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Article ; Online: Benefits of Tai Chi Quan on neurodegenerative diseases: A systematic review.

Wang, Rui / Zhou, Hao / Wang, Yu-Chen / Chang, Xiao-Long / Wang, Xue-Qiang

2022 Volume 82, Page(s) 101741

Abstract: ... process. Tai Chi Quan (TCQ) has positive benefits for brain health and chronic diseases. The aim ...

Abstract	Background: Neurodegenerative diseases have become an important concern with the accelerated aging process. Tai Chi Quan (TCQ) has positive benefits for brain health and chronic diseases. The aim of this study was to summarize the protective effects of TCQ for motor function, cognition, quality of life, and mood in patients with neurodegenerative diseases. Methods: A systematic search was conducted via PubMed database and the Web of Science core collection database until August 20, 2021. The available English systematic reviews, meta-analyses, and clinical trials were included. Two reviewers completed the screening and assessment process independently. Results: A total of 28 studies on Parkinson's disease, 21 on cognitive impairment, and 9 on multiple sclerosis met the included criteria. The study found that TCQ remarkably improved general motor function and balance, and prevented falls for Parkinson's disease. TCQ significantly improved global cognitive function for cognitive impairment. TCQ was likely safe and beneficial for multiple sclerosis as result of heterogeneous outcomes and small samples. Conclusion: TCQ exercise can effectively improve the motor function, global cognitive function, and falls in patients with neurodegenerative diseases. However, the positive effects of TCQ on the quality of life and mood of patients with neurodegenerative diseases need further evidence.
MeSH term(s)	Humans ; Tai Ji ; Parkinson Disease/therapy ; Parkinson Disease/psychology ; Quality of Life ; Neurodegenerative Diseases/therapy ; Multiple Sclerosis/therapy
Language	English
Publishing date	2022-10-08
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2075672-0
ISSN	1872-9649 ; 1568-1637
ISSN (online)	1872-9649
ISSN	1568-1637
DOI	10.1016/j.arr.2022.101741
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Zs.A 5579: Show issues

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Article ; Online: Multi-omics approaches revealed the therapeutic mechanisms of Suo-Quan-Wan for treating overactive bladder in spontaneously hypertensive rats.

Sun, Zhihui / Tie, Yan / Tong, Xinyi / Cheng, Mingchang / Wu, Yushan / Xu, Pingxiang / Xue, Ming / Xu, Liping / Zhou, Xuelin

Journal of ethnopharmacology

2023 Volume 318, Issue Pt B, Page(s) 117066

Abstract: Ethnopharmacological relevance: Suo-Quan-Wan (SQW), a traditional Chinese prescription, has been ...

Abstract	Ethnopharmacological relevance: Suo-Quan-Wan (SQW), a traditional Chinese prescription, has been used for hundreds of years to alleviate overactive bladder (OAB) symptoms such as frequent and nocturnal urination. However, limited modern research on OAB therapeutic targets has hindered the use and development of SQW. Aim of the study: This study aimed to investigate the biological mechanisms and key targets of SQW on OAB in spontaneously hypertensive rats (SHR) using an integrated analysis of network pharmacology, transcriptome and metabolome. Methods: Rats were divided into five groups: model group (SHR), control group (WKY), darifenacin group, high dose (SQWH) and low dose (SQWL) group. Urodynamic parameters and histological examination were detected. Network pharmacology, transcriptome, and metabolome were used to screen for disease gene targets, differential mRNA, and differential metabolites, respectively. The biological targets and mechanisms of SQW for OAB were analyzed. Western blotting was performed to verify the proteins of key differential targets. Results: Urodynamics revealed a significant decrease in storage parameters in SHR. After SQW treatment, the inter-contraction interval, voided volume and bladder capacity increased by 2-3 times, as well as bladder compliance. Additionally, SQW improved the pathological changes in the urinary tract epithelium and the detrusor layer of the bladder in SHR. Metabolomic results showed an increase in arachidonic acid (AA) and cyclic adenosine monophosphate (cAMP) in plasma, suggesting the involvement of arachidonic acid metabolism and purine metabolism in SQW treatment. The downregulation of cytochrome P450 1B1 (CYP1B1), thromboxane-A synthase (TBXAS1), polyunsaturated fatty acid 5-lipoxygenase (ALOX5), and cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B) were confirmed through topological analysis and Venn analysis of omics data and network pharmacology. These proteins affected the metabolism of AA and cAMP, respectively, and consequently affected downstream proteins, such as transient receptor potential (TRP) cation channel proteins (e.g. TRPV1, TRPA1, and TRPM8), myosin light chain kinase (MLCK), and the phosphorylation of myosin regulatory light chain (p-MLC). Conclusion: This study initially elucidated the importance of AA and cAMP in the treatment of SQW, indicating the AA-CYP1B1/TBXAS1/ALOX5-TRPA1/TRPV1/TRPM8 and cAMP-PDE4B-MLCK-p-MLC pathways as the important pathways in SQW-treated SHR bladder in vivo.
MeSH term(s)	Rats ; Animals ; Rats, Inbred WKY ; Urinary Bladder, Overactive/drug therapy ; Rats, Inbred SHR ; Arachidonic Acid ; Multiomics ; Arachidonate 5-Lipoxygenase ; Cyclic AMP
Chemical Substances	Arachidonic Acid (27YG812J1I) ; Arachidonate 5-Lipoxygenase (EC 1.13.11.34) ; Cyclic AMP (E0399OZS9N)
Language	English
Publishing date	2023-08-20
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.117066
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Zs.A 1494: Show issues

