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Article ; Online: Vaccination coverage rates and attitudes towards mandatory vaccinations among healthcare personnel in tertiary-care hospitals in Greece.

Maltezou, Helena C / Tseroni, Maria / Drositis, Ioannis / Gamaletsou, Maria N / Koukou, Dimitra Maria / Bolikas, Emmanouil / Peskelidou, Emmanuela / Daflos, Charalambos / Panagiotaki, Evangelia / Ledda, Caterina / Pavli, Androula / Moussas, Nikolaos / Kontogianni, Stavroula / Svarna, Eftychia / Ploumidis, Michalis / Spyrou, Andronikos / Chini, Maria / Adamis, Georgios / Lourida, Athanasia /

Hatzigeorgiou, Dimitrios / Gargalianos, Panagiotis / Syrogiannopoulos, George / Sipsas, Nikolaos V

Expert review of vaccines

2022 Volume 21, Issue 6, Page(s) 853–859

Abstract: Objectives: Our aim was to estimate vaccination and susceptibility rates against vaccine-preventable diseases among healthcare personnel (HCP) in eight hospitals.: Methods: Cross-sectional survey.: Results: A total of 1284 HCP participated ( ... ...

Abstract	Objectives: Our aim was to estimate vaccination and susceptibility rates against vaccine-preventable diseases among healthcare personnel (HCP) in eight hospitals. Methods: Cross-sectional survey. Results: A total of 1284 HCP participated (physicians: 31.3%, nursing personnel: 36.6%, paramedical personnel: 11.1%, administrative personnel: 13.2%, supportive personnel: 7.3%). Vaccination rates were 32.9% against measles and mumps, 38.1% against rubella, 5.7% against varicella, 9.2% against hepatitis A, 65.8% against hepatitis B, 31.8% against tetanus-diphtheria, 7.1% against pertussis, 60.2% against influenza, and 80.1% against COVID-19. Susceptibility rates were as follows: 27.8% for measles, 39.6% for mumps, 33.4% for rubella, 22.2% for varicella, 86.3% for hepatitis A, 34.2% for hepatitis B, 68.2% for tetanus-diphtheria, and 92.9% for pertussis. Older HCP had higher susceptibility rates against mumps, rubella, varicella, hepatitis A, hepatitis B, tetanus-diphtheria, and pertussis (p-values <0.001 for all). Mandatory vaccinations were supported by 81.85% of HCP. Conclusions: Although most HCPs supported mandatory vaccinations, significant vaccination gaps, and susceptibility rates were recorded. The proportion of susceptible HCP to measles, mumps, rubella, and varicella has increased in the past decade, mostly because of reduction in acquired cases of natural illness. Vaccination programs for HCP should be developed. A national registry to follow HCP's vaccination rates is urgently needed.
MeSH term(s)	Attitude ; COVID-19 ; Chickenpox ; Cross-Sectional Studies ; Delivery of Health Care ; Diphtheria ; Greece/epidemiology ; Hepatitis A ; Hepatitis B ; Humans ; Measles/epidemiology ; Measles/prevention & control ; Mumps/epidemiology ; Mumps/prevention & control ; Rubella ; Tertiary Care Centers ; Tetanus ; Vaccination ; Vaccination Coverage ; Whooping Cough
Language	English
Publishing date	2022-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2181284-6
ISSN	1744-8395 ; 1476-0584
ISSN (online)	1744-8395
ISSN	1476-0584
DOI	10.1080/14760584.2022.2063118
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Article ; Online: A short review on the aetiology and pathophysiology of alcoholism.

Moussas, George / Christodoulou, Christos / Douzenis, Athanassios

Annals of general psychiatry

2009 Volume 8, Page(s) 10

Abstract: Alcoholism is a chronic remitting and relapsing condition; its aetiology and pathophysiology remains largely obscure despite recent advances. This review summarises the current knowledge about the causation (biological or psychological) of alcohol ... ...

Abstract	Alcoholism is a chronic remitting and relapsing condition; its aetiology and pathophysiology remains largely obscure despite recent advances. This review summarises the current knowledge about the causation (biological or psychological) of alcohol addiction. This involves heredity, candidate genes, alcohol metabolism regulation and the influence of alcohol in the pathophysiology of the different neurotransmitter systems. Alcohol addiction is a multifactorial phenomenon where personality structure, individual state of mind and social influences are in constant interaction with brain neurobiology and pathophysiology. This disorder influences different sexes in different ways and causes major problems, especially in developed societies.
Language	English
Publishing date	2009-05-14
Publishing country	England
Document type	Journal Article
ISSN	1744-859X
ISSN (online)	1744-859X
DOI	10.1186/1744-859X-8-10
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Article: Coping styles of type I and type II alcohol-dependent men undergoing treatment.

