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Article ; Online: Infant Feeding Practices and Social Support Networks Among Immigrant Chinese American Mothers With Economic Disadvantage in New York City.

Duh-Leong, Carol / Yin, H Shonna / Salcedo, Vanessa / Mui, Angel / Perrin, Eliana M / Yi, Stella S / Zhao, Qiuqu / Gross, Rachel S

Journal of human lactation : official journal of International Lactation Consultant Association

2022 Volume 39, Issue 1, Page(s) 168–177

Abstract: Background: Maternal social support promotes healthy infant feeding practices, which influence healthy growth and development. Less is known about how the interplay of social support networks and multicultural health beliefs may influence infant feeding ...

Abstract	Background: Maternal social support promotes healthy infant feeding practices, which influence healthy growth and development. Less is known about how the interplay of social support networks and multicultural health beliefs may influence infant feeding practices, particularly among immigrant Chinese American mothers with economic disadvantage and low breastfeeding rates. Research aim: To explore the role of social support networks in the development of infant feeding practices in immigrant Chinese American mothers with infants. Methods: This was a prospective, cross-sectional qualitative study where we conducted semi-structured interviews in Mandarin, Cantonese, or English with Chinese American mothers of infants ( Results: Three themes emerged describing how broad transnational communities and close family and friends influence maternal-infant feeding practices: (1) Gathering and processing infant feeding information from broad transnational resources (i.e., from both the mother's country of residence and the mother's country of origin); (2) aligning maternal feeding attitudes with cultural health beliefs of local social networks; and (3) gaining confidence with transactional maternal-infant feeding interactions. Conclusions: Strategies to promote healthy infant feeding should consider how family supports and culturally-relevant coaching can help align multilevel transnational social networks with healthy infant feeding practices.
MeSH term(s)	Female ; Infant ; Humans ; Mothers ; Breast Feeding ; New York City ; Cross-Sectional Studies ; East Asian People ; Prospective Studies ; Emigrants and Immigrants ; Social Support ; Health Knowledge, Attitudes, Practice
Language	English
Publishing date	2022-09-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1138470-0
ISSN	1552-5732 ; 0890-3344
ISSN (online)	1552-5732
ISSN	0890-3344
DOI	10.1177/08903344221121571
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Article ; Online: Pharmacokinetics of intravenous propofol in southern white rhinoceros (Ceratotherium simum simum) after intramuscular etorphine-butorphanol-medetomidine-azaperone.

Berlin, Erin R / Kinney, Matthew E / Howard, Lauren L / Perrin, Kathryn L / Phair, Kristen A / Clancy, Meredith M / Ferris, Rachel L / Knych, Heather K / Mama, Khursheed R

American journal of veterinary research

2023 Volume 84, Issue 4

Abstract: Objective: To determine the pharmacokinetics of a single bolus of intravenous (IV) propofol after intramuscular administration of etorphine, butorphanol, medetomidine, and azaperone in 5 southern white rhinoceros to facilitate reproductive evaluations. ... ...

Abstract	Objective: To determine the pharmacokinetics of a single bolus of intravenous (IV) propofol after intramuscular administration of etorphine, butorphanol, medetomidine, and azaperone in 5 southern white rhinoceros to facilitate reproductive evaluations. A specific consideration was whether propofol would facilitate timely orotracheal intubation. Animals: 5 adult, female, zoo-maintained southern white rhinoceros. Procedures: Rhinoceros were administered etorphine (0.002 mg/kg), butorphanol (0.02 to 0.026 mg/kg), medetomidine (0.023 to 0.025 mg/kg), and azaperone (0.014 to 0.017 mg/kg) intramuscularly (IM) prior to an IV dose of propofol (0.5 mg/kg). Physiologic parameters (heart rate, blood pressure, respiratory rate, and capnography), timed parameters (eg, time to initial effects and intubation), and quality of induction and intubation were recorded following drug administration. Venous blood was collected for analysis of plasma propofol concentrations using liquid chromatography-tandem mass spectrometry at various time points after propofol administration. Results: All animals were approachable following IM drug administration, and orotracheal intubation was achieved at 9.8 ± 2.0 minutes (mean ±SD) following propofol administration. The mean clearance for propofol was 14.2 ± 7.7 ml/min/kg, the mean terminal half-life was 82.4 ± 74.4 minutes, and the maximum concentration occurred at 2.8 ± 2.9 minutes. Two of 5 rhinoceros experienced apnea after propofol administration. Initial hypertension, which improved without intervention, was observed. Clinical relevance: This study provides pharmacokinetic data and insight into the effects of propofol in rhinoceros anesthetized using etorphine, butorphanol, medetomidine, and azaperone. While apnea was observed in 2 rhinoceros, propofol administration allowed for rapid control of the airway and facilitated oxygen administration and ventilatory support.
MeSH term(s)	Female ; Animals ; Etorphine/pharmacology ; Butorphanol ; Azaperone/pharmacology ; Propofol ; Medetomidine/pharmacology ; Hypnotics and Sedatives/pharmacology ; Apnea/drug therapy ; Apnea/veterinary ; Perissodactyla/physiology
Chemical Substances	Etorphine (42M2Y6NU9O) ; Butorphanol (QV897JC36D) ; Azaperone (19BV78AK7W) ; Propofol (YI7VU623SF) ; Medetomidine (MR15E85MQM) ; Hypnotics and Sedatives
Language	English
Publishing date	2023-02-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	390796-x
ISSN	1943-5681 ; 0002-9645
ISSN (online)	1943-5681
ISSN	0002-9645
DOI	10.2460/ajvr.22.12.0224
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Article ; Online: Prenatal Risks to Healthy Food Access and High Birthweight Outcomes.

