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  1. Article: Upper Airway Complications in COVID-19: A Case Series.

    Shrestha, Sushmita / Shin, Yong / Sostin, Oleg V / Pinkhasova, Polina / Chronakos, John

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37163

    Abstract: Prolonged intubation is associated with several complications leading to upper airway obstruction, including tracheal stenosis and tracheomalacia. Tracheostomy may potentially decrease the risk of tracheal injury in patients with upper airway obstruction. ...

    Abstract Prolonged intubation is associated with several complications leading to upper airway obstruction, including tracheal stenosis and tracheomalacia. Tracheostomy may potentially decrease the risk of tracheal injury in patients with upper airway obstruction. The ideal timing to perform tracheostomy remains controversial. Prolonged intubations were particularly common during the initial phase of the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to present a series of five cases of upper airway complications in patients who underwent mechanical ventilation in the setting of COVID-19 and discuss their clinical aspects, risk factors, and therapeutic strategies.
    Language English
    Publishing date 2023-04-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Pilot Study Of Aspirin Resistance In Obstructive Sleep Apnea Patients.

    Scinico, Maria / Sostin, Oleg V / Agarwal, Rakhee / Kapoor, Amber D / Petrini, Joann R / Mendez, Jose L

    Clinical and investigative medicine. Medecine clinique et experimentale

    2021  Volume 44, Issue 3, Page(s) E55–63

    MeSH term(s) Aspirin ; Humans ; Pilot Projects ; Sleep Apnea, Obstructive/drug therapy
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2021-10-03
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 434004-8
    ISSN 1488-2353 ; 0147-958X
    ISSN (online) 1488-2353
    ISSN 0147-958X
    DOI 10.25011/cim.v44i3.36708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1389: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 345: Show issues

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  3. Article ; Online: A matched cohort study of convalescent plasma therapy for COVID-19.

    Sostin, Oleg V / Rajapakse, Pramuditha / Cruser, Brigid / Wakefield, Dorothy / Cruser, Daniel / Petrini, Joann

    Journal of clinical apheresis

    2021  Volume 36, Issue 4, Page(s) 523–532

    Abstract: Introduction: COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a public health crisis. Prior studies demonstrated successful use of convalescent plasma therapy for treatment of other viral illnesses. Our primary ... ...

    Abstract Introduction: COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a public health crisis. Prior studies demonstrated successful use of convalescent plasma therapy for treatment of other viral illnesses. Our primary objective was to evaluate treatment efficacy of convalescent plasma in patients with COVID-19.
    Materials and methods: In this retrospective matched cohort study, we enrolled recipients of convalescent plasma collected from donors recovered from laboratory-confirmed SARS-CoV-2 infection under the single patient eIND process. We individually matched 35 cases with 61 controls based on age, gender, supplemental oxygen requirements, and C-reactive protein level at the time of hospital admission. We compared the outcomes of in-hospital mortality and hospital length of stay between the groups.
    Results: In-hospital mortality was 20% among the cases and 24.6% among the controls (P = .61). A multivariable logistic regression model that included age, gender, duration of symptoms, need for mechanical ventilation, and pharmacologic interventions revealed no significant difference in mortality by study group (P = .71). The median length of stay was significantly greater among convalescent plasma recipients compared with controls, 10 (IQR, 6-17) vs 7 (IQR, 4-11) days, P < .01. The difference was not significant after controlling for covariates (P > .1).
    Conclusions: We did not find convalescent plasma reduced in-hospital mortality in our sample, nor did it reduce length of stay. Further investigation is warranted to determine the efficacy of this treatment in patients with COVID-19, particularly early in the disease process.
    MeSH term(s) Adult ; Aged ; C-Reactive Protein/analysis ; COVID-19/blood ; COVID-19/therapy ; Female ; Hospital Mortality ; Humans ; Immunization, Passive/adverse effects ; Length of Stay ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 ; Transfusion Reaction/etiology ; COVID-19 Serotherapy
    Chemical Substances C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2021-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604912-6
    ISSN 1098-1101 ; 0733-2459
    ISSN (online) 1098-1101
    ISSN 0733-2459
    DOI 10.1002/jca.21888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1831: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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