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  1. Article ; Online: Author Correction: One size does not fit all for mutational signatures.

    Ciriello, Giovanni

    Nature cancer

    2022  Volume 1, Issue 4, Page(s) 469

    Language English
    Publishing date 2022-04-19
    Publishing country England
    Document type Published Erratum
    ISSN 2662-1347
    ISSN (online) 2662-1347
    DOI 10.1038/s43018-020-0051-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Materiali per il secondo volume della Introduzione alle scienze dello spirito: Scritti inediti 1880-1893

    Ciriello, Giovanni / Dilthey, Wilhelm

    2017  

    Abstract: As is well-known to the scholars of European philosophical thinking between the eighteenth and twentieth centuries, the great and ambitious plan of diltheyan criticism of the reason of history condensed in a pond-pink Introduction to the Human Sciences ... ...

    Abstract As is well-known to the scholars of European philosophical thinking between the eighteenth and twentieth centuries, the great and ambitious plan of diltheyan criticism of the reason of history condensed in a pond-pink Introduction to the Human Sciences appeared in 1883 only the first volume especially the first two Books. The volume, which we present here, encloses in chronological order the various drafts which, as early as 1880, Dilthey made the work of the second volume of the work, which would have to contain the other four Books, the dedicated ones to the gnoseological, logical and methodological aspects of the philosophical foundation of the so-called sciences of the spirit. An absorbing commitment, which Dilthey will pursue throughout his scientific life, without saving power, will cost him a little in terms of psycho-physical health. In addition to the volume, which besides Breslau drafts also contains the famous Berlin Plan dating back to the early nineties, we also thought it appropriate to include the two dafts of the Althoff Letter dating back to mid-1882, as they also contain useful observations on the designed Introduction to the Human Sciences
    Keywords Philosophy (General)
    Size 1 electronic resource (523 p.)
    Publisher FedOA - Federico II University Press
    Document type Book ; Online
    Note Italian ; Open Access
    HBZ-ID HT020098597
    ISBN 9788868870201 ; 8868870207
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: One size does not fit all for mutational signatures.

    Ciriello, Giovanni

    Nature cancer

    2020  Volume 1, Issue 2, Page(s) 158–159

    MeSH term(s) Biochemical Phenomena ; Genome, Human ; Humans ; Mutation
    Language English
    Publishing date 2020-01-20
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2662-1347
    ISSN (online) 2662-1347
    DOI 10.1038/s43018-020-0033-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Contact allergy to subcutaneous implantable cardioverter defibrillator in a child with Brugada syndrome.

    Ciriello, Giovanni Domenico / Colonna, Diego / Correra, Anna / Romeo, Emanuele / Russo, Maria Giovanna / Sarubbi, Berardo

    Pacing and clinical electrophysiology : PACE

    2024  

    Abstract: Allergic reactions to components of cardiac implantable electronic devices are rare and often go undiagnosed, which can lead to a misdiagnosis of device infection. Contact allergy to subcutaneous implantable cardioverter defibrillator (S-ICD) is ... ...

    Abstract Allergic reactions to components of cardiac implantable electronic devices are rare and often go undiagnosed, which can lead to a misdiagnosis of device infection. Contact allergy to subcutaneous implantable cardioverter defibrillator (S-ICD) is extremely rare. In this report, we present a case of cobalt-related contact allergy in a pediatric patient with Brugada syndrome who underwent S-ICD implantation.
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14921
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The many faces of cancer evolution.

    Ciriello, Giovanni / Magnani, Luca

    iScience

    2021  Volume 24, Issue 5, Page(s) 102403

    Abstract: Cancer cells acquire genotypic and phenotypic changes over the course of the disease. A minority of these changes enhance cell fitness, allowing a tumor to evolve and overcome environmental constraints and treatment. Cancer evolution is driven by diverse ...

    Abstract Cancer cells acquire genotypic and phenotypic changes over the course of the disease. A minority of these changes enhance cell fitness, allowing a tumor to evolve and overcome environmental constraints and treatment. Cancer evolution is driven by diverse processes governed by different rules, such as discrete and irreversible genetic variants and continuous and reversible plastic reprogramming. In this perspective, we explore the role of cell plasticity in tumor evolution through specific examples. We discuss epigenetic and transcriptional reprogramming in "disease progression" of solid tumors, through the lens of the epithelial-to-mesenchymal transition, and "treatment resistance", in the context endocrine therapy in hormone-driven cancers. These examples offer a paradigm of the features and challenges of cell plastic evolution, and we investigate how recent technological advances can address these challenges. Cancer evolution is a multi-faceted process, whose understanding and harnessing will require an equally diverse prism of perspectives and approaches.
    Language English
    Publishing date 2021-05-11
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2021.102403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Irrigated contact force sensing catheter for redo ablation of slow-fast atrioventricular nodal reentrant tachycardia in pediatric and adolescent patients: A case series.

    Ciriello, Giovanni Domenico / Correra, Anna / Russo, Maria Giovanna / Sarubbi, Berardo

    Journal of arrhythmia

    2023  Volume 40, Issue 1, Page(s) 150–153

    Abstract: Conventional nonirrigated catheters cannot be able to create adequate lesions for effective slow pathway modulation in certain cases of pediatric atrioventricular nodal reentrant tachycardia ablation. Irrigated contact force sensing catheters may be ... ...