Duh-Leong, Carol / Perrin, Eliana M / Heerman, William J / Schildcrout, Jonathan S / Wallace, Shelby / Mendelsohn, Alan L / Lee, David C / Flower, Kori B / Sanders, Lee M / Rothman, Russell L / Delamater, Alan M / Gross, Rachel S / Wood, Charles / Yin, Hsiang Shonna

Academic pediatrics

2023

Abstract: Objective: Infants with high birthweight have increased risk for adverse outcomes at birth and across childhood. Prenatal risks to healthy food access may increase odds of high birthweight. We tested whether having a poor neighborhood food environment ... ...

Abstract	Objective: Infants with high birthweight have increased risk for adverse outcomes at birth and across childhood. Prenatal risks to healthy food access may increase odds of high birthweight. We tested whether having a poor neighborhood food environment and/or food insecurity had associations with high birthweight. Methods: We analyzed cross-sectional baseline data in Greenlight Plus, an obesity prevention trial across six US cities (n = 787), which included newborns with a gestational age greater than 34 weeks and a birthweight greater than 2500 g. We assessed neighborhood food environment using the Place-Based Survey and food insecurity using the US Household Food Security Module. We performed logistic regression analyses to assess the individual and additive effects of risk factors on high birthweight. We adjusted for potential confounders: infant sex, race, ethnicity, gestational age, birthing parent age, education, income, and study site. Results: Thirty-four percent of birthing parents reported poor neighborhood food environment and/or food insecurity. Compared to those without food insecurity, food insecure families had greater odds of delivering an infant with high birthweight (adjusted odds ratios [aOR] 1.96, 95% confidence intervals [CI]: 1.01, 3.82) after adjusting for poor neighborhood food environment, which was not associated with high birthweight (aOR 1.35, 95% CI: 0.78, 2.34). Each additional risk to healthy food access was associated with a 56% (95% CI: 4%-132%) increase in high birthweight odds. Conclusions: Prenatal risks to healthy food access may increase high infant birthweight odds. Future studies designed to measure neighborhood factors should examine infant birthweight outcomes in the context of prenatal social determinants of health.
Language	English
Publishing date	2023-09-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2483385-X
ISSN	1876-2867 ; 1876-2859
ISSN (online)	1876-2867
ISSN	1876-2859
DOI	10.1016/j.acap.2023.08.017
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Article ; Online: Material Hardship and Stress from COVID-19 in Immigrant Chinese American Families with Infants.

Duh-Leong, Carol / Yin, H Shonna / Yi, Stella S / Chen, Sabrina L / Mui, Angel / Perrin, Eliana M / Zhao, Qiuqu / Gross, Rachel S

Journal of immigrant and minority health

2021 Volume 24, Issue 1, Page(s) 48–57

Abstract: Material hardship and stress, associated with poor infant outcomes, increased during the Coronavirus Disease 2019 pandemic. Chinese American families were vulnerable to racism-driven disparities. Little is known about maternal perceptions of pandemic ... ...

