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  1. Article ; Online: Structural Racism and Pedestrian Safety: Measuring the Association Between Historical Redlining and Contemporary Pedestrian Fatalities Across the United States, 2010‒2019.

    Taylor, Nandi L / Porter, Jamila M / Bryan, Shenee / Harmon, Katherine J / Sandt, Laura S

    American journal of public health

    2023  Volume 113, Issue 4, Page(s) 420–428

    Abstract: Objectives. ...

    Abstract Objectives.
    MeSH term(s) Humans ; United States/epidemiology ; Systemic Racism ; Pedestrians ; Transportation ; Accidents, Traffic
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/AJPH.2022.307192
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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.279: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Arthroscopic Subdeltoid Transfer of the Long Head of the Biceps Tendon to the Conjoint Tendon.

    White, Alex E / Bryan, Matthew R / O'Brien, Stephen J / Taylor, Samuel A

    Arthroscopy techniques

    2023  Volume 12, Issue 12, Page(s) e2313–e2319

    Abstract: Surgical intervention is often recommended for refractory pathology affecting the biceps-labrum complex. Tenodesis of the long head of the biceps tendon (LHBT) is a widely accepted treatment modality; however, the optimal technique remains elusive. ... ...

    Abstract Surgical intervention is often recommended for refractory pathology affecting the biceps-labrum complex. Tenodesis of the long head of the biceps tendon (LHBT) is a widely accepted treatment modality; however, the optimal technique remains elusive. Arthroscopic subdeltoid transfer of the LHBT to the conjoint tendon, as described in this technical note, continues to demonstrate excellent clinical results. Its advantages include soft tissue-to-soft tissue healing, an advantageous biomechanical construct, and comprehensive evaluation and decompression of the LHBT including the extra-articular bicipital tunnel. The primary limitation of this procedure is the perceived learning curve for safe navigation within the subdeltoid space.
    Language English
    Publishing date 2023-11-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2653101-X
    ISSN 2212-6287
    ISSN 2212-6287
    DOI 10.1016/j.eats.2023.07.060
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  3. Article: The Effect of Social Connectedness on Crime: Evidence from the Great Migration.

    Stuart, Bryan A / Taylor, Evan J

    The review of economics and statistics

    2021  Volume 103, Issue 1, Page(s) 18–33

    Abstract: This paper estimates the effect of social connectedness on crime across U.S. cities from 1970 to 2009. Migration networks among African Americans from the South generated variation across destinations in the concentration of migrants from the same birth ... ...

    Abstract This paper estimates the effect of social connectedness on crime across U.S. cities from 1970 to 2009. Migration networks among African Americans from the South generated variation across destinations in the concentration of migrants from the same birth town. Using this novel source of variation, we find that social connectedness considerably reduces murders, rapes, robberies, assaults, burglaries, and motor vehicle thefts, with a one standard deviation increase in social connectedness reducing murders by 21 percent and motor vehicle thefts by 20 percent. Social connectedness especially reduces murders of adolescents and young adults committed during gang and drug activity.
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1483322-0
    ISSN 1530-9142 ; 2329-0560 ; 0034-6535 ; 1553-0027
    ISSN (online) 1530-9142 ; 2329-0560
    ISSN 0034-6535 ; 1553-0027
    DOI 10.1162/rest_a_00860
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  4. Article ; Online: Inspiratory muscle weakness in cardiovascular diseases: Implications for cardiac rehabilitation.

    Smith, Joshua R / Taylor, Bryan J

    Progress in cardiovascular diseases

    2021  Volume 70, Page(s) 49–57

    Abstract: Exercise limitation is a cardinal manifestation of many cardiovascular diseases (CVD) and is associated with poor prognosis. It is increasingly well understood that exercise-based cardiac rehabilitation (CR) is an intervention that portends favorable ... ...

