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  1. Article ; Online: Combined Tissue Transfer for Extensive Lower Limb Complex Defects: Flow-through Flaps, Chimera, and "Orochi" Flaps.

    Koshima, Isao

    Journal of reconstructive microsurgery

    2020  Volume 37, Issue 1, Page(s) 17–21

    Abstract: Perforator flaps can be raised anywhere in the body, with minimal donor-site deformity, and can be made into custom-made combined composite flaps, especially for severe complex defects such as osteomyelitis of the lower limbs. Here, we report on the ... ...

    Abstract Perforator flaps can be raised anywhere in the body, with minimal donor-site deformity, and can be made into custom-made combined composite flaps, especially for severe complex defects such as osteomyelitis of the lower limbs. Here, we report on the representative application of the combined tissue transfers for complex leg defects. For a wide range of complex defects in the lower extremity, it is necessary to perform reliable revascularization by bypass or flow-through type or vein graft. At the same time, a chimeric or "Orochi" type combined transfer using a minimally invasive perforator flaps and a well-vascularized bone flap are useful. In the case of nerve palsy, it could be possible to combine vascularized nerve flaps. Combined tissue transfers with less invasive donor will be more available in the future.
    MeSH term(s) Humans ; Lower Extremity/surgery ; Osteomyelitis/surgery ; Perforator Flap ; Reconstructive Surgical Procedures ; Soft Tissue Injuries/surgery
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605983-1
    ISSN 1098-8947 ; 0743-684X ; 0743-684X
    ISSN (online) 1098-8947 ; 0743-684X
    ISSN 0743-684X
    DOI 10.1055/s-0040-1715814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Long-necked reading man flap for distal dorsal finger defect reconstruction.

    Shimbo, Keisuke / Koshima, Isao

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2023  Volume 79, Page(s) 13–15

    MeSH term(s) Male ; Humans ; Reading ; Surgical Flaps ; Fingers/surgery ; Finger Injuries/surgery ; Soft Tissue Injuries/surgery ; Treatment Outcome
    Language English
    Publishing date 2023-02-07
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2023.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply.

    Roh, Solji / Koshima, Isao

    Journal of vascular surgery. Venous and lymphatic disorders

    2023  Volume 11, Issue 4, Page(s) 892–893

    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Letter
    ISSN 2213-3348
    ISSN (online) 2213-3348
    DOI 10.1016/j.jvsv.2023.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Combined Tissue Transfer for Extensive Lower Limb Complex Defects: Flow-through Flaps, Chimera, and “Orochi” Flaps

    Koshima, Isao

    Journal of Reconstructive Microsurgery

    (Lower Extremity Reconstruction)

    2020  Volume 37, Issue 01, Page(s) 17–21

    Abstract: Perforator flaps can be raised anywhere in the body, with minimal donor-site deformity, and can be made into custom-made combined composite flaps, especially for severe complex defects such as osteomyelitis of the lower limbs. Here, we report on the ... ...

    Series title Lower Extremity Reconstruction
    Abstract Perforator flaps can be raised anywhere in the body, with minimal donor-site deformity, and can be made into custom-made combined composite flaps, especially for severe complex defects such as osteomyelitis of the lower limbs. Here, we report on the representative application of the combined tissue transfers for complex leg defects. For a wide range of complex defects in the lower extremity, it is necessary to perform reliable revascularization by bypass or flow-through type or vein graft. At the same time, a chimeric or “Orochi” type combined transfer using a minimally invasive perforator flaps and a well-vascularized bone flap are useful. In the case of nerve palsy, it could be possible to combine vascularized nerve flaps. Combined tissue transfers with less invasive donor will be more available in the future.
    Keywords combined tissue transfer ; Orochi flap ; complex defect ; chimera flap ; flow-through flap
    Language English
    Publishing date 2020-10-07
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605983-1
    ISSN 1098-8947 ; 0743-684X ; 0743-684X
    ISSN (online) 1098-8947 ; 0743-684X
    ISSN 0743-684X
    DOI 10.1055/s-0040-1715814
    Database Thieme publisher's database

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  5. Article ; Online: Comparative study of conservative treatment and lymphaticovenular anastomosis with compression therapy for early-stage breast cancer-related lymphoedema.

    Shimbo, Keisuke / Kawamoto, Haruka / Koshima, Isao

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2023  Volume 88, Page(s) 390–396

    Abstract: This single-centre retrospective cohort study aimed to clarify the superiority of treatment by comparing the outcomes of lymphaticovenular anastomosis with compression therapy and conservative treatment centred on compression therapy in the early stage ... ...

