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Book: The Park Chung Hee era

Cho, Lee-Jay

economic development and modernization of the Republic of Korea

2019

Abstract: ... the general : lessons from Park Chung Hee's development strategy for Russia in transition / Alexandre Y ... Overview : a historical and institutional perspective / Lee-Jay Cho -- Antecedent ... Andrew Mason and Lee-Jay Cho -- A new perspective on the "name-changing policy" in Korea / Pal-Yong Moon ...

Author's details	edited by Lee-Jay Cho
Abstract	Overview : a historical and institutional perspective / Lee-Jay Cho -- Antecedent to economic growth : President Rhee and Prime Minister Chang / Robert T. Oliver -- Institutional reforms for national economic management / Ki Jun Rhee -- Role of business corporations and entrepreneurs in the initial stage of rapid economic development in the Republic of Korea / Bon Ho Koo and Eun Mee Kim -- Dynamics of industrial policy I : export-oriented industrialization, 1961-1971 / Kwang Suk Kim -- Dynamics of industrial policy II : six episodes of heavy and chemical industries development / Kwang Suk Kim -- Science and technology policy in state-guided modernization / Linsu Kim -- Population and development : the Park regime's legacy / Andrew Mason and Lee-Jay Cho -- A new perspective on the "name-changing policy" in Korea / Pal-Yong Moon -- Role of the United States in the economic development of Korea / Lee-Jay Cho -- The bear and the general : lessons from Park Chung Hee's development strategy for Russia in transition / Alexandre Y. Mansourov -- South Korea's struggle for economic development during the Park regime : a Japanese perspective / Toshio Watanabe
Keywords	Korea (South)
Language	English
Size	pages cm
Document type	Book
Note	Includes bibliographical references and index
ISBN	9780824879792 ; 9780824880965 ; 0824879791 ; 082488096X
Database	ECONomics Information System

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Article ; Online: Refugee and Migrant Integration in Urban Spatial Structures and City Development

Sreenidhi Konduri / In-Hee Lee

Sustainability, Vol 15, Iss 24, p

Case Study of Busan, South Korea

2023 Volume 16857

Abstract: With the increasing protracted displacements and overall worldwide migration in recent decades, local integration has been considered a durable solution. Accordingly, global agendas have recommended the inclusion of migrant populations, especially within ...

Abstract	With the increasing protracted displacements and overall worldwide migration in recent decades, local integration has been considered a durable solution. Accordingly, global agendas have recommended the inclusion of migrant populations, especially within urban frameworks, as cities have always been deemed as migrant hubs. This study examines the influence of migrant spatial integration in city development and municipal policy against the historic backdrop of Busan. From liberation (1945) to post-war industrialization (1960s–1980s), Busan experienced population surges with the inflow of refugees and migrants that historically changed government policies and urban development plans. Based on archival research, secondary data, and GIS mapping, this study explores the influence of migrant populations on the city demographics, physical development, and housing initiatives during different periods. The findings of this study highlight the “local turn” in migrant spatial integration and the production of new urban geographies that portray “humanitarian” and “migrant” urbanism, thereby offering insights into sustainable urban futures for migrant and displaced populations.
Keywords	migrant integration ; municipal policy ; urban planning history ; Busan ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	710
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: ADGR: Admixture-Informed Differential Gene Regulation.

Lee, In-Hee / Kong, Sek Won

Genes

2023 Volume 14, Issue 1

Abstract: The regulatory elements in proximal and distal regions of genes are involved in the regulation of gene expression. Risk alleles in intronic and intergenic regions may alter gene expression by modifying the binding affinity and stability of diverse DNA- ... ...