Moussas, George / Dandouti, Georgia / Botsis, Alexander / Lykouras, Lefteris

Comprehensive psychiatry

2006 Volume 47, Issue 1, Page(s) 63–68

Abstract: The purpose of this study was to investigate the ways by which individuals with alcohol dependence, who were subgrouped into type I and type II according to the typology criteria of von Knorring et al, (J. Study Alcohol. 1987;48:523-527), cope with life ... ...

Abstract	The purpose of this study was to investigate the ways by which individuals with alcohol dependence, who were subgrouped into type I and type II according to the typology criteria of von Knorring et al, (J. Study Alcohol. 1987;48:523-527), cope with life events. One hundred male alcohol-dependent individuals participating in a therapeutic program composed the study sample. Of the 100, 61 subjects were categorized as type I and 39 subjects as type II. Coping styles were measured using a self-administered questionnaire that includes 8 subscales of coping styles. The type II subgroup scored significantly lower on the suppression subscale and significantly higher on the replacement, mapping, and substitution subscales as compared with the type I subgroup, of which the latter difference was at a tendency level. As regards the remaining 4 coping style subscales, minimization, help seeking, blame, and reversal, no significant differences were found between the 2 patient subgroups. The differences found may be taken into account in the development of therapeutic programs for the 2 subgroups.
MeSH term(s)	Adaptation, Psychological/classification ; Adult ; Alcoholism/psychology ; Greece ; Humans ; Life Change Events ; Male ; Middle Aged ; Multivariate Analysis ; Personality ; Temperament
Language	English
Publishing date	2006-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	127556-2
ISSN	1532-8384 ; 0010-440X
ISSN (online)	1532-8384
ISSN	0010-440X
DOI	10.1016/j.comppsych.2004.07.018
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Article ; Online: A short review on the aetiology and pathophysiology of alcoholism

Douzenis Athanassios / Christodoulou Christos / Moussas George

Annals of General Psychiatry, Vol 8, Iss 1, p

2009 Volume 10

Abstract: Abstract Alcoholism is a chronic remitting and relapsing condition; its aetiology and pathophysiology remains largely obscure despite recent advances. This review summarises the current knowledge about the causation (biological or psychological) of ... ...

Abstract	Abstract Alcoholism is a chronic remitting and relapsing condition; its aetiology and pathophysiology remains largely obscure despite recent advances. This review summarises the current knowledge about the causation (biological or psychological) of alcohol addiction. This involves heredity, candidate genes, alcohol metabolism regulation and the influence of alcohol in the pathophysiology of the different neurotransmitter systems. Alcohol addiction is a multifactorial phenomenon where personality structure, individual state of mind and social influences are in constant interaction with brain neurobiology and pathophysiology. This disorder influences different sexes in different ways and causes major problems, especially in developed societies.
Keywords	Psychiatry ; RC435-571 ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Psychiatry ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2009-05-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
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Article: Examination of type I/type II alcoholism typology in a Greek hospital treatment population.

Lykouras, Lefteris / Moussas, George / Botsis, Alexander

European psychiatry : the journal of the Association of European Psychiatrists

2004 Volume 19, Issue 4, Page(s) 214–218

Abstract: Objective: The study aims at testing the validity of two types of classification of male alcoholism in a Greek hospital treatment sample.: Method: The study population was drawn from male patients with alcohol dependence admitted to the Alcohol ... ...

