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  1. Article ; Online: Trends in use of composite endpoints in clinical trials: A comparison between acute heart failure trials and COVID-19 trials.

    Shi, Lan / Lindsell, Christopher John / Liu, Dandan

    Journal of clinical and translational science

    2024  Volume 8, Issue 1, Page(s) e55

    Abstract: Composite endpoints can encode multiple pieces of information and are increasingly adopted in clinical trials. Advocacy for using composite endpoints began decades ago in cardiovascular trials, leading to incorporation of patient-oriented outcomes and ... ...

    Abstract Composite endpoints can encode multiple pieces of information and are increasingly adopted in clinical trials. Advocacy for using composite endpoints began decades ago in cardiovascular trials, leading to incorporation of patient-oriented outcomes and consideration of a hierarchical ranking system. The use of composite endpoints in coronavirus disease (COVID-19) trials has evolved similarly. We conducted a literature review to investigate the use of composite endpoints in acute heart failure and COVID-19 clinical trials. The results showed more frequent use of patient-oriented outcomes and ordinal composite endpoints in COVID-19 trials, which might be driven by global consensus on a set of common outcome measures.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ISSN 2059-8661
    ISSN (online) 2059-8661
    DOI 10.1017/cts.2024.492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Does urbanization reduce the multi-functional value of cultivated land? Evidence from China

    Wei Shi / Dandan Liu

    Frontiers in Environmental Science, Vol

    2023  Volume 11

    Abstract: The contradiction between urbanization and cultivated land conservation needs to be resolved urgently. The coupling of cultivated land production, compound utilization and ecological protection is a hot topic for policymakers and researchers. Based on ... ...

    Abstract The contradiction between urbanization and cultivated land conservation needs to be resolved urgently. The coupling of cultivated land production, compound utilization and ecological protection is a hot topic for policymakers and researchers. Based on the panel data of 31 provinces in China from 2002 to 2018, this paper estimated the impact of urbanization on the quantity and structure of cultivated land functional value using a fixed effect model. The results show that the multi-functional value of cultivated land fluctuates in time series. There was obvious synergistic relationship among different functions of cultivated land, and the synergistic relationship was gradually weakened. Urbanization did not decrease the multi-functional value of cultivated land, and the producing function of cultivated land was improved most obviously. The value of producing function and social security function in main-producing areas is the most obvious response to urbanization. The culture of main marketing areas has the highest response to urbanization, and urbanization has reduced the ecological function of grain main marketing areas. Urbanization has reduced the diversified types of cultivated land, and the function positioning of cultivated land is gradually obvious. Therefore, policymakers should pay attention to the dialectical relationship between the total amount and structure of multi-functional cultivated land and implement regional differentiation policy of multi-functional cultivated land utilization.
    Keywords urbanization ; cultivated land ; multifunction ; value accounting ; fixed effect model ; Environmental sciences ; GE1-350
    Subject code 710
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Bullying Victimization and Malevolent Creativity in Rural Adolescents: The Longitudinal Mediational Role of Hostile Attribution.

    Tong, Dandan / Shi, Yanan / Gu, Xiaojing / Lu, Peng

    Cyberpsychology, behavior and social networking

    2024  

    Abstract: Extensive research has documented bully victimization as a pivotal risk factor contributing to aggressive behaviors among adolescents. Particularly, the negative outcome of increased aggressive behaviors may be exacerbated when the aggressive actions are ...

    Abstract Extensive research has documented bully victimization as a pivotal risk factor contributing to aggressive behaviors among adolescents. Particularly, the negative outcome of increased aggressive behaviors may be exacerbated when the aggressive actions are novel and difficult to detect. The present study aims to explore the complex relationships between cyberbullying and school bullying victimization and malevolent creativity and the potential mediating role of hostile attribution using two-wave longitudinal data. The present study analyzed data from 262 rural adolescents. The results revealed that cyberbullying victimization significantly predicted malevolent creativity, whereas school bullying victimization did not. Hostile attribution served as a mediator in the relationship between cyberbullying victimization and malevolent creativity in the longitudinal models. These findings provide significant implications for mitigating the negative influence of bullying victimization on the emergence of malevolent creativity in rural adolescents.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2545735-4
    ISSN 2152-2723 ; 2152-2715
    ISSN (online) 2152-2723
    ISSN 2152-2715
    DOI 10.1089/cyber.2023.0499
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  4. Article ; Online: Consequences of abolishing the COVID-19 zero-tolerance policy in Shanghai: Lessons for future responses.