Abstract	The regulatory elements in proximal and distal regions of genes are involved in the regulation of gene expression. Risk alleles in intronic and intergenic regions may alter gene expression by modifying the binding affinity and stability of diverse DNA-binding proteins implicated in gene expression regulation. By focusing on the local ancestral structure of coding and regulatory regions using the paired whole-genome sequence and tissue-wide transcriptome datasets from the Genotype-Tissue Expression project, we investigated the impact of genetic variants, in aggregate, on tissue-specific gene expression regulation. Local ancestral origins of the coding region, immediate and distant upstream regions, and distal regulatory region were determined using RFMix with the reference panel from the 1000 Genomes Project. For each tissue, inter-individual variation of gene expression levels explained by concordant or discordant local ancestry between coding and regulatory regions was estimated. Compared to European, African descent showed more frequent change in local ancestral structure, with shorter haplotype blocks. The expression level of the Adenosine Deaminase Like (
MeSH term(s)	Humans ; Alleles ; Black People ; Gene Expression Regulation/genetics ; Haplotypes/genetics ; White People
Language	English
Publishing date	2023-01-05
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes14010147
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Article ; Online: ADGR: Admixture-Informed Differential Gene Regulation

Lee, In-Hee / Kong, Sek Won

Genes (Basel). 2023 Jan. 05, v. 14, no. 1

2023

Abstract	The regulatory elements in proximal and distal regions of genes are involved in the regulation of gene expression. Risk alleles in intronic and intergenic regions may alter gene expression by modifying the binding affinity and stability of diverse DNA-binding proteins implicated in gene expression regulation. By focusing on the local ancestral structure of coding and regulatory regions using the paired whole-genome sequence and tissue-wide transcriptome datasets from the Genotype-Tissue Expression project, we investigated the impact of genetic variants, in aggregate, on tissue-specific gene expression regulation. Local ancestral origins of the coding region, immediate and distant upstream regions, and distal regulatory region were determined using RFMix with the reference panel from the 1000 Genomes Project. For each tissue, inter-individual variation of gene expression levels explained by concordant or discordant local ancestry between coding and regulatory regions was estimated. Compared to European, African descent showed more frequent change in local ancestral structure, with shorter haplotype blocks. The expression level of the Adenosine Deaminase Like (ADAL) gene was significantly associated with admixed ancestral structure in the regulatory region across multiple tissue types. Further validations are required to understand the impact of the local ancestral structure of regulatory regions on gene expression regulation in humans and other species.
Keywords	adenosine deaminase ; ancestry ; data collection ; gene expression ; gene expression regulation ; genes ; haplotypes ; risk ; transcriptome
Language	English
Dates of publication	2023-0105
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2527218-4
ISSN	2073-4425
ISSN	2073-4425
DOI	10.3390/genes14010147
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Exploring the Safety and Efficacy of Organic Light-Emitting Diode in Skin Rejuvenation and Wound Healing.

Lee, Young In / Lee, Sang Gyu / Ham, Seoyoon / Jung, Inhee / Suk, Jangmi / Lee, Ju Hee

Yonsei medical journal

2024 Volume 65, Issue 2, Page(s) 98–107

Abstract: Purpose: Photobiomodulation (PBM), encompassing low-energy laser treatment and light-emitting diode (LED) phototherapy, has demonstrated positive impacts on skin rejuvenation and wound healing. Organic light-emitting diodes (OLEDs) present a promising ... ...

