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  1. Article ; Online: Transcatheter Aortic Valve Implantation: Addressing the Subsequent Risk of Permanent Pacemaker Implantation.

    Lauten, Philipp / Costello-Boerrigter, Lisa C / Goebel, Björn / Gonzalez-Lopez, David / Schreiber, Matthias / Kuntze, Thomas / Al Jassem, Mahmoud / Lapp, Harald

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 6

    Abstract: Transcatheter aortic valve implantation (TAVI) is now a commonly used therapy in patients with severe aortic stenosis, even in those patients at low surgical risk. The indications for TAVI have broadened as the therapy has proven to be safe and effective. ...

    Abstract Transcatheter aortic valve implantation (TAVI) is now a commonly used therapy in patients with severe aortic stenosis, even in those patients at low surgical risk. The indications for TAVI have broadened as the therapy has proven to be safe and effective. Most challenges associated with TAVI after its initial introduction have been impressively reduced; however, the possible need for post-TAVI permanent pacemaker implantation (PPI) secondary to conduction disturbances continues to be on the radar. Conduction abnormalities post-TAVI are always of concern given that the aortic valve lies in close proximity to critical components of the cardiac conduction system. This review will present a summary of noteworthy pre-and post-procedural conduction blocks, the best use of telemetry and ambulatory device monitoring to avoid unnecessary PPI or to recognize the need for late PPI due to delayed high-grade conduction blocks, predictors to identify those patients at greatest risk of requiring PPI, important CT measurements and considerations to optimize TAVI planning, and the utility of the MInimizing Depth According to the membranous Septum (MIDAS) technique and the cusp-overlap technique. It is stressed that careful membranous septal (MS) length measurement by MDCT during pre-TAVI planning is necessary to establish the optimal implantation depth before the procedure to reduce the risk of compression of the MS and consequent damage to the cardiac conduction system.
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10060230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cardiac natriuretic peptides: contributors to cardiac cachexia or possible anti-obesity agents or both?

    Costello-Boerrigter, Lisa C

    Diabetes

    2012  Volume 61, Issue 10, Page(s) 2403–2404

    MeSH term(s) Ghrelin/blood ; Humans ; Hunger/drug effects ; Male ; Natriuretic Peptide, Brain/pharmacology ; Satiation/drug effects
    Chemical Substances Ghrelin ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2012-09-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80085-5
    ISSN 1939-327X ; 0012-1797
    ISSN (online) 1939-327X
    ISSN 0012-1797
    DOI 10.2337/db12-0763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pre-procedural predictors for multiple clips in percutaneous edge-to-edge mitral valve repair.

    El Garhy, Mohammad / Lauer, Bernward / Göbel, Björn / Costello-Boerrigter, Lisa C / Salomon, Carsten / Lapp, Harald / Ohlow, Marc-Alexander

    The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

    2021  Volume 73, Issue 1, Page(s) 79

    Abstract: Background: Percutaneous mitral valve (MV) clipping for mitral regurgitation (MR) revolutionized MV repair; however, valve anatomies and pathologies vary. Often multiple clips are required, and predicting this pre-procedurally would be useful. We ... ...

