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  1. Article ; Online: DMMG: Dual Min-Max Games for Self-Supervised Skeleton-Based Action Recognition.

    Guan, Shannan / Yu, Xin / Huang, Wei / Fang, Gengfa / Lu, Haiyan

    IEEE transactions on image processing : a publication of the IEEE Signal Processing Society

    2023  Volume 33, Page(s) 395–407

    Abstract: In this work, we propose a new Dual Min-Max Games (DMMG) based self-supervised skeleton action ... of a viewpoint variation min-max game and an edge perturbation min-max game. These two min-max games adopt ... respectively. Our viewpoint variation min-max game focuses on constructing various hard contrastive pairs ...

    Abstract In this work, we propose a new Dual Min-Max Games (DMMG) based self-supervised skeleton action recognition method by augmenting unlabeled data in a contrastive learning framework. Our DMMG consists of a viewpoint variation min-max game and an edge perturbation min-max game. These two min-max games adopt an adversarial paradigm to perform data augmentation on the skeleton sequences and graph-structured body joints, respectively. Our viewpoint variation min-max game focuses on constructing various hard contrastive pairs by generating skeleton sequences from various viewpoints. These hard contrastive pairs help our model learn representative action features, thus facilitating model transfer to downstream tasks. Moreover, our edge perturbation min-max game specializes in building diverse hard contrastive samples through perturbing connectivity strength among graph-based body joints. The connectivity-strength varying contrastive pairs enable the model to capture minimal sufficient information of different actions, such as representative gestures for an action while preventing the model from overfitting. By fully exploiting the proposed DMMG, we can generate sufficient challenging contrastive pairs and thus achieve discriminative action feature representations from unlabeled skeleton data in a self-supervised manner. Extensive experiments demonstrate that our method achieves superior results under various evaluation protocols on widely-used NTU-RGB+D, NTU120-RGB+D and PKU-MMD datasets.
    Language English
    Publishing date 2023-12-27
    Publishing country United States
    Document type Journal Article
    ISSN 1941-0042
    ISSN (online) 1941-0042
    DOI 10.1109/TIP.2023.3338410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: LABIN: Balanced Min Cut for Large-Scale Data.

    Chen, Xiaojun / Chen, Renjie / Wu, Qingyao / Fang, Yixiang / Nie, Feiping / Huang, Joshua Zhexue

    IEEE transactions on neural networks and learning systems

    2019  Volume 31, Issue 3, Page(s) 725–736

    Abstract: ... we propose a novel spectral clustering method for large-scale data, namely, large-scale balanced min cut ... LABIN). A new model is proposed to extend the self-balanced min-cut (SBMC) model with the anchor-based ...

    Abstract Although many spectral clustering algorithms have been proposed during the past decades, they are not scalable to large-scale data due to their high computational complexities. In this paper, we propose a novel spectral clustering method for large-scale data, namely, large-scale balanced min cut (LABIN). A new model is proposed to extend the self-balanced min-cut (SBMC) model with the anchor-based strategy and a fast spectral rotation with linear time complexity is proposed to solve the new model. Extensive experimental results show the superior performance of our proposed method in comparison with the state-of-the-art methods including SBMC.
    Language English
    Publishing date 2019-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 2162-2388
    ISSN (online) 2162-2388
    DOI 10.1109/TNNLS.2019.2909425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effectiveness and safety of direct oral anticoagulants in patients with venous thromboembolism and creatinine clearance < 30 mL/min.

    Cline, Lauren / Generoso, Erika Marie G / D'Apice, Nicholas / Dellinger, Sara K / Tovey, Amber / Clark, Nathan P / Nui, Fang / Hui, Rita / Hale, Stephanie A / Ramsey, Tanya / Pontoppidan, Kimi / Ekmekdjian, Hasmig / Fink, Kristen / Witt, Daniel M / Crowther, Mark A / Delate, Thomas

    Journal of thrombosis and thrombolysis

    2022  Volume 55, Issue 2, Page(s) 355–364

    Abstract: ... for the treatment of venous thromboembolism (VTE) among patients with a creatinine clearance (CrCl) < 30 mL/min ... This observational, cohort study included patients with VTE and CrCl < 30 mL/min who were newly initiated on a DOAC ... with VTE and CrCl < 30 mL/min. ...