Abstract	Material hardship and stress, associated with poor infant outcomes, increased during the Coronavirus Disease 2019 pandemic. Chinese American families were vulnerable to racism-driven disparities. Little is known about maternal perceptions of pandemic impacts on their infants, family, and community. Purposive sampling of low-income Chinese American mothers (n = 25) with infants (1-15 months). Semi-structured qualitative interviews conducted in Mandarin, Cantonese, or English were audio-recorded, transcribed, and translated. Transcripts coded using applied thematic analysis in an iterative process of textual analysis until thematic saturation. Three themes emerged: (1) Heightened family hardship included financial strain, disruption of transnational childcare, experiences of racism; (2) Altered infant routines/developmental consequences included using protective equipment on infants, concerns about infant socio-emotional development; (3) Coping strategies included stockpiling essentials, adapting family diets. Strategies to mitigate disparities include expanding social needs screening, correcting misinformation, strengthening support networks, and including low-income Chinese Americans in these efforts.
MeSH term(s)	Asian ; COVID-19 ; Emigrants and Immigrants ; Female ; Humans ; Infant ; Mothers ; SARS-CoV-2
Language	English
Publishing date	2021-09-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2220162-2
ISSN	1557-1920 ; 1557-1912
ISSN (online)	1557-1920
ISSN	1557-1912
DOI	10.1007/s10903-021-01267-8
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Article ; Online: Parenting Stress, Child Weight-Related Behaviors, and Child Weight Status.

White, Michelle J / Schechter, Julia C / Neely, Benjamin / Reyes, Camila / Maguire, Rachel L / Perrin, Eliana M / Ksinan, Albert J / Kollins, Scott H / Fuemmeler, Bernard F

Childhood obesity (Print)

2021 Volume 18, Issue 3, Page(s) 150–159

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Child ; Child Behavior ; Feeding Behavior ; Humans ; Infant, Newborn ; Longitudinal Studies ; Parenting ; Pediatric Obesity/epidemiology ; Sedentary Behavior ; Surveys and Questionnaires
Language	English
Publishing date	2021-09-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2639910-6
ISSN	2153-2176 ; 2153-2168
ISSN (online)	2153-2176
ISSN	2153-2168
DOI	10.1089/chi.2021.0098
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Article ; Online: How COVID-19 impacted child and family health and healthcare: a mixed-methods study incorporating family voices.

Heerman, William J / Gross, Rachel / Lampkin, Jacarra / Nmoh, Ashley / Eatwell, Sagen / Delamater, Alan M / Sanders, Lee / Rothman, Russell L / Yin, H Shonna / Perrin, Eliana M / Flower, Kori B

Translational behavioral medicine

2022 Volume 12, Issue 3, Page(s) 466–479

Abstract: To describe how social disruptions caused by the COVID-19 pandemic impacted child access to healthcare and child health behaviors in 2020. We used mixed-methods to conduct surveys and in-depth interviews with English- and Spanish-speaking parents of ... ...

Abstract	To describe how social disruptions caused by the COVID-19 pandemic impacted child access to healthcare and child health behaviors in 2020. We used mixed-methods to conduct surveys and in-depth interviews with English- and Spanish-speaking parents of young children from five geographic regions in the USA. Participants completed the COVID-19 Exposure and Family Impact Survey (CEFIS). Semistructured telephone interviews were conducted between August and October 2020. Of the 72 parents interviewed, 45.8% of participants were Hispanic, 20.8% Black (non-Hispanic), and 19.4% White (non-Hispanic). On the CEFIS, the average (SD) number of social/family disruptions reported was 10.5 (3.8) out of 25. Qualitative analysis revealed multiple levels of themes that influenced accessing healthcare during the pandemic, including two broad contextual themes: (a) lack of trustworthiness of medical system/governmental organizations, and (b) uncertainty due to lack of consistency across multiple sources of information. This context influenced two themes that shaped the social and emotional environments in which participants accessed healthcare: (a) fear and anxiety and (b) social isolation. However, the pandemic also had some positive impacts on families: over 80% indicated that the pandemic made it "a lot" or "a little" better to care for their new infants. Social and family disruptions due to COVID-19 were common. These disruptions contributed to social isolation and fear, and adversely impacted multiple aspects of child and family health and access to healthcare. Some parents of infants reported improvements in specific health domains such as parenting, possibly due to spending more time together.
MeSH term(s)	COVID-19 ; Child ; Child, Preschool ; Delivery of Health Care ; Family Health ; Humans ; Infant ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2022-02-01
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2586893-7
ISSN	1613-9860 ; 1869-6716
ISSN (online)	1613-9860
ISSN	1869-6716
DOI	10.1093/tbm/ibab166
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Article ; Online: The Prenatal Neighborhood Environment and Geographic Hotspots of Infants with At-risk Birthweights in New York City.