    Abstract Background: Percutaneous mitral valve (MV) clipping for mitral regurgitation (MR) revolutionized MV repair; however, valve anatomies and pathologies vary. Often multiple clips are required, and predicting this pre-procedurally would be useful. We evaluated pre-procedural predictors for multiple clips.
    Results: We retrospectively analyzed 127 severe MR patients treated by mitral clipping between January 2011 and August 2018. Patients were grouped according to the use of a single (group I) or multiple clips (group II) and pre-procedure echocardiographs compared. No demographic differences existed except group II had more males (68.1%) than group I (48.3%). Mean left atrial diameter was larger in group II, 51 ± 9 mm, than group I, 48 ± 5 mm, p = 0.026. Mean mitral annular diameter differed: 34 ± 4mm (group II) versus 33 ± 3 mm (group I), p = 0.017. The vena contracta was broader in group II than group I (6.6 ± 1 mm vs. 6 ± 0.9 mm, p = 0.001). Severe mitral annular calcification occurred more in group I (36.2%) than group II (10.1%), p = 0.0001. On multivariate analysis, vena contracta width correlated positively with multiple clips (B 0.125, p = 0.013), but severe annular calcification correlated inversely (B - 0.35, p = 0.002).
    Conclusions: Vena contracta width and severe annular calcification are factors to consider when planning MV clipping.
    Language English
    Publishing date 2021-09-14
    Publishing country Germany
    Document type Journal Article
    ISSN 2090-911X
    ISSN (online) 2090-911X
    DOI 10.1186/s43044-021-00191-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The novel use of retrograde CTO PCI techniques as a rescue strategy for an acute right coronary artery occlusion due to iatrogenic dissection.

    Costello-Boerrigter, Lisa C / Salomon, Carsten / Bufe, Alexander / Lapp, Harald

    Journal of cardiology cases

    2017  Volume 17, Issue 3, Page(s) 89–91

    Abstract: Coronary artery dissection is a known complication of percutaneous coronary intervention (PCI). Such dissections are often treated by antegrade PCI. When antegrade PCI fails, the options become limited to conservative management or coronary artery bypass ...

    Abstract Coronary artery dissection is a known complication of percutaneous coronary intervention (PCI). Such dissections are often treated by antegrade PCI. When antegrade PCI fails, the options become limited to conservative management or coronary artery bypass grafting (CABG). CABG comes with its own risks, and conservative management can result in a potentially larger infarct. Here we present a novel use of retrograde chronic total occlusion (CTO) PCI techniques to treat an iatrogenic, type D dissection of the right coronary artery in a young male with an acute coronary syndrome. Reentrance of the true lumen by standard antegrade approaches failed. The rescue strategy using a retrograde CTO PCI approach not only had advantages over surgery and conservative management, but also over antegrade PCI. A soft wire, designed for collaterals, was used to "surf" the dissection and reach the antegrade guiding catheter. Thus, the true lumen could be used. This novel approach provided the advantages both of preserving major side branches, which are often lost with antegrade PCI approaches, and of not unnecessarily puncturing the dissection membrane. <
    Language English
    Publishing date 2017-12-02
    Publishing country Japan
    Document type Case Reports
    ISSN 1878-5409
    ISSN 1878-5409
    DOI 10.1016/j.jccase.2017.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Heart failure: furosemide--to DOSE or not to DOSE, that is the question.

    Costello-Boerrigter, Lisa C / Burnett, John C

    Nature reviews. Cardiology

    2011  Volume 8, Issue 7, Page(s) 365–366

    MeSH term(s) Biomarkers ; Disease Progression ; Diuretics/therapeutic use ; Furosemide/therapeutic use ; Heart Failure/drug therapy ; Humans
    Chemical Substances Biomarkers ; Diuretics ; Furosemide (7LXU5N7ZO5)
    Language English
    Publishing date 2011-05-31
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2490375-9
    ISSN 1759-5010 ; 1759-5002
    ISSN (online) 1759-5010
    ISSN 1759-5002
    DOI 10.1038/nrcardio.2011.74
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Controlling the flood gates: vaptans, furosemide and the quest for a renal protective diuresis.

    Costello-Boerrigter, Lisa C / Burnett, John C

    Journal of cardiac failure

    2011  Volume 17, Issue 12, Page(s) 990–992

    MeSH term(s) Antidiuretic Hormone Receptor Antagonists ; Benzazepines/therapeutic use ; Diuretics/therapeutic use ; Female ; Furosemide/therapeutic use ; Heart Failure/drug therapy ; Heart Failure, Systolic/drug therapy ; Humans ; Kidney/drug effects ; Male ; Sodium Potassium Chloride Symporter Inhibitors/therapeutic use
    Chemical Substances Antidiuretic Hormone Receptor Antagonists ; Benzazepines ; Diuretics ; Sodium Potassium Chloride Symporter Inhibitors ; conivaptan (0NJ98Y462X) ; tolvaptan (21G72T1950) ; Furosemide (7LXU5N7ZO5)
    Language English
    Publishing date 2011-12
    Publishing country United States
    Document type Comment ; Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2011.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pulmonary vein isolation using second-generation single-shot devices: not all the same?