    Abstract The few studies that compared direct oral anticoagulants (DOAC) vs. warfarin in the setting of advanced renal insufficiency have focused on patients with atrial fibrillation. The purpose of this observational, matched, cohort study of patients was to assess the effectiveness and safety of DOAC vs. warfarin for the treatment of venous thromboembolism (VTE) among patients with a creatinine clearance (CrCl) < 30 mL/min. This observational, cohort study included patients with VTE and CrCl < 30 mL/min who were newly initiated on a DOAC or warfarin between January 1, 2016 and December 31, 2020. DOAC patients were matched up to 1:2 to warfarin patients. Primary outcome was a composite of recurrent VTE, clinically-relevant bleeding, ischemic stroke, and all-cause mortality. Adjusted conditional, multivariate Cox proportional hazards modeling was used to assess outcomes. 626 DOAC patients were matched to 1071 warfarin patients. DOAC patients had a higher mean age, higher mean baseline CrCl, and were less likely to have been receiving dialysis. There was no statistically significant difference in the composite outcome between groups (adjusted hazard ratio [aHR] 1.13, 95% confidence interval [CI] 0.87-1.47) or in the individual components of the composite (all HR 95% CI crossed 1.00). Identification of statistically non-significant rates of bleeding and thromboembolic outcomes suggest that the use of DOAC or warfarin is reasonable in patients with VTE and CrCl < 30 mL/min.
    MeSH term(s) Humans ; Warfarin/adverse effects ; Anticoagulants/adverse effects ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/chemically induced ; Creatinine ; Cohort Studies ; Hemorrhage/chemically induced ; Hemorrhage/drug therapy ; Atrial Fibrillation/drug therapy ; Administration, Oral ; Retrospective Studies
    Chemical Substances Warfarin (5Q7ZVV76EI) ; Anticoagulants ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2022-12-23
    Publishing country Netherlands
    Document type Observational Study ; Journal Article
    ZDB-ID 1230645-9
    ISSN 1573-742X ; 0929-5305
    ISSN (online) 1573-742X
    ISSN 0929-5305
    DOI 10.1007/s11239-022-02758-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Reproductive Dynamics of Three Important Clupeiform Food Fishes in the Min River Estuary and Its Adjacent Nearshore Waters, China

    Xu, Qing / Jiang, Yan / Fang, Lü‐ping / Liu, Min / Jiang, Xiao‐bin

    Marine and coastal fisheries. 2021 Dec., v. 13, no. 6

    2021  

    Abstract: ... studied in the largest estuary of Fujian Province, China: the Min River estuary and its adjacent nearshore ... located for the first time: in the Min River estuary for Gray’s Grenadier Anchovy, mainly in the adjacent ... reaches of the Min River and extending to the estuary for Chinese Gizzard Shad. As important food fishes ...

    Abstract Reproductive dynamics of three important clupeiform food fishes (Gray’s Grenadier Anchovy Coilia grayii, Osbeck’s Grenadier Anchovy Coilia mystus, and Chinese Gizzard Shad Clupanodon thrissa) were studied in the largest estuary of Fujian Province, China: the Min River estuary and its adjacent nearshore waters. Samples were collected from May 2017 through July 2020 using trammel nets and trawlers. Females were observed to be significantly larger than males for Gray’s and Osbeck’s grenadier anchovies but not for Chinese Gizzard Shad. The overall sex ratios of all three species showed a significant female bias. Gonad histology was applied to determine spawning season, peak spawning season, and length at 50% maturity for females and males. The spawning season of females lasted from April to September (peak spawning season in April–July) for Gray’s Grenadier Anchovy, from March to September (peak in March–June) for Osbeck’s Grenadier Anchovy, and from April to July (peak in May–July) for Chinese Gizzard Shad. Spawning seasons of males were similar to those of females. The estimated SLs at 50% maturity for females and males, respectively, were 11.3 and 9.4 cm for Gray’s Grenadier Anchovy, 12.7 and 10.4 cm for Osbeck’s Grenadier Anchovy, and 12.7 and 11.6 cm for Chinese Gizzard Shad. The spawning grounds for these species were located for the first time: in the Min River estuary for Gray’s Grenadier Anchovy, mainly in the adjacent nearshore waters and extending to the estuary for Osbeck’s Grenadier Anchovy, and mainly in the lower reaches of the Min River and extending to the estuary for Chinese Gizzard Shad. As important food fishes in the region, stocks of these three species have shown certain degrees of overexploitation; therefore, stock assessments and management plans are necessary to achieve their sustainable fisheries.
    Keywords Coilia mystus ; Dorosoma cepedianum ; anchovies ; coastal water ; estuaries ; females ; histology ; rivers ; China
    Language English
    Dates of publication 2021-12
    Size p. 679-692.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2483227-3
    ISSN 1942-5120
    ISSN 1942-5120
    DOI 10.1002/mcf2.10186
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Min-Entropy Latent Model for Weakly Supervised Object Detection.

