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Article: Should I stay, or should I go?

Silverberg, Sarah L

2020 Volume 11, Issue 3, Page(s) e122–e124

Language	English
Publishing date	2020-07-15
Publishing country	Canada
Document type	Journal Article
ZDB-ID	2689512-2
ISSN	1923-1202
ISSN	1923-1202
DOI	10.36834/cmej.68161
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Article ; Online: A Nonhealing Ulcerating Lip Lesion.

Silverberg, Sarah L / Kahane, Alyssa / Kazmi, Kescha

The Journal of pediatrics

2023 Volume 262, Page(s) 113397

MeSH term(s)	Humans ; Lip ; Ulcer/diagnosis ; Ulcer/etiology
Language	English
Publishing date	2023-03-31
Publishing country	United States
Document type	Case Reports
ZDB-ID	3102-1
ISSN	1097-6833 ; 0022-3476
ISSN (online)	1097-6833
ISSN	0022-3476
DOI	10.1016/j.jpeds.2023.113397
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Article ; Online: Delays in Global Disease Outbreak Responses: Lessons from H1N1, Ebola, and Zika.

Hoffman, Steven J / Silverberg, Sarah L

American journal of public health

2018 Volume 108, Issue 3, Page(s) 329–333

Abstract: In global disease outbreaks, there are significant time delays between the source of an outbreak and collective action. Some delay is necessary, but recent delays have been extended by insufficient surveillance capacity and time-consuming efforts to ... ...

Abstract	In global disease outbreaks, there are significant time delays between the source of an outbreak and collective action. Some delay is necessary, but recent delays have been extended by insufficient surveillance capacity and time-consuming efforts to mobilize action. Three public health emergencies of international concern (PHEICs)-H1N1, Ebola, and Zika-allow us to identify and compare sources of delays and consider seven hypotheses about what influences the length of delays. These hypotheses can then motivate further research that empirically tests them. The three PHEICs suggest that deferred global mobilization is a greater source of delay than is poor surveillance capacity. These case study outbreaks support hypotheses that we see quicker responses for novel diseases when outbreaks do not coincide with holidays and when US citizens are infected. They do not support hypotheses that we see quicker responses for more severe outbreaks or those that threaten larger numbers of people. Better understanding the reason for delays can help target policy interventions and identify the kind of global institutional changes needed to reduce the spread and severity of future PHEICs.
MeSH term(s)	Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/prevention & control ; Disease Outbreaks/prevention & control ; Global Health ; Hemorrhagic Fever, Ebola/epidemiology ; Hemorrhagic Fever, Ebola/prevention & control ; Humans ; Influenza A Virus, H1N1 Subtype ; Public Health Surveillance ; Time-to-Treatment ; Zika Virus Infection
Keywords	covid19
Language	English
Publishing date	2018-01-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	121100-6
ISSN	1541-0048 ; 0090-0036 ; 0002-9572
ISSN (online)	1541-0048
ISSN	0090-0036 ; 0002-9572
DOI	10.2105/AJPH.2017.304245
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Article ; Online: COVID-19 infection prevention and control procedures and institutional trust: Perceptions of Canadian intensive care and emergency department nurses.

Silverberg, Sarah L / Puchalski Ritchie, Lisa M / Gobat, Nina / Murthy, Srinivas

Canadian journal of anaesthesia = Journal canadien d'anesthesie

2021 Volume 68, Issue 8, Page(s) 1165–1175

Abstract: Purpose: Healthcare workers must ensure effective infection prevention and control (IPC) to prevent nosocomial spread of SARS-CoV-2, the virus that causes COVID-19. This questionnaire study aims to evaluate Canadian critical care and emergency ... ...