Abstract	Purpose: Photobiomodulation (PBM), encompassing low-energy laser treatment and light-emitting diode (LED) phototherapy, has demonstrated positive impacts on skin rejuvenation and wound healing. Organic light-emitting diodes (OLEDs) present a promising advancement as wearable light sources for PBM. However, the biological and biochemical substantiation of their skin rejuvenation and wound healing effects remains limited. This study aimed to ascertain the safety and efficacy of OLEDs as a next-generation PBM modality through comprehensive in vitro and in vivo investigations. Materials and methods: Cell viability assays and human ex vivo skin analyses were performed after exposure to OLED and LED irradiation to examine their safety. Subsequent evaluations examined expression levels and wound healing effects in human dermal fibroblasts (HDFs) using quantitative reverse transcription-polymerase chain reaction, enzyme-linked immunosorbent assay, and wound healing assays post-irradiation. Additionally, an in vivo study was conducted using a ultra violet (UV)-irradiated animal skin model to explore the impact of OLED exposure on dermal collagen density and wrinkles, employing skin replica and tissue staining techniques. Results: OLED irradiation had no significant morphological effects on human skin tissue, but caused a considerably higher expression of collagen than the control and LED-treated groups. Moreover, OLED irradiation reduced the expression levels of matrix metalloproteinases (MMPs) more effectively than did LED on HDFs. OLED irradiation group in HDFs had significantly higher expression levels of growth factors compared to the control group, but similar to those in the LED irradiation group. In addition, OLED irradiation on photo-aged animal skin model resulted in increased collagen fiber density in the dermis while reducing ultra violet radiation-mediated skin wrinkles and roughness, as shown in the skin replica. Conclusion: This study established comparable effectiveness between OLED and LED irradiation in upregulating collagen and growth factor expression levels while downregulating MMP levels in vitro. In the UV-irradiated animal skin model, OLED exposure post UV radiation correlated with reduced skin wrinkles and augmented dermal collagen density. Accelerated wound recovery and demonstrated safety further underscore OLEDs' potential as a future PBM modality alongside LEDs, offering promise in the realms of skin rejuvenation and wound healing.
MeSH term(s)	Animals ; Humans ; Aged ; Rejuvenation ; Wound Healing/physiology ; Wound Healing/radiation effects ; Skin ; Phototherapy/methods ; Collagen/metabolism
Chemical Substances	Collagen (9007-34-5)
Language	English
Publishing date	2024-01-08
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	303740-x
ISSN	1976-2437 ; 0513-5796
ISSN (online)	1976-2437
ISSN	0513-5796
DOI	10.3349/ymj.2023.0125
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Article: Investigating the Influence of PbS Quantum Dot-Decorated TiO

Kim, Yeonjae / Seo, Joo-Won / Lee, In-Hee / Kim, Jae-Yup

Materials (Basel, Switzerland)

2023 Volume 17, Issue 1

Abstract: To maximize the photoelectrochemical (PEC) hydrogen production performance of quantum dot (QD)-decorated photoelectrodes, it is crucial to prioritize the optimization of electrode's structure, including thickness and porosity. In this study, we prepare ... ...

Abstract	To maximize the photoelectrochemical (PEC) hydrogen production performance of quantum dot (QD)-decorated photoelectrodes, it is crucial to prioritize the optimization of electrode's structure, including thickness and porosity. In this study, we prepare PbS QD-decorated mesoporous TiO
Language	English
Publishing date	2023-12-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma17010225
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Article ; Online: Quantitative trait locus analysis for endophenotypes reveals genetic substrates of core symptom domains and neurocognitive function in autism spectrum disorder.

Lee, In-Hee / Koelliker, Ekaterina / Kong, Sek Won

Translational psychiatry

2022 Volume 12, Issue 1, Page(s) 407

Abstract: Autism spectrum disorder (ASD) represents a heterogeneous group of neurodevelopmental disorders and is largely attributable to genetic risk factors. Phenotypic and genetic heterogeneity of ASD have been well-recognized; however, genetic substrates for ... ...

