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  1. Article ; Online: Paradoxical eruption exclusively located at ear in psoriatic patients treated with biologics: a case series.

    Burlando, Martina / Salvi, Ilaria / Parodi, Aurora / Cozzani, Emanuele C

    Clinical and experimental dermatology

    2024  

    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llae054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Psoriasis flares after COVID-19 vaccination: adherence to biologic therapy reduces psoriasis exacerbations: a case-control study.

    Burlando, Martina / Herzum, Astrid / Cozzani, Emanuele / Parodi, Aurora

    Clinical and experimental vaccine research

    2023  Volume 12, Issue 1, Page(s) 80–81

    Abstract: This study aimed to evaluate if patients under biologics have a lower risk of psoriasis flares after coronavirus disease 2019 (COVID-19) vaccination than other psoriatic patients. Of 322 recently vaccinated patients admitted for psoriasis at the ... ...

    Abstract This study aimed to evaluate if patients under biologics have a lower risk of psoriasis flares after coronavirus disease 2019 (COVID-19) vaccination than other psoriatic patients. Of 322 recently vaccinated patients admitted for psoriasis at the Dermatological Psoriasis Unit during January and February 2022, 316 (98%) had no psoriasis flares after COVID-19 vaccination (79% under biologic treatment, 21% not biologically treated) and 6 (2%) presented psoriasis flares after COVID-19 vaccination (33.3% under biologic treatment, 66.6% not biologically treated). Overall, psoriasis patients under biologic treatment, developed fewer psoriasis flares after COVID-19 vaccination (33.3%), than patients not under biologic treatment (66.6%) (p=0.0207; Fisher's exact test).
    Language English
    Publishing date 2023-01-31
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2684652-4
    ISSN 2287-366X ; 2287-3651
    ISSN (online) 2287-366X
    ISSN 2287-3651
    DOI 10.7774/cevr.2023.12.1.80
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Results of COVID-19 screening in a dermatologic clinic in Northern Italy.

    Burlando, Martina / Boldrin, Samuele / Salvi, Ilaria / Cozzani, Emanuele / Parodi, Aurora

    Journal of preventive medicine and hygiene

    2023  Volume 64, Issue 1, Page(s) E1–E2

    MeSH term(s) Humans ; COVID-19 ; Skin Diseases ; SARS-CoV-2 ; Italy/epidemiology
    Language English
    Publishing date 2023-05-16
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1102926-2
    ISSN 2421-4248 ; 1121-2233
    ISSN (online) 2421-4248
    ISSN 1121-2233
    DOI 10.15167/2421-4248/jpmh2023.64.1.2544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tildrakizumab: the value of a personalized and flexible approach for treating moderate-to-severe plaque psoriasis in patients with high body weight or high disease burden.

    Dapavo, Paolo / Burlando, Martina / Guarneri, Claudio / Megna, Matteo / Narcisi, Alessandra / Talamonti, Marina / Gisondi, Paolo

    Expert opinion on biological therapy

    2024  Volume 24, Issue 3, Page(s) 133–138

    Abstract: Introduction: The introduction of biologics for the treatment of plaque psoriasis is one of the major therapeutic advances of the last decades in dermatology. The efficacy of this class of drugs can be influenced by multiple factors including obesity, ... ...

    Abstract Introduction: The introduction of biologics for the treatment of plaque psoriasis is one of the major therapeutic advances of the last decades in dermatology. The efficacy of this class of drugs can be influenced by multiple factors including obesity, being overweight, prior treatment failures, and disease severity.
    Areas covered: Most of the currently available approved biologics are limited by their lack of dosing flexibility for adapting the therapy to the complexity of real-world patients with psoriasis. Among the class of anti-interleukin-23, tildrakizumab allows a greater dosing flexibility, increasing clinical benefits of patients with high burden of the disease or body weight >90 kg.
    Expert opinion: This meta-opinion discusses the clinical data that were foundational for tildrakizumab dosage flexibility, elaborates on the definition of high burden of disease specifically linked to tildrakizumab dosage, and profiles the ideal patient that could benefit from treatment with the higher approved tildrakizumab dosage of 200 mg.
    MeSH term(s) Humans ; Antibodies, Monoclonal/therapeutic use ; Overweight/drug therapy ; Treatment Outcome ; Psoriasis/diagnosis ; Psoriasis/drug therapy ; Cost of Illness ; Severity of Illness Index ; Body Weight ; Biological Products/therapeutic use ; Antibodies, Monoclonal, Humanized
    Chemical Substances tildrakizumab (DEW6X41BEK) ; Antibodies, Monoclonal ; Biological Products ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2052501-1
    ISSN 1744-7682 ; 1471-2598
    ISSN (online) 1744-7682
    ISSN 1471-2598
    DOI 10.1080/14712598.2024.2325547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: "De Novo" Psoriasis and Relapse of Psoriasis Induced by Dupilumab: Three New Cases and Review of the Literature.

    Trave, Ilaria / Salvi, Ilaria / Burlando, Martina / Cozzani, Emanuele / Parodi, Aurora

    Journal of clinical medicine

    2023  Volume 12, Issue 19

    Abstract: Atopic dermatitis and psoriasis are traditionally considered diseases that cannot coexist, since they are described as the result of the activation of opposing inflammatory pathways. However, this belief has been debunked, and numerous cases of psoriasis ...