Duh-Leong, Carol / Shonna Yin, H / Gross, Rachel S / Elbel, Brian / Thorpe, Lorna E / Trasande, Leonardo / White, Michelle J / Perrin, Eliana M / Fierman, Arthur H / Lee, David C

Journal of urban health : bulletin of the New York Academy of Medicine

2022 Volume 99, Issue 3, Page(s) 482–491

Abstract: Infants born with low or high ("at-risk") birthweights are at greater risk of adverse health outcomes across the life course. Our objective was to examine whether geographic hotspots of low and high birthweight prevalence in New York City had different ... ...

Abstract	Infants born with low or high ("at-risk") birthweights are at greater risk of adverse health outcomes across the life course. Our objective was to examine whether geographic hotspots of low and high birthweight prevalence in New York City had different patterns of neighborhood risk factors. We performed census tract-level geospatial clustering analyses using (1) birthweight prevalence and maternal residential address from an all-payer claims database and (2) domains of neighborhood risk factors (socioeconomic and food environment) from national and local datasets. We then used logistic regression analysis to identify specific neighborhood risk factors associated with low and high birthweight hotspots. This study examined 2088 census tracts representing 419,025 infants. We found almost no overlap (1.5%) between low and high birthweight hotspots. The majority of low birthweight hotspots (87.2%) overlapped with a socioeconomic risk factor and 95.7% overlapped with a food environment risk factor. Half of high birthweight hotspots (50.0%) overlapped with a socioeconomic risk factor and 48.8% overlapped with a food environment risk factor. Low birthweight hotspots were associated with high prevalence of excessive housing cost, unemployment, and poor food environment. High birthweight hotspots were associated with high prevalence of uninsured persons and convenience stores. Programs and policies that aim to prevent disparities in infant birthweight should examine the broader context by which hotspots of at-risk birthweight overlap with neighborhood risk factors. Multi-level strategies that include the neighborhood context are needed to address prenatal pathways leading to low and high birthweight outcomes.
MeSH term(s)	Birth Weight ; Female ; Humans ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; New York City/epidemiology ; Pregnancy ; Residence Characteristics ; Socioeconomic Factors
Language	English
Publishing date	2022-05-31
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1435288-6
ISSN	1468-2869 ; 1099-3460
ISSN (online)	1468-2869
ISSN	1099-3460
DOI	10.1007/s11524-022-00662-2
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Article ; Online: The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022.

Alzheimer's & dementia : the journal of the Alzheimer's Association

2023 Volume 20, Issue 1, Page(s) 652–694

Abstract: The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging, and cognitive data, and biofluid samples. We used conventional search methods to identify ...

Abstract	The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging, and cognitive data, and biofluid samples. We used conventional search methods to identify 1459 publications from 2021 to 2022 using ADNI data/samples and reviewed 291 impactful studies. This review details how ADNI studies improved disease progression understanding and clinical trial efficiency. Advances in subject selection, detection of treatment effects, harmonization, and modeling improved clinical trials and plasma biomarkers like phosphorylated tau showed promise for clinical use. Biomarkers of amyloid beta, tau, neurodegeneration, inflammation, and others were prognostic with individualized prediction algorithms available online. Studies supported the amyloid cascade, emphasized the importance of neuroinflammation, and detailed widespread heterogeneity in disease, linked to genetic and vascular risk, co-pathologies, sex, and resilience. Biological subtypes were consistently observed. Generalizability of ADNI results is limited by lack of cohort diversity, an issue ADNI-4 aims to address by enrolling a diverse cohort.
MeSH term(s)	Humans ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/therapy ; Amyloid beta-Peptides ; Neuroimaging/methods ; Biomarkers ; Disease Progression ; tau Proteins ; Cognitive Dysfunction/diagnostic imaging
Chemical Substances	Amyloid beta-Peptides ; Biomarkers ; tau Proteins
Language	English
Publishing date	2023-09-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2211627-8
ISSN	1552-5279 ; 1552-5260
ISSN (online)	1552-5279
ISSN	1552-5260
DOI	10.1002/alz.13449
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Article: Parenting Stress, Child Weight-Related Behaviors, and Child Weight Status

White, Michelle J. / Schechter, Julia C. / Neely, Benjamin / Reyes, Camila / Maguire, Rachel L. / Perrin, Eliana M. / Ksinan, Albert J. / Kollins, Scott H. / Fuemmeler, Bernard F.