Abstract	Autism spectrum disorder (ASD) represents a heterogeneous group of neurodevelopmental disorders and is largely attributable to genetic risk factors. Phenotypic and genetic heterogeneity of ASD have been well-recognized; however, genetic substrates for endophenotypes that constitute phenotypic heterogeneity are not yet known. In the present study, we compiled data from the Autism Genetic Resource Exchange, which contains the demographic and detailed phenotype information of 11,961 individuals. Notably, the whole-genome sequencing data available from MSSNG and iHART for 3833 individuals in this dataset was used to perform an endophenotype-wide association study. Using a linear mixed model, genome-wide association analyses were performed for 29 endophenotype scores and 0.58 million common variants with variant allele frequency ≥ 5%. We discovered significant associations between 9 genetic variants and 6 endophenotype scores comprising neurocognitive development and severity scores for core symptoms of ASD at a significance threshold of p < 5 × 10
MeSH term(s)	Autism Spectrum Disorder/genetics ; Endophenotypes ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; Humans ; Quantitative Trait Loci
Language	English
Publishing date	2022-09-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2609311-X
ISSN	2158-3188 ; 2158-3188
ISSN (online)	2158-3188
ISSN	2158-3188
DOI	10.1038/s41398-022-02179-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Antioxidant, Anti-Inflammatory and Antithrombotic Effects of Ginsenoside Compound K Enriched Extract Derived from Ginseng Sprouts.

Baik, In-Hee / Kim, Kyung-Hee / Lee, Kyung-Ae

Molecules (Basel, Switzerland)

2021 Volume 26, Issue 13

Abstract: Partially purified ginsenoside extract (PGE) and compound K enriched extract (CKE) were prepared from ginseng sprouts, and their antioxidant, anti-inflammatory and antithrombotic effects were investigated. Compared to the 6-year-old ginseng roots, ... ...

Abstract	Partially purified ginsenoside extract (PGE) and compound K enriched extract (CKE) were prepared from ginseng sprouts, and their antioxidant, anti-inflammatory and antithrombotic effects were investigated. Compared to the 6-year-old ginseng roots, ginseng sprouts were found to have a higher content of phenolic compounds, saponin and protopanaxadiol-type ginsenoside by about 56%, 36% and 43%, respectively. PGE was prepared using a macroporous adsorption resin, and compound K(CK) was converted and enriched from the PGE by enzymatic hydrolysis with a conversion rate of 75%. PGE showed higher effects than CKE on radical scavenging activity in antioxidant assays. On the other hand, CKE reduced nitric oxide levels more effectively than PGE in RAW 264.7 cells. CKE also reduced pro-inflammatory cytokines, such as tumor necrosis factor-α, interleukin (IL)-1β and IL-6 than PGE. Tail bleeding time and volume were investigated after administration of CKE at 70-150 mg/kg/day to mice. CKE administered group showed a significant increase or increased tendency in bleeding time than the control group. Bleeding volume in the CKE group increased than the control group, but not as much as in the aspirin group. In conclusion, ginseng sprouts could be an efficient source of ginsenoside, and CKE converted from the ginsenosides showed antioxidant, anti-inflammatory and antithrombotic effects. However, it was estimated that the CKE might play an essential role in anti-inflammatory effects rather than antioxidant effects.
MeSH term(s)	Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Cytokines/metabolism ; Fibrinolytic Agents/pharmacology ; Ginsenosides/pharmacology ; Hemorrhage/drug therapy ; Mice ; Mice, Inbred ICR ; Nitric Oxide/metabolism ; Panax/chemistry ; Plant Extracts/pharmacology ; RAW 264.7 Cells
Chemical Substances	Anti-Inflammatory Agents ; Antioxidants ; Cytokines ; Fibrinolytic Agents ; Ginsenosides ; Plant Extracts ; Nitric Oxide (31C4KY9ESH) ; ginsenoside M1 (A9RLM212CY)
Language	English
Publishing date	2021-07-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules26134102
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Article ; Online: Efficacy and safety of a home-use handheld multi-energy-based device for skin rejuvenation: clinical, ex vivo, and histological studies.

Choi, Sooyeon / Kim, Jemin / Lee, Young In / Lee, Sang Gyu / Jung, Inhee / Suk, Jangmi / Lee, Ju Hee

Lasers in medical science

2024 Volume 39, Issue 1, Page(s) 38

Abstract: Alongside increases in the average lifespan and a growing interest in anti-aging remedies, the demand for at-home skincare devices is rapidly expanding in the cosmetic market. This study aimed to assess the safety and efficacy of a novel home-use ... ...

