LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 91

Search options

  1. Article ; Online: Sonographic changes in uterine vein thrombosis during pregnancy on transvaginal ultrasound.

    Sato, Ayaka / Tanaka, Kunio / Sakuma, Moeko / Ikenoue, Satoru / Kasuga, Yoshifumi / Tanaka, Mamoru

    Journal of medical ultrasonics (2001)

    2023  

    Language English
    Publishing date 2023-12-19
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1396630-3
    ISSN 1613-2254 ; 0287-0592 ; 1346-4523
    ISSN (online) 1613-2254
    ISSN 0287-0592 ; 1346-4523
    DOI 10.1007/s10396-023-01395-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Association of maternal obesity with growth of fetal fractional limb volume.

    Ikenoue, Satoru / Akiba, Yohei / Ishii, Ryota / Otani, Toshimitsu / Kasuga, Yoshifumi / Tanaka, Mamoru

    Early human development

    2024  Volume 191, Page(s) 105990

    Abstract: Background: Maternal obesity influences birth weight and newborn adiposity. Fetal fractional limb volume has recently been introduced as a useful parameter for the proxy of fetal adiposity. However, the association between maternal adiposity and the ... ...

    Abstract Background: Maternal obesity influences birth weight and newborn adiposity. Fetal fractional limb volume has recently been introduced as a useful parameter for the proxy of fetal adiposity. However, the association between maternal adiposity and the growth of fetal fractional limb volume has not been examined.
    Aims: To investigate the association of maternal pre-pregnancy BMI with the growth of fetal fractional limb volume.
    Study design: Prospective cohort study.
    Subjects: Women with singleton uncomplicated pregnancies enrolled between July 2017 and June 2020.
    Outcome measures: Fetal fractional limb volume was assessed between 20 and 40 weeks' gestation, measured as cylindrical limb volume based on 50 % of the total diaphysis length. The measured fractional limb volume at each gestational week were converted to z-scores based on a previous report. The association between pre-pregnancy BMI and fetal fractional limb volume was examined. Maternal age, parity, gestational weight gain and fetal sex were considered as potential confounding variables.
    Results: Ultrasound scans of 455 fractional arm volume and thigh volume were obtained. Fractional limb volume increased linearly until the second trimester of gestation, then increased exponentially in the third trimester. Maternal pre-pregnancy BMI was significantly correlated with z-scores of fractional arm volume and thigh volume across gestation. The post-hoc analysis showed the association between pre-pregnancy BMI and fractional arm volume was significant especially between 34 and 40 weeks.
    Conclusions: Maternal obesity influences the growth pattern of fetal fractional limb volume. Fractional arm volume may potentially provide a useful surrogate marker of fetal nutritional status in late gestation.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Prospective Studies ; Obesity, Maternal ; Ultrasonography, Prenatal ; Birth Weight ; Pregnancy Trimester, Third ; Gestational Age ; Obesity/epidemiology
    Language English
    Publishing date 2024-03-19
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 752532-1
    ISSN 1872-6232 ; 0378-3782
    ISSN (online) 1872-6232
    ISSN 0378-3782
    DOI 10.1016/j.earlhumdev.2024.105990
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Clinical utility of 1-month postpartum random plasma glucose and glycated hemoglobin combined with pre-pregnancy body mass index for detecting postpartum glucose intolerance in Japanese women with gestational diabetes.

    Sugiyama, Kazutoshi / Saisho, Yoshifumi / Kasuga, Yoshifumi / Ochiai, Daigo / Itoh, Hiroshi

    Journal of diabetes investigation

    2021  Volume 12, Issue 12, Page(s) 2242–2246

    Abstract: During the coronavirus disease 2019 pandemic, the Japanese Society of Diabetes and Pregnancy proposed the use of random plasma glucose and glycated hemoglobin measured 1 month after delivery combined with pre-pregnancy body mass index to detect ... ...