    Seidl, Philipp / Steinborn, Frank / Costello-Boerrigter, Lisa / Surber, Ralf / Schulze, Paul C / Böttcher, Christine / Sommermeier, Andreas / Mattea, Violeta / Simeoni, Roland / Malur, Frank Michael / Lapp, Harald / Schade, Anja

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2020  Volume 60, Issue 3, Page(s) 521–528

    Abstract: Introduction: Single-shot devices have been developed to simplify pulmonary vein isolation (PVI). Randomized studies of the second-generation cryoballoon (CB 2nd) demonstrated excellent results. There are limited data comparing results of circular ... ...

    Abstract Introduction: Single-shot devices have been developed to simplify pulmonary vein isolation (PVI). Randomized studies of the second-generation cryoballoon (CB 2nd) demonstrated excellent results. There are limited data comparing results of circular pulmonary vein ablation catheter (PVAC) with conventional RF ablation or CB for PVI.
    Objective: Using a sequential registry cohort and a prospective randomized study, we aimed to compare the acute and long-term results of CB 2nd and PVAC Gold.
    Methods: In the registry, consecutive patients with paroxysmal atrial fibrillation (AF) undergoing their first PVI were included. The preferred method used was PVAC Gold in 2014 and CB 2nd in 2015. Subsequently, a randomized study (PVAC vs. CB 2nd) was performed. Ablation success was measured as freedom of AF or atrial tachycardias (AT) off antiarrhythmic drugs.
    Results: In the registry cohort, PVAC Gold was used in 60 patients and CB 2nd in 56 patients (age 66 ± 11 years, 52% male, LAD 43 ± 6). In the randomized study, 20 patients were treated with PVAC Gold and 22 with CB 2nd (age 67 ± 9; 43% men, LAD 40 ± 7 mm). During a mean follow up of 13.2 ± 3.6 months, success was 54% in PVAC Gold patients and 81% in CB 2nd cases (p = 0.001). In the randomized study 12 months success was 50% versus 86%, p < 0.05. Complications occurred rare in both groups.
    Conclusions: Our registry data and the randomized study both suggest superiority of PVI using CB 2nd as compared with PVI using PVAC Gold.
    MeSH term(s) Aged ; Atrial Fibrillation/surgery ; Catheter Ablation ; Cryosurgery ; Female ; Humans ; Infant, Newborn ; Male ; Prospective Studies ; Pulmonary Veins/surgery ; Treatment Outcome
    Language English
    Publishing date 2020-05-15
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-020-00751-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Natriuretic peptides in the diagnosis and management of chronic heart failure.

    Boerrigter, Guido / Costello-Boerrigter, Lisa C / Burnett, John C

    Heart failure clinics

    2009  Volume 5, Issue 4, Page(s) 501–514

    Abstract: Circulating levels of the BNP system can help in the diagnosis of cardiovascular disease and provide prognostic information not only for patients who have HF but also for the general population and other patient groups. Changes over time also carry ... ...

