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  1. Book ; Online: Training modules on Hepatitis B and C screening, diagnosis and treatment

    World Health Organization. Regional Office for South-East Asia

    2020  

    Keywords Hepatitis B virus ; Hepatitis C
    Language English
    Publisher World Health Organization. Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: First consultation of the Regional Expert Panel for verification of Hepatitis B Control in the South-East Asia Region New Delhi, India, 28–29 May 2019

    World Health Organization. Regional Office for South-East Asia

    2020  

    Keywords Hepatitis B virus
    Language English
    Publisher World Health Organization. Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Online: Guidelines for verification of achievement of hepatitis B control target through immunization in the WHO South-East Asia Region

    World Health Organization. Regional Office for South-East Asia

    2019  

    Keywords Immunization
    Language English
    Publisher World Health Organization. Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  4. Book ; Online: Regional dissemination workshop on Guidelines for HIV and Hepatitis B & C, New Delhi, India, 09 - 11 May 2018

    World Health Organization. Regional Office for South-East Asia

    2018  

    Keywords HIV
    Language English
    Publisher World Health Organization. Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  5. Book ; Online: Post-Introduction Evaluation (PIE) of Pentavalent (DTP-Hib-Hepatitis B) and Inactivated Polio Vaccines

    World Health Organization. Regional Office for South-East Asia

    Report of the joint national/international mission Democratic People’s Republic of Korea, 8–17 October 2016

    2017  

    Keywords Vaccination ; Poliomyelitis
    Language English
    Publisher World Health Organization. Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Triple neurectomy following Lichtenstein repair of inguinal hernia.

    Jíšová, B / Hladík, P / East, B

    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti

    2024  Volume 102, Issue 9, Page(s) 363–365

    Abstract: Introduction: Chronic pain is a distressing complication that can occur after inguinal hernia repair, affecting between 5% and 20% of patients as reported in literature. There are several reasons for chronic pain, including peripheral nerve irritation ... ...

    Title translation Trineurektomie po plastice tříselné kýly dle Lichtensteina.
    Abstract Introduction: Chronic pain is a distressing complication that can occur after inguinal hernia repair, affecting between 5% and 20% of patients as reported in literature. There are several reasons for chronic pain, including peripheral nerve irritation caused by surgical mesh or stitches. Preoperative pain is a risk factor for chronic pain.
    Case report: We present the case of a 59-year-old man who experienced chronic inguinal pain following Lichtenstein hernia repair. Conservative therapy was ineffective, and he subsequently underwent triple neurectomy without removal of the original polypropylene mesh. The patient experienced significant pain relief immediately after the surgery. There was no reported pain 1 month and 1 year post-surgery.
    Conclusion: The management of patients with chronic pain following hernia repair should be comprehensive and, ideally, centralized. Conservative procedures should be attempted first, but neurectomy and mesh removal may be necessary in cases where conservative measures are unsuccessful.
    MeSH term(s) Humans ; Male ; Middle Aged ; Chronic Pain/etiology ; Chronic Pain/surgery ; Denervation ; Hernia, Inguinal/surgery ; Hernia, Inguinal/complications ; Herniorrhaphy/adverse effects ; Herniorrhaphy/methods ; Pain, Postoperative/etiology ; Pain, Postoperative/surgery ; Surgical Mesh/adverse effects
    Language English
    Publishing date 2024-03-13
    Publishing country Czech Republic
    Document type Case Reports ; Journal Article
    ZDB-ID 414059-x
    ISSN 1805-4579 ; 0035-9351
    ISSN (online) 1805-4579
    ISSN 0035-9351
    DOI 10.33699/PIS.2023.102.9.363-365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 224: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online: Prevention of Hepatitis B in India

    World Health Organization. Regional Office for South-East Asia

    an overview

    2002  

    Keywords IMMUNIZATION
    Language English
    Publisher WHO Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene.

    Johnson, Matthew P / Brennecke, Shaun P / East, Christine E / Göring, Harald H H / Kent, Jack W / Dyer, Thomas D / Said, Joanne M / Roten, Linda T / Iversen, Ann-Charlotte / Abraham, Lawrence J / Heinonen, Seppo / Kajantie, Eero / Kere, Juha / Kivinen, Katja / Pouta, Anneli / Laivuori, Hannele / Austgulen, Rigmor / Blangero, John / Moses, Eric K

    PloS one

    2012  Volume 7, Issue 3, Page(s) e33666

    Abstract: ... from the 3' terminus of the Inhibin, beta B (INHBB) gene on 2q14.2. They are in linkage disequilibrium (LD ...

