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Article ; Online: Oculo-digital sign.

Rym, Maamouri / Abir, Boussetta / Meriem, Ouederni / Monia, Cheour

2023 Volume 59, Issue 10, Page(s) 1169–1170

Language	English
Publishing date	2023-08-03
Publishing country	Australia
Document type	Case Reports
ZDB-ID	1024476-1
ISSN	1440-1754 ; 1034-4810
ISSN (online)	1440-1754
ISSN	1034-4810
DOI	10.1111/jpc.16474
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Article ; Online: Attitudes of ophthalmologists towards pharmaceutical promotion.

Maamouri, Rym / Abid, Asma / Houman, Yasmine / Ouederni, Meriem / Cheour, Monia

La Tunisie medicale

2024 Volume 101, Issue 8-9, Page(s) 670–673

Abstract: Introduction: The interaction between physicians and pharmaceutical industry highlighted many issues lately concerning their influence on physician's attitude and their prescribing behavior.: Aim: To evaluate the attitudes of Tunisian ophthalmologist ...

Abstract	Introduction: The interaction between physicians and pharmaceutical industry highlighted many issues lately concerning their influence on physician's attitude and their prescribing behavior. Aim: To evaluate the attitudes of Tunisian ophthalmologist towards pharmaceutical promotion. Methods: Data was collected through an auto-administered anonymous questionnaire elaborated in French that was distributed to 160 ophthalmologists (residents and specialists) working in hospitals or private practices in four Tunisian governorates (Tunis, Sousse, Monastir and Sfax). Results: One hundred and two valid responses were received. Twenty-nine respondents (28.43%) estimated the number of visits by pharmaceutical representatives (PR) at 11 to 20 times during the last year. Most physicians considered guides (94%), drug samples (88%), articles (86%), stationery (81%), sponsorship of overseas conferences (72%) and international trips to symposia organized by pharmaceutical industries (58%), as appropriate gifts. Over 80% of doctors agreed that promotional activities by drug companies were appropriate. Accepting sponsorship from a pharmaceutical company for a partner to attend a meeting was considered inappropriate by 79% of ophthalmologists. Eighty-eight percent of the respondents agreed that receiving gifts will increase their prescription of the company's drug. However, they perceived themselves to be less influenced than their colleagues (p=0.011). Eighty-six percent of ophthalmologists reported training about how to interact with PR to be insufficient. Conclusions: Despite the role of PR in supporting research, ethical issues may arise through their interactions with healthcare professionals. Training about pharmaceutical promotion and appropriate ways to deal with it are lacking in Tunisian medical schools' curricula, leaving future doctors unprepared to deal with pharmaceutical influences.
MeSH term(s)	Humans ; Ophthalmologists ; Physicians ; Curriculum ; Health Personnel ; Pharmaceutical Preparations
Chemical Substances	Pharmaceutical Preparations
Language	English
Publishing date	2024-03-06
Publishing country	Tunisia
Document type	Journal Article
ZDB-ID	128627-4
ISSN	2724-7031 ; 0041-4131
ISSN (online)	2724-7031
ISSN	0041-4131
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Article ; Online: Surgical management of lifebuoy cataract.

Maamouri, Rym / Ouederni, Meriem / Gharbi, Zeineb / Cheour, Monia

Indian journal of ophthalmology

2023 Volume 71, Issue 6, Page(s) 2575–2577

Abstract: Lifebuoy cataract is a rare form of congenital cataract with anatomical characteristics. Herein, we present a case of an otherwise healthy 42-year-old female with a long-standing history of blurred vision. Examination showed the presence of esotropia and ...

Abstract	Lifebuoy cataract is a rare form of congenital cataract with anatomical characteristics. Herein, we present a case of an otherwise healthy 42-year-old female with a long-standing history of blurred vision. Examination showed the presence of esotropia and bilateral horizontal nystagmus. Visual acuity was limited to light perception in both eyes. Slit-lamp examination showed a calcified lens capsule with the absence of lens material in the right eye and the presence of an annular cataract in the left eye, corresponding to a unilateral lifebuoy cataract. She underwent cataract surgery with intraocular lens implantation. We report the clinical findings, anterior segment optical coherence tomography (AS-OCT), and surgical management tips. We noticed that during surgery, both anterior capsulorhexis and central membrane removal were the most challenging steps due to the absence of central nucleus and the strong adherence of central membrane to the anterior hyaloid.
MeSH term(s)	Female ; Humans ; Adult ; Lens Implantation, Intraocular/methods ; Cataract Extraction ; Cataract/complications ; Cataract/diagnosis ; Cataract/congenital ; Capsulorhexis ; Lens Capsule, Crystalline/surgery
Language	English
Publishing date	2023-06-15
Publishing country	India
Document type	Case Reports ; Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/IJO.IJO_284_23
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Article: Posterior Microphthalmos Pigmentary Retinopathy Syndrome with Angle-Closure Glaucoma: A Case Report.

