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  1. Article ; Online: Identification of nitrate sources in the Jing River using dual stable isotopes, Northwest China.

    Hu, Jing / Pan, Mengyan / Han, Tianhao / Zhuang, Zhi / Cao, Yunning / Yang, Kaili / Li, Yuliang / Liu, Weiguo

    Environmental science and pollution research international

    2021  Volume 28, Issue 48, Page(s) 68633–68641

    Abstract: ... Nitrate ( ... ...

    Abstract Nitrate (NO
    MeSH term(s) Bayes Theorem ; China ; Environmental Monitoring ; Nitrates/analysis ; Nitrogen Isotopes/analysis ; Rivers ; Water Pollutants, Chemical/analysis
    Chemical Substances Nitrates ; Nitrogen Isotopes ; Water Pollutants, Chemical
    Language English
    Publishing date 2021-07-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-15380-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correction: Comparative effectiveness of aerobic exercise versus Yi Jin Jing on ovarian function in young overweight/obese women with polycystic ovary syndrome: study protocol for a randomized controlled trial.

    Zhao, Jing / Ketlhoafetse, Antonnette / Liu, Xiangyun / Cao, Yang

    Trials

    2022  Volume 23, Issue 1, Page(s) 564

    Language English
    Publishing date 2022-07-15
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-022-06547-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparative effectiveness of aerobic exercise versus Yi Jin Jing on ovarian function in young overweight/obese women with polycystic ovary syndrome: study protocol for a randomized controlled trial.

    Zhao, Jing / Ketlhoafetse, Antonnette / Liu, Xiangyun / Cao, Yang

    Trials

    2022  Volume 23, Issue 1, Page(s) 459

    Abstract: ... an important solution used to manage PCOS, due to its multiple benefits. Yi Jin Jing is an important component ... on the benign effects of Yi Jin Jing on PCOS. The primary purpose of this protocol is to assess ... the effectiveness of aerobic exercise versus Yi Jin Jing, on the management of ovarian function in young overweight ...

    Abstract Background: Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disease among women of childbearing age, characterized by androgen excess and ovarian dysfunction. Aerobic exercise is an important solution used to manage PCOS, due to its multiple benefits. Yi Jin Jing is an important component of traditional Chinese exercise (TCE), based on the root of traditional Chinese medicine theory (TCM), which focuses on keeping the body as a whole in a harmonious state. However, to date there is no literature on the benign effects of Yi Jin Jing on PCOS. The primary purpose of this protocol is to assess the effectiveness of aerobic exercise versus Yi Jin Jing, on the management of ovarian function in young overweight/obese women with PCOS.
    Methods: The study will conduct a controlled randomized, superiority trial with three-arm parallel groups, recruiting 90 women diagnosed with PCOS, ages between 18 and 35 years, with a body mass index (BMI) ≥ 23 kg/m
    Discussion: This proposed study will be the first randomized clinical trial to evaluate the comparative effectiveness of aerobic exercise versus Yi Jin Jing on the management of ovarian function in young overweight/obese women with PCOS. The results may provide a new evidence-based management strategy for young women with PCOS.
    Trial registration: Chinese Clinical Trial Registry ChiCTR1900022385 . Registered on 9 April 2019.
    MeSH term(s) Adolescent ; Adult ; Anti-Mullerian Hormone ; Exercise ; Female ; Humans ; Obesity/complications ; Obesity/diagnosis ; Obesity/therapy ; Overweight/complications ; Overweight/diagnosis ; Overweight/therapy ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/diagnosis ; Polycystic Ovary Syndrome/therapy ; Randomized Controlled Trials as Topic ; Young Adult
    Chemical Substances Anti-Mullerian Hormone (80497-65-0)
    Language English
    Publishing date 2022-06-03
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-022-06377-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparative effectiveness of aerobic exercise versus Yi Jin Jing on ovarian function in young overweight/obese women with polycystic ovary syndrome

    Jing Zhao / Antonnette Ketlhoafetse / Xiangyun Liu / Yang Cao

    Trials, Vol 23, Iss 1, Pp 1-

    study protocol for a randomized controlled trial

    2022  Volume 8

    Abstract: ... Aerobic exercise is an important solution used to manage PCOS, due to its multiple benefits. Yi Jin Jing is ... is no literature on the benign effects of Yi Jin Jing on PCOS. The primary purpose of this protocol ... is to assess the effectiveness of aerobic exercise versus Yi Jin Jing, on the management of ovarian ...

    Abstract Abstract Background Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disease among women of childbearing age, characterized by androgen excess and ovarian dysfunction. Aerobic exercise is an important solution used to manage PCOS, due to its multiple benefits. Yi Jin Jing is an important component of traditional Chinese exercise (TCE), based on the root of traditional Chinese medicine theory (TCM), which focuses on keeping the body as a whole in a harmonious state. However, to date there is no literature on the benign effects of Yi Jin Jing on PCOS. The primary purpose of this protocol is to assess the effectiveness of aerobic exercise versus Yi Jin Jing, on the management of ovarian function in young overweight/obese women with PCOS. Methods The study will conduct a controlled randomized, superiority trial with three-arm parallel groups, recruiting 90 women diagnosed with PCOS, ages between 18 and 35 years, with a body mass index (BMI) ≥ 23 kg/m2. Women will be randomly assigned to either control group (combined oral contraceptives) or one of the intervention groups (Yi Jin Jing group or aerobic exercise group) with an allocation rate of 1:1:1. After randomization, the intervention will be conducted within a 12-week period. The primary outcome would be anti-Mullerian hormone (AMH) level; the secondary outcomes would be biochemical profiles, ovarian volume, antral follicle count, BMI, menstrual frequency, and homeostasis model assessment of insulin resistance (HOMA-IR). Outcome measures would be collected during baseline and end of treatment. Reporting of the study will follow the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) statement. Discussion This proposed study will be the first randomized clinical trial to evaluate the comparative effectiveness of aerobic exercise versus Yi Jin Jing on the management of ovarian function in young overweight/obese women with PCOS. The results may provide a new evidence-based management strategy for young women with ...
    Keywords Polycystic ovary syndrome ; Aerobic exercise ; Yi Jin Jing ; Traditional chinese exercise ; Medicine (General) ; R5-920
    Subject code 796
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Identification of nitrate sources in the Jing River using dual stable isotopes, Northwest China

    Hu, Jing / Pan, Mengyan / Han, Tianhao / Zhuang, Zhi / Cao, Yunning / Yang, Kaili / Li, Yuliang / Liu, Weiguo

    Environ Sci Pollut Res. 2021 Dec., v. 28, no. 48 p.68633-68641

    2021  

    Abstract: ... so identifying the sources and transformations of NO₃⁻ is the basis for improving water quality. Since the Jing ... surface water samples from the Shaanxi section of the Jing River during the dry season. The potential sources ...

    Abstract Nitrate (NO₃⁻) contamination has become a dominant international problem in the aquatic environment, so identifying the sources and transformations of NO₃⁻ is the basis for improving water quality. Since the Jing River is the largest tributary of the Wei River, to understand its water quality, this study collected surface water samples from the Shaanxi section of the Jing River during the dry season. The potential sources of NO₃⁻ were analyzed by hydrochemical and bi-isotopic methods, and the SIAR model was used to estimate the proportional contribution of each source. Results indicated that NO₃⁻-N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg·L⁻¹, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO₃⁻ (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%. These results help to adopt better nitrogen management measures to meet the national environmental quality standards for surface water.
    Keywords Bayesian theory ; aquatic environment ; dry season ; hydrochemistry ; models ; nitrates ; nitrification ; nitrogen ; pollution ; rivers ; sewage ; soil ; surface water ; total nitrogen ; water quality ; China
    Language English
    Dates of publication 2021-12
    Size p. 68633-68641.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-15380-6
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Compound Analysis of Jing Liqueur and nrf2 Activation by Jing Liqueur—One of the Most Popular Beverages in China

    You-Sheng Cai / Jian Xu / Mosi Chen / Daoqing Wang / Yuejun Yang / Arulmani Manavalan / Xiaohua Wu / Yuancai Liu / Shugeng Cao

    Beverages, Vol 6, Iss 1, p

    2019  Volume 1

    Abstract: The aim of this study is to identify the minor compounds in Jing liqueur, determine ... Jing liqueur that contains Chinese medicine is one of the best-selling liqueurs in China, which is also ... from a concentrated Jing liqueur, with the concentrations of most isolated compounds at micromolar levels ...

    Abstract The aim of this study is to identify the minor compounds in Jing liqueur, determine the concentration of metals, amino acids, and polysaccharides, and evaluate their Nrf2 activity and cytotoxicity. Jing liqueur that contains Chinese medicine is one of the best-selling liqueurs in China, which is also marketed in the United States. Totally, we have isolated 189 minor compounds including one new molecule ( 7 ) from a concentrated Jing liqueur, with the concentrations of most isolated compounds at micromolar levels. The structures of all these compounds were determined by using MS and NMR (1D and 2D) or by comparison of their chemical and physical data with reported values in the literatures. Besides, the concentrations of iron (0.52 mg/L), zinc (0.21 mg/L), calcium (11.0 mg/L), L -proline (2.33 mg/L), L -arginine (1.73 mg/L), total amino acids (9.84 mg/L), and total polysaccharides (337.4 mg/L) were determined. Jing liqueur, the five fractions and most of the compounds isolated from Jing liqueur were screened for their activities in the Nrf2-ARE and MTT assays. At 5.2 mg/mL the crude enhanced the Nrf2 activity. At 80 μg/mL, fraction IV weakly but fraction V strongly activated Nrf2. Among the compounds screened in the Nrf2 assay, eighteen activated Nrf2 at 40 μg/mL and compounds 51 and 126 from fraction V were the most active. The crude, all the five fractions, and Nrf2 activators were not cytotoxic toward HepG2 cells. In conclusion, Jing liqueur contains different classes of compounds including flavonoids, terpenoids, alkaloids, coumarins, cinnamic acid or coumaric acid, and phenyl ethanol (or acetic acid) derivatives, benzoquinone, naphthoquinone, anthraquinones or phenanphrene derivatives, xanthones, chromone, and γ-pyrone derivatives, lignans, other aromatic compounds, and others. Jing liqueur and the eighteen compounds, which were isolated from Jing liqueur, could activate Nrf2 without any cytotoxicity.
    Keywords jing liqueur ; traditional chinese medicine ; compounds ; nmr ; ms ; nrf2-are ; Nutrition. Foods and food supply ; TX341-641 ; Nutritional diseases. Deficiency diseases ; RC620-627
    Subject code 540
    Language English
    Publishing date 2019-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Compound Analysis of Jing Liqueur and nrf2 Activation by Jing Liqueur—One of the Most Popular Beverages in China

    Cai, You-Sheng / Xu, Jian / Chen, Mosi / Wang, Daoqing / Yang, Yuejun / Manavalan, Arulmani / Wu, Xiaohua / Liu, Yuancai / Cao, Shugeng

    Beverages. 2019 Dec. 31, v. 6, no. 1

    2019  

    Abstract: The aim of this study is to identify the minor compounds in Jing liqueur, determine ... Jing liqueur that contains Chinese medicine is one of the best-selling liqueurs in China, which is also ... from a concentrated Jing liqueur, with the concentrations of most isolated compounds at micromolar levels ...

    Abstract The aim of this study is to identify the minor compounds in Jing liqueur, determine the concentration of metals, amino acids, and polysaccharides, and evaluate their Nrf2 activity and cytotoxicity. Jing liqueur that contains Chinese medicine is one of the best-selling liqueurs in China, which is also marketed in the United States. Totally, we have isolated 189 minor compounds including one new molecule (7) from a concentrated Jing liqueur, with the concentrations of most isolated compounds at micromolar levels. The structures of all these compounds were determined by using MS and NMR (1D and 2D) or by comparison of their chemical and physical data with reported values in the literatures. Besides, the concentrations of iron (0.52 mg/L), zinc (0.21 mg/L), calcium (11.0 mg/L), L-proline (2.33 mg/L), L-arginine (1.73 mg/L), total amino acids (9.84 mg/L), and total polysaccharides (337.4 mg/L) were determined. Jing liqueur, the five fractions and most of the compounds isolated from Jing liqueur were screened for their activities in the Nrf2-ARE and MTT assays. At 5.2 mg/mL the crude enhanced the Nrf2 activity. At 80 μg/mL, fraction IV weakly but fraction V strongly activated Nrf2. Among the compounds screened in the Nrf2 assay, eighteen activated Nrf2 at 40 μg/mL and compounds 51 and 126 from fraction V were the most active. The crude, all the five fractions, and Nrf2 activators were not cytotoxic toward HepG2 cells. In conclusion, Jing liqueur contains different classes of compounds including flavonoids, terpenoids, alkaloids, coumarins, cinnamic acid or coumaric acid, and phenyl ethanol (or acetic acid) derivatives, benzoquinone, naphthoquinone, anthraquinones or phenanphrene derivatives, xanthones, chromone, and γ-pyrone derivatives, lignans, other aromatic compounds, and others. Jing liqueur and the eighteen compounds, which were isolated from Jing liqueur, could activate Nrf2 without any cytotoxicity.
    Keywords Oriental traditional medicine ; acetic acid ; anthraquinones ; arginine ; benzoquinones ; calcium ; cinnamic acid ; coumaric acids ; coumarins ; cytotoxicity ; ethanol ; flavonoids ; iron ; lignans ; liqueurs ; naphthoquinones ; polysaccharides ; proline ; terpenoids ; xanthones ; zinc ; China
    Language English
    Dates of publication 2019-1231
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2785444-9
    ISSN 2306-5710
    ISSN 2306-5710
    DOI 10.3390/beverages6010001
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: [A multicenter randomized controlled study of bismuth-containing quadruple therapy followed by Jing-Hua-Wei-Kang in the treatment of patients newly diagnosed with

    Ma, P P / Meng, L N / Wang, M T / Jin, H F / Fan, Y H / Zha, A S / Huo, X H / Chen, D F / Cao, Z Q / Tang, X F / Yang, P / Shi, Z H / Li, T W / Meng, J / Gan, C / Chen, G X / Sha, W H / Du, Q / Li, Y /
    Lyu, B

    Zhonghua yi xue za zhi

    2021  Volume 101, Issue 26, Page(s) 2060–2065

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Amoxicillin/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Bismuth/therapeutic use ; China ; Drug Therapy, Combination ; Dyspepsia/drug therapy ; Female ; Helicobacter Infections/drug therapy ; Helicobacter pylori ; Humans ; Male ; Middle Aged ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents ; Amoxicillin (804826J2HU) ; Bismuth (U015TT5I8H)
    Language Chinese
    Publishing date 2021-07-18
    Publishing country China
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20210305-00563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Inhibitory Effect of Jing-Fang Powder n-Butanol Extract and Its Isolated Fraction D on Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells.

    Rao, Zhili / Cao, Haijuan / Shi, Boyu / Liu, Xiaobo / Luo, Jie / Zeng, Nan

    The Journal of pharmacology and experimental therapeutics

    2019  Volume 370, Issue 1, Page(s) 62–71

    Abstract: The Jing-Fang powder n-butanol extract (JFNE) has anti-inflammatory properties ...

