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  1. Article ; Online: Malnutrition screening tool use in a New Zealand hospital: Reliability and rates of malnutrition screening on admission.

    Diep-Pham, Huyen-Tran / Donald, Natasha / Wall, Catherine L

    Nutrition & dietetics: the journal of the Dietitians Association of Australia

    2023  Volume 80, Issue 5, Page(s) 530–537

    Abstract: Aims: This research aimed to assess the rate and reliability of routine nurse-completed malnutrition screening and report the prevalence of malnutrition risk on admission to Christchurch Hospital.: Methods: Student dietitians administered the ... ...

    Abstract Aims: This research aimed to assess the rate and reliability of routine nurse-completed malnutrition screening and report the prevalence of malnutrition risk on admission to Christchurch Hospital.
    Methods: Student dietitians administered the Malnutrition Screening Tool to patients in three speciality wards within 48 h of admission. Student dietitians' Malnutrition Screening Tool scores were compared against documented nurse-completed Malnutrition Screening Tool scores. Data were analysed using descriptive statistics, Fisher's exact test, and Cohen's kappa tests (interrater reliability ⱪ). A p-value <0.05 was considered statistically significant.
    Results: Student dietitians, using the Malnutrition Screening Tool, screened 360 (96%) of 377 eligible patients while nurses screened 332 (88%) patients. Student dietitians and nurses screened 119 patients (33%) and 63 patients (18%) respectively at risk of malnutrition. There was fair agreement (ⱪ = 0.311) in Malnutrition Screening Tool total scores between nurses and student dietitians. There was a significant difference in the proportion of patients screened at risk of malnutrition between nurses and student dietitians (p < 0.0001).
    Conclusion: Malnutrition risk remains high in acute care settings. Nurses were less likely to screen patients as at risk of malnutrition than student dietitians. Regular support and training in using Malnutrition Screening Tool may help improve the rate and reliability of routine malnutrition screening.
    MeSH term(s) Humans ; Nutrition Assessment ; Reproducibility of Results ; New Zealand/epidemiology ; Tool Use Behavior ; Malnutrition/diagnosis ; Malnutrition/epidemiology ; Hospitals
    Language English
    Publishing date 2023-08-23
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2082047-1
    ISSN 1747-0080 ; 1446-6368
    ISSN (online) 1747-0080
    ISSN 1446-6368
    DOI 10.1111/1747-0080.12838
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A multidisciplinary atrial fibrillation clinic.

    Tran, Huyentran N / Tafreshi, Javad / Hernandez, Elvin A / Pai, Sudha M / Torres, Vilma I / Pai, Ramdas G

    Current cardiology reviews

    2012  Volume 9, Issue 1, Page(s) 55–62

    Abstract: Background: Reports in the literature indicate that specialty clinics focusing on management of patients with specific chronic disorders have a significant positive impact on patient outcomes. Atrial fibrillation (AF), one of the most common forms of ... ...

    Abstract Background: Reports in the literature indicate that specialty clinics focusing on management of patients with specific chronic disorders have a significant positive impact on patient outcomes. Atrial fibrillation (AF), one of the most common forms of cardiac arrhythmia, affects millions of patients. Outcome data regarding the impact of managing patients with AF are limited. We established a specialty clinic focusing on management of patients with AF. The objective of our study was to evaluate the outcomes of treating AF patients in this clinic.
    Methods: A team consisting of electrophysiologists and pharmacists designed a specific plan for managing and educating patients. This plan consisted of evaluation, implementation of an individualized treatment plan, patient education, medication management, and follow-up care. We reviewed the outcomes of patients who had clinic visits between November 2011 and March 2012. The primary outcome was the incidence of AF-related hospitalizations and stroke.
    Results: Seventy one patients were included in the analysis. Out of 71 patients, we identified 17 (23.9%) patients who were hospitalized. Two of these 17 hospitalized patients had ischemic stroke events.
    Conclusion: When compared to published data in the existing literature, managing AF patients in specialty clinics reduces the incidence of AF-related hospitalizations and stroke.
    MeSH term(s) Aged ; Aged, 80 and over ; Ambulatory Care Facilities ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/therapy ; Cohort Studies ; Electrophysiology ; Female ; Hospitalization/statistics & numerical data ; Humans ; Incidence ; Interdisciplinary Communication ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Patient Education as Topic ; Retrospective Studies ; Stroke/epidemiology ; Stroke/etiology
    Language English
    Publishing date 2012-10-23
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1875-6557
    ISSN (online) 1875-6557
    DOI 10.2174/157340313805076287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rhinovirus infection results in stronger and more persistent genomic dysregulation: Evidence for altered innate immune response in asthmatics at baseline, early in infection, and during convalescence.

