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  1. Article ; Online: Electrocatalytic oxidation of biomass derived molecules.

    Fan, Yun / Zou, Yuqin / Wang, Shuangyin

    Science bulletin

    2023  Volume 68, Issue 22, Page(s) 2695–2699

    MeSH term(s) Biomass ; Oxidation-Reduction ; Electrodes
    Language English
    Publishing date 2023-09-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2816140-3
    ISSN 2095-9281 ; 2095-9273
    ISSN (online) 2095-9281
    ISSN 2095-9273
    DOI 10.1016/j.scib.2023.09.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Preparation of

    Wang, Yuqin / Fan, Pingping / Zhang, Shanyu / Yan, Shuanghong / Huang, Shuo

    Biophysics reports

    2023  Volume 7, Issue 5, Page(s) 355–364

    Abstract: Mycobacterium ... ...

    Abstract Mycobacterium smegmatis
    Language English
    Publishing date 2023-05-22
    Publishing country China
    Document type Journal Article
    ISSN 2364-3420
    ISSN (online) 2364-3420
    DOI 10.52601/bpr.2021.210016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Purification and Identification of Peptides from

    Tang, Yufang / Liang, Fan / Yan, Yue / Zeng, Yanlin / Li, Yuqin / Zhou, Rong

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 8, Page(s) 4170–4183

    Abstract: Antioxidant peptides were purified ... ...

    Abstract Antioxidant peptides were purified from
    MeSH term(s) Humans ; Antioxidants/chemistry ; Hydrogen Peroxide/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Hydrocharitaceae/metabolism ; Hep G2 Cells ; Tandem Mass Spectrometry ; Molecular Docking Simulation ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Peptides/chemistry ; Oxidative Stress
    Chemical Substances Antioxidants ; Hydrogen Peroxide (BBX060AN9V) ; Kelch-Like ECH-Associated Protein 1 ; NF-E2-Related Factor 2 ; Peptides
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c09917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Nanopore analysis of salvianolic acids in herbal medicines.

    Fan, Pingping / Zhang, Shanyu / Wang, Yuqin / Li, Tian / Zhang, Hanhan / Zhang, Panke / Huang, Shuo

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1970

    Abstract: Natural herbs, which contain pharmacologically active compounds, have been used historically as medicines. Conventionally, the analysis of chemical components in herbal medicines requires time-consuming sample separation and state-of-the-art analytical ... ...

    Abstract Natural herbs, which contain pharmacologically active compounds, have been used historically as medicines. Conventionally, the analysis of chemical components in herbal medicines requires time-consuming sample separation and state-of-the-art analytical instruments. Nanopore, a versatile single molecule sensor, might be suitable to identify bioactive compounds in natural herbs. Here, a phenylboronic acid appended Mycobacterium smegmatis porin A (MspA) nanopore is used as a sensor for herbal medicines. A variety of bioactive compounds based on salvianolic acids, including caffeic acid, protocatechuic acid, protocatechualdehyde, salvianic acid A, rosmarinic acid, lithospermic acid, salvianolic acid A and salvianolic acid B are identified. Using a custom machine learning algorithm, analyte identification is performed with an accuracy of 99.0%. This sensing principle is further used with natural herbs such as Salvia miltiorrhiza, Rosemary and Prunella vulgaris. No complex sample separation or purification is required and the sensing device is highly portable.
    MeSH term(s) Nanopores ; Plants, Medicinal ; Algorithms ; Plant Extracts ; Alkenes ; Polyphenols
    Chemical Substances salvianolic acid ; Plant Extracts ; Alkenes ; Polyphenols
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-45543-1
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  5. Article ; Online: Synthesis of 1,7-Fused Indolines Tethered with Spiroindolinone Based on C-H Activation Strategy with Air as a Sustainable Oxidant.

    He, Xing / Liu, Kangli / Yan, Shengnan / Wang, Yue / Jiang, Yuqin / Zhang, Xinying / Fan, Xuesen

    The Journal of organic chemistry

    2024  Volume 89, Issue 3, Page(s) 1880–1897

    Abstract: Herein, we present an efficient synthesis of 1,7-fused indolines tethered with a spiroindolinonyl moiety through the cascade reaction of indolin-1-yl(aryl)methanimines with diazo oxindoles. To the best of our knowledge, this is the first example in which ...

