mediated intercellular adhesion. These data identify PP2A-B55α as part of a regulatory module capable of tuning intercellular adhesion strength and a candidate disease target in desmosome-related disorders of the skin and heart.
MeSH term(s)	Humans ; Desmoplakins ; Holoenzymes/metabolism ; Intercellular Junctions/metabolism ; Keratinocytes/metabolism ; Protein Phosphatase 2/metabolism
Chemical Substances	Desmoplakins ; Holoenzymes ; Protein Phosphatase 2 (EC 3.1.3.16) ; PPP2R2A protein, human
Language	English
Publishing date	2023-08-05
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-37874-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Clinical disease characteristics of patients with Niemann-Pick Disease Type C: findings from the International Niemann-Pick Disease Registry (INPDR).

Orphanet journal of rare diseases

2022 Volume 17, Issue 1, Page(s) 51

Abstract: Background: Niemann-Pick Disease Type C (NPC) is an autosomal recessive rare disease characterised ... Among the 97 patients with identified NPC1 variants, the most common variant was the c. 3182T > C variant ...

Abstract	Background: Niemann-Pick Disease Type C (NPC) is an autosomal recessive rare disease characterised by progressive neurovisceral manifestations. The collection of on-going large-scale NPC clinical data may generate better understandings of the natural history of the disease. Here we report NPC patient data from the International Niemann-Pick Disease Registry (INPDR). Method: The INPDR is a web-based, patient-led independent registry for the collection of prospective and retrospective clinical data from Niemann-Pick Disease patients. Baseline data from NPC patients enrolled into the INPDR from September 2014 to December 2019 was extracted to analyse the demographic, genetic and clinical features of the disease. Results: A total of 203 NPC patients from six European countries were included in this study. The mean age (SD) at diagnosis was 11.2 years (14.2). Among enrolled patients, 168 had known neurological manifestations: 43 (24.2%) had early-infantile onset, 47 (26.4%) had late-infantile onset, 41 (23.0%) had juvenile onset, and 37 (20.8%) had adult onset. 10 (5.6%) patients had the neonatal rapidly fatal systemic form. Among the 97 patients with identified NPC1 variants, the most common variant was the c. 3182T > C variant responsible for the p.lle1061Thr protein change, reported in 35.1% (N = 34) of patients. The frequencies of hepatomegaly and neonatal jaundice were greatest in patients with early-infantile and late-infantile neurological onset. Splenomegaly was the most commonly reported observation, including 80% of adult-onset patients. The most commonly reported neurological manifestations were cognitive impairment (78.5%), dysarthria (75.9%), ataxia (75.9%), vertical supranuclear gaze palsy (70.9%) and dysphagia (69.6%). A 6-domain composite disability scale was used to calculate the overall disability score for each neurological form. Across all with neurological onset, the majority of patients showed moderate to severe impairments in all domains, except for 'swallowing' and 'seizure'. The age at diagnosis and death increased with increased age of neurological symptom onset. Miglustat use was recorded in 62.4% of patients and the most common symptomatic therapies used by patients were antiepileptics (32.9%), antidepressants (11.8%) and antacids (9.4%). Conclusion: The proportion of participants at each age of neurological onset was relatively equal across the cohort. Neurological manifestations, such as ataxia, dysphagia, and dysarthria, were frequently observed across all age categories.
MeSH term(s)	Adult ; Child ; Enzyme Inhibitors/therapeutic use ; Humans ; Infant, Newborn ; Niemann-Pick Disease, Type C/drug therapy ; Prospective Studies ; Registries ; Retrospective Studies
Chemical Substances	Enzyme Inhibitors
Language	English
Publishing date	2022-02-14
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2225857-7
ISSN	1750-1172 ; 1750-1172
ISSN (online)	1750-1172
ISSN	1750-1172
DOI	10.1186/s13023-022-02200-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Mechanistic Insights into Iron-Catalyzed C-H Bond Activation and C-C Coupling.

Brewer, Samantha M / Schwartz, Timothy M / Mekhail, Magy A / Turan, Lara S / Prior, Timothy J / Hubin, Timothy J / Janesko, Benjamin G / Green, Kayla N

Organometallics

2021 Volume 40, Issue 15, Page(s) 2467–2477

Abstract: Iron-catalyzed C-C coupling reactions of pyrrole provide a unique alternative to the traditional Pd ...

Abstract	Iron-catalyzed C-C coupling reactions of pyrrole provide a unique alternative to the traditional Pd-catalyzed counterpart. However, many details regarding the actual mechanism remain unknown. A series of macrocyclic iron(III) complexes were used to evaluate specifics related to the role of O
Language	English
Publishing date	2021-07-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2006302-7
ISSN	1520-6041 ; 0276-7333
ISSN (online)	1520-6041
ISSN	0276-7333
DOI	10.1021/acs.organomet.1c00211
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Editorial: How does the risk of hepatocellular carcinoma change over time in patients with a hepatitis C cure? Authors' reply.

Vutien, Philip / Kim, Nicole J / Moon, Andrew M / Johnson, Kay M / Berry, Kristin / Green, Pamela K / Ioannou, George N

Alimentary pharmacology & therapeutics

2024 Volume 59, Issue 3, Page(s) 419–420

MeSH term(s)	Humans ; Carcinoma, Hepatocellular ; Liver Neoplasms ; Hepacivirus ; Hepatitis C/complications ; Hepatitis C/drug therapy
Language	English
Publishing date	2024-01-10
Publishing country	England
Document type	Editorial
ZDB-ID	639012-2
ISSN	1365-2036 ; 0269-2813 ; 0953-0673
ISSN (online)	1365-2036
ISSN	0269-2813 ; 0953-0673
DOI	10.1111/apt.17841
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2206: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito