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Article ; Online: A Potential Radiomics-Clinical Model for Predicting Failure of Lymph Node Control after Definite Radiotherapy in Locally Advanced Head and Neck Cancer.

Lee, Seunghak / Park, Sunmin / Rim, Chai Hong / Lee, Young Hen / Kwon, Soon Young / Oh, Kyung Ho / Yoon, Won Sup

2024 Volume 60, Issue 1

Abstract: Background and ... ...

Abstract	Background and Objectives
MeSH term(s)	Humans ; Radiomics ; Retrospective Studies ; Area Under Curve ; Head and Neck Neoplasms/diagnostic imaging ; Head and Neck Neoplasms/radiotherapy ; Lymph Nodes/diagnostic imaging ; Lymphatic Metastasis
Language	English
Publishing date	2024-01-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina60010092
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Article ; Online: Discrimination methods for diesel origin by analyzing fatty acid methyl ester (FAME) composition in diesel-contaminated soil.

Ko, Myoung-Soo / Lee, Seunghak

Scientific reports

2021 Volume 11, Issue 1, Page(s) 16245

Abstract: The biodiesel containing fatty acid methyl esters (FAMEs) are blended with refined diesel products. Here, we evaluate relative FAME composition ratio as a potential index to discriminate the pollution origin in diesel-contaminated soil. Artificially ... ...

Abstract	The biodiesel containing fatty acid methyl esters (FAMEs) are blended with refined diesel products. Here, we evaluate relative FAME composition ratio as a potential index to discriminate the pollution origin in diesel-contaminated soil. Artificially contaminated soil was prepared to mimic the release of petroleum products using four different refined diesels; in addition, the contaminated soil was put under natural weathering conditions. The variations in the relative FAME composition ratio was compared with those of the corresponding diesel origin using principal component analysis (PCA) for 60 days. All soil samples could be classified into four groups according to diesel origin using two principal components. The proposed method can be used to discriminate the specific diesel pollution origin in contaminated soils.
Language	English
Publishing date	2021-08-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-95780-3
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Article ; Online: Discrimination methods for diesel origin by analyzing fatty acid methyl ester (FAME) composition in diesel-contaminated soil

Myoung-Soo Ko / Seunghak Lee

Scientific Reports, Vol 11, Iss 1, Pp 1-

2021 Volume 6

Abstract: Abstract The biodiesel containing fatty acid methyl esters (FAMEs) are blended with refined diesel products. Here, we evaluate relative FAME composition ratio as a potential index to discriminate the pollution origin in diesel-contaminated soil. ... ...

Abstract	Abstract The biodiesel containing fatty acid methyl esters (FAMEs) are blended with refined diesel products. Here, we evaluate relative FAME composition ratio as a potential index to discriminate the pollution origin in diesel-contaminated soil. Artificially contaminated soil was prepared to mimic the release of petroleum products using four different refined diesels; in addition, the contaminated soil was put under natural weathering conditions. The variations in the relative FAME composition ratio was compared with those of the corresponding diesel origin using principal component analysis (PCA) for 60 days. All soil samples could be classified into four groups according to diesel origin using two principal components. The proposed method can be used to discriminate the specific diesel pollution origin in contaminated soils.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Influence of iron (hydr)oxide mineralogy and contents in aquifer sediments on dissolved organic carbon attenuations during aquifer storage and recovery.

Anggraini, Theresia May / An, Seongnam / Kim, Sang Hyun / Kwon, Man Jae / Chung, Jaeshik / Lee, Seunghak

Chemosphere

2024 Volume 351, Page(s) 141196

Abstract: Aquifer storage and recovery (ASR) is a promising approach for managing water resources that enhances water quality through biogeochemical reactions occurring within aquifers. Iron (hydr)oxides, which are the predominant metallic oxides in soil, play a ... ...

Abstract	Aquifer storage and recovery (ASR) is a promising approach for managing water resources that enhances water quality through biogeochemical reactions occurring within aquifers. Iron (hydr)oxides, which are the predominant metallic oxides in soil, play a crucial role in degrading dissolved organic carbon (DOC), primarily through a process known as dissimilatory iron reduction (DIR). However, the efficiency of this reaction varies depending on the mineralogy and composition of the aquifer, and this understanding is essential for adequate water quality in ASR. The objective of this study is to investigate the impact of iron (hydr)oxide on acetate, as an organic carbon source, attenuation during the ASR. To achieve this, three sets of laboratory sediment columns were prepared, each containing a different type of iron (hydr)oxide minerals: ferrihydrite, goethite, and hematite. Following an acclimation period of 28 days to simulate the microcosm within an aquifer, the columns were continuously supplied with the simulated river water spiked with acetate (DOC 40-60 mg L
MeSH term(s)	Iron/chemistry ; Dissolved Organic Matter ; Oxides ; Oxidation-Reduction ; Ferric Compounds/chemistry ; Groundwater ; Acetates ; Minerals ; Iron Compounds
Chemical Substances	ferric oxyhydroxide (87PZU03K0K) ; Iron (E1UOL152H7) ; goethite (1310-14-1) ; ferric oxide (1K09F3G675) ; Dissolved Organic Matter ; Oxides ; Ferric Compounds ; Acetates ; Minerals ; Iron Compounds
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2024.141196
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Article ; Online: Variable effects of soil organic matter on arsenic behavior in the vadose zone under different bulk densities.

Tran, Tho Huu Huynh / Kim, Sang Hyun / Lee, Hosub / Jo, Ho Young / Chung, Jaeshik / Lee, Seunghak

Journal of hazardous materials

2023 Volume 447, Page(s) 130826

Abstract: The nonstationary nature of water and oxygen content in the vadose zone determines various biogeochemical reactions regarding arsenic (As) therein, which affects the groundwater vulnerability to As contamination at a site. In the present study, we ... ...

Abstract	The nonstationary nature of water and oxygen content in the vadose zone determines various biogeochemical reactions regarding arsenic (As) therein, which affects the groundwater vulnerability to As contamination at a site. In the present study, we evaluated the effect of soil organic matter (OM) on the behavior of As using specifically designed soil columns that simulated the vadose zone. Three wet-dry cycles were applied to each of the four columns with different OM contents and bulk densities. OM was found to exhibit variable effects, either inhibiting or accelerating the mobilization of As, depending on bulk density. At a moderate bulk density (< 1.27 g/cm
Language	English
Publishing date	2023-01-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2023.130826
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Article ; Online: Unveiling interfacial interaction between antimony oxyanions and boehmite nanorods: Spectroscopic evidence and density functional theory analysis.

Lee, Seon Yong / Cho, Eun / Suh, Bong Lim / Choi, Jae-Woo / Lee, Seunghak / Kim, Jihan / Lee, Changha / Jung, Kyung-Won

Journal of hazardous materials

2024 Volume 469, Page(s) 133902

Abstract: In natural environments, the fate and migratory behavior of metalloid contaminants such as antimony (Sb) significantly depend on the interfacial reactivity of mineral surfaces. Although boehmite (γ-AlOOH) is widely observed in (sub)surface environments, ... ...

Abstract	In natural environments, the fate and migratory behavior of metalloid contaminants such as antimony (Sb) significantly depend on the interfacial reactivity of mineral surfaces. Although boehmite (γ-AlOOH) is widely observed in (sub)surface environments, its underlying interaction mechanism with Sb oxyanions at the molecular scale remains unclear. Considering Sb-contaminated environmental conditions in this study, we prepared boehmite under weakly acidic conditions for use in the systematic investigation of interfacial interactions with Sb(III) and Sb(V). The as-synthesized boehmite showed a nanorod morphology and comprised four crystal facets in the following order: 48.4% (010), 27.1% (101), 15.0% (001), and 9.5% (100). The combined results of spectroscopic analyses and theoretical calculations revealed that Sb(III) formed hydrogen bonding outer-sphere complexation on the (100), (010), and (001) facets and that Sb(V) preferred to form bidentate inner-sphere complexation via mononuclear edge-sharing configuration on the (100), (001), and (101) facets and binuclear corner-sharing configuration on the (010) facet. These findings indicate that the facet-mediated thermodynamic stability of the surface complexation determines the interaction affinity toward the Sb species. This work is the first to document the contribution of boehmite to (sub)surface media, improving the ability to forecast the fate and behavior of Sb oxyanions at mineral-water interfaces.
Language	English
Publishing date	2024-02-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2024.133902
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Article ; Online: Complex behavior of petroleum hydrocarbons in vadose zone: A holistic analysis using unsaturated soil columns.

An, Seongnam / Woo, Heesoo / Kim, Sang Hyun / Yun, Seong-Taek / Chung, Jaeshik / Lee, Seunghak

Chemosphere

2023 Volume 326, Page(s) 138417

Abstract: The migration of petroleum hydrocarbons in vadose zone involves complex coupled processes such as downward displacement and natural attenuation. Despite its significance in determining groundwater vulnerability to petroleum contamination and optimizing ... ...

Abstract	The migration of petroleum hydrocarbons in vadose zone involves complex coupled processes such as downward displacement and natural attenuation. Despite its significance in determining groundwater vulnerability to petroleum contamination and optimizing the remedial strategy, it has not been comprehensively studied in terms of overall processes under field-relevant conditions. In this study, a series of unsaturated soil column experiments were conducted by simulating subsurface diesel contamination within a vadose zone using different soil textures at different soil bulk densities and initial diesel concentrations, while partly exposing them to simulated precipitation. The results showed that the soil column with less fine fraction was favorable for the downward migration of diesel but unfavorable for its natural degradation. However, precipitation complicated the relative conductivities of multiple fluids (water, air, and diesel) through the pore network, therby decreasing diesel migration and degradation. For example, the downward migration of diesel in the SL column decreased by 8.4% under precipitation, while the overall attenuation rate dropped to almost 0.24% of its original state. Lowering bulk density (from 1.5 to 1.23 g/cm3), however, could enhance the attenuation rate presumably due to the secured void space for the incoming fluids. A high initial concentration of diesel (2%; w/w) inhibited its natural attenuation, while its influence on its vertical propagation after the precipitation was not significant. The present findings provide a mechanistic basis for approximating the behavior of petroleum hydrocarbons in a random vadose zone.
MeSH term(s)	Petroleum/metabolism ; Soil ; Soil Pollutants/analysis ; Hydrocarbons/metabolism ; Groundwater ; Biodegradation, Environmental
Chemical Substances	Petroleum ; Soil ; Soil Pollutants ; Hydrocarbons
Language	English
Publishing date	2023-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.138417
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Article ; Online: Synergetic effect of nitrate on dissolved organic carbon attenuation through dissimilatory iron reduction during aquifer storage and recovery.

Anggraini, Theresia May / An, Seongnam / Chung, Jaeshik / Kim, Eun-Ju / Kwon, Man Jae / Kim, Sang Hyun / Lee, Seunghak

Water research

2023 Volume 249, Page(s) 120954

Abstract: Aquifer storage and recovery (ASR) is a promising water management technique in terms of quantity and quality. During ASR, iron (Fe) (hydr)oxides contained in the aquifer play a crucial role as electron acceptors in attenuating dissolved organic carbon ( ... ...

Abstract	Aquifer storage and recovery (ASR) is a promising water management technique in terms of quantity and quality. During ASR, iron (Fe) (hydr)oxides contained in the aquifer play a crucial role as electron acceptors in attenuating dissolved organic carbon (DOC) in recharging water through dissimilatory iron reduction (DIR). Considering the preference of electron acceptors, nitrate (NO
MeSH term(s)	Nitrates ; Ferric Compounds ; Dissolved Organic Matter ; Iron/analysis ; Oxidation-Reduction ; Oxides ; Oxidants ; Water ; Ferrous Compounds ; Groundwater
Chemical Substances	Nitrates ; Ferric Compounds ; Dissolved Organic Matter ; Iron (E1UOL152H7) ; Oxides ; Oxidants ; Water (059QF0KO0R) ; Ferrous Compounds
Language	English
Publishing date	2023-11-30
Publishing country	England
Document type	Journal Article
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2023.120954
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Article ; Online: Robust multimodal fusion network using adversarial learning for brain tumor grading.

Jeong, Seung-Wan / Cho, Hwan-Ho / Lee, Seunghak / Park, Hyunjin

Computer methods and programs in biomedicine

2022 Volume 226, Page(s) 107165

Abstract: Background and objective: Gliomas are graded using multimodal magnetic resonance imaging, which provides important information for treatment and prognosis. When modalities are missing, the grading is degraded. We propose a robust brain tumor grading ... ...