    Abstract Herein, we present an efficient synthesis of 1,7-fused indolines tethered with a spiroindolinonyl moiety through the cascade reaction of indolin-1-yl(aryl)methanimines with diazo oxindoles. To the best of our knowledge, this is the first example in which 1,7-fused indoline skeleton was constructed along with the simultaneous introduction of a spiro element initiated by the C-H bond activation of indoline. In forming the title product, the indoline substrate and the diazo coupling partner demonstrated an unprecedented reaction pattern in which the latter acts as a C1 synthon to participate in the construction of the spirocyclic scaffold through the reductive elimination of a key seven-membered Ru(II) species by using air as an effective and sustainable oxidant to regenerate the active catalyst. Moreover, studies on the cytotoxicity of selected products against several human cancer cell lines demonstrated their potential as lead compounds for the development of anticancer drugs. With notable features such as simple and economical substrates, pharmaceutically valuable products with sophisticated spirocyclic skeleton, mild reaction conditions, cost-free and sustainable oxidants, high efficiency, excellent compatibility with diverse functional groups, and scalability, this method is expected to find wide applications in related areas.
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c02630
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  6. Article: Endocrine disruptors affect the expression of estrogen receptor genes and proteins in the white cloud mountain minnow

    Ke, Chen / Meilin, Chen / Guangzhi, Ma / Yuqin, Fan / Lin, Liu / Weiting, Chen

    Frontiers in physiology

    2022  Volume 13, Page(s) 1020840

    Abstract: The endocrine disruptor chemicals (EDCs) are ubiquitous in the environment, and it has raised wide public concern because of the dangers of EDCs for living organisms and the environment. In order to comparatively study the effects of EDCs [17-α- ... ...

    Abstract The endocrine disruptor chemicals (EDCs) are ubiquitous in the environment, and it has raised wide public concern because of the dangers of EDCs for living organisms and the environment. In order to comparatively study the effects of EDCs [17-α-ethinylestradiol (EE
    Language English
    Publishing date 2022-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.1020840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Latent class analysis of psychological resilience and influencing factors in patients with rheumatoid arthritis: a cross-sectional survey.

    Zhou, Jian / Gan, Yuqin / Fan, Xinxin / Qi, Hong / Cao, Yuqiong / Luo, Zongting

    Clinical rheumatology

    2024  

    Abstract: Objectives: To investigate the latent class of psychological resilience in patients with rheumatoid arthritis (RA) and examine the factors influencing various latent types.: Methods: A cross-sectional survey design was used in this study. A total of ... ...

    Abstract Objectives: To investigate the latent class of psychological resilience in patients with rheumatoid arthritis (RA) and examine the factors influencing various latent types.
    Methods: A cross-sectional survey design was used in this study. A total of 480 patients with RA were enrolled from two tertiary care institutions in Chengdu, Sichuan Province, between May and November 2023, using the convenience sample approach. The General Information Questionnaire, CD-RISC-10, SSRS, ASES-8, and BRAF-MDQ were used to analyze the latent classes of psychological resilience in the respondents, and the factors influencing the latent classes were explored using one-way analysis of variance, analysis of variance, and multi-categorical logistic regression analysis.
    Results: Overall, 423 valid questionnaires were returned, indicating an 88.13% effective return rate. A latent class analysis revealed that RA patients were divided into three classes of psychological resilience: low-level (20.3%), moderate-level (31.0%), and high-level (48.7%) psychological resilience. A multi-categorical logistic regression analysis found that social support, self-efficacy, weariness, age, work status, and somatic pain all significantly influenced psychological resilience in RA patients.
    Conclusion: Three classes of RA patients' psychological resilience were identified by this study, and these classes were strongly correlated with individual treatment components. It is crucial to take into account the psychological resiliency of female RA patients who do not have a job. In order to improve psychological resilience, healthcare staff should first increase their comprehension of treat-to-target. Furthermore, people with RA may become more psychologically resilient if they receive more social support. Key Points • Preliminary research found that psychological resilience in RA patients was associated with three latent classes. • In RA patients, psychological resilience was significantly influenced by self-efficacy, fatigue, age, work status, physical pain, and social support. • The fundamental goal of bolstering RA patients' psychological resilience is to reaffirm their place in the treatment process, for example, by improving patient compliance and achieving treat-to-target earlier.
    Language English
    Publishing date 2024-04-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-024-06959-8
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  8. Article ; Online: Efficacy of prophylactic laser retinopexy in acute retinal necrosis: A systematic review and meta-analysis.