Title translation	Procédures de prévention et de contrôle des infections à la COVID-19 et confiance institutionnelle : perceptions du personnel infirmier des services de soins intensifs et d’urgence au Canada.
Abstract	Purpose: Healthcare workers must ensure effective infection prevention and control (IPC) to prevent nosocomial spread of SARS-CoV-2, the virus that causes COVID-19. This questionnaire study aims to evaluate Canadian critical care and emergency department nurses' readiness to follow IPC guidelines in their workplace, and to understand their perceptions of trust in organizational preparedness, communication, and infection risk. Methods: We adapted an internationally distributed survey for the Canadian context. This cross-sectional questionnaire, incorporating validated scales for items including institutional trust, was distributed by email to nurses via the Canadian Association of Critical Care Nurses and the Canadian Association of Emergency Physicians networks between 16 March and 25 May 2020. We evaluated intensive care unit and emergency department nurses' adherence to IPC protocols, barriers and facilitators to IPC guideline adherence, and their level of institutitonal trust. Results: Three hundred and nineteen nurses responded to the survey. There was higher trust in organizational preparedness among nurses who were older (B = 0.31, P < 0.001) and more experienced (F = 18.09, P < 0.001), and particularly among those with previous experience working in outbreak settings (F = 7.87, P = 0.005). Compared with those without experience working in outbreak settings, respondents with this experience reported higher levels of fear of becoming ill and fear of providing care for COVID-19 patients (χ Conclusion: Canadian nurses had strong self-reported adherence to IPC measures and personal protective equipment use. There were high levels of trust in health system leadership to ensure protective measures are present and reliable. Trust was particularly high among older and more experienced nurses despite these populations reporting higher levels of fear of personal illness.
MeSH term(s)	COVID-19 ; Canada ; Critical Care ; Cross-Sectional Studies ; Emergency Service, Hospital ; Humans ; Nurses ; Perception ; SARS-CoV-2 ; Surveys and Questionnaires ; Trust
Language	English
Publishing date	2021-05-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	91002-8
ISSN	1496-8975 ; 0832-610X
ISSN (online)	1496-8975
ISSN	0832-610X
DOI	10.1007/s12630-021-02028-9
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Article: Canadian critical care nurses experiences on the front lines of the COVID-19 pandemic: a qualitative descriptive study.

Gamble, Kathleen / Murthy, Srinivas / Silverberg, Sarah L / Gobat, Nina / Puchalski Ritchie, Lisa M

BMC nursing

2022 Volume 21, Issue 1, Page(s) 330

Abstract: Background: Recent pandemics have provided important lessons to inform planning for public health emergencies. Despite these lessons, gaps in implementation during the COVID-19 pandemic are evident. Additionally, research to inform interventions to ... ...

Abstract	Background: Recent pandemics have provided important lessons to inform planning for public health emergencies. Despite these lessons, gaps in implementation during the COVID-19 pandemic are evident. Additionally, research to inform interventions to support the needs of front-line nurses during a prolonged pandemic are lacking. We aimed to gain an understanding of critical care nurses' perspectives of the ongoing pandemic, including their opinions of their organization and governments response to the pandemic, to inform interventions to improve the response to the current and future pandemics. Methods: This sub-study is part of a cross-sectional online survey distributed to Canadian critical care nurses at two time points during the pandemic (March-May 2020; April-May 2021). We employed a qualitative descriptive design comprised of three open-ended questions to provide an opportunity for participants to share perspectives not specifically addressed in the main survey. Responses were analyzed using conventional content analysis. Results: One hundred nine of the 168 (64.9%) participants in the second survey responded to the open-ended questions. While perspectives about effectiveness of both their organization's and the government's responses to the pandemic were mixed, most noted that inconsistent and unclear communication made it difficult to trust the information provided. Several participants who had worked during previous pandemics noted that their organization's COVID-19 response failed to incorporate lessons from these past experiences. Many respondents reported high levels of burnout and moral distress that negatively affected both their professional and personal lives. Despite these experiences, several respondents noted that support from co-workers had helped them to cope with the stress and challenges. Conclusion: One year into the pandemic, critical care nurses' lived experiences continue to reflect previously identified challenges and opportunities for improvement in pandemic preparedness and response. These findings suggest that lessons from the current and prior pandemics have been inadequately considered in the COVID-19 response. Incorporation of these perspectives into interventions to improve the health system response, and support the needs of critical care nurses is essential to fostering a resilient health workforce. Research to understand the experience of other front-line workers and to learn from more and less successful interventions, and leaders, is needed.
Language	English
Publishing date	2022-11-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2091496-9
ISSN	1472-6955
ISSN	1472-6955
DOI	10.1186/s12912-022-01105-8
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Article ; Online: Unmatched Canadian medical graduates.