    Abstract Conventional nonirrigated catheters cannot be able to create adequate lesions for effective slow pathway modulation in certain cases of pediatric atrioventricular nodal reentrant tachycardia ablation. Irrigated contact force sensing catheters may be considered in pediatric and adolescent patients to obtain a more extensive slow pathway modulation for redo ablation, avoiding dangerous radiofrequency applications close to the compact atrioventricular node or complex left-sided procedures.
    Language English
    Publishing date 2023-12-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2696593-8
    ISSN 1883-2148 ; 1880-4276
    ISSN (online) 1883-2148
    ISSN 1880-4276
    DOI 10.1002/joa3.12967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Epistasis and evolutionary dependencies in human cancers.

    Mina, Marco / Iyer, Arvind / Ciriello, Giovanni

    Current opinion in genetics & development

    2022  Volume 77, Page(s) 101989

    Abstract: Cancer evolution is driven by the concerted action of multiple molecular alterations, which emerge and are selected during tumor progression. An alteration is selected when it provides an advantage to the tumor cell. However, the advantage provided by a ... ...

    Abstract Cancer evolution is driven by the concerted action of multiple molecular alterations, which emerge and are selected during tumor progression. An alteration is selected when it provides an advantage to the tumor cell. However, the advantage provided by a specific alteration depends on the tumor lineage, cell epigenetic state, and presence of additional alterations. In this case, we say that an evolutionary dependency exists between an alteration and what influences its selection. Epistatic interactions between altered genes lead to evolutionary dependencies (EDs), by favoring or vetoing specific combinations of events. Large-scale cancer genomics studies have discovered examples of such dependencies, and showed that they influence tumor progression, disease phenotypes, and therapeutic response. In the past decade, several algorithmic approaches have been proposed to infer EDs from large-scale genomics datasets. These methods adopt diverse strategies to address common challenges and shed new light on cancer evolutionary trajectories. Here, we review these efforts starting from a simple conceptualization of the problem, presenting the tackled and still unmet needs in the field, and discussing the implications of EDs in cancer biology and precision oncology.
    MeSH term(s) Humans ; Epistasis, Genetic ; Neoplasms/genetics ; Precision Medicine ; Genomics/methods ; Phenotype
    Language English
    Publishing date 2022-09-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1077312-5
    ISSN 1879-0380 ; 0959-437X
    ISSN (online) 1879-0380
    ISSN 0959-437X
    DOI 10.1016/j.gde.2022.101989
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    Zs.A 3240: Show issues Location:
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  8. Article ; Online: Dapagliflozin in Patients With a Failing Systemic Right Ventricle: Results From the DAPA-SERVE Trial.

    Fusco, Flavia / Scognamiglio, Giancarlo / Abbate, Massimiliana / Merola, Assunta / Grimaldi, Nicola / Ciriello, Giovanni Domenico / Sarubbi, Berardo

    JACC. Heart failure

    2024  Volume 12, Issue 4, Page(s) 789–791

    MeSH term(s) Humans ; Heart Ventricles ; Heart Failure/drug therapy ; Diabetes Mellitus, Type 2 ; Benzhydryl Compounds/therapeutic use ; Glucosides
    Chemical Substances dapagliflozin (1ULL0QJ8UC) ; Benzhydryl Compounds ; Glucosides
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Letter
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2024.01.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The many faces of cancer evolution

    Giovanni Ciriello / Luca Magnani

    iScience, Vol 24, Iss 5, Pp 102403- (2021)

    2021  

    Abstract: Summary: Cancer cells acquire genotypic and phenotypic changes over the course of the disease. A minority of these changes enhance cell fitness, allowing a tumor to evolve and overcome environmental constraints and treatment. Cancer evolution is driven ... ...

    Abstract Summary: Cancer cells acquire genotypic and phenotypic changes over the course of the disease. A minority of these changes enhance cell fitness, allowing a tumor to evolve and overcome environmental constraints and treatment. Cancer evolution is driven by diverse processes governed by different rules, such as discrete and irreversible genetic variants and continuous and reversible plastic reprogramming. In this perspective, we explore the role of cell plasticity in tumor evolution through specific examples. We discuss epigenetic and transcriptional reprogramming in “disease progression” of solid tumors, through the lens of the epithelial-to-mesenchymal transition, and “treatment resistance”, in the context endocrine therapy in hormone-driven cancers. These examples offer a paradigm of the features and challenges of cell plastic evolution, and we investigate how recent technological advances can address these challenges. Cancer evolution is a multi-faceted process, whose understanding and harnessing will require an equally diverse prism of perspectives and approaches.
    Keywords Evolutionary Biology ; Cancer ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Nearly incessant supraventricular tachycardia in a child diagnosed without pacing maneuvers: What's the mechanism?

    Ciriello, Giovanni Domenico / Colonna, Diego / Correra, Anna / Romeo, Emanuele / Russo, Maria Giovanna / Sarubbi, Berardo

    Pacing and clinical electrophysiology : PACE

    2023  Volume 46, Issue 12, Page(s) 1572–1575

    MeSH term(s) Child ; Humans ; Tachycardia, Supraventricular ; Tachycardia, Paroxysmal/surgery ; Catheter Ablation ; Electrocardiography
    Language English
    Publishing date 2023-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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