    Abstract Atopic dermatitis and psoriasis are traditionally considered diseases that cannot coexist, since they are described as the result of the activation of opposing inflammatory pathways. However, this belief has been debunked, and numerous cases of psoriasis induced by dupilumab, a biologic treatment for atopic dermatitis, have been reported. We report three cases of dupilumab-induced psoriasis and we present a literature review including cases of "de novo" psoriasis and of the relapse of psoriasis that occurred during treatment with dupilumab. In total, 39 publications met the inclusion criteria, including 112 AD patients, 101 of whom developed "de novo" psoriasis, and 11 with a flare of pre-existent psoriasis. In the first group, patients more frequently developed plaque psoriasis on the scalp and extremities, after an average latency period from the initiation of dupilumab of 5 months. In the second group, the incidence of dupilumab-induced relapses of psoriasis was 43%, after an average of 4 months since the first administration. The most common psoriasis type was plaque psoriasis, with the involvement of the scalp and upper extremities. Dupilumab was interrupted in 38% of patients with "de novo" psoriasis and in 50% of relapsed patients, leading, in most cases, to an improvement of psoriasis. In conclusion, atopic dermatitis and psoriasis can definitely co-exist, and biologic drugs used to treat the former can promote the latter. It is thus crucial to perform a careful personal and familiar anamnesis before prescribing any biologic treatment. Moreover, a study of cytokine expression and blood proteomic markers could be considered in these patients.
    Language English
    Publishing date 2023-09-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12196291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A novel moisture for xerosis in psoriatic patients: a single center study.

    Burlando, Martina / Castelli, Riccardo / Salvi, Ilaria / Cozzani, Emanuele / Parodi, Aurora

    Italian journal of dermatology and venereology

    2023  Volume 158, Issue 1, Page(s) 39–41

    Abstract: Background: Xerosis is an extremely common condition, especially in the elderly population. It is the most common cause of pruritus in the older adult. Since xerosis is generally caused by a lack of epidermal lipids, the use of leave-on skin care ... ...

    Abstract Background: Xerosis is an extremely common condition, especially in the elderly population. It is the most common cause of pruritus in the older adult. Since xerosis is generally caused by a lack of epidermal lipids, the use of leave-on skin care products is the mainstay treatment. The aim of this open prospective analytical observational study was to investigate the clinical and self-reported hydrating efficacy of a moisturizer formulation containing a synergy between amino-inositol and urea (INOSIT-U 20) in patients with psoriasis and xerosis.
    Methods: Twenty-two patients with psoriasis successfully treated with biologic therapy, and who presented xerosis, were recruited. Each patient was instructed to apply the topical with a frequency of two applications per die on the identified skin area. Corneometry values and a VAS itch questionnaire were measured at baseline (T0) and after 28 days (T4). To evaluate the cosmetic efficacy, the volunteers also completed a self-assessment questionnaire.
    Results: Comparing Corneometry values at T0 and T4, a statistically significant increase value was observed in the area subjected to topical treatment (P<0.0001). A significant decrease in itch (P=0.001) was also observed. Moreover, the patients' ratings of the cosmetic properties of the moisturizer showed significant confirmation rates.
    Conclusions: This study provides preliminary evidence that INOSIT-U20 provides a good hydrating effect on xerosis, further reducing self-reported itch.
    MeSH term(s) Humans ; Aged ; Emollients/therapeutic use ; Prospective Studies ; Pruritus/drug therapy ; Pruritus/etiology ; Skin Diseases/complications ; Autonomic Nervous System Diseases/complications ; Autonomic Nervous System Diseases/drug therapy ; Psoriasis/complications ; Psoriasis/drug therapy
    Chemical Substances Emollients
    Language English
    Publishing date 2023-02-21
    Publishing country Italy
    Document type Observational Study ; Journal Article
    ZDB-ID 3065415-4
    ISSN 2784-8450
    ISSN (online) 2784-8450
    DOI 10.23736/S2784-8671.23.07364-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A purplish plaque and multiple nodules on the arm.

    Burlando, Martina / Salvi, Ilaria / Guadagno, Antonio / Cozzani, Emanuele / Parodi, Aurora

    JAAD case reports

    2022  Volume 31, Page(s) 10–12

    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2022.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Erythema dyschromicum perstans (ashy dermatosis) unter Dimethylfumarat.

    Burlando, Martina / Salvi, Ilaria / Guadagno, Antonio / Cozzani, Emanuele / Parodi, Aurora

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 11, Page(s) 1502–1504

    Language English
    Publishing date 2022-11-16
    Publishing country Germany
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14889_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dimethyl fumarate-associated ashy dermatosis.

    Burlando, Martina / Salvi, Ilaria / Guadagno, Antonio / Cozzani, Emanuele / Parodi, Aurora

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2022  Volume 20, Issue 11, Page(s) 1502–1504

    MeSH term(s) Humans ; Dimethyl Fumarate/adverse effects ; Hyperpigmentation
    Chemical Substances Dimethyl Fumarate (FO2303MNI2)
    Language English
    Publishing date 2022-11-10
    Publishing country Germany
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 "second wave" and vaccines: the dermatologists' perspective.

    Burlando, Martina / Russo, Roberto / Cozzani, Emanuele / Parodi, Aurora

    International journal of dermatology

    2021  Volume 60, Issue 7, Page(s) 889–890

    MeSH term(s) COVID-19 ; Dermatologists ; Dermatology ; Humans ; SARS-CoV-2 ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2021-03-25
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.15547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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