    Abstract Elucidating the genetic architecture of preeclampsia is a major goal in obstetric medicine. We have performed a genome-wide association study (GWAS) for preeclampsia in unrelated Australian individuals of Caucasian ancestry using the Illumina OmniExpress-12 BeadChip to successfully genotype 648,175 SNPs in 538 preeclampsia cases and 540 normal pregnancy controls. Two SNP associations (rs7579169, p = 3.58×10(-7), OR = 1.57; rs12711941, p = 4.26×10(-7), OR = 1.56) satisfied our genome-wide significance threshold (modified Bonferroni p<5.11×10(-7)). These SNPs reside in an intergenic region less than 15 kb downstream from the 3' terminus of the Inhibin, beta B (INHBB) gene on 2q14.2. They are in linkage disequilibrium (LD) with each other (r(2) = 0.92), but not (r(2)<0.80) with any other genotyped SNP ±250 kb. DNA re-sequencing in and around the INHBB structural gene identified an additional 25 variants. Of the 21 variants that we successfully genotyped back in the case-control cohort the most significant association observed was for a third intergenic SNP (rs7576192, p = 1.48×10(-7), OR = 1.59) in strong LD with the two significant GWAS SNPs (r(2)>0.92). We attempted to provide evidence of a putative regulatory role for these SNPs using bioinformatic analyses and found that they all reside within regions of low sequence conservation and/or low complexity, suggesting functional importance is low. We also explored the mRNA expression in decidua of genes ±500 kb of INHBB and found a nominally significant correlation between a transcript encoded by the EPB41L5 gene, ∼250 kb centromeric to INHBB, and preeclampsia (p = 0.03). We were unable to replicate the associations shown by the significant GWAS SNPs in case-control cohorts from Norway and Finland, leading us to conclude that it is more likely that these SNPs are in LD with as yet unidentified causal variant(s).
    MeSH term(s) Australia ; Chromosomes, Human, Pair 2/genetics ; Cohort Studies ; Computational Biology ; Female ; Finland ; Gene Expression Regulation ; Genetic Loci/genetics ; Genetic Predisposition to Disease ; Genome, Human/genetics ; Genome-Wide Association Study ; Humans ; Inhibin-beta Subunits/genetics ; Inhibin-beta Subunits/metabolism ; Norway ; Polymorphism, Single Nucleotide/genetics ; Pre-Eclampsia/genetics ; Pregnancy ; Reproducibility of Results ; Risk Factors ; Sequence Analysis, DNA
    Chemical Substances INHBB protein, human ; Inhibin-beta Subunits (93443-12-0)
    Language English
    Publishing date 2012-03-14
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0033666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  9. Book ; Online: Prevention of Hepatitis B in India

    World Health Organization, Regional Office for South-East Asia

    an overview

    2002  

    Keywords IMMUNIZATION
    Language English
    Publisher WHO Regional Office for South-East Asia
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

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  10. Article: OP004. A SNP associated with susceptibility to preeclampsia near the inhibin, beta B gene, is also associated with cardiovascular disease risk traits.

    Løset, Mari / Johnson, Matthew P / Melton, Phillip E / Ang, Wei / Marsh, Julie / Huang, Rae-Chi / Mori, Trevor / Beilin, Lawrence / Pennell, Craig / Roten, Linda T / Iversen, Ann-Charlotte / Austgulen, Rigmor / East, Christine E / Blangero, John / Brennecke, Shaun P / Moses, Eric K

    Pregnancy hypertension

    2013  Volume 3, Issue 2, Page(s) 63

    Abstract: ... PE susceptibility (odds ratio 1.57). This SNP resides near the Inhibin, beta B (INHBB) gene ...

    Abstract Introduction: It is well established that preeclampsia (PE) increases later life cardiovascular disease (CVD) risk. Consequently, PE has started to gain a role as an early screening criterion for CVD. PE and CVD share several risk factors, pathological features and metabolic abnormalities. These common antecedents have drawn attention to the likelihood of shared genetic susceptibility.
    Objectives: Results from our previous PE GWAS identified a significant association with the rs7579169 SNP and maternal PE susceptibility (odds ratio 1.57). This SNP resides near the Inhibin, beta B (INHBB) gene on chromosome 2q14. Therefore, this study sought to interrogate this PE susceptibility SNP against several CVD risk traits in an effort to highlight additional empirical evidence of likely shared PE/CVD genetic mechanisms.
    Methods: The rs7579169 SNP was genotyped in a large independent Australian cohort rich in quantitative CVD risk traits; The Western Australian Pregnancy Cohort (Raine) Study. This cohort comprises of fasting blood samples from 1246 mothers and 1461 adolescents (14- and 17-year-old) and clinical parameters pertaining, but not limited, to anthropometric measures of adiposity and lipid-related measures. Genetic association analyses of rs7579169 against the Raine CVD-related risk traits were performed using the software package R. All statistical analyses assumed an additive model of gene action.
    Results: Significant associations (p<0.05) for rs7579169 with CVD-related risk traits were detected, both for the mothers and the adolescents. Specifically, the minor rs7579169-T allele (MAF 0.400) was found to be significantly associated with elevated levels of triglycerides, total and LDL cholesterol, a greater average waist:hip circumference ratio and a greater average hip circumference.
    Conclusion: We have previously identified rs7579169 located near the INHBB gene on chromosome 2q14 to significantly associate with maternal PE susceptibility. We have now demonstrated that this SNP is also significantly associated with several CVD-related risk traits in an independent Caucasian population. We hereby present additional empirical evidence of possible shared genetic risk factors underlying both PE and CVD related traits.
    Language English
    Publishing date 2013-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2584464-7
    ISSN 2210-7797 ; 2210-7789
    ISSN (online) 2210-7797
    ISSN 2210-7789
    DOI 10.1016/j.preghy.2013.04.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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