    Wan, Fang / Wei, Pengxu / Han, Zhenjun / Jiao, Jianbin / Ye, Qixiang

    IEEE transactions on pattern analysis and machine intelligence

    2019  Volume 41, Issue 10, Page(s) 2395–2409

    Abstract: ... and ambiguity to detectors. In this paper, a min-entropy latent model (MELM) is proposed for weakly ... supervised object detection. Min-entropy serves as a model to learn object locations and a metric to measure ...

    Abstract Weakly supervised object detection is a challenging task when provided with image category supervision but required to learn, at the same time, object locations and object detectors. The inconsistency between the weak supervision and learning objectives introduces significant randomness to object locations and ambiguity to detectors. In this paper, a min-entropy latent model (MELM) is proposed for weakly supervised object detection. Min-entropy serves as a model to learn object locations and a metric to measure the randomness of object localization during learning. It aims to principally reduce the variance of learned instances and alleviate the ambiguity of detectors. MELM is decomposed into three components including proposal clique partition, object clique discovery, and object localization. MELM is optimized with a recurrent learning algorithm, which leverages continuation optimization to solve the challenging non-convexity problem. Experiments demonstrate that MELM significantly improves the performance of weakly supervised object detection, weakly supervised object localization, and image classification, against the state-of-the-art approaches.
    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Journal Article
    ISSN 1939-3539
    ISSN (online) 1939-3539
    DOI 10.1109/TPAMI.2019.2898858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Determination of Step Frequency in 3-min Incremental Step-in-Place Tests for Predicting Maximal Oxygen Uptake from Heart Rate Response in Taiwanese Adults.

    Li, Fang / Chang, Chun-Hao / Ho, Chia-An / Wu, Cheng-You / Yeh, Hung-Chih / Chan, Yuan-Shuo / Cheng, Jia-Yu / ChangChien, Wen-Sheng / Ho, Chin-Shan

    International journal of environmental research and public health

    2022  Volume 19, Issue 1

    Abstract: The maximal oxygen uptake ( ... ...

    Abstract The maximal oxygen uptake (VO
    MeSH term(s) Adult ; Cardiorespiratory Fitness ; Cross-Sectional Studies ; Exercise Test ; Heart Rate ; Humans ; Oxygen ; Oxygen Consumption
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2022-01-05
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19010563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Microfluidic Immunoassays for Sensitive and Simultaneous Detection of IgG/IgM/Antigen of SARS-CoV-2 within 15 min.

    Lin, Qiuyuan / Wen, Donghua / Wu, Jing / Liu, Liling / Wu, Wenjuan / Fang, Xueen / Kong, Jilie

    Analytical chemistry

    2020  Volume 92, Issue 14, Page(s) 9454–9458

    Abstract: ... min), multiple, and on-site detection of IgG/IgM/Antigen of SARS-CoV-2 simultaneously. This integrated ...

    Abstract The outbreak of SARS-CoV-2 is posing serious global public health problems. Facing the emergence of this pandemic, we established a portable microfluidic immunoassay system for easy-to-use, sensitive, rapid (<15 min), multiple, and on-site detection of IgG/IgM/Antigen of SARS-CoV-2 simultaneously. This integrated method was successfully applied for detecting SARS-CoV-2 IgM and IgG antibodies in clinical human serum as well as SARS-CoV-2 antigen in pharyngeal swabs from 26 patients with COVID-19 infection and 28 uninfected people. The assay demonstrated high sensitivity and specificity, which is promising for the diagnosis and monitoring as well as control of SARS-CoV-2 worldwide.
    MeSH term(s) Antibodies, Viral/analysis ; Betacoronavirus/immunology ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunoassay/methods ; Immunoglobulin G/analysis ; Immunoglobulin M/analysis ; Microfluidic Analytical Techniques/methods ; Pandemics ; Pharynx/chemistry ; Pharynx/immunology ; Pneumonia, Viral/diagnosis ; SARS-CoV-2 ; Sensitivity and Specificity
    Chemical Substances Antibodies, Viral ; Immunoglobulin G ; Immunoglobulin M
    Keywords covid19
    Language English
    Publishing date 2020-07-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.0c01635
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: An improved online learning algorithm for general fuzzy min-max neural network

    Khuat, Thanh Tung / Chen, Fang / Gabrys, Bogdan

    2020  

    Abstract: ... fuzzy min-max neural network (GFMM) to tackle existing issues concerning expansion and contraction steps ... in the classification accuracy and stability of the proposed method compared to the original version and other fuzzy min ...