Sassi, Hela / Ammar, Khaled / Ouederni, Meriem / Cheour, Monia

Journal of current ophthalmology

2023 Volume 34, Issue 4, Page(s) 474–477

Abstract: Purpose: To describe a particular form of posterior microphthalmos pigmentary retinopathy syndrome (PMPRS) with an atypical clinical presentation of pigment retinal dystrophy and an association to an inconstant complication which is angle-closure ... ...

Abstract	Purpose: To describe a particular form of posterior microphthalmos pigmentary retinopathy syndrome (PMPRS) with an atypical clinical presentation of pigment retinal dystrophy and an association to an inconstant complication which is angle-closure glaucoma (ACG). Methods: A 40-year-old male patient with ACG on maximal topical treatment was referred to our department for uncontrolled intraocular pressure. Best-corrected visual acuity was 2/10 in the right eye and light perception in the left eye. Intraocular pressure was 36 mmHg bilaterally. He had 360° peripheral anterior synechiae on gonioscopy. Fundus examination revealed total cupping with pale retinal lesions in both eyes and a few pigment deposits in the midperiphery of the right eye. Multimodal imaging was done. Results: Fundus autofluorescence revealed patchy areas of hypoautofluorescence. Optical coherence tomography (OCT) showed bilateral foveoschisis and macular folds. Anterior segment OCT showed a circumferential iridocorneal angle closure. Axial length measured with ultrasound biomicroscopy was 18.4 mm in the right eye and 18.1 in the left eye. Electroretinogram revealed attenuated scotopic responses. The patient was diagnosed with nanophthalmos-retinitis pigmentosa (RP)-foveoschisis syndrome complicated with ACG. A combined surgery with phacoemulsification - anterior vitrectomy - intraocular lens implantation and trabeculectomy was performed in both eyes with a satisfactory outcome. Conclusions: In its typical forms, PMPR syndrome is an association of nanophthalmos - RP - foveoschisis and optic nerve head (ONH) drusen. Incomplete phenotypes may lack ONH drusen or foveoschisis. Patients with PMPRS have to be screened for iridocorneal angle synechia and ACG.
Language	English
Publishing date	2023-04-29
Publishing country	India
Document type	Case Reports
ISSN	2452-2325
ISSN	2452-2325
DOI	10.4103/joco.joco_145_22
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Article ; Online: A membranous nephropathy in a 5 year-old boy: and if that's not all? A nephrology quiz.

Boussetta, Abir / Jellouli, Manel / Hajji, Meriem / Rekaya, Samia / Ouederni, Monia / Abderrahim, Ezzeddine / Gargah, Tahar

Journal of nephrology

2023

Language	English
Publishing date	2023-12-06
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1093991-x
ISSN	1724-6059 ; 1120-3625 ; 1121-8428
ISSN (online)	1724-6059
ISSN	1120-3625 ; 1121-8428
DOI	10.1007/s40620-023-01821-7
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Article ; Online: Multinodular scleritis in a patient with rheumatoid arthritis.

Ouederni, Meriem / Sassi, Hela / Cheour, Monia

Clinical rheumatology

2021 Volume 40, Issue 10, Page(s) 4359–4360

MeSH term(s)	Arthritis, Rheumatoid/complications ; Humans ; Scleritis/complications
Language	English
Publishing date	2021-04-16
Publishing country	Germany
Document type	Editorial
ZDB-ID	604755-5
ISSN	1434-9949 ; 0770-3198
ISSN (online)	1434-9949
ISSN	0770-3198
DOI	10.1007/s10067-021-05736-1
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Article ; Online: Swept Source OCT in monitoring uveal effusion after trabeculectomy in a nanophtalmic eye.

Ouederni, Meriem / Nefaa, Fehmy / Maamouri, Rym / Cheour, Monia

La Tunisie medicale

2022 Volume 99, Issue 10, Page(s) 961–963

Abstract: Uveal effusion syndrome describes serous detachments of the choroid and ciliary body with exudative retinal detachment. It is a complication following glaucoma filtering surgeries such as trabeculectomy especially in nanophthalmic eyes. We report a rare ... ...

