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  1. Article ; Online: Has the Rajiv Aarogyasri Community Health Insurance Scheme of Andhra Pradesh Addressed the Educational Divide in Accessing Health Care?

    Rao, Mala / Singh, Prabal Vikram / Katyal, Anuradha / Samarth, Amit / Bergkvist, Sofi / Renton, Adrian / Netuveli, Gopalakrishnan

    PloS one

    2016  Volume 11, Issue 1, Page(s) e0145707

    Abstract: ... Rajiv Aarogyasri Community Health Insurance Scheme of Andhra Pradesh state launched in 2007, has ...

    Abstract Background: Equity of access to healthcare remains a major challenge with families continuing to face financial and non-financial barriers to services. Lack of education has been shown to be a key risk factor for 'catastrophic' health expenditure (CHE), in many countries including India. Consequently, ways to address the education divide need to be explored. We aimed to assess whether the innovative state-funded Rajiv Aarogyasri Community Health Insurance Scheme of Andhra Pradesh state launched in 2007, has achieved equity of access to hospital inpatient care among households with varying levels of education.
    Methods: We used the National Sample Survey Organization 2004 survey as our baseline and the same survey design to collect post-intervention data from 8623 households in the state in 2012. Two outcomes, hospitalisation and CHE for inpatient care, were estimated using education as a measure of socio-economic status and transforming levels of education into ridit scores. We derived relative indices of inequality by regressing the outcome measures on education, transformed as a ridit score, using logistic regression models with appropriate weights and accounting for the complex survey design.
    Findings: Between 2004 and 2012, there was a 39% reduction in the likelihood of the most educated person being hospitalised compared to the least educated, with reductions observed in all households as well as those that had used the Aarogyasri. For CHE the inequality disappeared in 2012 in both groups. Sub-group analyses by economic status, social groups and rural-urban residence showed a decrease in relative indices of inequality in most groups. Nevertheless, inequalities in hospitalisation and CHE persisted across most groups.
    Conclusion: During the time of the Aarogyasri scheme implementation inequalities in access to hospital care were substantially reduced but not eliminated across the education divide. Universal access to education and schemes such as Aarogyasri have the synergistic potential to achieve equity of access to healthcare.
    MeSH term(s) Community Health Services ; Female ; Health Education ; Health Equity ; Health Services Accessibility ; Humans ; India ; Insurance, Health ; Male ; Socioeconomic Factors
    Language English
    Publishing date 2016-01-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0145707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Has the Rajiv Aarogyasri Community Health Insurance Scheme of Andhra Pradesh Addressed the Educational Divide in Accessing Health Care?

    Mala Rao / Prabal Vikram Singh / Anuradha Katyal / Amit Samarth / Sofi Bergkvist / Adrian Renton / Gopalakrishnan Netuveli

    PLoS ONE, Vol 11, Iss 1, p e

    2016  Volume 0145707

    Abstract: ... the education divide need to be explored. We aimed to assess whether the innovative state-funded Rajiv ...

    Abstract Equity of access to healthcare remains a major challenge with families continuing to face financial and non-financial barriers to services. Lack of education has been shown to be a key risk factor for 'catastrophic' health expenditure (CHE), in many countries including India. Consequently, ways to address the education divide need to be explored. We aimed to assess whether the innovative state-funded Rajiv Aarogyasri Community Health Insurance Scheme of Andhra Pradesh state launched in 2007, has achieved equity of access to hospital inpatient care among households with varying levels of education.We used the National Sample Survey Organization 2004 survey as our baseline and the same survey design to collect post-intervention data from 8623 households in the state in 2012. Two outcomes, hospitalisation and CHE for inpatient care, were estimated using education as a measure of socio-economic status and transforming levels of education into ridit scores. We derived relative indices of inequality by regressing the outcome measures on education, transformed as a ridit score, using logistic regression models with appropriate weights and accounting for the complex survey design.Between 2004 and 2012, there was a 39% reduction in the likelihood of the most educated person being hospitalised compared to the least educated, with reductions observed in all households as well as those that had used the Aarogyasri. For CHE the inequality disappeared in 2012 in both groups. Sub-group analyses by economic status, social groups and rural-urban residence showed a decrease in relative indices of inequality in most groups. Nevertheless, inequalities in hospitalisation and CHE persisted across most groups.During the time of the Aarogyasri scheme implementation inequalities in access to hospital care were substantially reduced but not eliminated across the education divide. Universal access to education and schemes such as Aarogyasri have the synergistic potential to achieve equity of access to healthcare.
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: A rapid evaluation of the Rajiv Aarogyasri community health insurance scheme in Andhra Pradesh, India