    Abstract This paper proposes an improved version of the current online learning algorithm for a general fuzzy min-max neural network (GFMM) to tackle existing issues concerning expansion and contraction steps as well as the way of dealing with unseen data located on decision boundaries. These drawbacks lower its classification performance, so an improved algorithm is proposed in this study to address the above limitations. The proposed approach does not use the contraction process for overlapping hyperboxes, which is more likely to increase the error rate as shown in the literature. The empirical results indicated the improvement in the classification accuracy and stability of the proposed method compared to the original version and other fuzzy min-max classifiers. In order to reduce the sensitivity to the training samples presentation order of this new on-line learning algorithm, a simple ensemble method is also proposed.

    Comment: 9 pages, 8 tables, 6 figures
    Keywords Computer Science - Machine Learning ; Statistics - Machine Learning ; I.2.1 ; I.2.6 ; I.2.m ; I.5.0 ; I.5.1 ; I.5.2 ; I.5.3 ; I.5.4
    Subject code 006
    Publishing date 2020-01-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Microfluidic-CFPA Chip for the Point-of-Care Detection of African Swine Fever Virus with a Median Time to Threshold in about 10 min.

    Ye, Xin / Li, Lin / Li, Jian / Wu, Xiaodong / Fang, Xueen / Kong, Jilie

    ACS sensors

    2019  Volume 4, Issue 11, Page(s) 3066–3071

    Abstract: ... for the diagnosis of African swine fever virus, with a median time to threshold of 10.8 min. This novel integrated ...

    Abstract The outbreak of African swine fever has brought serious public safety problems to the world, and there is a need for reliable diagnostic tools to prevent and control the epidemic. Here, we successfully established a portable microfluidic-circular fluorescent probe-mediated isothermal nucleic acid amplification (CFPA) system for the rapid, high-throughput, accurate, and sensitive detection of African swine fever virus at point-of-care settings. This detection system has a detection limit of 10 copies/μL, good stability (C.V. < 5%), and 92.73% sensitivity, and 100% specificity when tested on 220 pig samples collected for the diagnosis of African swine fever virus, with a median time to threshold of 10.8 min. This novel integrated diagnostic tool is urgently needed and has promising applications for the monitoring and control of African swine fever epidemics worldwide and, in particular, the serious outbreak in China.
    MeSH term(s) African Swine Fever Virus/isolation & purification ; Biosensing Techniques ; Fluorescent Dyes/chemistry ; Lab-On-A-Chip Devices ; Nucleic Acid Amplification Techniques ; Point-of-Care Systems ; Time Factors
    Chemical Substances Fluorescent Dyes
    Language English
    Publishing date 2019-10-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.9b01731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oxygen desaturation during the 6-min walk test as a risk for osteoporosis in non-cystic fibrosis bronchiectasis.

    Huang, Hung-Yu / Sheng, Te-Fang / Lin, Chang-Wei / Wang, Ting-Wen / Lo, Chun-Yu / Chung, Fu-Tsai / Yang, Lan-Yan / Pan, Yu-Bin / Wang, Chun-Hua

    BMC pulmonary medicine

    2019  Volume 19, Issue 1, Page(s) 28

    Abstract: ... patients. We determined whether desaturation during 6-min walk test (6MWT) can be a predictor ...

    Abstract Background: Osteoporosis is a common comorbidity in non-cystic fibrosis (non-CF) bronchiectasis patients. We determined whether desaturation during 6-min walk test (6MWT) can be a predictor for osteoporosis risk.
    Methods: This was a retrospective cross-sectional study. Sixty-six non-CF bronchiectasis patients were enrolled. Lung function, walking distance, the lowest oxygen saturation (SpO
    Results: Osteoporosis was evident in more desaturators (82%) than non-desaturators (43%, p < 0.01). BMD at the level of the femoral neck was significantly lower in desaturators than in non-desaturators (- 3.6 ± 1.1 vs. - 2.4 ± 0.9, p < 0.01). BMD was correlated positively with the lowest SpO
    Conclusions: Exertional desaturation during the 6MWT was a significant predictive factor for osteoporosis in Asian non-CF bronchiectasis patients. The 6MWT may be useful in identifying the osteoporotic phenotype of non-CF bronchiectasis and increasing clinician awareness to promote early intervention.
    MeSH term(s) Aged ; Bone Density ; Bronchiectasis/complications ; Bronchiectasis/physiopathology ; Comorbidity ; Cross-Sectional Studies ; Exercise Tolerance ; Female ; Forced Expiratory Volume ; Humans ; Linear Models ; Male ; Middle Aged ; Multivariate Analysis ; Osteoporosis/complications ; Osteoporosis/diagnosis ; Oxygen/blood ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors ; Taiwan ; Tomography, X-Ray Computed ; Walk Test
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2019-02-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-019-0794-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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