    Abstract This single-centre retrospective cohort study aimed to clarify the superiority of treatment by comparing the outcomes of lymphaticovenular anastomosis with compression therapy and conservative treatment centred on compression therapy in the early stage of breast cancer-related lymphoedema. Data were collected from all patients treated for breast cancer-related lymphoedema between January 2015 and December 2022. The patients were classified into conservative treatment and surgical treatment groups. The upper extremity lymphoedema index value was calculated, based on five circumference values of the upper extremity and body mass index, to compare the 6-, 12-, 18- and 24-month outcomes between the groups. Of 101 patients with breast cancer-related lymphoedema, 81 (conservative treatment: 52; surgical treatment: 29) were included in the analysis. The therapeutic effect was significantly higher in the surgical treatment group than in the conservative treatment group, when comparing the rate of change in oedema at 6 (-6.6% ± 7.3% vs. 0.9% ± 7.5%; p < 0.001), 12 (-7.3% ± 6.2% vs. 2.9% ± 8.6%; p < 0.001), 18 (-7.6% ± 8.0% vs. 3.9% ± 9.2%; p < 0.001) and 24 (-5.6% ± 6.0% vs. 4.4% ± 10.7%; p < 0.001) months. The incidence of cellulitis increased in the conservative treatment group (from 9.6% to 15.4%), whereas it was suppressed in the surgical treatment group (from 13.8% to 0%). Conservative treatment centred on compression therapy increased oedema over time; however, lymphaticovenular anastomosis with compression therapy effectively reduced oedema.
    MeSH term(s) Humans ; Female ; Conservative Treatment ; Retrospective Studies ; Breast Neoplasms/complications ; Breast Neoplasms/surgery ; Breast Cancer Lymphedema/surgery ; Lymphedema/etiology ; Lymphedema/surgery ; Anastomosis, Surgical/adverse effects ; Edema
    Language English
    Publishing date 2023-11-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2023.11.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Conservative treatment versus lymphaticovenular anastomosis for early-stage lower extremity lymphedema.

    Shimbo, Keisuke / Kawamoto, Haruka / Koshima, Isao

    Journal of vascular surgery. Venous and lymphatic disorders

    2023  Volume 11, Issue 6, Page(s) 1231–1240

    Abstract: Objective: Several options for the treatment of lower extremity lymphedema (LEL) can be broadly classified into conservative treatment, such as compression garments and decongestive lymphatic therapy, and surgical treatment, such as lymphaticovenular ... ...

    Abstract Objective: Several options for the treatment of lower extremity lymphedema (LEL) can be broadly classified into conservative treatment, such as compression garments and decongestive lymphatic therapy, and surgical treatment, such as lymphaticovenular anastomosis (LVA). The purpose of our study was to clarify the superiority of these treatments by comparing the outcomes of LVA with those of conservative treatment for early-stage LEL.
    Methods: We performed a single-center, retrospective cohort study. The patients with LEL who presented to our department between January 2015 and December 2022 were identified and classified into two groups: conservative treatment and surgical treatment. The LEL indexes, calculated from the four lower extremity circumferences and the body mass index, were compared at the 6-, 12-, and 24-month follow-up between the two groups.
    Results: Of the 101 patients with LEL, 53 with 72 affected limbs (conservative treatment, 39 patients and 53 affected limbs; surgical treatment, 15 patients and 19 affected limbs) were included in the present analysis. The therapeutic effect for reducing edema, as determined by comparing the corrected LEL index at 12 months (103.7 ± 12.7 vs 91.9 ± 10.7; P = .005) and 24 months (103.1 ± 12.9 vs 83.8 ± 7.2; P < .001), was significantly higher in the surgical treatment group than that in the conservative treatment group. The conservative treatment group showed little change in the corrected LEL index at ≤24 months of follow-up (+3.1%; P = .299). In contrast, the surgical treatment group showed a significant reduction in edema at 24 months according to the corrected LEL index (-16.2%; P = .019).
    Conclusions: In early-stage LEL, conservative treatment centered on compression therapy alone only maintained edema (ie, edema did not worsen or improve). In contrast, LVA with compression therapy reduced edema.
    MeSH term(s) Humans ; Retrospective Studies ; Conservative Treatment/adverse effects ; Lymphatic Vessels/diagnostic imaging ; Lymphatic Vessels/surgery ; Lower Extremity/surgery ; Lymphedema/diagnostic imaging ; Lymphedema/surgery ; Anastomosis, Surgical ; Edema ; Treatment Outcome
    Language English
    Publishing date 2023-07-16
    Publishing country United States
    Document type Journal Article
    ISSN 2213-3348
    ISSN (online) 2213-3348
    DOI 10.1016/j.jvsv.2023.06.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Methotrexate-associated lymphoproliferative disorder presenting as an ulcer with tendon exposure on the dorsum of the hand: a case report and literature review.

