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Article ; Online: Complete genome sequence of Streptomyces sp. HSG2 from rhizosphere soil of mangrove in Qingmei Gang, Sanya.

Pei, Shengxiang / Niu, Siwen / Xie, Fuquan / Zhang, Shuang / Wang, Wenjing / Zhang, Gaiyun

2021 Volume 203, Issue 6, Page(s) 3519–3524

Abstract: ... Gang, Sanya. The complete genome sequence of the strain HSG2 was obtained using PacBio Sequel HGAP.4 ...

Abstract	Streptomyces sp. HSG2 was isolated from rhizosphere soil of a mangrove forest sample at Qingmei Gang, Sanya. The complete genome sequence of the strain HSG2 was obtained using PacBio Sequel HGAP.4 and comprised of 5,282,528 base pairs with a 71.9 mol% G + C content, 4504 protein-coding genes, and 71 RNAs. An in-silico analysis confirmed that genes associated with polysaccharide hydrolyzation, hydrocarbon degradation, and aerobic denitrification were presented in the genome. We also identified 24 natural product biosynthetic gene clusters for secondary metabolites, including those for streptobactin and nystatin A1. The complete genome sequence indicated that Streptomyces sp. HSG2 will provide insight into the biosynthesis and regulatory mechanisms for its secondary metabolites, and propose a potential use in biotechnological and novel bioactive natural product biosynthetic applications.
MeSH term(s)	Genome, Bacterial/genetics ; Phylogeny ; Rhizosphere ; Sequence Analysis, DNA ; Soil Microbiology ; Streptomyces/genetics ; Wetlands
Language	English
Publishing date	2021-05-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	124824-8
ISSN	1432-072X ; 0302-8933
ISSN (online)	1432-072X
ISSN	0302-8933
DOI	10.1007/s00203-021-02339-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Complete genome sequence of Streptomyces sp. HSG2 from rhizosphere soil of mangrove in Qingmei Gang, Sanya

Pei, Shengxiang / Niu, Siwen / Xie, Fuquan / Zhang, Shuang / Wang, Wenjing / Zhang, Gaiyun

Archives of microbiology. 2021 Aug., v. 203, no. 6

2021

Abstract: ... Gang, Sanya. The complete genome sequence of the strain HSG2 was obtained using PacBio Sequel HGAP.4 ...

Abstract	Streptomyces sp. HSG2 was isolated from rhizosphere soil of a mangrove forest sample at Qingmei Gang, Sanya. The complete genome sequence of the strain HSG2 was obtained using PacBio Sequel HGAP.4 and comprised of 5,282,528 base pairs with a 71.9 mol% G + C content, 4504 protein-coding genes, and 71 RNAs. An in-silico analysis confirmed that genes associated with polysaccharide hydrolyzation, hydrocarbon degradation, and aerobic denitrification were presented in the genome. We also identified 24 natural product biosynthetic gene clusters for secondary metabolites, including those for streptobactin and nystatin A1. The complete genome sequence indicated that Streptomyces sp. HSG2 will provide insight into the biosynthesis and regulatory mechanisms for its secondary metabolites, and propose a potential use in biotechnological and novel bioactive natural product biosynthetic applications.
Keywords	Streptomyces ; biosynthesis ; computer simulation ; denitrification ; mangrove forests ; microbiology ; nucleotide sequences ; nystatin ; polysaccharides ; rhizosphere ; secondary metabolites ; soil
Language	English
Dates of publication	2021-08
Size	p. 3519-3524.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	124824-8
ISSN	1432-072X ; 0302-8933
ISSN (online)	1432-072X
ISSN	0302-8933
DOI	10.1007/s00203-021-02339-x
Database	NAL-Catalogue (AGRICOLA)

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Article: [Textural research on "Shidachuan" and "Shijianchuan" in "Ben Cao Gang Mu Shi Yi" (a supplement to the compendium of materia medica)].

Xie, Z W

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

2000 Volume 25, Issue 1, Page(s) 49–51

Abstract: ... and investigation of therapeutic effects.: Results: In "Ben Cao Gang Mu" (the Compendium ... originally recorded in "Ben Cao Gang Mu Shi Yi" (A Supplement to the Compendium of Materia Medica) should be ...