    Abstract Exercise limitation is a cardinal manifestation of many cardiovascular diseases (CVD) and is associated with poor prognosis. It is increasingly well understood that exercise-based cardiac rehabilitation (CR) is an intervention that portends favorable clinical outcomes, including improvements in exercise capacity. The etiology of exercise limitation in CVD is multifactorial but is typically governed by terminal sensations of pain, fatigue, and/or breathlessness. A known but perhaps underestimated complication of CVD that contributes to breathlessness and exercise intolerance in such patients is inspiratory muscle dysfunction. For example, inspiratory muscle dysfunction, which encompasses a loss in muscle mass and/or pressure generating capacity, occurs in up to ~40% of patients with chronic heart failure and is associated with breathlessness, exertional intolerance, and worse survival in this patient population. In this review, we define inspiratory muscle weakness, detail its prevalence in a range of CVDs, and discuss how inspiratory weakness impacts physiological function and clinical outcomes in patients with CVD often referred to CR. We also evaluate the available evidence addressing the effects of exercise-based CR with and without concurrent specific inspiratory muscle training (IMT) on inspiratory muscle function, general physiological function, and clinical outcomes in patients with CVD. Finally, we consider whether the assessment of global respiratory muscle function should become standard as part of the patient intake assessment for phase II CR programs, giving practical guidance on the implementation of such measures as well as IMT as part of phase II CR.
    MeSH term(s) Cardiac Rehabilitation ; Cardiovascular Diseases/diagnosis ; Dyspnea/complications ; Exercise Tolerance/physiology ; Humans ; Muscle Strength/physiology ; Muscle Weakness/diagnosis ; Muscle Weakness/etiology ; Respiratory Muscles/physiology
    Language English
    Publishing date 2021-10-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 209312-1
    ISSN 1873-1740 ; 1532-8643 ; 0033-0620
    ISSN (online) 1873-1740 ; 1532-8643
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2021.10.002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 229: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Caregivers of patients with malignant pleural mesothelioma: who provides care, what care do they provide and what burden do they experience?

    Moore, Adam / Bennett, Bryan / Taylor-Stokes, Gavin / Daumont, Melinda J

    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

    2023  Volume 32, Issue 9, Page(s) 2587–2599

    Abstract: Purpose: There are limited data on the impact of caregiving for patients with malignant pleural mesothelioma (MPM) on the caregiver. We aimed to identify the demographic characteristics of these caregivers, the caregiving activities they perform and how ...

    Abstract Purpose: There are limited data on the impact of caregiving for patients with malignant pleural mesothelioma (MPM) on the caregiver. We aimed to identify the demographic characteristics of these caregivers, the caregiving activities they perform and how caregiving burden impacts their work productivity and overall activity.
    Methods: This cross-sectional study collected data from caregivers of patients with MPM across France, Italy, Spain and the United Kingdom January-June 2019. Caregiver demographics, daily caregiving tasks and the impact of caregiving on physical health was collected via questionnaire. The Zarit Burden Interview (ZBI) was used to assess caregiver burden and the Work Productivity and Activity Impairment questionnaire (WPAI) assessed impairment at work and during daily activities. Analyses were descriptive.
    Results: Overall, 291 caregivers provided data. Caregivers were mostly female (83%), living with the patient (82%) and their partner/spouse (71%). Caregivers provided over five hours of daily emotional/physical support to patients. ZBI scores indicated 74% of caregivers were at risk of developing depression. Employed caregivers had missed 12% of work in the past seven days, with considerable presenteeism (25%) and overall work impairment (33%) observed. Overall, the mean activity impairment was 40%.
    Conclusion: Caregivers provide essential care for those with MPM. We show caregiving for patients with MPM involves a range of burdensome tasks that impact caregivers' emotional health and work reflected in ZBI and WPAI scores. Innovations in the management of MPM must account for how caregivers may be impacted and can be supported to carry out this important role.
    MeSH term(s) Humans ; Female ; Male ; Caregivers/psychology ; Quality of Life/psychology ; Cost of Illness ; Mesothelioma, Malignant ; Cross-Sectional Studies ; Surveys and Questionnaires
    Language English
    Publishing date 2023-04-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1161148-0
    ISSN 1573-2649 ; 0962-9343
    ISSN (online) 1573-2649
    ISSN 0962-9343
    DOI 10.1007/s11136-023-03410-4
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    Zs.A 3796: Show issues Location:
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  6. Article ; Online: Overexpression of T3SS translocation signals in

    Abele, Taylor J / Billman, Zachary P / Harvest, Carissa K / Bryan, Alexia K / Larson, Heather N / Coers, Jörn / Miao, Edward A

    Infection and immunity

    2023  Volume 92, Issue 1, Page(s) e0032923

    Abstract: Engineering pathogens is a useful method for discovering new details of microbial pathogenesis and host defense. However, engineering can result in off-target effects. We previously ... ...

    Abstract Engineering pathogens is a useful method for discovering new details of microbial pathogenesis and host defense. However, engineering can result in off-target effects. We previously engineered
    MeSH term(s) Animals ; Mice ; Salmonella typhimurium ; Virulence ; Type III Secretion Systems/genetics ; Virulence Factors/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism
    Chemical Substances Type III Secretion Systems ; Virulence Factors ; Bacterial Proteins
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/iai.00329-23
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    Zs.A 684: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article ; Online: Metabolic changes and retinal remodeling in Heterozygous CRX mutant cats (CRX

    Occelli, Laurence M / Jones, Bryan W / Cervantes, Taylor J / Petersen-Jones, Simon M

    Experimental eye research

    2023  Volume 235, Page(s) 109630

    Abstract: CRX is a transcription factor essential for normal photoreceptor development and survival. The ... ...