    Abstract During the coronavirus disease 2019 pandemic, the Japanese Society of Diabetes and Pregnancy proposed the use of random plasma glucose and glycated hemoglobin measured 1 month after delivery combined with pre-pregnancy body mass index to detect postpartum glucose intolerance instead of carrying out the oral glucose tolerance test in women with gestational diabetes. We retrospectively evaluated the clinical utility of this strategy to detect postpartum glucose intolerance evaluated by the oral glucose tolerance test after delivery. A total of 275 Japanese women with gestational diabetes were included in the present study. The specificity of 1-month postpartum random plasma glucose and glycated hemoglobin combined with pre-pregnancy body mass index to predict postpartum glucose intolerance was 98.0%, with a negative predictive value of 72.6%. However, sensitivity was 6.4%, with a positive predictive value of 55.6%. In conclusion, this Japanese Society of Diabetes and Pregnancy strategy showed high specificity, but low sensitivity, for detecting glucose intolerance postpartum.
    MeSH term(s) Adult ; Blood Glucose/metabolism ; Body Mass Index ; Diabetes, Gestational/blood ; Diabetes, Gestational/diagnosis ; Diabetes, Gestational/epidemiology ; Female ; Glucose Intolerance/blood ; Glucose Intolerance/diagnosis ; Glucose Intolerance/epidemiology ; Glycated Hemoglobin/metabolism ; Humans ; Japan/epidemiology ; Postpartum Period/blood ; Pregnancy ; Retrospective Studies ; Time Factors
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2021-07-28
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2625840-7
    ISSN 2040-1124 ; 2040-1116
    ISSN (online) 2040-1124
    ISSN 2040-1116
    DOI 10.1111/jdi.13612
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Risk factors of neonatal hypoglycemia in neonates born to mothers with gestational diabetes.

    Arimitsu, Takeshi / Kasuga, Yoshifumi / Ikenoue, Satoru / Saisho, Yoshifumi / Hida, Mariko / Yoshino, Jun / Itoh, Hiroshi / Tanaka, Mamoru / Ochiai, Daigo

    Endocrine journal

    2023  Volume 70, Issue 5, Page(s) 511–517

    Abstract: Hypoglycemia is one of the most significant problems in neonates born to mothers with gestational diabetes (GDM). This study aimed to identify novel predictors of hypoglycemia in neonates born to mothers with GDM. A total of 443 term singleton infants ... ...

    Abstract Hypoglycemia is one of the most significant problems in neonates born to mothers with gestational diabetes (GDM). This study aimed to identify novel predictors of hypoglycemia in neonates born to mothers with GDM. A total of 443 term singleton infants from mothers diagnosed with GDM and cared for at Keio University Hospital between January 2013 and December 2019 were included in this study. Neonatal hypoglycemia was defined as hypoglycemia of less than 47 mg/dL at 1 or 2 or 4 h after birth, according to previous studies. Among 443 full-term singleton neonates born to mothers with GDM, 200 developed hypoglycemia (45%). Gestational weight gain (GWG), HbA1c at 1st trimester, HbA1c at GDM diagnosis, and the incidence of insulin therapy in the neonatal hypoglycemia group were significantly higher than those in the non-neonatal hypoglycemia group (p = 0.016, p = 0.032, p = 0.011, and p = 0.017, respectively). Regarding the multiple regression analysis adjusted for nulliparity, GWG, and gestational weeks at delivery, the odds ratio for maternal HbA1c ≥5.2% at 1st trimester was 1.63 (p = 0.034), and maternal insulin therapy during pregnancy was 1.72 (p = 0.015). In conclusion, HbA1c in the 1st trimester and insulin therapy during pregnancy were good predictors of hypoglycemia in neonates born to GDM mothers, especially when their HbA1c was 5.2% or more. Further research will be necessary to improve the perinatal management of hypoglycemia.
    MeSH term(s) Pregnancy ; Infant, Newborn ; Female ; Humans ; Diabetes, Gestational/drug therapy ; Diabetes, Gestational/epidemiology ; Diabetes, Gestational/diagnosis ; Glycated Hemoglobin ; Risk Factors ; Hypoglycemia/epidemiology ; Hypoglycemia/etiology ; Infant, Newborn, Diseases/epidemiology ; Infant, Newborn, Diseases/etiology ; Fetal Diseases ; Insulins
    Chemical Substances Glycated Hemoglobin ; Insulins
    Language English
    Publishing date 2023-03-15
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1151918-6
    ISSN 1348-4540 ; 0918-8959
    ISSN (online) 1348-4540
    ISSN 0918-8959
    DOI 10.1507/endocrj.EJ22-0521
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: A capture methyl-seq protocol with improved efficiency and cost-effectiveness using pre-pooling and enzymatic conversion.

