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  1. Book ; Online ; E-Book: Patient-centered medicine

    Stewart, Moira / Brown, Judith Belle / Weston, W. Wayne / Freeman, Thomas / Ryan, Bridget L. / McWilliam, Carol L. / McWhinney, Ian R.

    transforming the clinical method

    2024  

    Abstract: Fully revised by its highly experienced author team, this new edition will be welcomed by a wide international audience comprising all health professionals from medicine, nursing, social work, occupational therapy, physical therapy, pharmacy, veterinary ... ...

    Author's details Moira Stewart, Judith Belle Brown, W Wayne Weston, Thomas R Freeman, Bridget L Ryan, Carol L McWilliam, and Ian R McWhinney
    Abstract Fully revised by its highly experienced author team, this new edition will be welcomed by a wide international audience comprising all health professionals from medicine, nursing, social work, occupational therapy, physical therapy, pharmacy, veterinary medicine, and other fields.
    Keywords Medical personnel and patient ; Medicine-Philosophy ; Patient-centered health care ; Physician and patient
    Subject code 610 ; 610.696
    Language English
    Size 1 Online-Ressource (xx, 342 Seiten)
    Edition Fourth edition
    Publisher CRC Press
    Publishing place Boca Raton, FL
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030707277
    ISBN 978-1-00-384728-1 ; 978-1-003-39467-9 ; 9781032480596 ; 9781032496238 ; 1-00-384728-5 ; 1-003-39467-1 ; 1032480599 ; 1032496231
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Correction: Autologous Muscle-Derived Nerve Wrap for Prevention of Symptomatic Microneuromas in Primary Nerve Repair.

    Bruce, William J / Brown, Amanda L / Romanelli, Michael R / Mailey, Brian A

    Cureus

    2023  Volume 15, Issue 1, Page(s) c98

    Abstract: This corrects the article DOI: 10.7759/cureus.22513.]. ...

    Abstract [This corrects the article DOI: 10.7759/cureus.22513.].
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.c98
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Treatment of avoidant-restrictive food intake disorder in an older adult: A proof-of-concept case study.

    Grunewald, William / Smith, April R / Brown, Tiffany A

    The International journal of eating disorders

    2023  Volume 56, Issue 9, Page(s) 1795–1800

    Abstract: Objective: Cognitive behavioral therapy for Avoidant Restrictive Food Intake Disorder (ARFID; CBT-AR) is an emerging treatment for ARFID. However, this treatment modality has yet to be examined among older adults (e.g., older than 50 years) or with ... ...

    Abstract Objective: Cognitive behavioral therapy for Avoidant Restrictive Food Intake Disorder (ARFID; CBT-AR) is an emerging treatment for ARFID. However, this treatment modality has yet to be examined among older adults (e.g., older than 50 years) or with adults presenting with feeding tubes. To inform future versions of CBT-AR, we present the results of a singular case study (G) of an older male with the sensory sensitivity phenotype of ARFID who presented for treatment with a gastrostomy tube.
    Methods: G was a 71-year-old male who completed eight sessions of CBT-AR in a doctoral training clinic. ARFID symptom severity and comorbid eating pathology changes were examined pre- and post-treatment.
    Results: Posttreatment, G reported significant decreases in ARFID symptom severity and no longer met diagnostic criteria for ARFID. Furthermore, throughout treatment, G reported significant increases in his oral food consumption (vs. calories being pushed through the feeding tube), solid food consumption, and the feeding tube was ultimately removed.
    Discussion: This study provides proof of concept that CBT-AR is potentially effective for older adults and/or those presenting for treatment with feeding tubes. Validation of patient efforts and severity of ARFID symptoms emerged as core to treatment success and should be emphasized when training clinicians in CBT-AR.
    Public significance: Cognitive behavior therapy for ARFID (CBT-AR) is the leading treatment for this disorder; however, it has yet to be tested among older adults or those with feeding tubes. This single-patient case study demonstrates that CBT-AR may be efficacious in reducing ARFID symptom severity among older adults with a feeding tube.
    MeSH term(s) Humans ; Male ; Aged ; Avoidant Restrictive Food Intake Disorder ; Feeding and Eating Disorders ; Retrospective Studies ; Comorbidity ; Eating
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603170-5
    ISSN 1098-108X ; 0276-3478
    ISSN (online) 1098-108X
    ISSN 0276-3478
    DOI 10.1002/eat.23973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1749: Show issues Location:
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  4. Article ; Online: Costly New Alzheimer Disease Medications on the Horizon-Financing Alternatives for Medicare.