Abstract	Background and objective: Gliomas are graded using multimodal magnetic resonance imaging, which provides important information for treatment and prognosis. When modalities are missing, the grading is degraded. We propose a robust brain tumor grading model that can handle missing modalities. Methods: Our method was developed and tested on Brain Tumor Segmentation Challenge 2017 dataset (n = 285) via nested five-fold cross-validation. Our method adopts adversarial learning to generate the features of missing modalities relative to the features obtained from a full set of modalities in the latent space. An attention-based fusion block across modalities fuses the features of each available modality into a shared representation. Our method's results are compared to those of two other models where 15 missing-modality scenarios are explicitly considered and a joint training approach with random dropouts is used. Results: Our method outperforms the two competing methods in classifying high-grade gliomas (HGGs) and low-grade gliomas (LGGs), achieving an area under the curve of 87.76% on average for all missing-modality scenarios. The activation maps derived with our method confirm that it focuses on the enhancing portion of the tumor in HGGs and on the edema and non-enhancing portions of the tumor in LGGs, which is consistent with prior expertise. An ablation study shows the added benefits of a fusion block and adversarial learning for handling missing modalities. Conclusion: Our method shows robust grading of gliomas in all cases of missing modalities. Our proposed network might have positive implications in glioma care by learning features robust to missing modalities.
MeSH term(s)	Humans ; Neoplasm Grading ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Glioma/diagnostic imaging ; Glioma/pathology ; Magnetic Resonance Imaging/methods ; Brain/pathology
Language	English
Publishing date	2022-09-29
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	632564-6
ISSN	1872-7565 ; 0169-2607
ISSN (online)	1872-7565
ISSN	0169-2607
DOI	10.1016/j.cmpb.2022.107165
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Article ; Online: Inverse estimation of multiple contaminant sources in three-dimensional heterogeneous aquifers with variable-density flows

Yoon, Seonkyoo / Lee, Seunghak / Zhang, Jiangjiang / Zeng, Lingzao / Kang, Peter K.

Journal of Hydrology. 2023 Feb., v. 617 p.129041-

2023

Abstract: Groundwater contamination is an exacerbating global issue that severely threatens human health. Subsurface remediation thus has gained increased interest in recent years. To effectively remediate subsurface contaminated sites, one needs to identify the ... ...

Abstract	Groundwater contamination is an exacerbating global issue that severely threatens human health. Subsurface remediation thus has gained increased interest in recent years. To effectively remediate subsurface contaminated sites, one needs to identify the locations of contaminant sources and characterize contaminant spreading. Groundwater contamination is often driven by multiple contaminant sources, making source identification problems challenging. Further, when the densities of dissolved contaminants and ambient groundwater differ, the resultant variable-density flows add complexity to the task of source identification. However, most previous studies are limited to a single source identification in a two-dimensional aquifer. This study presents a novel inversion method based on ensemble smoothing that identifies the locations of multiple contaminant sources in three-dimensional heterogeneous aquifer systems. A new covariance localization algorithm based on a clustering method is integrated into the inversion method, which improves the accuracy of multi-source identification. Using the proposed inversion framework, we successfully estimate the locations of multiple contaminant sources and three-dimensional permeability fields utilizing pressure and concentration data from monitoring wells. Further, we investigate and elucidate the effects of aquifer heterogeneity and variable-density flows on multiple source identification. We find that variable-density flow increases the data information contents and thus improves the inversion accuracy. This is the first-time demonstration of the effects of variable-density flow on the inversion accuracy of multi-source identification in three-dimensional heterogeneous aquifer systems.
Keywords	algorithms ; aquifers ; covariance ; groundwater ; groundwater contamination ; human health ; permeability ; remediation ; Inverse estimation ; Multiple contaminant sources ; 3D heterogeneous aquifer ; Ensemble smoothing ; Variable-density flows
Language	English
Dates of publication	2023-02
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	1473173-3
ISSN	1879-2707 ; 0022-1694
ISSN (online)	1879-2707
ISSN	0022-1694
DOI	10.1016/j.jhydrol.2022.129041
Database	NAL-Catalogue (AGRICOLA)

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