    Sitamma M / Sathyanarayana TN / Rao Mala / Kadam Shridhar / Shidhaye Rahul / Shukla Rajan / Ramachandra Srikrishna / Bandyopadhyay Souvik / Chandran Anil / Anitha CT / George Mathew / Singh Vivek / Sivasankaran Subhashini / Shatrugna Veena

    BMC Proceedings , Vol 6, Iss Suppl 1, p O

    2012  Volume 4

    Keywords Biology (General) ; QH301-705.5 ; Science ; Q ; DOAJ:Biology ; DOAJ:Biology and Life Sciences ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online ; E-Book: Physiology of salt stress in plants

    Singh, Pratibha / Singh, Madhulika / Singh, Rajiv Kumar / Prasad, Sheo Mohan

    perception, signalling, omics and tolerance mechanism

    2022  

    Author's details edited by Pratibha Singh, Madhulika Singh, Rajiv Kumar Singh, Sheo Mohan Prasad
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xvi, 257 Seiten), Illustrationen
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021115630
    ISBN 978-1-119-70048-7 ; 978-1-119-70049-4 ; 9781119700470 ; 1-119-70048-5 ; 1-119-70049-3 ; 1119700477
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Cyclic-NDGA Effectively Inhibits Human γ-Synuclein Fibrillation, Forms Nontoxic Off-Pathway Species, and Disintegrates Preformed Mature Fibrils.

    Singh, Sneh Lata / Bhat, Rajiv

    ACS chemical neuroscience

    2024  

    Abstract: Parkinson's disease arises from protein misfolding, aggregation, and fibrillation and is characterized by LB (Lewy body) deposits, which contain the protein α-synuclein (α-syn) as their major component. Another synuclein, γ-synuclein (γ-syn), coexists ... ...

    Abstract Parkinson's disease arises from protein misfolding, aggregation, and fibrillation and is characterized by LB (Lewy body) deposits, which contain the protein α-synuclein (α-syn) as their major component. Another synuclein, γ-synuclein (γ-syn), coexists with α-syn in Lewy bodies and is also implicated in various types of cancers, especially breast cancer. It is known to seed α-syn fibrillation after its oxidation at methionine residue, thereby contributing in synucleinopathy. Despite its involvement in synucleinopathy, the search for small molecule inhibitors and modulators of γ-syn fibrillation remains largely unexplored. This work reveals the modulatory properties of cyclic-nordihydroguaiaretic acid (cNDGA), a natural polyphenol, on the structural and aggregational properties of human γ-syn employing various biophysical and structural tools, namely, thioflavin T (ThT) fluorescence, Rayleigh light scattering, 8-anilinonaphthalene-1-sulfonic acid binding, far-UV circular dichroism (CD), Fourier transform infrared spectroscopy (FTIR) spectroscopy, atomic force microscopy, ITC, molecular docking, and MTT-toxicity assay. cNDGA was observed to modulate the fibrillation of γ-syn to form off-pathway amorphous species that are nontoxic in nature at as low as 75 μM concentration. The modulation is dependent on oxidizing conditions, with cNDGA weakly interacting (
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.3c00793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Underlying plant trait strategies for understanding the carbon sequestration in Banj oak Forest of Himalaya.

    Singh, Rajat / Pandey, Rajiv

    The Science of the total environment

    2024  Volume 919, Page(s) 170681

    Abstract: Plant functional attributes are subjected to environmental adjustments, which lead to modulations in forest processes under environmental changes. However, a comprehensive assessment of the relationships between plant traits and carbon stock remains ... ...

    Abstract Plant functional attributes are subjected to environmental adjustments, which lead to modulations in forest processes under environmental changes. However, a comprehensive assessment of the relationships between plant traits and carbon stock remains subtle. The present study attempted to accomplish the gap of knowledge by examining the linkages between forest carbon with plant traits within the Banj Oak forest in the Garhwal Himalaya. Twelve individuals from three major species in the Banj Oak forest were randomly selected for trait measurements, and soil samples were collected randomly across the area for evaluation of soil nutrients and carbon. Forest biomass and soil carbon were estimated following standard protocols. A Structural Equation Model (SEM) was applied to establish the relationship between above ground carbon (AGC) and soil organic carbon (SOC) with leaf and stem traits, and soil nutrients. Stem traits were tree height and tree diameter; whereas leaf morphological traits were leaf area, specific leaf area, leaf dry matter content; leaf physiological traits were photosynthesis rate, stomatal conductance, and transpiration rate; and leaf biochemical traits were leaf carbon concentration, leaf nitrogen concentration, and leaf phosphorus concentration. Soil nutrients were available nitrogen, available phosphorus, and exchangeable potassium. Based on SEM results, AGC of the forest was positively correlated with stem traits and leaf physiological traits, while negatively correlated with leaf morphological traits. SOC was positively correlated with soil nutrients and leaf biochemical traits, whereas negatively correlated with stem traits. These findings may support for precise quantification of forest carbon and modeling of forest carbon stocks besides providing inputs to forest managers for devising effective forest management strategies.
    MeSH term(s) Humans ; Carbon ; Quercus ; Carbon Sequestration ; Himalayas ; Soil/chemistry ; Forests ; Trees/physiology ; Nitrogen/analysis ; Phosphorus ; Plant Leaves/chemistry
    Chemical Substances Carbon (7440-44-0) ; Soil ; Nitrogen (N762921K75) ; Phosphorus (27YLU75U4W)
    Language English
    Publishing date 2024-02-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.170681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Introduction: A Multi-Pronged Approach to CKD Associated With Type 2 Diabetes.