    Abstract CRX is a transcription factor essential for normal photoreceptor development and survival. The CRX
    MeSH term(s) Animals ; Retina/metabolism ; Retinal Cone Photoreceptor Cells/metabolism ; Retinal Degeneration/metabolism ; Leber Congenital Amaurosis/genetics ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism
    Chemical Substances Homeodomain Proteins
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80122-7
    ISSN 1096-0007 ; 0014-4835
    ISSN (online) 1096-0007
    ISSN 0014-4835
    DOI 10.1016/j.exer.2023.109630
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    Zs.A 163: Show issues Location:
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  8. Article ; Online: Proteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed to (±) anatoxin-a.

    Langan, Laura M / Lovin, Lea M / Taylor, Raegyn B / Scarlett, Kendall R / Kevin Chambliss, C / Chatterjee, Saurabh / Scott, J Thad / Brooks, Bryan W

    Environment international

    2024  Volume 185, Page(s) 108514

    Abstract: Anatoxin-a and its analogues are potent neurotoxins produced by several genera of cyanobacteria. Due in part to its high toxicity and potential presence in drinking water, these toxins pose threats to public health, companion animals and the environment. ...

    Abstract Anatoxin-a and its analogues are potent neurotoxins produced by several genera of cyanobacteria. Due in part to its high toxicity and potential presence in drinking water, these toxins pose threats to public health, companion animals and the environment. It primarily exerts toxicity as a cholinergic agonist, with high affinity at neuromuscular junctions, but molecular mechanisms by which it elicits toxicological responses are not fully understood. To advance understanding of this cyanobacteria, proteomic characterization (DIA shotgun proteomics) of two common fish models (zebrafish and fathead minnow) was performed following  (±) anatoxin-a exposure. Specifically, proteome changes were identified and quantified in larval fish exposed for 96 h (0.01-3 mg/L (±) anatoxin-a and caffeine (a methodological positive control) with environmentally relevant treatment levels examined based on environmental exposure distributions of surface water data. Proteomic concentration - response relationships revealed 48 and 29 proteins with concentration - response relationships curves for zebrafish and fathead minnow, respectively. In contrast, the highest number of differentially expressed proteins (DEPs) varied between zebrafish (n = 145) and fathead minnow (n = 300), with only fatheads displaying DEPs at all treatment levels. For both species, genes associated with reproduction were significantly downregulated, with pathways analysis that broadly clustered genes into groups associated with DNA repair mechanisms. Importantly, significant differences in proteome response between the species was also observed, consistent with prior observations of differences in response using both behavioral assays and gene expression, adding further support to model specific differences in organismal sensitivity and/or response. When DEPs were read across from humans to zebrafish, disease ontology enrichment identified diseases associated with cognition and muscle weakness consistent with the prior literature. Our observations highlight limited knowledge of how (±) anatoxin-a, a commonly used synthetic racemate surrogate, elicits responses at a molecular level and advances its toxicological understanding.
    MeSH term(s) Animals ; Humans ; Zebrafish/metabolism ; Proteome/metabolism ; Larva ; Proteomics ; Cyprinidae/metabolism ; Water Pollutants, Chemical/toxicity ; Cyanobacteria Toxins ; Tropanes
    Chemical Substances anatoxin a (80023A73NK) ; Proteome ; Water Pollutants, Chemical ; Cyanobacteria Toxins ; Tropanes
    Language English
    Publishing date 2024-02-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2024.108514
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  9. Article ; Online: Quadriceps Muscle Fatigue Reduces Extension and Flexion Power During Maximal Cycling.

    O'Bryan, Steven J / Taylor, Janet L / D'Amico, Jessica M / Rouffet, David M

    Frontiers in sports and active living

    2022  Volume 3, Page(s) 797288

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2022-01-07
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2021.797288
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  10. Article ; Online: The 2020-2021 Residency Application Cycle: Lessons Learned and Lingering Problems.

    Hammoud, Maya M / Standiford, Taylor C / Carmody, J Bryan

    JAMA

    2021  Volume 325, Issue 22, Page(s) 2249–2250

    MeSH term(s) COVID-19/epidemiology ; Humans ; Internship and Residency/standards ; Internship and Residency/statistics & numerical data ; Interviews as Topic/methods ; Interviews as Topic/statistics & numerical data ; Quality Improvement ; Specialization ; Time Factors ; United States/epidemiology
    Language English
    Publishing date 2021-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2021.5708
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    Ua VI Zs.88: Show issues Location:
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