Abstract	Objective: To investigate the historical origins of folk herbal medicines "Shidachuan" and "Shijianchuan" Method: The origins of "Shidachuan" and "Shijianchuan" were confirmed by textural research and investigation of therapeutic effects. Results: In "Ben Cao Gang Mu" (the Compendium of Materia Medica) "Shidachuan" was not recorded, and "Shijianchuan" was listed only as a medicine of "nomination without use", with the habitat and morphology being blank. Conclusion: The "Shidachuan" which was originally recorded in "Ben Cao Gang Mu Shi Yi" (A Supplement to the Compendium of Materia Medica) should be "Longyacao" (Agrimonia pilosa) of Rosaceae family. "Shijianchuan" should be "Guizhencao" (Bidens bipinata) of Compositae family instead of "Huashuweicao" (Salvia chinensis) of Labiatae family. The herbal medicine recorded as "shijianchuan" in "Chinese Pharmacopoeia" is the very species of Salvia chinensis, which is considered as a new rising species of "Shijianchuan".
MeSH term(s)	Agrimonia/anatomy & histology ; Agrimonia/classification ; Antineoplastic Agents, Phytogenic/history ; Asteraceae/anatomy & histology ; Bidens/anatomy & histology ; China ; Drugs, Chinese Herbal/history ; History, Ancient ; Salvia/anatomy & histology
Chemical Substances	Antineoplastic Agents, Phytogenic ; Drugs, Chinese Herbal
Language	Chinese
Publishing date	2000-01
Publishing country	China
Document type	English Abstract ; Historical Article ; Journal Article
ZDB-ID	1004649-5
ISSN	1001-5302 ; 0254-0029
ISSN	1001-5302 ; 0254-0029
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Conference proceedings: Interne und externe Schrittmacher im Parkinson-Gang: Nucl. subthalamicus-Stimulation und visueller Einfluss

Schubert, M / Faist, M / Xie, J / Berger, W / Prokop, T / Pollak, P / Lücking, CH

Klinische Neurophysiologie

2003

Abstract: ... dieser Ursachen. Unsere Untersuchungen zeigen das Ausmaß des visuellen Einflusses im Gang des Parkinson-Patienten ... der gesteigerten visuellen Abhängigkeit und eine Wiederherstellung einer im Gang des Unbehandelten in auffälliger ...

Event/congress	Deutsche Gesellschaft für Klinische Neurophysiologie und funktionelle Bildgebung zusammen mit der Schweizerischen Gesellschaft für Klinische Neurophysiologie, Freiburg, 2003
Abstract	Patienten mit Morbus Parkinson sind in der Bewegungskontrolle in besonderem Maß auf visuelle Information angewiesen. Diese frühe klinische Beobachtung wurde in experimentellen Untersuchungen bestätigt. Im klinischen Alltag finden sich vielfältige Beispiele für die besondere Bedeutung des Sehens bei Morbus Parkinson; so kann eine Markierung auf dem Untergrund sowohl Starthilfe als auch Schwelle und unüberwindbares Hindernis sein. Die neurophysiologische Ursache dieses Phänomens wie auch der damit zusammenhängenden Hypokinese ist nach wie vor nicht geklärt. Beschrieben wurden neben einer zentralen Afferenzstörung eine Störung der Auslösung adäquater Bewegungsprogramme oder -Synergien oder eine Kombination dieser Ursachen. Unsere Untersuchungen zeigen das Ausmaß des visuellen Einflusses im Gang des Parkinson-Patienten und weisen auf prägnante Unterschiede im Vergleich mit einem gesunden Kontroll-Kollektiv hin. Messungen auf dem Laufband mit spezieller optischer Stimulation durch ein Fließmuster ergaben Hinweise auf die Art der Störung, die zur besonderen Abhängigkeit von visueller Information führt. Die Ergebnisse bestätigen, wie von Morris und Mitarb. bereits beschrieben, eine gestörte Modulation der Schrittlänge. Die Schrittfrequenz blieb im wesentlichen stabil. Bei einem Vergleich mit Patienten mit elektrischer Dauerstimulation nach Implantation im Nucl. subthalamicus fanden wir eine deutliche Verbesserung der Gehfähigkeit mit einer weitgehenden Normalisierung der Schrittparameter. Ferner zeigte sich unter Stimulation eine Normalisierung der gesteigerten visuellen Abhängigkeit und eine Wiederherstellung einer im Gang des Unbehandelten in auffälliger Weise fehlenden Adaptierungsfähigkeit. Diese blieb auch nach Unterbrechung der elektrischen Tiefenhirn-Stimulation erhalten, und die Abhängigkeit von visuellen Stimuli erreichte bei den implantierten Patienten nach Unterbrechung der Stimulation nicht das Ausmaß, das bei nicht implantierten Patienten besteht. Kombinierte Behandlung mit L-DOPA und elektrischer Nucl. subthalamicus-Stimulation wirkte additiv, was im Vergleich mit Gesunden sogar zu vermindertem Ansprechen auf visuelle Stimuli führte. Diese Ergebnisse werden im Hinblick auf die Bedeutung der Nucl. subthalamicus-Stimulation für die Motorkontrolle beim Gehen und hinsichtlich Schlussfolgerungen für die zugrundeliegende neurophysiologische Störung diskutiert.
Language	German
Publishing date	2003-09-18
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	80107-0
ISSN	1439-4081 ; 1434-0275 ; 0012-7590
ISSN (online)	1439-4081
ISSN	1434-0275 ; 0012-7590
DOI	10.1055/s-2003-816537
Database	Thieme publisher's database