    Kawamoto, Haruka / Shimbo, Keisuke / Koshima, Isao

    Wounds : a compendium of clinical research and practice

    2023  Volume 35, Issue 6, Page(s) E189–E192

    Abstract: Introduction: MTX-LPD is a complication that occurs during MTX treatment. Skin lesions in MTX-LPD are often subcutaneous nodules with occasional necrosis and ulceration. Although MTX-LPD regression is frequently observed upon discontinuation of oral MTX ...

    Abstract Introduction: MTX-LPD is a complication that occurs during MTX treatment. Skin lesions in MTX-LPD are often subcutaneous nodules with occasional necrosis and ulceration. Although MTX-LPD regression is frequently observed upon discontinuation of oral MTX treatment, delayed diagnosis of MTX-LPD with associated ulceration may lead to ulcer enlargement and the need for surgical procedures such as skin grafts.
    Case report: A 74-year-old female was diagnosed with RA and administered MTX for 3 years and 8 months. The patient presented with a 2-month-old ulcer on the dorsum of the hand. The ulcer size was 6.5 cm × 5 cm, and it was surrounded by an embankment tumor measuring 7 cm × 6 cm. Although a definitive diagnosis could not be made based on the biopsy specimen, excision of the ulcer-containing mass confirmed MTX-LPD diagnosis. MTX was discontinued, and free-flap reconstruction was performed 3 weeks after the first surgery. The postoperative period was uneventful, and MTX-LPD recurrence was not observed 10 months after the second surgery.
    Conclusion: Although MTX-LPD with ulceration is rare, it should be considered in cases of refractory ulcers in patients with RA. The discontinuation of MTX based on early MTX-LPD diagnosis is critical to avoid surgical procedures such as skin grafts and flap reconstruction.
    MeSH term(s) Female ; Humans ; Aged ; Infant ; Methotrexate/adverse effects ; Ulcer/chemically induced ; Ulcer/diagnosis ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Hand/pathology ; Lymphoproliferative Disorders/chemically induced ; Lymphoproliferative Disorders/diagnosis ; Lymphoproliferative Disorders/complications
    Chemical Substances Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 1214936-6
    ISSN 1943-2704 ; 1044-7946
    ISSN (online) 1943-2704
    ISSN 1044-7946
    DOI 10.25270/wnds/22103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Venous end-to-side anastomosis for free-flap reconstruction in the extremities: A case series and meta-analysis.

    Shimbo, Keisuke / Kawamoto, Haruka / Koshima, Isao

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2023  Volume 83, Page(s) 4–11

    Abstract: This case series aimed to investigate the result of venous end-to-side (ETS) anastomosis in the extremities to contribute to a meta-analysis to evaluate the postoperative complications of venous ETS anastomosis in the extremities. This was a single- ... ...

    Abstract This case series aimed to investigate the result of venous end-to-side (ETS) anastomosis in the extremities to contribute to a meta-analysis to evaluate the postoperative complications of venous ETS anastomosis in the extremities. This was a single-center case series and meta-analysis of patients who underwent venous ETS anastomosis for free-flap reconstruction of the extremities. We reviewed the records of 41 free flaps in 40 patients and performed a comprehensive search of PubMed, Scopus, and Web of Science for studies published from inception to December 2022. Primary outcomes were venous thrombosis, takebacks, and total and partial flap failures. Complication rates and confidence intervals were calculated using a random-effects model. In our case series, four (12.2%) patients with five flaps were taken back to the operating room, three (7.3%) flaps were due to venous thrombosis, and three (7.3%) flaps ultimately resulted in total flap failure. Our meta-analysis demonstrated the following complication rates: 4.0% (95% confidence interval [CI], 0-18.1%; I
    MeSH term(s) Humans ; Microsurgery/methods ; Veins/surgery ; Plastic Surgery Procedures ; Extremities/surgery ; Venous Thrombosis/etiology ; Venous Thrombosis/surgery ; Free Tissue Flaps/surgery ; Anastomosis, Surgical/methods ; Postoperative Complications/surgery ; Retrospective Studies
    Language English
    Publishing date 2023-05-07
    Publishing country Netherlands
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2023.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Linear scleroderma of the face treated by a superficial circumflex iliac artery perforator flap.

    Mizuta, Haruki / Koshima, Isao

    Archives of plastic surgery

    2021  Volume 48, Issue 5, Page(s) 524–525

    Language English
    Publishing date 2021-09-15
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2694943-X
    ISSN 2234-6171 ; 2234-6163
    ISSN (online) 2234-6171
    ISSN 2234-6163
    DOI 10.5999/aps.2021.00584
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A Case-control Analysis of the Knight's Move Technique in a Chicken Wing Microsurgery Model: Video Article.

    Kannan, Ruben Yap / Koshima, Isao

    Plastic and reconstructive surgery. Global open

    2021  Volume 9, Issue 3, Page(s) e3476

    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000003476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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