    Hasegawa, Keita / Nakabayashi, Kazuhiko / Ishiwata, Keisuke / Kasuga, Yoshifumi / Hata, Kenichiro / Tanaka, Mamoru

    BMC research notes

    2023  Volume 16, Issue 1, Page(s) 141

    Abstract: Objective: The opportunities for sequencing-based methylome analysis of clinical samples are increasing. To reduce its cost and the amount of genomic DNA required for library preparation, we aimed to establish a capture methyl-seq protocol, which adopts ...

    Abstract Objective: The opportunities for sequencing-based methylome analysis of clinical samples are increasing. To reduce its cost and the amount of genomic DNA required for library preparation, we aimed to establish a capture methyl-seq protocol, which adopts pre-pooling of multiple libraries before hybridization capture and TET2/APOBEC-mediated conversion of unmethylated cytosine to thymine.
    Results: We compared a publicly available dataset generated by the standard Agilent protocol of SureSelect XT Human Methyl-Seq Kit and our dataset obtained by our modified protocol, EMCap, that adopted sample pre-pooling and enzymatic conversion. We confirmed that the quality of DNA methylation data was comparable between the two datasets. As our protocol, EMCap, is more cost-effective and reduces the amount of input genomic DNA, it would serve as a better choice for clinical methylome sequencing.
    MeSH term(s) Humans ; Sequence Analysis, DNA/methods ; Cost-Benefit Analysis ; DNA Methylation ; DNA/genetics ; Cytosine ; High-Throughput Nucleotide Sequencing/methods
    Chemical Substances DNA (9007-49-2) ; Cytosine (8J337D1HZY)
    Language English
    Publishing date 2023-07-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-023-06401-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Use of the Japanese gestational diabetes mellitus diagnostic strategy during the COVID-19 pandemic in Japan: A questionnaire survey.

    Kasuga, Yoshifumi / Miyakoshi, Kei / Yokoyama, Maki / Nakanishi, Sayuri / Iwama, Noriyuki / Ichikawa, Raishi / Abiko, Atsuko / Harashima, Shinichi / Sugiyama, Takashi

    The journal of obstetrics and gynaecology research

    2024  

    Abstract: Aim: Some concerns exist that diagnosis of gestational diabetes mellitus (GDM) may be missed when the simplified diagnostic criteria of the Japanese Society of Diabetes and Pregnancy (JSDP) for GDM (published during the COVID-19 pandemic) are used. ... ...

    Abstract Aim: Some concerns exist that diagnosis of gestational diabetes mellitus (GDM) may be missed when the simplified diagnostic criteria of the Japanese Society of Diabetes and Pregnancy (JSDP) for GDM (published during the COVID-19 pandemic) are used. Moreover, limited data is available regarding how widespread these diagnostic criteria are used when managing GDM during the COVID-19 pandemic. Therefore, this study aimed to determine how GDM diagnosis has changed during the COVID-19 pandemic in Japan.
    Methods: The changes in GDM diagnosis during the COVID-19 pandemic were investigated using an online questionnaire to 2159 obstetric facilities in Japan. The questionnaire collected data on facility type, awareness of Japanese GDM diagnostic strategies, modifications to diagnostic methods for early and late GDM, and opinions on GDM management, with the pandemic divided into seven periods.
    Results: We received responses from 593 facilities (27%). Approximately 90% of the facilities did not change their diagnostic process for early GDM or late GDM (occurring after 24 weeks gestation). However, during the COVID-19 pandemic, 19 facilities discontinued the use of 75-g oral glucose tolerance tests before 24 weeks of gestation, and 17 facilities discontinued it after 24 weeks of gestation, instead using the aforementioned Japanese GDM diagnostic strategy.
    Conclusions: Although a limited number of facilities modified their diagnostic method in response to the COVID-19 pandemic, this study demonstrated that those that adjusted their diagnostic method primarily used the Japanese COVID-19 GDM strategy by the JSDP.
    Language English
    Publishing date 2024-03-24
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1327307-3
    ISSN 1447-0756 ; 1341-8076
    ISSN (online) 1447-0756
    ISSN 1341-8076
    DOI 10.1111/jog.15929
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: New strategy for diagnosing abnormal glucose tolerance before 24 gestational weeks during the coronavirus disease 2019 pandemic.