    Singh, Ajay K / Agarwal, Rajiv

    Seminars in nephrology

    2023  Volume 43, Issue 3, Page(s) 151444

    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/complications ; Renal Insufficiency, Chronic/complications ; Albuminuria
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2023.151444
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cobalamin C Deficiency: An Uncommon Cause of Hemolytic Uremic Syndrome.

    Singh, Kanika / Pandey, Mukul / Uttam, Rajiv / Sethi, Sidharth Kumar

    Indian pediatrics

    2024  

    Language English
    Publishing date 2024-04-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Recent advances in plant translational genomics for crop improvement.

    Mathur, Shivangi / Singh, Deeksha / Ranjan, Rajiv

    Advances in protein chemistry and structural biology

    2024  Volume 139, Page(s) 335–382

    Abstract: The growing population, climate change, and limited agricultural resources put enormous pressure on agricultural systems. A plateau in crop yields is occurring and extreme weather events and urbanization threaten the livelihood of farmers. It is ... ...

    Abstract The growing population, climate change, and limited agricultural resources put enormous pressure on agricultural systems. A plateau in crop yields is occurring and extreme weather events and urbanization threaten the livelihood of farmers. It is imperative that immediate attention is paid to addressing the increasing food demand, ensuring resilience against emerging threats, and meeting the demand for more nutritious, safer food. Under uncertain conditions, it is essential to expand genetic diversity and discover novel crop varieties or variations to develop higher and more stable yields. Genomics plays a significant role in developing abundant and nutrient-dense food crops. An alternative to traditional breeding approach, translational genomics is able to improve breeding programs in a more efficient and precise manner by translating genomic concepts into practical tools. Crop breeding based on genomics offers potential solutions to overcome the limitations of conventional breeding methods, including improved crop varieties that provide more nutritional value and are protected from biotic and abiotic stresses. Genetic markers, such as SNPs and ESTs, contribute to the discovery of QTLs controlling agronomic traits and stress tolerance. In order to meet the growing demand for food, there is a need to incorporate QTLs into breeding programs using marker-assisted selection/breeding and transgenic technologies. This chapter primarily focuses on the recent advances that are made in translational genomics for crop improvement and various omics techniques including transcriptomics, metagenomics, pangenomics, single cell omics etc. Numerous genome editing techniques including CRISPR Cas technology and their applications in crop improvement had been discussed.
    MeSH term(s) Genomics ; Gene Expression Profiling ; Phenotype ; Polymorphism, Single Nucleotide
    Language English
    Publishing date 2024-02-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2473077-4
    ISSN 1876-1631 ; 1876-1623
    ISSN (online) 1876-1631
    ISSN 1876-1623
    DOI 10.1016/bs.apcsb.2023.11.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Mitral regurgitation secondary to kissing aortic valve vegetation.

    Singh, Gurbhej / Singh, Vikram Pal / Gupta, Rajiv

    Indian journal of thoracic and cardiovascular surgery

    2023  Volume 39, Issue 4, Page(s) 423–424

    Abstract: Infective endocarditis is associated with acute heart failure if the valve involvement leads to significant alteration in the hemodynamics. Vegetation in infective endocarditis invades the tissue causing disruption of the anatomical integrity of the ... ...

    Abstract Infective endocarditis is associated with acute heart failure if the valve involvement leads to significant alteration in the hemodynamics. Vegetation in infective endocarditis invades the tissue causing disruption of the anatomical integrity of the valve structure. Heart failure in infective endocarditis is associated with high morbidity and mortality despite advances in surgical and medical therapies. Aortic valve vegetation may cause involvement of mitral valve through different mechanisms. Here, we present a case of infective endocarditis with vegetation on the aortic valve causing perforation of anterior mitral leaflet leading to severe mitral regurgitation.
    Supplementary information: The online version contains supplementary material available at 10.1007/s12055-023-01486-8.
    Language English
    Publishing date 2023-02-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164386-6
    ISSN 0973-7723 ; 0970-9134
    ISSN (online) 0973-7723
    ISSN 0970-9134
    DOI 10.1007/s12055-023-01486-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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