Silverberg, Sarah L / Purdy, Kaylynn M H

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

2018 Volume 190, Issue 4, Page(s) E118

MeSH term(s)	Canada ; Foreign Medical Graduates ; Physicians
Language	English
Publishing date	2018-01-29
Publishing country	Canada
Document type	Letter ; Comment
ZDB-ID	215506-0
ISSN	1488-2329 ; 0008-4409 ; 0820-3946
ISSN (online)	1488-2329
ISSN	0008-4409 ; 0820-3946
DOI	10.1503/cmaj.68737
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Article ; Online: Disparities in availability of skin therapies found in public assistance formularies.

Kamara, Michael / Kuo, Alyce M / Stein, Sarah L / Faith, Esteban Fernandez / Pelletier, Janice L / Jacob, Sharon / Gonzalez, Mercedes E / Silverberg, Nanette B

Journal of the American Academy of Dermatology

2021 Volume 87, Issue 2, Page(s) 411–417

MeSH term(s)	Humans ; Public Assistance
Language	English
Publishing date	2021-08-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2021.08.033
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Article ; Online: Child transmission of SARS-CoV-2: a systematic review and meta-analysis.

Silverberg, Sarah L / Zhang, Bei Yuan / Li, Shu Nan Jessica / Burgert, Conrad / Shulha, Hennady P / Kitchin, Vanessa / Sauvé, Laura / Sadarangani, Manish

BMC pediatrics

2022 Volume 22, Issue 1, Page(s) 172

Abstract: Background: Understanding of the role of children in COVID-19 transmission has significant implications for school and childcare policies, as well as appropriate targeting of vaccine campaigns. The objective of this systematic review was to identify the ...

Abstract	Background: Understanding of the role of children in COVID-19 transmission has significant implications for school and childcare policies, as well as appropriate targeting of vaccine campaigns. The objective of this systematic review was to identify the role of children in SARS-CoV-2 transmission to other children and adults. Methods: MEDLINE, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, and Web of Science were electronically searched for articles published before March 31, 2021. Studies of child-to-child and child-to-adult transmission and quantified the incidence of index and resulting secondary attack rates of children and adults in schools, households, and other congregate pediatric settings were identified. All articles describing confirmed transmission of SARS-CoV-2 from a child were included. PRISMA guidelines for data abstraction were followed, with each step conducted by two reviewers. Results: 40 of 6110 articles identified met inclusion criteria. Overall, there were 0.8 secondary cases per primary index case, with a secondary attack rate of 8.4% among known contacts. The secondary attack rate was 26.4% among adult contacts versus 5.7% amongst child contacts. The pooled estimate of a contact of a pediatric index case being infected as secondary case was 0.10 (95% CI 0.03-0.25). Conclusions: Children transmit COVID-19 at a lower rate to children than to adults. Household adults are at highest risk of transmission from an infected child, more so than adults or children in other settings.
MeSH term(s)	Adult ; COVID-19/epidemiology ; Child ; Family ; Family Characteristics ; Humans ; Incidence ; SARS-CoV-2
Language	English
Publishing date	2022-04-02
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2041342-7
ISSN	1471-2431 ; 1471-2431
ISSN (online)	1471-2431
ISSN	1471-2431
DOI	10.1186/s12887-022-03175-8
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Article ; Online: Alopecia areata treated with hydroxychloroquine: A retrospective study of nine pediatric cases.