    Abstract Circulating levels of the BNP system can help in the diagnosis of cardiovascular disease and provide prognostic information not only for patients who have HF but also for the general population and other patient groups. Changes over time also carry prognostic information, and studies are assessing BNP-guided treatment strategies. With the identification of circulating molecular forms of BNP, new insights regarding the biology of the BNP system are emerging that may improve the diagnostic and prognostic value of BNP. Likewise, accounting for rs198389 (a common single nucleotide polymorphism that increases BNP levels) may help to further refine the use of components of the BNP system as biomarkers.
    MeSH term(s) Biomarkers/blood ; Chronic Disease ; Heart Failure/blood ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Natriuretic Peptide, Brain/blood ; Natriuretic Peptide, Brain/physiology ; Natriuretic Peptides/blood ; Natriuretic Peptides/physiology ; Prognosis ; Time Factors
    Chemical Substances Biomarkers ; Natriuretic Peptides ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2009-07-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2212019-1
    ISSN 1551-7136
    ISSN 1551-7136
    DOI 10.1016/j.hfc.2009.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pharmacology of vasopressin antagonists.

    Costello-Boerrigter, Lisa C / Boerrigter, Guido / Burnett, John C

    Heart failure reviews

    2008  Volume 14, Issue 2, Page(s) 75–82

    Abstract: Congestive heart failure (CHF) is characterized by fluid and water retention, which frequently is a therapeutic challenge. Most conventional diuretics act primarily as saluretics, i.e. they inhibit renal tubular electrolyte reabsorption, which due to ... ...

    Abstract Congestive heart failure (CHF) is characterized by fluid and water retention, which frequently is a therapeutic challenge. Most conventional diuretics act primarily as saluretics, i.e. they inhibit renal tubular electrolyte reabsorption, which due to osmotic pressure promotes excretion of isotonic fluid. Arginine vasopressin (AVP) via the V(1A) receptor vasoconstricts and via the V(2) receptor promotes water reabsorption in the renal collecting duct by inserting aquaporin-2 water channels into the luminal membrane. Novel V(2) receptor antagonists act as powerful aquaretics, i.e. they excrete free water. We review the pharmacology of non-selective V(1A)/V(2) receptor antagonists and selective V(2) receptor antagonists currently in clinical development.
    MeSH term(s) Antidiuretic Hormone Receptor Antagonists ; Arginine Vasopressin/metabolism ; Azepines/pharmacology ; Azepines/therapeutic use ; Benzamides/pharmacology ; Benzamides/therapeutic use ; Benzazepines/pharmacology ; Benzazepines/therapeutic use ; Benzodiazepines/pharmacology ; Benzodiazepines/therapeutic use ; Heart Failure/complications ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Humans ; Morpholines/pharmacology ; Morpholines/therapeutic use ; Pyrroles ; Receptors, Vasopressin/classification ; Spiro Compounds/pharmacology ; Spiro Compounds/therapeutic use ; Tolvaptan
    Chemical Substances Antidiuretic Hormone Receptor Antagonists ; Azepines ; Benzamides ; Benzazepines ; Morpholines ; Pyrroles ; RWJ-351647 ; Receptors, Vasopressin ; Spiro Compounds ; conivaptan (0NJ98Y462X) ; Arginine Vasopressin (113-79-1) ; Benzodiazepines (12794-10-4) ; Tolvaptan (21G72T1950) ; lixivaptan (8F5X4B082E) ; satavaptan (AJS8S3P31H)
    Language English
    Publishing date 2008-09-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1336499-6
    ISSN 1573-7322 ; 1382-4147
    ISSN (online) 1573-7322
    ISSN 1382-4147
    DOI 10.1007/s10741-008-9108-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A new role for the natriuretic peptides: metabolic regulators of the adipocyte.

    Costello-Boerrigter, Lisa C / Burnett, John C

    Journal of the American College of Cardiology

    2009  Volume 53, Issue 22, Page(s) 2078–2079

    MeSH term(s) Adipocytes/metabolism ; Adiponectin/biosynthesis ; Adiponectin/blood ; Heart Failure/blood ; Heart Failure/metabolism ; Humans ; Natriuretic Peptides/blood ; Natriuretic Peptides/physiology
    Chemical Substances Adiponectin ; Natriuretic Peptides
    Language English
    Publishing date 2009-05-27
    Publishing country United States
    Document type Comment ; Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2009.02.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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