Abstract	Objective: The study aims at testing the validity of two types of classification of male alcoholism in a Greek hospital treatment sample. Method: The study population was drawn from male patients with alcohol dependence admitted to the Alcohol Treatment Unit of the Psychiatric Hospital of Attica. Seventy-three patients comprised the study sample after exclusion of subjects with alcohol dependence suffering from a comorbid serious medical condition, schizophrenic disorder, bipolar disorder, drug dependence or abuse, organic mental disorder or inability to read. The alcoholics were grouped in type I and II adopting the criterion of age-of-onset used by von Knorring et al. (1985). Impulsivity, suicide risk and violence risk were measured by means of the impulse control scale (ICS), the suicide risk scale (SRS) and the past feelings and acts of violence scale (PFAVS). Results: Fifty patients with alcohol dependence were defined as late-onset and 23 as early-onset. Compared to late-onset patients, early-onset individuals with alcohol dependence had more familial alcoholism (P = 0.032); they were in a higher rate unmarried (P = 0.001), had no stable job before entry in the Unit (P = 0.007) and scored higher on ICS (P = 0.046) and SRS (P = 0.024). Conclusion: The present study confirms type I/type II dichotomy of male alcoholism and also shows that the age-of-onset is a valid classification criterion.
MeSH term(s)	Adult ; Alcoholism/classification ; Alcoholism/ethnology ; Alcoholism/rehabilitation ; Diagnostic and Statistical Manual of Mental Disorders ; Greece ; Hospitalization ; Humans ; Male ; Psychometrics ; Severity of Illness Index ; Suicide, Attempted/statistics & numerical data
Language	English
Publishing date	2004-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	1074337-6
ISSN	1778-3585 ; 0924-9338 ; 0767-399X
ISSN (online)	1778-3585
ISSN	0924-9338 ; 0767-399X
DOI	10.1016/j.eurpsy.2003.12.006
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Article ; Online: Transfers to psychiatry through the consultation-liaison psychiatry service: 11 years of experience.

Christodoulou, Christos / Fineti, Katerina / Douzenis, Athanasios / Moussas, George / Michopoulos, Ioannis / Lykouras, Lefteris

Annals of general psychiatry

2008 Volume 7, Page(s) 10

Abstract: Background: There are only a few reports on issues related to patient transfer from medical and surgical departments to the psychiatric ward by the consultation-liaison psychiatry service, although it is a common practice. Here, we present a study ... ...

Abstract	Background: There are only a few reports on issues related to patient transfer from medical and surgical departments to the psychiatric ward by the consultation-liaison psychiatry service, although it is a common practice. Here, we present a study assessing the factors that influence such transfers. Method: We examined the demographic and clinical backgrounds of a group of patients transferred from internal medicine and surgery to the psychiatric ward over an 11-year period. A comparison was made of this data with data obtained from a group of non-transferred patients, also seen by the same consultation-liaison psychiatry service. Results: According to our findings, the typical transferred patient, either female or male, is single, divorced or widowed, lives alone, belongs to a lower socioeconomic class, presents initially with (on the whole) a disturbed and disruptive behaviour, has had a recent suicide attempt with persistent suicidal ideas, suffers from a mood disorder (mainly depressive and dysthymic disorders), has a prior psychiatric history as well as a prior psychiatric inpatient treatment, and a positive diagnosis on axis II of the five axis system used for mental health diagnosis. Conclusion: The transfer of a patient to the psychiatric ward is a decision depending on multiple factors. Medical diagnoses do not seem to play a major role in the transfer to the psychiatric ward. From the psychiatric diagnosis, depressive and dysthymic disorders are the most common in the transferred population, whilst the transfer is influenced by social factors regarding the patient, the patient's behaviour, the conditions in the ward she/he is treated in and any recent occurrence(s) that increase the anxiety of the staff.
Language	English
Publishing date	2008-08-14
Publishing country	England
Document type	Journal Article
ISSN	1744-859X
ISSN (online)	1744-859X
DOI	10.1186/1744-859X-7-10
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Article ; Online: The Alcohol Use Disorders Identification Test (AUDIT): reliability and validity of the Greek version.

Moussas, George / Dadouti, Georgia / Douzenis, Athanassios / Poulis, Evangelos / Tzelembis, Athanassios / Bratis, Dimitris / Christodoulou, Christos / Lykouras, Lefteris

Annals of general psychiatry

2009 Volume 8, Page(s) 11

Abstract: Background: Problems associated with alcohol abuse are recognised by the World Health Organization as a major health issue, which according to most recent estimations is responsible for 1.4% of the total world burden of morbidity and has been proven to ... ...