    Fleming, William K / Brown, Courtney R / Shrank, William H

    JAMA health forum

    2020  Volume 1, Issue 9, Page(s) e201148

    Language English
    Publishing date 2020-09-01
    Publishing country United States
    Document type Journal Article
    ISSN 2689-0186
    ISSN (online) 2689-0186
    DOI 10.1001/jamahealthforum.2020.1148
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  5. Article ; Online: Development and Psychometric Validation of the Body Trust Scale.

    Grunewald, William / Waitz-Kudla, Sydney N / Levinson, Cheri A / Brown, Tiffany A / Smith, April R

    Assessment

    2024  , Page(s) 10731911231225200

    Abstract: Interoception (e.g., abilities to recognize/attend to internal sensations) is robustly associated with psychopathology. One form of interoception, body trust, is relevant for the development of disordered eating and suicidal thoughts/behaviors. However, ... ...

    Abstract Interoception (e.g., abilities to recognize/attend to internal sensations) is robustly associated with psychopathology. One form of interoception, body trust, is relevant for the development of disordered eating and suicidal thoughts/behaviors. However, measures of body trust are narrow, despite research suggesting body trust is multifaceted. The aim of this study was to develop a comprehensive measure of body trust: The Body Trust Scale (BTS). 479 U.S. adults completed self-report surveys containing the BTS and psychopathology measures. Exploratory and confirmatory factor analyses revealed a three-factor structure: Comfort with One's Body, Physical Attractiveness, and Comfort with Internal Sensations. Factors showed strong construct, convergent, and divergent validity, as well as moderate predictive validity for suicidal thoughts/non-suicidal self-injury. Furthermore, factors showed strong internal consistency, test-retest reliability, and were invariant across the gender binary. The BTS can be used in research and clinical settings to understand how specific facets of body trust relate to psychopathology.
    Language English
    Publishing date 2024-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1362144-0
    ISSN 1552-3489 ; 1073-1911
    ISSN (online) 1552-3489
    ISSN 1073-1911
    DOI 10.1177/10731911231225200
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    Zs.A 4650: Show issues Location:
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  6. Article ; Online: Sarin-Induced Neuroinflammation in Mouse Brain Is Attenuated by the Caspase Inhibitor Q-VD-OPh.

    Shah, Ekta J / Grunwald, William C / Garrett, Teresa L / Brown, Thomas L / Cool, David R

    The Journal of pharmacology and experimental therapeutics

    2024  Volume 388, Issue 2, Page(s) 367–375

    Abstract: Organophosphates cause hyperstimulation of the central nervous system, leading to extended seizures, convulsions, and brain damage. Sarin is a highly toxic organophosphate nerve agent that has been employed in several terrorist attacks. The prolonged ... ...

    Abstract Organophosphates cause hyperstimulation of the central nervous system, leading to extended seizures, convulsions, and brain damage. Sarin is a highly toxic organophosphate nerve agent that has been employed in several terrorist attacks. The prolonged toxicity of sarin may be enhanced by the neuroinflammatory response initiated by the inflammasome, caspase involvement, and generation/release of proinflammatory cytokines. Since neurodegeneration and neuroinflammation are prevalent in sarin-exposed animals, we were interested in evaluating the capacity of quinolyl-valyl-O-methylaspartyl-[-2,6-difluorophenoxy]-methyl ketone (Q-VD-OPh), a pan caspase inhibitor to attenuate neuroinflammation following sarin exposure. To test this hypothesis, sarin-exposed C57BL/6 mice were treated with Q-VD-OPh or negative control quinolyl-valyl-O-methylglutamyl-[-2,6-difluorophenoxy]-methyl ketone, sacrificed at 2- and 14-day time points, followed by removal of the amygdala and hippocampus. A Bio-Rad 23-Plex cytokine analysis was completed on each tissue. The results suggest that exposure to sarin induced a dramatic increase in interleukin-1
    MeSH term(s) Mice ; Animals ; Sarin/toxicity ; Caspase Inhibitors/pharmacology ; Caspase Inhibitors/therapeutic use ; Neuroinflammatory Diseases ; Inflammasomes ; Mice, Inbred C57BL ; Seizures/chemically induced ; Seizures/drug therapy ; Brain ; Cytokines ; Nerve Agents/pharmacology ; Caspases ; Inflammation/chemically induced ; Inflammation/drug therapy ; Organophosphates/pharmacology ; Ketones/adverse effects ; Amino Acid Chloromethyl Ketones ; Quinolines
    Chemical Substances Sarin (B4XG72QGFM) ; Caspase Inhibitors ; quinoline-val-asp(OMe)-CH2-OPH ; Inflammasomes ; Cytokines ; Nerve Agents ; Caspases (EC 3.4.22.-) ; Organophosphates ; Ketones ; Amino Acid Chloromethyl Ketones ; Quinolines
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3106-9
    ISSN 1521-0103 ; 0022-3565
    ISSN (online) 1521-0103
    ISSN 0022-3565
    DOI 10.1124/jpet.123.001820
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  7. Article ; Online: Low Incidence of New Intracranial Aneurysms in Adults With Coarctation of Aorta on Serial Brain Imaging.