    Abstract The Jing-Fang powder n-butanol extract (JFNE) has anti-inflammatory properties; however, its active ingredient remains unknown. In addition, the mechanism by which JFNE exerts its anti-inflammatory effects on lipopolysaccharide (LPS)-induced inflammation in RAW264.7 cells is yet to be explored. In this study, JFNE was isolated by chromatography to obtain fraction D. We found that pretreatment of LPS-induced RAW264.7 cells with JFNE and fraction D for 3 hours significantly reduced the levels of nitric oxide (NO), interleukin (IL)-1
    MeSH term(s) 1-Butanol/chemistry ; Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Apiaceae/chemistry ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/isolation & purification ; Drugs, Chinese Herbal/pharmacology ; Gene Expression Regulation/drug effects ; Inflammation/drug therapy ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-1beta/genetics ; Interleukin-6/genetics ; Lamiaceae/chemistry ; Lipopolysaccharides/pharmacology ; Mice ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Powders ; Proto-Oncogene Proteins c-akt/metabolism ; RAW 264.7 Cells ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/genetics
    Chemical Substances Anti-Inflammatory Agents ; Drugs, Chinese Herbal ; Interleukin-1beta ; Interleukin-6 ; Lipopolysaccharides ; NF-kappa B ; Powders ; Tumor Necrosis Factor-alpha ; Nitric Oxide (31C4KY9ESH) ; 1-Butanol (8PJ61P6TS3) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2019-05-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3106-9
    ISSN 1521-0103 ; 0022-3565
    ISSN (online) 1521-0103
    ISSN 0022-3565
    DOI 10.1124/jpet.118.255893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Evaluation of the adjunctive effect of Xing Nao Jing Injection for viral encephalitis: A systematic review and meta-analysis of randomized controlled trials.

    Cao, Hui-Juan / Liang, Shi-Bing / Zhou, Wei / Wu, Jia-Rui / Zhang, Cheng-Liang

    Medicine

    2019  Volume 98, Issue 15, Page(s) e15181

    Abstract: Background: To systematically evaluate the effect and safety of Xing Nao Jing (XNJ) injection ...

    Abstract Background: To systematically evaluate the effect and safety of Xing Nao Jing (XNJ) injection as an add-on treatment on the treatment for viral encephalitis (VE).
    Methods: Trials assessing the adjunctive effectiveness of XNJ injection for VE were searched from 4 electronic databases from inception to October 31, 2018. Two authors independently extracted data and assessed risk of bias. Statistical analyses were performed using RevMan 5.3 software. Meta-analysis and additional analysis were conducted if data permitted. Trial Sequential Analysis and Grading of Recommendations Assessment, Development and Evaluation (GRADE) were also performed.
    Results: This review involved 23 trials and 1757 participants, all trials were assessed as having unclear risk of bias. Results from 5 meta-analyses, 13 subgroup meta-analyses, and the single studies showed that based on conventional therapy XNJ injection (0.4-0.6 mL/kg daily for children, 20 mL/day for adults) may have better effect on increasing the numbers of cured patients and decreasing the time of recovery of main symptoms for patients with viral encephalitis. Patients used combination of XNJ injection and conventional therapy had higher cured rate (risk ratio 1.61, 95% confidence interval 1.45-1.80, 19 trials, 1456 participants) and less mortality rate (risk ratio 0.26, 95% confidence interval 0.10-0.71, 9 trials, 595 participants). The average difference of time for fever, conscious, or convulsive recovery was average 2 hours shorter in combination group than in control. No difference was found between children and adults according to the subgroup analysis. Safety of the XNJ injection was failed to evaluate due to the insufficient evidence in this review.
    Conclusions: This review found "very low" quality evidence which showed the potential effectiveness of combination of XNJ injection and conventional therapies for VE. Considering the TSA results, conclusion could only be draw on effectiveness of the XNJ injection as add-on treatment for VE patients on increasing the cured rate. Firm conclusion on other outcome measures for effectiveness assessment or safety of XNJ injection could not be draw according to this review due to the insufficient evidence.
    MeSH term(s) Central Nervous System Agents/administration & dosage ; Central Nervous System Agents/adverse effects ; Chemotherapy, Adjuvant/adverse effects ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/adverse effects ; Encephalitis, Viral/drug therapy ; Humans ; Injections ; Randomized Controlled Trials as Topic
    Chemical Substances Central Nervous System Agents ; Drugs, Chinese Herbal ; xingnaojing
    Language English
    Publishing date 2019-05-06
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000015181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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