Abstract	Background: Problems associated with alcohol abuse are recognised by the World Health Organization as a major health issue, which according to most recent estimations is responsible for 1.4% of the total world burden of morbidity and has been proven to increase mortality risk by 50%. Because of the size and severity of the problem, early detection is very important. This requires easy to use and specific tools. One of these is the Alcohol Use Disorders Identification Test (AUDIT). Aim: This study aims to standardise the questionnaire in a Greek population. Methods: AUDIT was translated and back-translated from its original language by two English-speaking psychiatrists. The tool contains 10 questions. A score >or= 11 is an indication of serious abuse/dependence. In the study, 218 subjects took part: 128 were males and 90 females. The average age was 40.71 years (+/- 11.34). From the 218 individuals, 109 (75 male, 34 female) fulfilled the criteria for alcohol dependence according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), and presented requesting admission; 109 subjects (53 male, 56 female) were healthy controls. Results: Internal reliability (Cronbach alpha) was 0.80 for the controls and 0.80 for the alcohol-dependent individuals. Controls had significantly lower average scores (t test P < 0.001) when compared to the alcoholics. The questionnaire's sensitivity for scores >8 was 0.98 and its specificity was 0.94 for the same score. For the alcohol-dependent sample 3% scored as false negatives and from the control group 1.8% scored false positives. In the alcohol-dependent sample there was no difference between males and females in their average scores (t test P > 0.05). Conclusion: The Greek version of AUDIT has increased internal reliability and validity. It detects 97% of the alcohol-dependent individuals and has a high sensitivity and specificity. AUDIT is easy to use, quick and reliable and can be very useful in detection alcohol problems in sensitive populations.
Language	English
Publishing date	2009-05-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2090401-0
ISSN	1744-859X ; 1744-859X ; 1475-2832
ISSN (online)	1744-859X
ISSN	1744-859X ; 1475-2832
DOI	10.1186/1744-859X-8-11
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Article ; Online: Transfers to psychiatry through the consultation-liaison psychiatry service

Michopoulos Ioannis / Moussas George / Douzenis Athanasios / Fineti Katerina / Christodoulou Christos / Lykouras Lefteris

Annals of General Psychiatry, Vol 7, Iss 1, p

11 years of experience

2008 Volume 10

Abstract: Abstract Background There are only a few reports on issues related to patient transfer from medical and surgical departments to the psychiatric ward by the consultation-liaison psychiatry service, although it is a common practice. Here, we present a ... ...

Abstract	Abstract Background There are only a few reports on issues related to patient transfer from medical and surgical departments to the psychiatric ward by the consultation-liaison psychiatry service, although it is a common practice. Here, we present a study assessing the factors that influence such transfers. Method We examined the demographic and clinical backgrounds of a group of patients transferred from internal medicine and surgery to the psychiatric ward over an 11-year period. A comparison was made of this data with data obtained from a group of non-transferred patients, also seen by the same consultation-liaison psychiatry service. Results According to our findings, the typical transferred patient, either female or male, is single, divorced or widowed, lives alone, belongs to a lower socioeconomic class, presents initially with (on the whole) a disturbed and disruptive behaviour, has had a recent suicide attempt with persistent suicidal ideas, suffers from a mood disorder (mainly depressive and dysthymic disorders), has a prior psychiatric history as well as a prior psychiatric inpatient treatment, and a positive diagnosis on axis II of the five axis system used for mental health diagnosis. Conclusion The transfer of a patient to the psychiatric ward is a decision depending on multiple factors. Medical diagnoses do not seem to play a major role in the transfer to the psychiatric ward. From the psychiatric diagnosis, depressive and dysthymic disorders are the most common in the transferred population, whilst the transfer is influenced by social factors regarding the patient, the patient's behaviour, the conditions in the ward she/he is treated in and any recent occurrence(s) that increase the anxiety of the staff.
Keywords	Psychiatry ; RC435-571 ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Psychiatry ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	940
Language	English
Publishing date	2008-08-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design.

Deftereos, Spyridon G / Siasos, Gerasimos / Giannopoulos, Georgios / Vrachatis, Dimitrios A / Angelidis, Christos / Giotaki, Sotiria G / Gargalianos, Panagiotis / Giamarellou, Helen / Gogos, Charalampos / Daikos, Georgios / Lazanas, Marios / Lagiou, Pagona / Saroglou, Georgios / Sipsas, Nikolaos / Tsiodras, Sotirios / Chatzigeorgiou, Dimitrios / Moussas, Nikolaos / Kotanidou, Anastasia / Koulouris, Nikolaos /

Oikonomou, Evangelos / Kaoukis, Andreas / Kossyvakis, Charalampos / Raisakis, Konstantinos / Fountoulaki, Katerina / Comis, Mihalis / Tsiachris, Dimitrios / Sarri, Eleni / Theodorakis, Andreas / Martinez-Dolz, Luis / Sanz-Sánchez, Jorge / Reimers, Bernhard / Stefanini, Giulio G / Cleman, Michael / Filippou, Dimitrios / Olympios, Christoforos D / Pyrgakis, Vlasios N / Goudevenos, John / Hahalis, George / Kolettis, Theofilos M / Iliodromitis, Efstathios / Tousoulis, Dimitrios / Stefanadis, Christodoulos

Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

2020 Volume 61, Issue 1, Page(s) 42–45

Abstract: Objective: Colchicine has been utilized safely in a variety of cardiovascular clinical conditions. Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component ... ...