    Heymann, Peter W / Nguyen, Huyen-Tran / Steinke, John W / Turner, Ronald B / Woodfolk, Judith A / Platts-Mills, Thomas A E / Martin, Lisa / He, Hua / Biagini Myers, Jocelyn / Lindsey, Mark / Sivaprasad, Umasundari / Medvedovic, Mario / Mahi, Naim / Carper, Holliday / Murphy, Deborah D / Patrie, James / Khurana Hershey, Gurjit K

    PloS one

    2017  Volume 12, Issue 5, Page(s) e0178096

    Abstract: Background: Rhinovirus (HRV) is associated with the large majority of virus-induced asthma exacerbations in children and young adults, but the mechanisms remain poorly defined.: Methods: Asthmatics and non-asthmatic controls were inoculated with HRV- ... ...

    Abstract Background: Rhinovirus (HRV) is associated with the large majority of virus-induced asthma exacerbations in children and young adults, but the mechanisms remain poorly defined.
    Methods: Asthmatics and non-asthmatic controls were inoculated with HRV-A16, and nasal epithelial samples were obtained 7 days before, 36 hours after, and 7 days after viral inoculation. RNA was extracted and subjected to RNA-seq analysis.
    Results: At baseline, 57 genes were differentially expressed between asthmatics and controls, and the asthmatics had decreased expression of viral replication inhibitors and increased expression of genes involved in inflammation. At 36 hours (before the emergence of peak symptoms), 1329 genes were significantly altered from baseline in the asthmatics compared to 62 genes in the controls. At this time point, asthmatics lacked an increase in IL-10 signaling observed in the controls. At 7 days following HRV inoculation, 222 genes were significantly dysregulated in the asthmatics, whereas only 4 genes were dysregulated among controls. At this time point, the controls but not asthmatics demonstrated upregulation of SPINK5.
    Conclusions: As judged by the magnitude and persistence of dysregulated genes, asthmatics have a substantially different host response to HRV-A16 infection compared with non-asthmatic controls. Gene expression differences illuminate biologically plausible mechanisms that contribute to a better understanding of the pathogenesis of HRV-induced asthma exacerbations.
    MeSH term(s) Adult ; Asthma/immunology ; Case-Control Studies ; Female ; Humans ; Immunity, Innate ; Male ; Picornaviridae Infections/immunology ; Rhinovirus/pathogenicity ; Young Adult
    Language English
    Publishing date 2017-05-26
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0178096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: An Application of Electrostatic Repulsion Hydrophilic Interaction Chromatography in Phospho- and Glycoproteome Profiling of Epicardial Adipose Tissue in Obesity Mouse

    Hookeun Lee / Jae Bum Kim / Jong-Moon Park / Injae Hwang / Trang HuyenTran

    Mass Spectrometry Letters, Vol 3, Iss 2, Pp 39-

    2012  Volume 42

    Abstract: ... digest of mouse proteome of epicardial adipose tissue with fat diet, 802 N-glycosylatedpeptides of 316 ...

    Abstract Phosphorylation and glycosylation are two of the most important and widespread post-translational modifications(PTMs) in an organism. Proteomics analysis of the PTMs has been challenged by low stoichiometry of the modified proteins andsuppression effects by high abundance proteins, typically no-functional house-keeping proteins. In this study, a novel methodwas applied for not only isolating PTM peptides from intact peptides but also concurrently characterizing of glyco- and phosphoproteomeusing electrostatic repulsion hydrophilic interaction chromatography (ERLIC) packed with silica coated by crosslinkedpolyethyleneimine. For 2 mg tryptic digest of mouse proteome of epicardial adipose tissue with fat diet, 802 N-glycosylatedpeptides of 316 glycoproteins and 159 phosphorylated peptides of 75 phosphoproteins were identified using HPLC chip/quadrupole time-of-flight (Q-TOF) tandem mass spectrometer.
    Keywords ERLIC ; Phosphoproteome enrichment ; Glycoproteome enrichment ; Simultaneous enrichment ; PTMs ; Analytical chemistry ; QD71-142
    Language English
    Publishing date 2012-06-01T00:00:00Z
    Publisher Korean Society for Mass Spectrometry
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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