Abstract	Alongside increases in the average lifespan and a growing interest in anti-aging remedies, the demand for at-home skincare devices is rapidly expanding in the cosmetic market. This study aimed to assess the safety and efficacy of a novel home-use handheld multi-energy-based device for skin rejuvenation that simultaneously emits low level light, low-dose radiofrequency, low-energy microcurrent, and low-intensity ultrasonic wave. This prospective, randomized, split-face clinical trial enrolled 36 healthy Korean women. After 8 weeks of device use, parameters associated with skin aging were assessed. Additionally, a preliminary ex vivo study and skin biopsy following device use were performed to confirm safety and efficiency of the device. Parameters associated with skin aging including skin hydration, elasticity, roughness, skin pore size, and eye wrinkle volume showed significant improvements after 8 weeks of the device use, relative to baseline measurements and the control side. No adverse effects were observed during the follow-up period. Results of ex vivo and in vivo skin tissue studies correlated with clinical findings, which showed an increase in the expression of type 1 collagen and a decrease in the expression of matrix metalloproteinase-1, which is related to the skin aging phenotype. The expression of loricrin and involucrin, major components of the epidermal skin barrier, also increased after the use of the device. Multi-energy-based device is effective for skin rejuvenation and tolerable, without any considerable adverse effects.
MeSH term(s)	Female ; Humans ; Rejuvenation ; Prospective Studies ; Skin ; Epidermis ; Biopsy
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	632808-8
ISSN	1435-604X ; 0268-8921
ISSN (online)	1435-604X
ISSN	0268-8921
DOI	10.1007/s10103-024-03982-8
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Article ; Online: Biomechanical deficits in patients at 3 months following total knee arthroplasty.

Lee, In-Hee

Journal of back and musculoskeletal rehabilitation

2016 Volume 29, Issue 3, Page(s) 439–444

Abstract: Objectives: This study aimed to evaluate functional biomechanics in patients who undergo total knee arthroplasty (TKA).: Methods: Lower limb joint kinematics and kinetics were evaluated in 25 TKA patients at 3 months following TKA and 25 age-matched ... ...

Abstract	Objectives: This study aimed to evaluate functional biomechanics in patients who undergo total knee arthroplasty (TKA). Methods: Lower limb joint kinematics and kinetics were evaluated in 25 TKA patients at 3 months following TKA and 25 age-matched controls after 12 months following TKA. Participants were evaluated in a gait laboratory, with self-selected gait speed. Results: Experimental group walked significantly slower (p < 0.01), using a shorter stride length (p < 0.01), compared to those for the controls. The experimental group exhibited significantly greater knee motion, lower knee extension moment (p < 0.01), and lower peak power generation (p < 0.01) compared to those for the control group. Additionally, the TKA group showed significantly smaller peak ankle motion (p < 0.01), lower ankle dorsiflexion moments (p < 0.05), and ankle power generation (p < 0.01) compared to those for the control group. Discussion: These biomechanical properties of gait in the experimental group may be a compensatory response to lesser recovered knee function to allow sufficient power generation for propulsion. Therefore, rehabilitative strategies at 3 months following TKA are needed to improve not only knee function but also hip and ankle function after TKA.
MeSH term(s)	Aged ; Ankle Joint/physiopathology ; Arthroplasty, Replacement, Knee ; Biomechanical Phenomena/physiology ; Case-Control Studies ; Female ; Gait/physiology ; Humans ; Knee Joint/physiopathology ; Knee Joint/surgery ; Male ; Osteoarthritis, Knee/physiopathology ; Osteoarthritis, Knee/surgery ; Range of Motion, Articular/physiology
Language	English
Publishing date	2016-08-10
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1184721-9
ISSN	1878-6324 ; 1053-8127
ISSN (online)	1878-6324
ISSN	1053-8127
DOI	10.3233/BMR-150635
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