    Fan, Shipei / Lin, Dan / Wu, Ronghan / Wang, Yuqin

    International ophthalmology

    2022  Volume 42, Issue 5, Page(s) 1651–1660

    Abstract: Purpose: We performed a systematic review and meta-analysis to assess the role of prophylactic laser retinopexy in preventing rhegmatogenous retinal detachment (RRD) in acute retinal necrosis (ARN).: Methods: Pubmed, Embase and Cochrane databases ... ...

    Abstract Purpose: We performed a systematic review and meta-analysis to assess the role of prophylactic laser retinopexy in preventing rhegmatogenous retinal detachment (RRD) in acute retinal necrosis (ARN).
    Methods: Pubmed, Embase and Cochrane databases were searched for eligible studies from inception to July 2020. Comprehensive clinical demographics were extracted from each study by two independent investigators. A random effects model was selected to analyze the OR of RRD risk and visual outcome with 95%CI. Subsequent subgroup and sensitivity analysis were conducted to evaluate the source of heterogeneity.
    Results: A total of eight studies and 247 eyes (111 prophylactic laser retinopexy eyes and 136 eyes receiving antiviral treatment) were included in this analysis. There was moderate statistical heterogeneity across all studies. When compared with routine antiviral treatment alone, RRD risk decreased in patients receiving prophylactic laser retinopexy, however, this was not statistically significant (P = 0.09, OR = 0.42, 95%CI: 0.15-1.15). There was significant improvement in BCVA during the follow-up period in the prophylactic laser retinopexy subgroup (P = 0.01, WMD = - 0.98, 95%CI: - 1.74, - 0.22).
    Conclusion: Based on current analysis, our results did not support convincing evidence of prophylactic laser in preventing RRD. Future studies featuring high-quality, multicenter trials will be required to correct baseline characteristics.
    Trial registration: This meta-analysis has been retrospectively registered in Prospero (registration number: CRD42020201008).
    MeSH term(s) Antiviral Agents ; Humans ; Lasers ; Retina ; Retinal Detachment/etiology ; Retinal Detachment/surgery ; Retinal Necrosis Syndrome, Acute/diagnosis ; Retinal Necrosis Syndrome, Acute/etiology ; Retinal Necrosis Syndrome, Acute/surgery ; Retrospective Studies ; Visual Acuity ; Vitrectomy/methods
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2022-03-21
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-021-02131-2
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  9. Article: Comparative Study of the Gut Microbiota Community between the Farmed and Wild

    Liu, Xiongjun / Fan, Yuqin / Mo, Tao / Chen, Qingxiu / Chen, Weiting

    Metabolites

    2022  Volume 12, Issue 12

    Abstract: Cultivated and wild fish of the same species may exhibit different characteristics, such as in their flavor, growth and development. In some wild fish species, reproductive functions may even be retarded when wild individuals are moved into cultivated ... ...

    Abstract Cultivated and wild fish of the same species may exhibit different characteristics, such as in their flavor, growth and development. In some wild fish species, reproductive functions may even be retarded when wild individuals are moved into cultivated conditions. The gut microbiota may be one of the reasons for these phenomena as they have been reported to play an important role in host growth and development, as well as in normal reproductive functioning. Here, we used
    Language English
    Publishing date 2022-11-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662251-8
    ISSN 2218-1989
    ISSN 2218-1989
    DOI 10.3390/metabo12121193
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  10. Article ; Online: Rhizopus oryzae fermentation wastewater nutrient removal coupling protein fodder production by employing Chlorella pyrenoidosa.

    Bai, Yanan / Li, Yuqin / Tang, Yufang / Zhou, Rong / Fan, Yiwen

    Bioresource technology

    2022  Volume 362, Page(s) 127858

    Abstract: The scenario was to investigate feasibilities of employing Chlorella pyrenoidosa for Rhizopus oryzae fermentation wastewater nutrient removal coupling protein fodder production. Results stated that TN, TP, ... ...

    Abstract The scenario was to investigate feasibilities of employing Chlorella pyrenoidosa for Rhizopus oryzae fermentation wastewater nutrient removal coupling protein fodder production. Results stated that TN, TP, NH
    MeSH term(s) Amino Acids, Essential ; Animal Feed ; Biomass ; Chlorella/metabolism ; Fermentation ; Microalgae/metabolism ; Nutrients ; Rhizopus/metabolism ; Rhizopus oryzae ; Waste Water/chemistry
    Chemical Substances Amino Acids, Essential ; Waste Water
    Language English
    Publishing date 2022-08-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2022.127858
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