Abstract	Uveal effusion syndrome describes serous detachments of the choroid and ciliary body with exudative retinal detachment. It is a complication following glaucoma filtering surgeries such as trabeculectomy especially in nanophthalmic eyes. We report a rare case of a 42-year-old-woman, with nanophtalmos, who developed posterior serous retinal detachment and uveal effusions after trabeculectomy for chronic angle closure glaucoma. The patient was put on oral steroids with good clinical outcome. Anterior Segment OCT allowed monitoring of iridocorneal angle and anterior chamber depth, Swept Source OCT was useful for monitoring retinal reattachment and choroidal thickness.
MeSH term(s)	Adult ; Female ; Glaucoma/diagnosis ; Glaucoma/surgery ; Humans ; Retinal Detachment/diagnosis ; Retinal Detachment/etiology ; Retinal Detachment/surgery ; Trabeculectomy/adverse effects
Language	English
Publishing date	2022-03-15
Publishing country	Tunisia
Document type	Case Reports ; Journal Article
ZDB-ID	128627-4
ISSN	2724-7031 ; 0041-4131
ISSN (online)	2724-7031
ISSN	0041-4131
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Article ; Online: Clinical features and predictors of osteoarticular manifestations in common variable immunodeficiency.

Ben Khaled, Monia / Merdassi, Amani / Rekaya, Samia / Fraj, Ilhem Ben / Lamouchi, Takwa / Zaiter, Ikram / Kouki, Ridha / Bejaoui, Mohamed / Mellouli, Fethi / Ouederni, Monia

Clinical rheumatology

2023 Volume 42, Issue 11, Page(s) 3123–3129

Abstract: Introduction: This study aimed to assess osteoarticular manifestations in patients with common variable immunodeficiency (CIVD) and to identify the predictive factors.: Methods: This was a retrospective and prognostic study conducted in the ... ...

Abstract	Introduction: This study aimed to assess osteoarticular manifestations in patients with common variable immunodeficiency (CIVD) and to identify the predictive factors. Methods: This was a retrospective and prognostic study conducted in the pediatrics: immuno-hematology and stem cell transplantation department, including patients who fit the definition of CVID. A Cox model analysis was used to identify predictive factors. Results: A total of 36 patients were enrolled. Osteoarticular involvement was noted in 15 patients (42%) with a cumulative incidence of 90% after a median follow-up of 25 years. Non-infectious manifestations were reported in 14 patients (39%). The cumulative risk of inflammatory or autoimmune osteoarticular etiology was 74%. Well-characterized rheumatic diseases were retained in six patients and unlabeled autoimmune or inflammatory mechanism in five cases. Bone mineral density revealed osteoporosis in six cases leading to a cumulative risk of degenerative complications of 72%. The cumulative incidence of infectious complications was 17%. In multivariate analysis, predictors of osteoarticular complications were low body weight (HR = 8.67, CI: 1.496-50.278, p = 0.01) and hepatomegaly at diagnosis (HR = 6.2, CI: 1.537-25.075, p = 0.01). Reduced CD4 cells rate < 600 cells/mm Conclusions: Osteoarticular manifestations have emerged as a real health problem for CVID patients. Risk increases with low body weight, hepatomegaly, chronic diarrhea, iron deficiency, and CD4 cells rate under 600 cell/mm
MeSH term(s)	Humans ; Child ; Common Variable Immunodeficiency/complications ; Common Variable Immunodeficiency/diagnosis ; Common Variable Immunodeficiency/epidemiology ; Retrospective Studies ; Hepatomegaly ; Diarrhea ; Iron Deficiencies ; Body Weight ; Autoimmunity
Language	English
Publishing date	2023-07-28
Publishing country	Germany
Document type	Journal Article
ZDB-ID	604755-5
ISSN	1434-9949 ; 0770-3198
ISSN (online)	1434-9949
ISSN	0770-3198
DOI	10.1007/s10067-023-06722-5
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Article: Quantitative Analysis of Microvascular Network with Optical Coherence Tomography Angiography and its Correlation with Visual Acuity in Retinal Vein Occlusion.