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Zs.A 668: Show issues

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Article ; Online: A novel Monte Carlo simulation procedure for modelling COVID-19 spread over time.

Xie, Gang

Scientific reports

2020 Volume 10, Issue 1, Page(s) 13120

Abstract: The coronavirus disease 2019 (COVID-19) has now spread throughout most countries in the world causing heavy life losses and damaging social-economic impacts. Following a stochastic point process modelling approach, a Monte Carlo simulation model was ... ...

Abstract	The coronavirus disease 2019 (COVID-19) has now spread throughout most countries in the world causing heavy life losses and damaging social-economic impacts. Following a stochastic point process modelling approach, a Monte Carlo simulation model was developed to represent the COVID-19 spread dynamics. First, we examined various expected performances (theoretical properties) of the simulation model assuming a number of arbitrarily defined scenarios. Simulation studies were then performed on the real COVID-19 data reported (over the period of 1 March to 1 May) for Australia and United Kingdom (UK). Given the initial number of COVID-19 infection active cases were around 10 for both countries, the model estimated that the number of active cases would peak around 29 March in Australia (≈ 1,700 cases) and around 22 April in UK (≈ 22,860 cases); ultimately the total confirmed cases could sum to 6,790 for Australia in about 75 days and 206,480 for UK in about 105 days. The results of the estimated COVID-19 reproduction numbers were consistent with what was reported in the literature. This simulation model was considered an effective and adaptable decision making/what-if analysis tool in battling COVID-19 in the immediate need, and for modelling any other infectious diseases in the future.
MeSH term(s)	Australia/epidemiology ; Betacoronavirus/isolation & purification ; Betacoronavirus/physiology ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/pathology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Humans ; Monte Carlo Method ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; SARS-CoV-2 ; United Kingdom/epidemiology
Keywords	covid19
Language	English
Publishing date	2020-08-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-70091-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Metabolomic insights into the browning inhibition of fresh-cut apple by hydrogen sulfide.

Chen, Chen / Xie, Jiani / Gang, Jie / Wang, Mingyu / Wu, Ke / Jiang, Aili

Food chemistry

2024 Volume 447, Page(s) 139005

Abstract: Hydrogen sulfide ( ... ...

Abstract	Hydrogen sulfide (H
MeSH term(s)	Malus/chemistry ; Hydrogen Sulfide ; Amino Acids/pharmacology ; Lipids/pharmacology ; Pentanols ; Hemiterpenes
Chemical Substances	Hydrogen Sulfide (YY9FVM7NSN) ; prenol (55MY0HM445) ; Amino Acids ; Lipids ; Pentanols ; Hemiterpenes
Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2024.139005
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A novel Monte Carlo simulation procedure for modelling COVID-19 spread over time

Gang Xie

Scientific Reports, Vol 10, Iss 1, Pp 1-

2020 Volume 9

Abstract: Abstract The coronavirus disease 2019 (COVID-19) has now spread throughout most countries in the world causing heavy life losses and damaging social-economic impacts. Following a stochastic point process modelling approach, a Monte Carlo simulation model ...

Abstract	Abstract The coronavirus disease 2019 (COVID-19) has now spread throughout most countries in the world causing heavy life losses and damaging social-economic impacts. Following a stochastic point process modelling approach, a Monte Carlo simulation model was developed to represent the COVID-19 spread dynamics. First, we examined various expected performances (theoretical properties) of the simulation model assuming a number of arbitrarily defined scenarios. Simulation studies were then performed on the real COVID-19 data reported (over the period of 1 March to 1 May) for Australia and United Kingdom (UK). Given the initial number of COVID-19 infection active cases were around 10 for both countries, the model estimated that the number of active cases would peak around 29 March in Australia (≈ 1,700 cases) and around 22 April in UK (≈ 22,860 cases); ultimately the total confirmed cases could sum to 6,790 for Australia in about 75 days and 206,480 for UK in about 105 days. The results of the estimated COVID-19 reproduction numbers were consistent with what was reported in the literature. This simulation model was considered an effective and adaptable decision making/what-if analysis tool in battling COVID-19 in the immediate need, and for modelling any other infectious diseases in the future.
Keywords	Medicine ; R ; Science ; Q ; covid19
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Thiopyran-Fused Mono and Double Helicenes with Low Band Gaps via Simultaneous Ring Expansion and 6-