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Article ; Online: Suo Quan Wan ameliorates bladder overactivity and regulates neurotransmission via regulating Myosin Va protein expression.

Zhang, Yao / Zhang, Jiao / Hong, Ming / Huang, Jingyi / Xu, Siyuan / Wang, Rui / Zhou, Na / Huang, Ping / Tan, Bo / Cao, Hongying

Phytomedicine : international journal of phytotherapy and phytopharmacology

2022 Volume 104, Page(s) 154265

Abstract: Background: Ancient prescriptions of Suo Quan Wan (SQW) have therapeutic effects on diabetic ...

Abstract	Background: Ancient prescriptions of Suo Quan Wan (SQW) have therapeutic effects on diabetic bladder dysfunction. However, the underlying mechanism remains unclear. Here, we hypothesized that SQW ameliorates bladder overactivity and regulates neurotransmission via regulating Myosin Va protein expression. Methods: After diabetic rats were induced by streptozotocin (65 mg/kg), the model of diabetic bladder dysfunction was established by detecting fasting blood glucose, urodynamic test, in vitro muscle strip experiments, and histological examination. One week after induction, SQW was given to observe the therapeutic effect. The expression levels of Myosin Va in control, Model, SQW L and SQW H groups were detected by RT-qPCR, RNAscope and immunofluorescence assay. The expression levels of ChAT, SP, nNOS and VIP proteins were observed by immunofluorescence assay. After knockdown and overexpression of Myosin Va, the expression changes of ChAT, SP, nNOS and VIP and the regulatory role of SQW were observed. Results: STZ-induced DM rats had significantly higher serum glucose levels and lower body weight. Compared with the diabetic rats, SQW treatment significantly improved urination function with decreased residual volume (RV), bladder compliance (BC), non-voiding contractions (NVCs), and increased voided efficiency (VE). In addition, contractile responses of muscle strips to electrical-field stimulation (EFS), carbachol (CCh), KCl were significantly lower in the SQW H and SQW L groups than those in the model group. RT-qPCR found that the expression of Myosin Va in the bladder tissue or bladder neurons in model group was significantly increased compared with the control group, and SQW treatment significantly decreased the levels of Myosin Va. In DM rats, ChAT and SP expression were significantly increased, while nNOS and VIP expression were significantly decreased, and SQW improved this phenomenon. Interestingly, SQW ameliorated the abnormal expression of ChAT, SP, nNOS and VIP caused by myosin Va knockdown, and Myosin Va overexpression results are consistent with these. Conclusions: SQW ameliorates overactive bladder and regulate neurotransmission via regulating Myosin Va mRNA and protein expression.
MeSH term(s)	Animals ; Diabetes Mellitus, Experimental/metabolism ; Muscle Contraction ; Myosins/metabolism ; Myosins/pharmacology ; Rats ; Streptozocin/pharmacology ; Synaptic Transmission ; Urinary Bladder ; Urodynamics
Chemical Substances	Streptozocin (5W494URQ81) ; Myosins (EC 3.6.4.1)
Language	English
Publishing date	2022-06-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2022.154265
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Zs.A 4115: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Suo Quan Wan ameliorates bladder overactivity and regulates neurotransmission via regulating Myosin Va protein expression

Zhang, Yao / Zhang, Jiao / Hong, Ming / Huang, Jingyi / Xu, Siyuan / Wang, Rui / Zhou, Na / Huang, Ping / Tan, Bo / Cao, Hongying

Phytomedicine. 2022 Sept., v. 104

2022

Abstract: Ancient prescriptions of Suo Quan Wan (SQW) have therapeutic effects on diabetic bladder ...