Yun, Duri / Silverberg, Nanette B / Stein, Sarah L

Pediatric dermatology

2018 Volume 35, Issue 3, Page(s) 361–365

Abstract: Background/objectives: Alopecia areata is a common hair loss condition that is often emotionally devastating for patients. There is a paucity of effective treatments available. Hydroxychloroquine has been reported as variably effective in inducing ... ...

Abstract	Background/objectives: Alopecia areata is a common hair loss condition that is often emotionally devastating for patients. There is a paucity of effective treatments available. Hydroxychloroquine has been reported as variably effective in inducing significant hair regrowth in adults with alopecia areata. The objective of this retrospective study was to assess the benefit and tolerability of hydroxychloroquine in pediatric alopecia areata. Methods: We conducted a retrospective review of nine children with a history of alopecia areata treated with hydroxychloroquine. Clinical data were obtained from patients treated at two tertiary care centers in the United States between July 1, 2013, and July 1, 2015. Results: Alopecia scores of five patients improved by 6 months of treatment. Four patients experienced no improvement from baseline evaluation. The most common side effect associated with treatment was gastrointestinal intolerance and headache. Conclusion: This retrospective series suggests that hydroxychloroquine can be considered as a treatment option for alopecia areata in children.
MeSH term(s)	Adolescent ; Alopecia Areata/drug therapy ; Child ; Enzyme Inhibitors/adverse effects ; Enzyme Inhibitors/therapeutic use ; Female ; Hair/drug effects ; Hair/growth & development ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/therapeutic use ; Male ; Retrospective Studies ; Treatment Outcome ; United States
Chemical Substances	Enzyme Inhibitors ; Hydroxychloroquine (4QWG6N8QKH)
Language	English
Publishing date	2018-03-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	605539-4
ISSN	1525-1470 ; 0736-8046
ISSN (online)	1525-1470
ISSN	0736-8046
DOI	10.1111/pde.13451
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Article ; Online: The Impact of a Recent Concussion on College-Aged Individuals with Co-Occurring Anxiety: A Qualitative Investigation.

Greenberg, Jonathan / Kanaya, Millan R / Bannon, Sarah M / McKinnon, Ellen / Iverson, Grant L / Silverberg, Noah D / Parker, Robert A / Giacino, Joseph T / Yeh, Gloria Y / Vranceanu, Ana-Maria

International journal of environmental research and public health

2023 Volume 20, Issue 3

Abstract: College-aged individuals with anxiety are vulnerable to developing persistent concussion symptoms, yet evidence-based treatments for this population are limited. Understanding these individuals' perspectives is critical for developing effective ... ...

Abstract	College-aged individuals with anxiety are vulnerable to developing persistent concussion symptoms, yet evidence-based treatments for this population are limited. Understanding these individuals' perspectives is critical for developing effective interventions. We conducted qualitative interviews with 17 college-aged individuals (18-24 years old) with a recent (≤10 weeks) concussion and at least mild anxiety (≥5 on the GAD-7 questionnaire) to understand the life impact of their concussion. We identified 5 themes: (1) disruption to daily activities (e.g., reduced participation in hobbies and physical activity); (2) disruption to relationships (e.g., reduced social engagement, feeling dismissed by others, stigma, and interpersonal friction); (3) disruptions in school/work (e.g., challenges participating due to light sensitivity, cognitive or sleep disturbance, and related emotional distress); (4) changes in view of the self (e.g., feeling "unlike oneself", duller, or more irritable), and (5) finding "silver linings" after the injury (e.g., increased motivation). Concussions impact the lives of college-aged individuals with co-occurring anxiety in a broad range of domains, many of which remain largely neglected in standard concussion clinical assessment and treatment. Assessing and addressing these issues has the potential to limit the negative impact of concussion, promote recovery, and potentially help prevent persistent concussion symptoms in this at-risk population.
MeSH term(s)	Humans ; Young Adult ; Adolescent ; Adult ; Brain Concussion/complications ; Brain Concussion/diagnosis ; Universities ; Schools ; Anxiety/epidemiology ; Anxiety Disorders
Language	English
Publishing date	2023-01-21
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20031988
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