Abstract	Objective: Colchicine has been utilized safely in a variety of cardiovascular clinical conditions. Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component in the clinical course of patients with COVID-19. GRECCO-19 will be a prospective, randomized, open-labeled, controlled study to assess the effects of colchicine in COVID-19 complications prevention. Methods: Patients with laboratory confirmed SARS-CoV-2 infection (under RT PCR) and clinical picture that involves temperature >37.5 oC and at least two out of the: i. sustained coughing, ii. sustained throat pain, iii. Anosmia and/or ageusia, iv. fatigue/tiredness, v. PaO2<95 mmHg will be included. Patients will be randomised (1:1) in colchicine or control group. Results: Trial results will be disseminated through peer-reviewed publications and conference presentations. Conclusion: GRECCO-19 trial aims to identify whether colchicine may positively intervene in the clinical course of COVID-19. (ClinicalTrials.gov Identifier: NCT04326790).
MeSH term(s)	Antirheumatic Agents/administration & dosage ; Antirheumatic Agents/adverse effects ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Colchicine/administration & dosage ; Colchicine/adverse effects ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/physiopathology ; Heart Diseases/blood ; Heart Diseases/etiology ; Heart Diseases/prevention & control ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/physiopathology ; Randomized Controlled Trials as Topic ; SARS-CoV-2 ; Symptom Assessment/methods ; Troponin/analysis
Chemical Substances	Antirheumatic Agents ; Troponin ; Colchicine (SML2Y3J35T)
Keywords	covid19
Language	English
Publishing date	2020-04-03
Publishing country	Netherlands
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2215027-4
ISSN	2241-5955 ; 1109-9666
ISSN (online)	2241-5955
ISSN	1109-9666
DOI	10.1016/j.hjc.2020.03.002
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Article ; Online: The Alcohol Use Disorders Identification Test (AUDIT)

Bratis Dimitris / Tzelembis Athanassios / Poulis Evangelos / Douzenis Athanassios / Dadouti Georgia / Moussas George / Christodoulou Christos / Lykouras Lefteris

Annals of General Psychiatry, Vol 8, Iss 1, p

reliability and validity of the Greek version

2009 Volume 11

Abstract: Abstract Background Problems associated with alcohol abuse are recognised by the World Health Organization as a major health issue, which according to most recent estimations is responsible for 1.4% of the total world burden of morbidity and has been ... ...

Abstract	Abstract Background Problems associated with alcohol abuse are recognised by the World Health Organization as a major health issue, which according to most recent estimations is responsible for 1.4% of the total world burden of morbidity and has been proven to increase mortality risk by 50%. Because of the size and severity of the problem, early detection is very important. This requires easy to use and specific tools. One of these is the Alcohol Use Disorders Identification Test (AUDIT). Aim This study aims to standardise the questionnaire in a Greek population. Methods AUDIT was translated and back-translated from its original language by two English-speaking psychiatrists. The tool contains 10 questions. A score ≥ 11 is an indication of serious abuse/dependence. In the study, 218 subjects took part: 128 were males and 90 females. The average age was 40.71 years (± 11.34). From the 218 individuals, 109 (75 male, 34 female) fulfilled the criteria for alcohol dependence according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), and presented requesting admission; 109 subjects (53 male, 56 female) were healthy controls. Results Internal reliability (Cronbach α) was 0.80 for the controls and 0.80 for the alcohol-dependent individuals. Controls had significantly lower average scores (t test P < 0.001) when compared to the alcoholics. The questionnaire's sensitivity for scores >8 was 0.98 and its specificity was 0.94 for the same score. For the alcohol-dependent sample 3% scored as false negatives and from the control group 1.8% scored false positives. In the alcohol-dependent sample there was no difference between males and females in their average scores (t test P > 0.05). Conclusion The Greek version of AUDIT has increased internal reliability and validity. It detects 97% of the alcohol-dependent individuals and has a high sensitivity and specificity. AUDIT is easy to use, quick and reliable and can be very useful in detection alcohol problems in sensitive populations.
Keywords	Psychiatry ; RC435-571 ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Psychiatry ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	150
Language	English
Publishing date	2009-05-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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