Zhou, Zhanglang / Xie, Yujie / Liu, Si / Chen, Weinan / Zhou, Gang

Organic letters

2024 Volume 26, Issue 15, Page(s) 3075–3080

Abstract: Mono and double helicenes ( ...

Abstract	Mono and double helicenes (
Language	English
Publishing date	2024-03-29
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.4c00686
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cathepsin B Responsive Peptide-Purpurin Conjugates Assembly-Initiated in Situ Self-Aggregation for Cancer Sonotheranostics.

Dai, Qixuan / Xie, Lisi / Ren, En / Liu, Gang

Nano letters

2024 Volume 24, Issue 3, Page(s) 950–957

Abstract: Sonodynamic therapy (SDT) was hampered by the sonosensitizers with low bioavailability, tumor accumulation, and therapeutic efficiency. In situ responsive sonosensitizer self-assembly strategy may provide a promising route for cancer sonotheranositics. ... ...

Abstract	Sonodynamic therapy (SDT) was hampered by the sonosensitizers with low bioavailability, tumor accumulation, and therapeutic efficiency. In situ responsive sonosensitizer self-assembly strategy may provide a promising route for cancer sonotheranositics. Herein, an intelligent sonotheranostic peptide-purpurin conjugate (P18-P) is developed that can self-assemble into supramolecular structures via self-aggregation triggered by rich enzyme cathepsin B (CTSB). After intravenous injection, the versatile probe could achieve deep tissue penetration because of the penetration sequence of P18-P. More importantly, CTSB-triggered self-assembly strongly prolonged retention time, amplified photoacoustic imaging signal for sensitive CTSB detection, and boosted reactive oxygen species for advanced SDT, evoking specific CTSB responsive sonotheranostics. This peptide-purpurin conjugate may serve as an efficient sonotheranostic platform for the early diagnosis of CTSB activity and effective cancer therapy.
MeSH term(s)	Humans ; Cathepsin B ; Ultrasonic Therapy/methods ; Neoplasms/drug therapy ; Peptides/therapeutic use ; Reactive Oxygen Species ; Cell Line, Tumor ; Nanoparticles/chemistry
Chemical Substances	Cathepsin B (EC 3.4.22.1) ; Peptides ; Reactive Oxygen Species
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Journal Article
ISSN	1530-6992
ISSN (online)	1530-6992
DOI	10.1021/acs.nanolett.3c04371
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Size-Specific Infrared Spectroscopy of Neutral Hydrated Clusters Based on a Vacuum Ultraviolet Free Electron Laser.

Li, Gang / Xie, Hua / Jiang, Ling

The journal of physical chemistry letters

2024 , Page(s) 4806–4814

Abstract: Spectroscopic study of neutral hydrated clusters provides microscopic insights into the local structures and dynamics of complex systems but is very challenging because of the difficulty in size discrimination. Recently, we developed infrared (IR) ... ...

Abstract	Spectroscopic study of neutral hydrated clusters provides microscopic insights into the local structures and dynamics of complex systems but is very challenging because of the difficulty in size discrimination. Recently, we developed infrared (IR) spectroscopy based on threshold ionization using a tunable vacuum ultraviolet free electron laser (VUV-FEL). This experimental method allows for size-specific IR spectroscopic measurement of numerous neutral clusters without confinement, such as messenger tags, ultraviolet chromophores, and host matrix. This Perspective aims to highlight the latest advances in VUV-FEL-based IR spectroscopic studies on the confinement-free neutral amine-water, sulfur dioxide-water, and metal-water clusters. Fruitful collaborations with high-level quantum chemical calculations are reviewed. Future research directions with relevance to the atmosphere, biology, and catalysis are proposed.
Language	English
Publishing date	2024-04-26
Publishing country	United States
Document type	Journal Article ; Review
ISSN	1948-7185
ISSN (online)	1948-7185
DOI	10.1021/acs.jpclett.4c00896
Database	MEDical Literature Analysis and Retrieval System OnLINE

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