Childhood obesity. 2022 Apr. 01, v. 18, no. 3

2022

Abstract: Background: There has been limited examination of the association between parenting stress and child weight-related behaviors. We aimed to determine whether parenting stress is associated with child weight-related behaviors, including physical activity, ... ...

Abstract	Background: There has been limited examination of the association between parenting stress and child weight-related behaviors. We aimed to determine whether parenting stress is associated with child weight-related behaviors, including physical activity, screen time, diet, sedentary time, and eating in the absence of hunger (EAH). Secondarily, we assessed association between parenting stress and child weight status. Methods: Mother-child dyads (N = 291) enrolled in the Newborn Epigenetic STudy (NEST), a longitudinal cohort study, completed surveys to describe parenting stress, and child diet. Children participated in the EAH task and wore accelerometers to assess sedentary time and physical activity. Child weight status was assessed using measured height and weight. Outcomes and exposures were examined using generalized linear models and restricted cubic splines as appropriate based on linear lack-of-fit test. Results: Child sedentary time and vegetable consumption were inversely associated with parenting stress (Total Stress B = −0.78; 95% confidence interval [CI]: −1.35 to −0.20; p = 0.017; and Total Stress adjusted odds ratio [aOR] = 0.98; 95% CI: 0.99 to 1.00; p = 0.022, respectively). Child screen time was directly associated with parenting stress (Total Stress = aOR 1.01; 95% CI: 1.00–1.02; p = 0.032). Fast-food intake was nonlinearly associated with parenting stress. There was no evidence of association between parenting stress and child EAH, physical activity, or weight status. Associations between parenting stress and child weight-related behaviors were not moderated by race or family structure. Conclusions: Parenting stress was associated with important child weight-related behaviors but not weight status. Management of parenting stress may represent a reasonable adjunct to family-based behavioral interventions.
Keywords	childhood obesity ; children ; cohort studies ; confidence interval ; epigenetics ; family structure ; hunger ; neonates ; odds ratio ; physical activity ; vegetable consumption
Language	English
Dates of publication	2022-0401
Size	p. 150-159.
Publishing place	Mary Ann Liebert, Inc.
Document type	Article
ZDB-ID	2639910-6
ISSN	2153-2176 ; 2153-2168
ISSN (online)	2153-2176
ISSN	2153-2168
DOI	10.1089/chi.2021.0098
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Dissolved gases in the deep North Atlantic track ocean ventilation processes.

Seltzer, Alan M / Nicholson, David P / Smethie, William M / Tyne, Rebecca L / Le Roy, Emilie / Stanley, Rachel H R / Stute, Martin / Barry, Peter H / McPaul, Katelyn / Davidson, Perrin W / Chang, Bonnie X / Rafter, Patrick A / Lethaby, Paul / Johnson, Rod J / Khatiwala, Samar / Jenkins, William J

Proceedings of the National Academy of Sciences of the United States of America

2023 Volume 120, Issue 11, Page(s) e2217946120

Abstract: Gas exchange between the atmosphere and ocean interior profoundly impacts global climate and biogeochemistry. However, our understanding of the relevant physical processes remains limited by a scarcity of direct observations. Dissolved noble gases in the ...

Abstract	Gas exchange between the atmosphere and ocean interior profoundly impacts global climate and biogeochemistry. However, our understanding of the relevant physical processes remains limited by a scarcity of direct observations. Dissolved noble gases in the deep ocean are powerful tracers of physical air-sea interaction due to their chemical and biological inertness, yet their isotope ratios have remained underexplored. Here, we present high-precision noble gas isotope and elemental ratios from the deep North Atlantic (~32°N, 64°W) to evaluate gas exchange parameterizations using an ocean circulation model. The unprecedented precision of these data reveal deep-ocean undersaturation of heavy noble gases and isotopes resulting from cooling-driven air-to-sea gas transport associated with deep convection in the northern high latitudes. Our data also imply an underappreciated and large role for bubble-mediated gas exchange in the global air-sea transfer of sparingly soluble gases, including O
Language	English
Publishing date	2023-03-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2217946120
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