    Egbe, Alexander C / Miranda, William R / Jain, C Charles / Burchill, Luke J / Jokhadar, Maan / Brown, Robert D / Connolly, Heidi M

    The American journal of cardiology

    2024  Volume 216, Page(s) 46–47

    MeSH term(s) Adult ; Humans ; Aortic Coarctation/complications ; Aortic Coarctation/diagnostic imaging ; Aortic Coarctation/epidemiology ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/epidemiology ; Incidence ; Aorta ; Neuroimaging/adverse effects
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2024.01.031
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  8. Article ; Online: Conformity to masculine norms, interoceptive dysfunction, and changes in muscle dysmorphia symptoms.

    Grunewald, William / Gagliano, Elena / Brown, Tiffany A / Smith, April R

    Body image

    2023  Volume 45, Page(s) 343–354

    Abstract: Muscle dysmorphia (MD) is a psychiatric illness characterized by preoccupation and compulsive behaviors to increase muscle size/definition. Despite its severity, few risk factors/mechanisms for MD have been identified. Conformity to masculine norms may ... ...

    Abstract Muscle dysmorphia (MD) is a psychiatric illness characterized by preoccupation and compulsive behaviors to increase muscle size/definition. Despite its severity, few risk factors/mechanisms for MD have been identified. Conformity to masculine norms may be a MD risk factor. Furthermore, interoceptive dysfunction may facilitate MD. symptoms, as well as underlie relationships between conformity to masculine norms and MD symptoms. However, research has yet to test the mediating role of interoceptive dysfunction for said relationships. The current study tested if interoceptive dysfunction underlies relationships between conformity to masculine norms and MD symptoms among 269 US men who completed three surveys separated by one month that contained measures of focal constructs. Our sample was majority White, heterosexual, and non-Hispanic. A three-wave autoregressive mediation model was tested in which conformity to masculine norms predicted interoceptive dysfunction, which then predicted MD symptoms. Results indicated that conformity to specific masculine norms predicted both interoceptive dysfunction and MD symptoms over time. Furthermore, our hypothesized mediation pathways were not discovered. Conformity to masculine norms appears to be a risk factor for MD symptoms and interoceptive dysfunction. If clinicians can reduce rigid adherence to masculine stereotypes, this may increase connection with one's body and reduce subsequent MD symptoms.
    MeSH term(s) Male ; Humans ; Masculinity ; Body Image/psychology ; Social Behavior ; Mental Disorders ; Muscles ; Social Conformity
    Language English
    Publishing date 2023-04-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2211449-X
    ISSN 1873-6807 ; 1740-1445
    ISSN (online) 1873-6807
    ISSN 1740-1445
    DOI 10.1016/j.bodyim.2023.03.015
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    Zs.A 6252: Show issues Location:
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  9. Article ; Online: When resilience is cliche and resilience resources are taboo: how language and policies exacerbate mental health disparities.

    Rosenberg, Abby R / Brown, Crystal E / Rosa, William E / Yi-Frazier, Joyce P

    The Lancet. Child & adolescent health

    2023  Volume 7, Issue 4, Page(s) 236–237

    MeSH term(s) Humans ; Mental Health ; Taboo/psychology ; Language ; Policy
    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(23)00005-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Impact of Limiting Vancomycin Loading Doses in Patients With Methicillin-resistant

    Raley, Alec R / Brown, Matthew L / Frawley, Morgan / Oster, Robert A / Edwards, William Seth

    Hospital pharmacy

    2023  Volume 59, Issue 1, Page(s) 118–125

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-08-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1468893-1
    ISSN 0018-5787
    ISSN 0018-5787
    DOI 10.1177/00185787231196435
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