Abstract	Ancient prescriptions of Suo Quan Wan (SQW) have therapeutic effects on diabetic bladder dysfunction. However, the underlying mechanism remains unclear. Here, we hypothesized that SQW ameliorates bladder overactivity and regulates neurotransmission via regulating Myosin Va protein expression. After diabetic rats were induced by streptozotocin (65 mg/kg), the model of diabetic bladder dysfunction was established by detecting fasting blood glucose, urodynamic test, in vitro muscle strip experiments, and histological examination. One week after induction, SQW was given to observe the therapeutic effect. The expression levels of Myosin Va in control, Model, SQW L and SQW H groups were detected by RT-qPCR, RNAscope and immunofluorescence assay. The expression levels of ChAT, SP, nNOS and VIP proteins were observed by immunofluorescence assay. After knockdown and overexpression of Myosin Va, the expression changes of ChAT, SP, nNOS and VIP and the regulatory role of SQW were observed. STZ-induced DM rats had significantly higher serum glucose levels and lower body weight. Compared with the diabetic rats, SQW treatment significantly improved urination function with decreased residual volume (RV), bladder compliance (BC), non-voiding contractions (NVCs), and increased voided efficiency (VE). In addition, contractile responses of muscle strips to electrical-field stimulation (EFS), carbachol (CCh), KCl were significantly lower in the SQW H and SQW L groups than those in the model group. RT-qPCR found that the expression of Myosin Va in the bladder tissue or bladder neurons in model group was significantly increased compared with the control group, and SQW treatment significantly decreased the levels of Myosin Va. In DM rats, ChAT and SP expression were significantly increased, while nNOS and VIP expression were significantly decreased, and SQW improved this phenomenon. Interestingly, SQW ameliorated the abnormal expression of ChAT, SP, nNOS and VIP caused by myosin Va knockdown, and Myosin Va overexpression results are consistent with these. SQW ameliorates overactive bladder and regulate neurotransmission via regulating Myosin Va mRNA and protein expression.
Keywords	bladder ; blood glucose ; body weight ; carbachol ; compliance ; fluorescent antibody technique ; histology ; muscles ; myosin ; protein synthesis ; streptozotocin ; synaptic transmission ; therapeutics ; urination
Language	English
Dates of publication	2022-09
Publishing place	Elsevier GmbH
Document type	Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2022.154265
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 4115: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article: [Effect of Tai Ji Quan Training on Strength and Function of Lower Limbs in the Aged].

Zhu, Ya-qiong / Peng, Nan / Zhou, Ming

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

2016 Volume 36, Issue 1, Page(s) 49–53

Abstract: Objective: To observe the effect of Tai Ji Quan (TJQ) training on strength and function ...

Abstract	Objective: To observe the effect of Tai Ji Quan (TJQ) training on strength and function of lower limbs in the aged. Methods: Sixty senile subjects were recruited and assigned to the TJQ group and the control group (imparting health knowledge)by random digit table. Patients in the TJQ group received 24-style TJQ training for 18 months (60 min each time, 5 times per week), while those in the control group were imparted with sarcopenia related causes, pathogeneses, prevention and control measures. The maximum isometric strength of bilateral iliopsoas, quadriceps femoris, tibialis anterior muscle, hamstrings; the time for 5 sitting-up tests and Time Up and Go Test (TUGT), one-leg standing time with closed eyes test; and the score of Berg balance scale were compared between the two groups. Results: Compared with before treatment, muscle strength increased in the TJQ group with an average increased capacity (rate) as follows, bilateral iliopsoas 5.5 kg (16.9%), quadriceps femoris 5.5 kg (26.2%), and tibialis anterior muscle 8.5 kg (36.2%) (all P < 0.05). The time for TUGT and 5 sitting-up tests was shortened by 1.3 s (16.7%) and 0.9 s (14.5%) respectively in the TJQ group. The time for one-leg standing time with closed eyes test was increased by 8.4 s (left) and 9.1 s (right) respectively. The score of Berg balance scale increased by 4.3% (P < 0.05). Compared with the control group, bilateral quadriceps femoris and tibialis anterior muscle strength increased significantly (P < 0.01); the time for TUGT and 5 sitting-up tests, the time for one-leg standing time with closed eyes test, scores of Berg balance scale were all improved in the TJQ group after intervention (P < 0.05). Conclusion: TJQ training could improve strength of iliopsoas, quadriceps femoris, tibialis anterior muscle in the aged, elevate their balance and locomotor activities, and possibly prevent and treat sarcopenia.
MeSH term(s)	Exercise Therapy ; Humans ; Lower Extremity ; Muscle Strength ; Muscle, Skeletal ; Postural Balance ; Tai Ji
Language	Chinese
Publishing date	2016-01
Publishing country	China
Document type	English Abstract ; Journal Article ; Randomized Controlled Trial
ZDB-ID	1195456-5
ISSN	1003-5370
ISSN	1003-5370
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Zs.B 2863: Show issues