    Xu, Zhongqing / Shi, Dandan / Ding, Jingjing / Lu, Hong / Shen, Xiaoyi / Hambly, Brett / Bao, Shisan

    Australian journal of general practice

    2024  Volume 53, Issue 1-2, Page(s) 78–80

    MeSH term(s) Humans ; COVID-19 ; China/epidemiology ; Policy
    Language English
    Publishing date 2024-02-05
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2924889-9
    ISSN 2208-7958 ; 2208-794X
    ISSN (online) 2208-7958
    ISSN 2208-794X
    DOI 10.31128/AJGP/05-23-6830
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The anti-

    Jiang, Yucong / Shi, Yuehong / Hu, Dandan / Song, Xingju

    Frontiers in veterinary science

    2022  Volume 9, Page(s) 972500

    Abstract: Toxoplasma ... ...

    Abstract Toxoplasma gondii
    Language English
    Publishing date 2022-08-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2022.972500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The efficacy and safety of Trilaciclib in preventing chemotherapy-induced myelosuppression: a systematic review and meta-analysis of randomized controlled trials.

    Qiu, Jingyue / Sheng, Dandan / Lin, Fei / Jiang, Peng / Shi, Ning

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1157251

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1157251
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  7. Article ; Online: Trends in the disease burden of anxiety disorders in middle-aged and older adults in China.

    Zhi, Zeng / Yan, Shi / Yijuan, He / Jiahuan, Zheng / Xiaohan, Jiang / Dandan, Chen

    BMC psychology

    2024  Volume 12, Issue 1, Page(s) 83

    Abstract: Background: Anxiety disorders in middle-aged and older adults are an important public health concern in China. Based on the data in the global disease burden (GDB) research database, this study evaluated and analyzed the trend of the disease burden of ... ...

    Abstract Background: Anxiety disorders in middle-aged and older adults are an important public health concern in China. Based on the data in the global disease burden (GDB) research database, this study evaluated and analyzed the trend of the disease burden of middle-aged and older patients living with anxiety in China in the past 30 years.
    Methods: The incidence and disability-adjusted life years (DALYs) data of anxiety disorders in China for individuals aged 45-89 years were collected from the Global Burden of Disease Study 2019, and the effects of age, period, and cohort on the incidence of and DALY rate for anxiety disorders were analysed using an age-period-cohort model. Because of the COVID-19 pandemic, the global disease burden research database has not been updated since 2019. However, this did not affect the analysis of future trends in this study, which combined data in the past three decades from 1990 to 2019.
    Results: (1) The overall age-standardised incidence rate (ASIR) and age-standardised DALY rate (ASDR) for anxiety disorders in middle-aged and older adults in China decreased by 4.0 and 7.7% from 1990 to 2019, respectively, and the ASIR and ASDR were always higher in women than in men. (2)Age-period-cohort analysis showed that the net drifts for incidence and DALY rate were - 0.27% and - 0.55% per year, respectively. For both genders, the local drifts for incidence were lower than zero in those aged 45-79 years and higher than zero in those aged 80-89 years; the local drifts for the DALY rate were lower than zero in all groups. (3) From the 1990-1994 to 2015-2019, the relative risks of anxiety disorder incidence and DALY decreased by 5.6 and 7.3% in men and 4.3 and 11.7% in women, respectively.
    Conclusion: The disease burden of anxiety disorders in middle-aged and older adults in China has been relieved over the past 30 years; however, recent ASDR, ASDR, period, and cohort effects have shown adverse trends. The incidence and DALY rate decreased with age in women, while men showed a trend of increasing first and decreasing afterwards.
    MeSH term(s) Middle Aged ; Female ; Humans ; Male ; Aged ; Pandemics ; Anxiety Disorders/epidemiology ; Cost of Illness ; Anxiety/epidemiology ; China/epidemiology ; Quality-Adjusted Life Years
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2705921-2
    ISSN 2050-7283 ; 2050-7283
    ISSN (online) 2050-7283
    ISSN 2050-7283
    DOI 10.1186/s40359-024-01575-2
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  8. Article: The adverse events of CDK4/6 inhibitors for HR+/ HER2- breast cancer: an umbrella review of meta-analyses of randomized controlled trials.

    Pu, Dongqing / Wu, Yue / Xu, Debo / Shi, Guangxi / Chen, Hanhan / Feng, Dandan / Zhang, Mengdi / Li, Jingwei

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1269922

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1269922
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  9. Article: A lung cancer risk warning model based on tongue images.

    Shi, Yulin / Guo, Dandan / Chun, Yi / Liu, Jiayi / Liu, Lingshuang / Tu, Liping / Xu, Jiatuo

    Frontiers in physiology

    2023  Volume 14, Page(s) 1154294

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-06-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1154294
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  10. Article ; Online: Changes in Epstein-Barr virus infections in the children before and after the COVID-19 pandemic in Zhengzhou, China.

    Wang, Yafeng / Shi, Lihuan / Liu, Dandan / Mao, Yanna / Liu, Wei

    Journal of medical virology

    2023  Volume 95, Issue 3, Page(s) e28597

    MeSH term(s) Humans ; Child ; Epstein-Barr Virus Infections/epidemiology ; Herpesvirus 4, Human ; Pandemics ; COVID-19/epidemiology ; China/epidemiology
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28597
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
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