    Kasuga, Yoshifumi / Saisho, Yoshifumi / Tamagawa, Masumi / Ikenoue, Satoru / Tanaka, Mamoru / Ochiai, Daigo

    Journal of diabetes investigation

    2021  Volume 12, Issue 11, Page(s) 2104–2105

    Abstract: The Japanese abnormal glucose tolerance before 24 gestational weeks diagnostic strategy in the evolving coronavirus disease 2019 pandemic published by the Japanese Society of Diabetes and Pregnancy. ...

    Abstract The Japanese abnormal glucose tolerance before 24 gestational weeks diagnostic strategy in the evolving coronavirus disease 2019 pandemic published by the Japanese Society of Diabetes and Pregnancy.
    MeSH term(s) Adult ; COVID-19/epidemiology ; Diabetes Mellitus/diagnosis ; Diabetes, Gestational/diagnosis ; Female ; Gestational Age ; Glucose Intolerance/diagnosis ; Glycated Hemoglobin/analysis ; Humans ; Japan/epidemiology ; Pregnancy ; Retrospective Studies ; SARS-CoV-2
    Chemical Substances Glycated Hemoglobin A
    Language English
    Publishing date 2021-05-24
    Publishing country Japan
    Document type Letter
    ZDB-ID 2625840-7
    ISSN 2040-1124 ; 2040-1116
    ISSN (online) 2040-1124
    ISSN 2040-1116
    DOI 10.1111/jdi.13570
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Transvaginal ultrasound features of the residual cervix in pregnancy after radical trachelectomy.

    Kasuga, Yoshifumi / Miyakoshi, Kei / Tanaka, Mamoru

    Journal of medical ultrasonics (2001)

    2020  Volume 47, Issue 2, Page(s) 335–337

    Language English
    Publishing date 2020-01-16
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1396630-3
    ISSN 1613-2254 ; 0287-0592 ; 1346-4523
    ISSN (online) 1613-2254
    ISSN 0287-0592 ; 1346-4523
    DOI 10.1007/s10396-020-01005-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Management of pregnancy after radical trachelectomy.

    Kasuga, Yoshifumi / Ikenoue, Satoru / Tanaka, Mamoru / Ochiai, Daigo

    Gynecologic oncology

    2021  Volume 162, Issue 1, Page(s) 220–225

    Abstract: Radical trachelectomy (RT) is a surgery for early-stage cervical cancer treatment that preserves the childbearing ability, and its use has become increasingly common worldwide. Thus, the rate of conception in women who have undergone RT is increasing. ... ...

    Abstract Radical trachelectomy (RT) is a surgery for early-stage cervical cancer treatment that preserves the childbearing ability, and its use has become increasingly common worldwide. Thus, the rate of conception in women who have undergone RT is increasing. However, pregnancy after RT is associated with a higher risk of several obstetric complications such as preterm delivery, preterm premature membrane rupture, and abnormal bleeding from varices at the site of uterovaginal anastomosis. Furthermore, since RT have a residual prophylactic cerclage, it is difficult to manage first- and second-trimester miscarriages. There is little previous data on the management of pregnancy after RT. In this review article, we summarize various management methods and experiences to provide a guide to clinicians for perinatal management after RT.
    MeSH term(s) Female ; Humans ; Pregnancy ; Pregnancy Outcome ; Trachelectomy
    Language English
    Publishing date 2021-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 801461-9
    ISSN 1095-6859 ; 0090-8258
    ISSN (online) 1095-6859
    ISSN 0090-8258
    DOI 10.1016/j.ygyno.2021.04.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Preterm delivery and hypertensive disorder of pregnancy were reduced during the COVID-19 pandemic: A single hospital-based study.

    Kasuga, Yoshifumi / Tanaka, Mamoru / Ochiai, Daigo

    The journal of obstetrics and gynaecology research

    2020  

    Keywords covid19
    Language English
    Publishing date 2020-10-07
    Publishing country Australia
    Document type Letter
    ZDB-ID 1327307-3
    ISSN 1447-0756 ; 1341-8076
    ISSN (online) 1447-0756
    ISSN 1341-8076
    DOI 10.1111/jog.14518
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top