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Book: Yu mi zhong zi da quan

Zhou, Hongsheng

Corn : improvement, seeds production and distribution

2000

Title variant	Corn :
Author's details	Zhou Hongsheng bian zhu / Hongsheng Zhou
Keywords	Corn/Seeds. ; Corn/Breeding.
Language	Chinese
Size	2, 2, 686 p., [17] p. of plates :, ill. (some col.) ;, 21 cm.
Edition	Di 1 ban.
Publisher	Zhongguo nong ye chu ban she ; Xin hua shu dian Beijing fa xing suo fa xing
Publishing place	Beijing shi
Document type	Book
ISBN	7109066401 ; 9787109066403
Database	NAL-Catalogue (AGRICOLA)

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Book: Quan tang wen xin bian

Zhou, Shaoliang

2000

Author's details	Zhou shao liang zhu bian
Language	Chinese
Size	22 v., 29 cm
Edition	Di 1 ban
Publisher	Ji lin wen shi chu ban she
Publishing place	Chang chun
Document type	Book
Database	Former special subject collection: coastal and deep sea fishing

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Book ; Online: Physical, Chemical and Biological Processes in Energy Geoscience

Gao, Ping / Cai, Yidong / Zhou, Yingfang / Gan, Quan

2023

Keywords	Research & information: general ; taphrogenic trough ; Qianshuidi 1 well ; carboniferous strata ; pore structure ; total pore volume ; coalbed methane ; Weibei Field ; gas content ; geological control factors ; Ordos Basin ; pore size distribution ; MICP ; NMR ; pore network model ; tight sandstone ; condensate gas ; volcanic rocks ; Penyijingxi Sag ; Junggar basin ; Carboniferous ; diagenesis ; secondary pores ; organic acid dissolution ; hydrocarbon accumulation ; eastern slope of Mahu sag ; Junggar Basin ; natural gas genesis ; migration characteristics ; carbon isotopes ; light hydrocarbons ; marine shale ; open and semi-open system pyrolysis ; formation pressure ; pore structure evolution ; strike-slip fault ; active period ; Maigaiti Slope ; Tarim Basin ; CBM vertical well ; low production ; Qinshui Basin ; reconstruction potential evaluation ; coal-measure source rock ; input of terrestrial organic matter ; depositional environment ; sedimentary rate ; Jurassic system ; Kuqa Depression ; gossan ore ; ZnFeO4 ; roasting ; preparation ; matrix compressibility ; mercury intrusion porosimetry ; low-temperature nitrogen adsorption ; brittleness index ; tight sandstone gas ; reservoir ; porosity ; geological model ; seismic facies ; paleogeomorphology ; stratigraphic pattern ; seismic forward modeling ; Qinnan depression ; carbon and oxygen isotopes ; organic matter ; fluid migration ; stylolites ; carbonate rock
Language	English
Size	1 electronic resource (284 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030645975
ISBN	9783036594064 ; 303659406X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book: Zhou Xuehai yi xue quan shu

Zhou, Xuehai / Zheng, Hongxin / Li, Jinglin

(Ming Qing ming yi quan shu da cheng)

1999

Title translation	Zhou Xuehai's complete works of medicine.
Author's details	zhu bian Zheng Hongxin, Li Jinglin
Series title	Ming Qing ming yi quan shu da cheng
MeSH term(s)	Medicine, Chinese Traditional
Language	Chinese
Size	4, 3, 674 p. ;, 27 cm.
Edition	Di 1 ban.
Publisher	Zhongguo Zhong yi yao chu ban she
Publishing place	Beijing
Document type	Book
ISBN	9787801560117 ; 7801560116
Database	Catalogue of the US National Library of Medicine (NLM)

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Book: Zhongguo nong ye quan shu

Zhou, Jichang

1994

Author's details	[zhu bian Zhou Jichang]
Keywords	Agriculture ; Agriculture/Economic aspects ; Agricultural resources ; Agricultural productivity
Language	Chinese
Size	3, 2, 19, 567 p. :, ill. (some col.), maps (some col.) ;, 27 cm.
Edition	Di 1 ban.
Publisher	Zhongguo nong ye chu ban she ; Xin hua shu dian Beijing fa xing suo fa xing
Publishing place	Beijing
Document type	Book
ISBN	7109036065 ; 9787109036062
Database	NAL-Catalogue (AGRICOLA)

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