Ouederni, Meriem / Khalifa, Mohamed Ben Hadj / Sassi, Hela / Nefaa, Fehmy / Ayed, Oumaima / Cheour, Monia

Journal of current ophthalmology

2022 Volume 33, Issue 4, Page(s) 453–460

Abstract: Purpose: To analyze the macular microvascular network and the correlations between visual acuity and quantitative parameters using optical coherence tomography angiography (OCTA) in eyes with retinal vein occlusion (RVO).: Methods: We conducted a ... ...

Abstract	Purpose: To analyze the macular microvascular network and the correlations between visual acuity and quantitative parameters using optical coherence tomography angiography (OCTA) in eyes with retinal vein occlusion (RVO). Methods: We conducted a prospective cross-sectional study including patients with unilateral RVO. We performed 4.5 mm × 4.5 mm macular OCTA angiograms for assessment of quantitative parameters in both superficial and deep capillary plexuses (SCP, DCP). Area of foveal avascular zone (FAZ), vascular density (VD), skeleton density (SD), fractal dimension (FD), vessel diameter index (VDI), and lacunarity (LAC) were analyzed. Results: Seventy eyes of 35 patients were enrolled. As compared to fellow eyes, OCTA analysis in eyes with RVO showed larger FAZ, lower VD, lower SD, lower FD, higher VDI, and increased LAC in both plexuses (All Conclusions: OCTA provides quantitative parameters to analyze retinal microvasculature in eyes with RVO. These OCTA biomarkers could be used to predict the impact of macular ischemia and capillary dropout on visual acuity in RVO.
Language	English
Publishing date	2022-01-06
Publishing country	India
Document type	Journal Article
ISSN	2452-2325
ISSN	2452-2325
DOI	10.4103/joco.joco_163_21
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Article ; Online: Incidence and risk factors for osteonecrosis of the femoral head in five hundred and ten sickle cell disease paediatric patients.

Ouederni, Monia / Rouag, Hatem / Ben Fraj, Ilhem / Rekaya, Samia / Kouki, Ridha / Lamouchi, Takwa / Zaiter, Ikram / Mellouli, Fethi / Bejaoui, Mohamed / Ben Khaled, Monia

International orthopaedics

2023 Volume 47, Issue 12, Page(s) 2941–2952

Abstract: Purpose: Osteonecrosis of the femoral head (ONFH) is a degenerative and progressive disorder that mainly affects people with sickle cell disease (SCD). Herein, we aimed to search for a better understanding of markers that can act as risk factors for ... ...

Abstract	Purpose: Osteonecrosis of the femoral head (ONFH) is a degenerative and progressive disorder that mainly affects people with sickle cell disease (SCD). Herein, we aimed to search for a better understanding of markers that can act as risk factors for ONFH in patients with SCD. Methods: We conducted a retrospective study including 510 SCD patients followed over 23 years. Patients were divided into the ONFH group and the no-ONHF control group. Univariate and multivariate logistic regression analyses were performed to identify risk factors. Results: Among 510 SCD patients, 41(8%) were diagnosed with ONFH at a mean age of 167 months ± 64 (72-288). The cumulative incidence of ONHF increased from 2.3% at ten years to 18.3% at 20 years of age. The radiological grade 3 ONHF was predominant. No significant differences in sex, age at diagnosis of SCD, and Hb genotype were found between groups. The patient age and the time since diagnosis of SCD were statistically higher in patients with ONHF in univariate and multivariate analysis. ONHF was also associated with higher creatinine level (p = 0.001) lower LDH level (p = 0.006), and higher number of vaso-occlusive crisis (VOC)/patient/year (p < 0.001). The cumulative incidence of ONHF in patients having more than 3 VOC/year was significantly higher (43% versus 18.9% at 20 years, p < 0.001). In addition, infections, gallstones, growth delay, delayed initiation of hydroxyurea, and a higher transfusion rate were significantly associated with ONFH. Conclusion: These findings confirm that ONFH is closely related to the age, severity, and duration of SCD. Better management of this disease prevents acute and chronic complications, and early screening of the ONFH as soon as the first signs of the severity of the disease are detected provides a better functional prognosis.
MeSH term(s)	Humans ; Child ; Retrospective Studies ; Incidence ; Femur Head ; Volatile Organic Compounds ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/epidemiology ; Femur Head Necrosis/etiology ; Femur Head Necrosis/complications ; Risk Factors
Chemical Substances	Volatile Organic Compounds
Language	English
Publishing date	2023-07-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	80384-4
ISSN	1432-5195 ; 0341-2695
ISSN (online)	1432-5195
ISSN	0341-2695
DOI	10.1007/s00264-023-05886-8
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